Protein
MCA_05567_1
Length
1,478 amino acids
Gene name: SAK1
Description: SNF1-activating kinase 1; in S. cerevisiae plays a role in pseudohyphal growth
Browser: contigD:1665192-1669707-
RNA-seq: read pairs 1133, FPKM 9.5, percentile rank 25.1% (100% = highest expression)
Protein function
| Annotation: | SAK1 | SNF1-activating kinase 1; in S. cerevisiae plays a role in pseudohyphal growth | |
|---|---|---|---|
| KEGG: | K21157 | SAK1 | SNF1-activating kinase 1 [EC:2.7.11.1] |
| EGGNOG: | 0PHIQ | PGUG_04818 | calcium calmodulin-dependent protein kinase |
| SGD closest match: | S000000931 | SAK1 | SNF1-activating kinase 1 |
| CGD closest match: | CAL0000198568 | orf19.3840 | Serine/threonine protein kinase |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_00922_1 | 71.23% | 424 | 0.0 | MIA_00922_1 |
| A0A0J9XKL3_GEOCN | 57.55% | 417 | 1e-144 | Similar to Saccharomyces cerevisiae YER129W SAK1 Upstream serine/threonine kinase for the SNF1 complex OS=Geotrichum candidum GN=BN980_GECA23s01187g PE=4 SV=1 |
| UniRef50_A0A0J9XKL3 | 57.55% | 417 | 2e-141 | Similar to Saccharomyces cerevisiae YER129W SAK1 Upstream serine/threonine kinase for the SNF1 complex n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XKL3_GEOCN |
| A0A060T510_BLAAD | 55.86% | 435 | 6e-143 | ARAD1B00550p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B00550g PE=4 SV=1 |
| A0A167FVJ4_9ASCO | 55.88% | 417 | 3e-135 | Serine/threonine protein kinase SAK1 OS=Sugiyamaella lignohabitans GN=SAK1 PE=4 SV=1 |
| A0A1E3PL82_9ASCO | 50.35% | 425 | 2e-117 | Kinase-like protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_82625 PE=4 SV=1 |
| Q6C9S1_YARLI | 61.82% | 275 | 1e-104 | YALI0D08822p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D08822g PE=4 SV=1 |
| Q5A650_CANAL | 42.29% | 480 | 6e-95 | Serine/threonine protein kinase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.3840 PE=4 SV=1 |
| A0A1E4TAY6_9ASCO | 52.99% | 334 | 4e-103 | Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_13094 PE=3 SV=1 |
| SAK1_YEAST | 42.92% | 438 | 1e-87 | SNF1-activating kinase 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SAK1 PE=1 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.7799
Protein family membership
None predicted.
Domains and repeats
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Domain
1
200
400
600
800
1000
1200
1478
Detailed signature matches
no IPR
Unintegrated signatures
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NON_CYTOPLASM... (N...)
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SIGNAL_PEPTIDE (Sig...)
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SIGNAL_PEPTID... (S...)
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SIGNAL_PEPTID... (S...)
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SIGNAL_PEPTID... (S...)
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cd14008 (STKc_LKB1_...)
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mobidb-lite (disord...)
Residue annotation
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ATP binding site c...
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active site cd14008
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polypeptide substr...
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activation loop (A...
Protein sequence
>MCA_05567_1 MTLKGSKAKLSALLPSLSSSSSSLVNKEKEKEKGKEKEKERGKRISSLLSTPNTTNPPSVNSSIASSPTSTSYTSVRGDK SSSETTSKHKKSISQLSCESRSQSSDFQHTLINVLSSVSLRSRSKSRHRSSNSASTSNSTTNLSGNDNAQSSKSAIGLSS SKNEDSSSLNDRPCNSSRSNCGQKQPIGQPPTNTNVYGSKFPLPLNSASSFSSINSSASARSPSSFNNYSHQNDSVTSSA SNSPYLSSTTHSRNASFSNQPHSKSSYSNSTAALRAPHLSSDRNPSSSLSDINSKLETFAQKKPSMLQPAYNFNQNQSSQ LQRQPSNESNRPDSASSAASSCSIPSSPTSSTVKETNYININIDPVSGHKLINTYEILSELGRGQHGKVKLARNIETSEL VAIKIIDRIGKPKLGSLRAGNTHEDKVKREIAIMKKCHHPNIVCLLEVLDDSSSKTNKIYLVLEYLEKGELHWQDAKGNP ILSMEQARDVARDVISGLEYLHFQGIIHRDIKPANLLRDQNGTVKISDFGVSYATSLNNGTNDELELAKTAGTPAFFAPE LCAPIPADGGPRPPITKKIDIWAFGVTLFCLIYGKLPFSAESEFELFQVIANEPLVFPDEVSEFPVPKKNKNFHSIFYNQ PTGDNCEKQSTLEEEEAKDEATQAPSITVTPDPKLKEVKDLLRKLLEKDPVKRIDMEDIKHHPWIMDGMDQPLLEHFLTN TASEQKIDVTTEEVQEAVSGIGSRIKRGLSRFRSHIAKGLTRKSSSSSSSVNQSSENSRSNSRDAPSSIARRNIKYFDKT VFSNGHESDFSNSSSRVPSSISHTSKNHNDSSIMESTLSLNKSACSSYSSLSSMSSSVNFSTSPQTNFHSHRDFSHTQDS MRSSSRNFYPNAHTRRGSRTLSVSSMISNDNASRTNSPDTPIMHVIPMETNSSLDSERSAALSRESHIMSGMKLHQDNLR HISESMSRNTSLSSSYSRRSNSPPLANLDHRPLSLGKLTTSSNNLNLHGVLSNSSESSSSPTVGLDNKLHRDEFPNSNSN SEESTRYTFNVNTDLDDNGRAAYSGSNTPIASSNPSFNSSRGGFSNNISNTLHIYSDADRSSNVSTSADGDIPREFEERP SEQESATQLSSISTVKPSTLASSTQNPPHSNNNVYNMAPSNATNISTGSTRSFASTVSSSDDEGGLTLVVDREPHNSREG SSLDPRSDSNKRTISTVSRLVSTGSSGIKHPNPINRLGSSAASTSRYVSRIVPPQDTRAQPSLATSRRMSAYDDMEPIIK KHTFRESYTPSTTFSATNQRSNPEPLPKSPKSSFSQIASSSESSSDPTRSSRQAGSTAETSQTSIHEIVDVPSCIALDSL GSNYGGYYGNEEDYCFGQQSGSNNNYHTKTHTNSITSQASTQSSDDGLNLSFKPYPGYTRGRSHSVAVGQVQYNRQFMNS AVNDGLVETTPDDIINNECDNDGQESDDSSSEDEMLYI
GO term prediction
Biological Process
GO:0006468 protein phosphorylation
Molecular Function
GO:0004672 protein kinase activity
GO:0005524 ATP binding
Cellular Component
None predicted.