Protein

MIA_00889_1

Length
248 amino acids

Browser: contig01:2508400-2509204-

Protein function

EGGNOG:0PHCCMDE1Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
SGD closest match:S000003785MDE1Methylthioribulose-1-phosphate dehydratase
CGD closest match:CAL0000179829MDE1Methylthioribulose-1-phosphate dehydratase

Protein alignments

%idAln lengthE-value
A0A0J9XHS1_GEOCN73.878%2451.06e-139Methylthioribulose-1-phosphate dehydratase OS=Geotrichum candidum GN=MDE1 PE=3 SV=1
MCA_05569_175.417%2409.02e-137MCA_05569_1
A0A060T4F5_BLAAD72.000%2259.67e-124Methylthioribulose-1-phosphate dehydratase OS=Blastobotrys adeninivorans GN=MDE1 PE=3 SV=1
A0A1E3PPI5_9ASCO67.111%2251.68e-117Methylthioribulose-1-phosphate dehydratase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=MDE1 PE=3 SV=1
MTNB_YARLI66.234%2318.32e-116Methylthioribulose-1-phosphate dehydratase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=MDE1 PE=3 SV=1
UniRef50_A3LVM959.574%2351.86e-90Methylthioribulose-1-phosphate dehydratase n=37 Tax=saccharomyceta TaxID=716545 RepID=MTNB_PICST
MTNB_CANAL60.086%2331.69e-93Methylthioribulose-1-phosphate dehydratase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=MDE1 PE=3 SV=1
MTNB_YEAST58.228%2374.12e-90Methylthioribulose-1-phosphate dehydratase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MDE1 PE=1 SV=1
A0A167CHH7_9ASCO66.667%1713.54e-84Methylthioribulose 1-phosphate dehydratase MDE1 OS=Sugiyamaella lignohabitans GN=MDE1 PE=4 SV=1
A0A1E4TJX1_9ASCO33.333%2168.02e-26Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_30334 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.2231

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 248

Detailed signature matches

  1. Family IPR017714
    Methylthioribulose-1-phosphate dehydratase
    1. TIGR03328
  2. Family IPR027514
    Methylthioribulose-1-phosphate dehydratase, eukaryotes
    1. MF_03116 (Salvage_M...)
  3. Domain IPR001303
    Class II aldolase/adducin N-terminal
    1. SSF53639 (AraD/HMP-...)
    2. SM01007 (Aldolase_II_2)
    3. G3DSA:3.40.22...
    4. PF00596 (Aldolase_II)

Protein sequence

>MIA_00889_1
MSSAPVVRKATGPDSLVISDDCNHPANVICELCRLFFDKDWVTGTGGGMSIRQDNLVYLAPSGVQKERMKPENMFVMDLK
TKDYLKTPDTYKPSACTPLFLSIYDAADAGACIHTHSQAAVMVSLLYDKEFRISNIEQIKAVPRIIETGYLDNTDELVIP
IIENTLQEEDLTPYLAKTLKEYPAASAVIVRRHGIFVWGANIWKAKIINEAIDYLLELAVKMRSFGINTTGPLGIEKKSP
YHECNNQH

GO term prediction

Biological Process

GO:0019509 L-methionine salvage from methylthioadenosine

Molecular Function

GO:0046872 metal ion binding

Cellular Component

GO:0005737 cytoplasm