Protein

MIA_00839_1

Length
805 amino acids

Browser: contig01:2379743-2382161-

Protein function

EGGNOG:0PH8KDRS1ATP-dependent RNA helicase DRS1
SGD closest match:S000003931DRS1ATP-dependent RNA helicase DRS1
CGD closest match:CAL0000182242DRS1ATP-dependent RNA helicase DRS1

Protein alignments

%idAln lengthE-value
MCA_02296_157.598%8160.0MCA_02296_1
A0A0J9X5S4_GEOCN55.497%7550.0Similar to Saccharomyces cerevisiae YLL008W DRS1 Nucleolar DEAD-box protein required for ribosome assembly and function, including synthesis of 60S ribosomal subunit OS=Geotrichum candidum GN=BN980_GECA03s02705g PE=3 SV=1
A0A167DUY4_9ASCO60.714%6160.0Drs1p OS=Sugiyamaella lignohabitans GN=DRS1 PE=3 SV=1
A0A060T316_BLAAD52.877%7300.0ARAD1C33462p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C33462g PE=3 SV=1
A0A1E3PHR1_9ASCO64.404%5450.0DEAD-domain-containing protein (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_4669 PE=3 SV=1
UniRef50_Q75F9551.499%7340.0ATP-dependent RNA helicase DRS1 n=23 Tax=Saccharomycetales TaxID=4892 RepID=DRS1_ASHGO
DRS1_YEAST59.294%5380.0ATP-dependent RNA helicase DRS1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=DRS1 PE=1 SV=2
DRS1_YARLI66.186%4850.0ATP-dependent RNA helicase DRS1 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=DRS1 PE=3 SV=1
DRS1_CANAL50.351%7130.0ATP-dependent RNA helicase DRS1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=DRS1 PE=3 SV=1
A0A1E4TFG2_9ASCO58.367%4902.28e-180Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_37291 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.6257

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
  3. Domain
1 100 200 300 400 500 600 700 805

Detailed signature matches

  1. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
  2. Domain IPR014014
    RNA helicase, DEAD-box type, Q motif
    1. PS51195 (Q_MOTIF)
  3. Domain IPR014001
    Helicase superfamily 1/2, ATP-binding domain
    1. PS51192 (HELICASE_A...)
    2. SM00487 (ultradead3)
  4. Domain IPR011545
    DEAD/DEAH box helicase domain
    1. PF00270 (DEAD)
  5. Domain IPR001650
    Helicase, C-terminal
    1. PS51194 (HELICASE_CTER)
    2. SM00490 (helicmild6)
    3. PF00271 (Helicase_C)
  6. SITE IPR000629
    ATP-dependent RNA helicase DEAD-box, conserved site
    1. PS00039 (DEAD_ATP_H...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:3.40.50...
  3. cd00079 (HELICc)
  4. cd00268 (DEADc)
  5. mobidb-lite (disord...)

Residue annotation

  1. ATP binding site c...
  2. Mg++ binding site ...
  3. motif III cd00268
  4. nucleotide binding...
  5. ATP-binding site c...

Protein sequence

>MIA_00839_1
MASAKKGNKAALKSASKTQPKNGSKAVLKNDSKSESKATPKNTSQKEANPEPKNASKSKQRKSLDDDFVMTISDDEEVIV
AEESSDEEGKKEIPDADKAPKKKAKKNKKNATKEEEAGPEGMSLDPEFVFDTGDGSVAIDEEFGGWDFEVPDKKKTISKD
VDLDEIIRRKGGLDNASDSEDEKADEQDDDDLALDGFGMGAQDDEEENDGEEGEGDESEEEEETDLPQNHEDTPQEIAKF
YAPQTESVRATSTVHKTFQELSLSRPVLRGIAALKFSEPTPIQNAVIPIALLGKDIVAGAVTGSGKTAAYLIPILERLAY
LPKKVAMTRVVVLTPTRELAVQVSDVATRLSQFLGSIRVGQAVGGLNLKQQEQVLKSRPDIVVATPGRFIDHVRNSPSFQ
VDAVEILVIDEADRMLEAGFQAELTELLSLLPQKRQTLLFSATMNNSIKDLIQLSLNKPVRIMINPPKQAAGGLVQEFIR
TRNDKLEYKPAVLLWLLKKILDCQSIKQRIIVFVARKEAAHKLRIILGLQGVHVGELHGALTQEQRLQSVTRFKNLEVPI
LLCTDLASRGLDIPKIEVVINYDMPSTYEVYLHRVGRTARAGRQGRSISLVGESSSDRSIAREAIKSSMGADDKQPKKKK
NKFVTRTIDWEYVQPVYESMESKEETVTEILEEEKTEKMMAQAQRELTKSQNLLKHEAEIKSRPKRTWFETQADKMKSKY
GTGPEDQQAKKADDAKKLVRDHPVLGAQLPKKQKRADTVGDGEGGRAYKKTKVERDESKKRGGPKKTKNGKKQQAKIARA
KKYRK

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0003676 nucleic acid binding
GO:0005524 ATP binding

Cellular Component

None predicted.