Protein

MCA_02296_1

Length
824 amino acids

Gene name: DRS1

Description: ATP-dependent RNA helicase DRS1

Browser: contigB:840109-842584+

RNA-seq: read pairs 1862, FPKM 27.9, percentile rank 50.5% (100% = highest expression)

Protein function

Annotation:DRS1ATP-dependent RNA helicase DRS1
KEGG:K13181DDX27 ATP-dependent RNA helicase DDX27 [EC:3.6.4.13]
EGGNOG:0PH8KDRS1ATP-dependent RNA helicase DRS1
SGD closest match:S000003931DRS1ATP-dependent RNA helicase DRS1
CGD closest match:CAL0000182242DRS1ATP-dependent RNA helicase DRS1

Protein alignments

%idAln lengthE-value
MIA_00839_159.92%7710.0MIA_00839_1
A0A0J9X5S4_GEOCN53.80%6710.0Similar to Saccharomyces cerevisiae YLL008W DRS1 Nucleolar DEAD-box protein required for ribosome assembly and function, including synthesis of 60S ribosomal subunit OS=Geotrichum candidum GN=BN980_GECA03s02705g PE=3 SV=1
A0A167DUY4_9ASCO52.91%6520.0Drs1p OS=Sugiyamaella lignohabitans GN=DRS1 PE=3 SV=1
A0A060T316_BLAAD50.67%6690.0ARAD1C33462p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C33462g PE=3 SV=1
UniRef50_Q75F9549.10%6680.0ATP-dependent RNA helicase DRS1 n=23 Tax=Saccharomycetales TaxID=4892 RepID=DRS1_ASHGO
A0A1E3PHR1_9ASCO50.70%7180.0DEAD-domain-containing protein (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_4669 PE=3 SV=1
DRS1_CANAL53.59%6120.0ATP-dependent RNA helicase DRS1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=DRS1 PE=3 SV=1
DRS1_YEAST49.64%6990.0ATP-dependent RNA helicase DRS1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=DRS1 PE=1 SV=2
DRS1_YARLI51.26%6340.0ATP-dependent RNA helicase DRS1 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=DRS1 PE=3 SV=1
A0A1E4TFG2_9ASCO55.31%4905e-169Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_37291 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9874
Predicted cleavage: 16

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 600 700 824

Detailed signature matches

  1. Domain IPR014014
    RNA helicase, DEAD-box type, Q motif
    1. PS51195 (Q_MOTIF)
  2. Domain IPR014001
    Helicase superfamily 1/2, ATP-binding domain
    1. PS51192 (HELICASE_A...)
    2. SM00487 (ultradead3)
  3. Domain IPR011545
    DEAD/DEAH box helicase domain
    1. PF00270 (DEAD)
  4. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
  5. Domain IPR001650
    Helicase, C-terminal
    1. PS51194 (HELICASE_CTER)
    2. SM00490 (helicmild6)
    3. PF00271 (Helicase_C)
  6. SITE IPR000629
    ATP-dependent RNA helicase DEAD-box, conserved site
    1. PS00039 (DEAD_ATP_H...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:3.40.50...
  3. cd00079 (HELICc)
  4. cd00268 (DEADc)
  5. mobidb-lite (disord...)

Residue annotation

  1. ATP binding site c...
  2. Mg++ binding site ...
  3. motif III cd00268
  4. nucleotide binding...
  5. ATP-binding site c...

Protein sequence

>MCA_02296_1
MAKNKKGNQKIVKRNGGSITNTQANAKQSPAKPATPSKQAAKSSAKQAAKSSVKQASKPAAPKPKLIDDEFVMTISDSEE
VAVADESTDDEKDAEENEEPAVAPKKKVKKNKKQEKSNGPQQNSEFNLDFEFDDGTQKLLVEDEGWNFDVPNKKKHAREV
DLDEIIRKKGGLDNAQTSDEEQDDSDDDDLAMDGFGMGSKEDEDGEEEDEEKEKEEEEESGSEEEDKEEFNANAKYSRYA
QPQDSAEALSKFYESSKIYTTTSAAEAAAGKSFQDLQLSRPVLRGIASLNFTSPTPIQNSVIPLALLGKDIVAGAVTGSG
KTGAYLIPILERLAHLPKKIALTRVLILTPTRELAIQVSDVATKLSKFMPNIAIGQAIGGLNLKQQEKALKSRPDIVIAT
PGRFIDHVRNSPSFQVDGVEILVIDEADRMLEQGFHEELNEILNMLPQNSKRQTLLFSATMNSSINDLIQLSLNKPSRIQ
ISPAESVAENLVQEFIKVRNKMIAYKPSILYWLLKKVLDCNHVKQKIIIFVNRKDDAHKLRIIMGLFGIHIGELHGGLTQ
EQRVASVTRFSNMEVPILICTDLAARGLDIPNVRVVINYDLPAVYETYQHRVGRTARAGRDGRSISLVLETASDRSIARD
AIRKSTQAKVTGKFVTRSIDWEYVNEMQKGFEEKEEVLKEVLEEERTEKLLAQAEREITKSENLIKHEAEIKSRPKRTWF
ESQADSISKHRSGPLTDQERQAKRAEDARKKVIDHPSLGAQLPKAKKAKVDDDDASSKVYKKTKTDRDTDHKLTMLRKNS
KKTVSKKNDKKVQAKIARAKKYKK

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0003676 nucleic acid binding
GO:0005524 ATP binding

Cellular Component

None predicted.