Protein

MIA_00822_1

Length
189 amino acids

Browser: contig01:2325286-2325921+

Protein function

EGGNOG:0PHNNPGUG_02674guanylate kinase
SGD closest match:S000002862GUK1Guanylate kinase
CGD closest match:CAL0000178615GUK1Guanylate kinase

Protein alignments

%idAln lengthE-value
MCA_06377_179.144%1873.97e-112MCA_06377_1
A0A0J9XFH8_GEOCN73.262%1872.48e-102Similar to Saccharomyces cerevisiae YDR454C GUK1 Guanylate kinase OS=Geotrichum candidum GN=BN980_GECA13s02584g PE=3 SV=1
A0A1D8PNS0_CANAL75.410%1835.38e-102Guanylate kinase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=GUK1 PE=3 SV=1
UniRef50_A0A1D8PNS075.410%1831.30e-98Guanylate kinase n=21 Tax=Eukaryota TaxID=2759 RepID=A0A1D8PNS0_CANAL
A0A1E3PF16_9ASCO73.913%1849.03e-102Guanylate kinase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_27567 PE=4 SV=1
A0A060SZN7_BLAAD73.514%1853.22e-101ARAD1C09702p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C09702g PE=4 SV=1
Q6CBQ9_YARLI69.355%1861.62e-97YALI0C16434p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C16434g PE=3 SV=1
KGUA_YEAST72.432%1854.63e-97Guanylate kinase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GUK1 PE=1 SV=2
A0A167E6M5_9ASCO73.171%823.48e-39Guanylate kinase OS=Sugiyamaella lignohabitans GN=GUK1 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.8510
Predicted cleavage: 14

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 20 40 60 80 100 120 140 160 189

Detailed signature matches

  1. Family IPR017665
    Guanylate kinase
    1. TIGR03263
  2. Domain IPR008144
    Guanylate kinase-like domain
    1. PS50052 (GUANYLATE_...)
  3. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
  4. Domain IPR008145
    Guanylate kinase/L-type calcium channel beta subunit
    1. SM00072 (gk_7)
    2. PF00625 (Guanylate_kin)
  5. SITE IPR020590
    Guanylate kinase, conserved site
    1. PS00856 (GUANYLATE_...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:3.30.63.10
  3. G3DSA:3.40.50...
  4. cd00071 (GMPK)

Residue annotation

  1. G-X2-G-X-G-K cd00071
  2. catalytic site cd0...

Protein sequence

>MIA_00822_1
MSVRPIVVSGPSGTGKSTLLKKLFAEYPDKFGFSVSHTTRSPRPGEVNGKDYNFVTVDEFKNLIDGQGFIEWAQFSGNYY
GTSIDAVKSVLEKDNRICILDIDMQGVKSVKNTDLNARFLFLAPPSLEDLEARLTGRGTESAESLEKRLKQAEVELEYAK
EPGAHDKIIVNEDLDKAYQEFRDFMLANE

GO term prediction

Biological Process

GO:0006163 purine nucleotide metabolic process

Molecular Function

GO:0004385 guanylate kinase activity

Cellular Component

None predicted.