Protein
MIA_00817_1
Length
676 amino acids
Browser: contig01:2312310-2314396-
Protein function
| EGGNOG: | 0PHYC | NHX1 | Sodium hydrogen exchanger |
|---|---|---|---|
| SGD closest match: | S000002864 | NHX1 | Endosomal/prevacuolar sodium/hydrogen exchanger |
| CGD closest match: | CAL0000198193 | NHX1 | Sodium/hydrogen exchanger |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MCA_06372_1 | 73.821% | 615 | 0.0 | MCA_06372_1 |
| A0A0J9XGP0_GEOCN | 69.585% | 651 | 0.0 | Sodium/hydrogen exchanger OS=Geotrichum candidum GN=BN980_GECA13s02628g PE=3 SV=1 |
| A0A060T601_BLAAD | 68.640% | 625 | 0.0 | Sodium/hydrogen exchanger OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C09856g PE=3 SV=1 |
| A0A1E3PGA1_9ASCO | 67.967% | 615 | 0.0 | Sodium/hydrogen exchanger OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_84016 PE=3 SV=1 |
| Q6C362_YARLI | 65.881% | 636 | 0.0 | Sodium/hydrogen exchanger OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F02321g PE=3 SV=1 |
| UniRef50_Q6C362 | 65.881% | 636 | 0.0 | Sodium/hydrogen exchanger n=11 Tax=saccharomyceta TaxID=716545 RepID=Q6C362_YARLI |
| Q59NG8_CANAL | 59.774% | 619 | 0.0 | Sodium/hydrogen exchanger OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=NHX1 PE=3 SV=1 |
| NHX1_YEAST | 58.604% | 616 | 0.0 | Endosomal/prevacuolar sodium/hydrogen exchanger OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NHX1 PE=1 SV=1 |
| A0A1E4TFJ8_9ASCO | 67.265% | 446 | 0.0 | Sodium/hydrogen exchanger (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_20571 PE=3 SV=1 |
| A0A167BZW6_9ASCO | 60.247% | 405 | 7.97e-107 | Bifunctional K:H/Na:H antiporter NHX1 OS=Sugiyamaella lignohabitans GN=NHX1 PE=4 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.2072
Predicted cleavage: 22
Protein family membership
- Na+/H+ exchanger (IPR004709)
Domains and repeats
-
Domain
1
100
200
300
400
500
600
676
Detailed signature matches
-
-
PF00999 (Na_H_Excha...)
-
no IPR
Unintegrated signatures
-
CYTOPLASMIC_D... (C...)
-
NON_CYTOPLASM... (N...)
-
-
TRANSMEMBRANE (Tran...)
-
mobidb-lite (disord...)
Protein sequence
>MIA_00817_1 MLATIQEAGFNLLTSILLKRDSTDADPDIPDDEVSDPTTEEIFTSWALFILIILLIGSLWTSYYLQQKRIQAVHETVISI FSGMVVGLIIRILPGHFIQEHVSFNYSYFFNLLLPPIILNSGYELHQANFFRNIGTILTFAFLGTFLGAIFLGVLLYIWT AIGLEGIQISFLDAISVGATLSATDPVTILSIFNAYKVDPKLYTIIFGESLLNDAVCIVMFETAQKFSGEETLHITSLFK GIGLFLMTFTISLMIGTIVGITTALILKHSHVRRFPQIESCLVLLFAYASYFFSNGCHMSGIVSLLFCGITLRHYAYYNM SRRTQIAVKYIFQLLAQLSENFIFIYLGLSLFTEVELIFKPILIIVTTIGICISRWASVFPLSKLINMFYRRRRAQGNSS SNTGNGSLNQQLQPYQDEIPPQYQMMLFWAGLRGAVGVALAAGLTGEHANSLKATVLVVVVLTVIVFGGTTARMLEILGI RTGVIEEAESDDEFDIEASLGMRYSTSQGHRNNRSRSSAFGGSDLGSYSLDNIAHSSSSRNSKVGIEGGDYDGGARVRRS SSYRDDSASGGDDEMGSDVESDASDLPPMASSTKTGNSGGAPAAGTGSHDASSSSGGLGARTLSGILTRSADDHARWFKE FDEQVLKPVLLDNLPGPSGNSSNSANNSSTSLNSGN
GO term prediction
Biological Process
GO:0006812 cation transport
GO:0006814 sodium ion transport
GO:0006885 regulation of pH
GO:0055085 transmembrane transport
Molecular Function
GO:0015299 solute:proton antiporter activity
GO:0015385 sodium:proton antiporter activity
Cellular Component
GO:0016021 integral component of membrane