MCA_06372_1
Gene name: NHX1
Description: Endosomal/prevacuolar sodium/hydrogen exchanger
Browser: contigD:4012889-4014827-
RNA-seq: read pairs 1704, FPKM 33.7, percentile rank 55.9% (100% = highest expression)
Protein function
| Annotation: | NHX1 | Endosomal/prevacuolar sodium/hydrogen exchanger | |
|---|---|---|---|
| KEGG: | K12041 | SLC9A6_7 | solute carrier family 9 (sodium/hydrogen exchanger), member 6/7 |
| EGGNOG: | 0PHYC | NHX1 | Sodium hydrogen exchanger |
| SGD closest match: | S000002864 | NHX1 | Endosomal/prevacuolar sodium/hydrogen exchanger |
| CGD closest match: | CAL0000198193 | NHX1 | Sodium/hydrogen exchanger |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_00817_1 | 73.52% | 657 | 0.0 | MIA_00817_1 |
| A0A0J9X656_GEOCN | 75.37% | 609 | 0.0 | Sodium/hydrogen exchanger OS=Geotrichum candidum GN=BN980_GECA03s04267g PE=3 SV=1 |
| A0A1E3PGA1_9ASCO | 73.00% | 563 | 0.0 | Sodium/hydrogen exchanger OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_84016 PE=3 SV=1 |
| A0A060T601_BLAAD | 72.05% | 594 | 0.0 | Sodium/hydrogen exchanger OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C09856g PE=3 SV=1 |
| Q6C362_YARLI | 70.40% | 571 | 0.0 | Sodium/hydrogen exchanger OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F02321g PE=3 SV=1 |
| UniRef50_Q6C362 | 70.40% | 571 | 0.0 | Sodium/hydrogen exchanger n=11 Tax=saccharomyceta TaxID=716545 RepID=Q6C362_YARLI |
| NHX1_YEAST | 59.90% | 591 | 0.0 | Endosomal/prevacuolar sodium/hydrogen exchanger OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NHX1 PE=1 SV=1 |
| Q59NG8_CANAL | 72.21% | 457 | 0.0 | Sodium/hydrogen exchanger OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=NHX1 PE=3 SV=1 |
| A0A1E4TFJ8_9ASCO | 57.51% | 579 | 0.0 | Sodium/hydrogen exchanger (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_20571 PE=3 SV=1 |
| A0A167BZW6_9ASCO | 75.10% | 261 | 2e-106 | Bifunctional K:H/Na:H antiporter NHX1 OS=Sugiyamaella lignohabitans GN=NHX1 PE=4 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.1066
Protein family membership
- Na+/H+ exchanger (IPR004709)
Domains and repeats
-
Domain
Detailed signature matches
-
-
PF00999 (Na_H_Excha...)
-
no IPR
-
CYTOPLASMIC_D... (C...)
-
NON_CYTOPLASM... (N...)
-
-
TRANSMEMBRANE (Tran...)
-
mobidb-lite (disord...)
Protein sequence
>MCA_06372_1 MLGSLQKGGLELLTTLLSKRDSTDADPDVPDDEVSDPTTEEIFTSWALFILIILLIGSLWTSYYLQQKRIQAVHETVISI FSGMVVGLIIRVLPGHFIQEHVSFSYSYFFNLLLPPIILNSGYELHQANFFRNMGSILTFAFVGTFIGAIFLGILMYIWT ALGIEGIKISFLDAISLGATLSATDPVTILSIFNAYKVDPKLYTIIFGESLLNDAVCIVMFETAQKFNGQSLHISSLFKG VGMFLMTFTISLMIGTIVGITTALILKHSHVRRFPQIESCLVLLFAYASYFFSNGCHMSGIVSLLFCGITLKHYAYYNMS RRTQIAVKYIFQLLAQLSENFIFIYLGLSLFTEVELVFKPLLIIITAVGICLSRWVAVFPLSKLINFIHRRRAVANHQPI ADEIPPQYQMMLFWAGLRGAVGVALAAGLTGEHANSLKATVLVVVVLTVIVFGGTTARMLEIMGIRTGVIEEAESDDEFD IEASFGNRPVLGTAYSGSNNNGATVSAHSLDSTLSNRVRRSSSYRDSNSEDEDSDVESDVSDLPPMSGRQDSVSMSKLKK PEAGGSSLSGLLSTTVEDHAKWFKKFDDQVLKPVLLDSSPIPSGESGSKSGSNISLDKSHTNPK
GO term prediction
Biological Process
GO:0006812 cation transport
GO:0006814 sodium ion transport
GO:0006885 regulation of pH
GO:0055085 transmembrane transport
Molecular Function
GO:0015299 solute:proton antiporter activity
GO:0015385 sodium:proton antiporter activity
Cellular Component
GO:0016021 integral component of membrane