MIA_00798_1

Protein

Length

712 amino acids

Protein function

EGGNOG:	0PGZM	QNS1	glutamine-dependent NAD( ) synthetase
SGD closest match:	S000001116	QNS1	Glutamine-dependent NAD(+) synthetase
CGD closest match:	CAL0000191648	orf19.1460	Glutamine-dependent NAD(+) synthetase

Protein alignments

	%id	Aln length
MCA_04885_1	80.650%	708	MCA_04885_1
A0A0J9XFX9_GEOCN	75.983%	712	Glutamine-dependent NAD(+) synthetase OS=Geotrichum candidum GN=BN980_GECA15s01462g PE=3 SV=1
A0A161HMU7_9ASCO	74.441%	716	Glutamine-dependent NAD(+) synthetase OS=Sugiyamaella lignohabitans GN=QNS1 PE=3 SV=1
A0A1E3PR42_9ASCO	72.535%	710	Glutamine-dependent NAD(+) synthetase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_48389 PE=3 SV=1
A0A060TI09_BLAAD	73.050%	705	Glutamine-dependent NAD(+) synthetase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D35442g PE=3 SV=1
Q6CGE0_YARLI	71.049%	715	Glutamine-dependent NAD(+) synthetase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_A20108g PE=3 SV=1
A0A1E4TB50_9ASCO	69.101%	712	Glutamine-dependent NAD(+) synthetase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_132553 PE=3 SV=1
UniRef50_A0A163KPC0	65.963%	711	Glutamine-dependent NAD(+) synthetase n=11 Tax=Fungi TaxID=4751 RepID=A0A163KPC0_ABSGL
NADE_YEAST	66.526%	711	Glutamine-dependent NAD(+) synthetase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=QNS1 PE=1 SV=1
Q5ALW6_CANAL	66.014%	715	Glutamine-dependent NAD(+) synthetase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.1460 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1208

Protein family membership

NAD(+) synthetase (IPR003694)
- Glutamine-dependent NAD(+) synthetase (IPR014445)

Domains and repeats

Domain
2 - 299
Carbon-nitrogen hydrolase (IPR003010)
335 - 685
Rossmann-like alpha/beta/alpha sandwich fold (IPR014729)
NAD/GMP synthase (IPR022310)

1 100 200 300 400 500 600 712

Detailed signature matches

IPR003694

NAD(+) synthetase
1. TIGR00552
  
  429 - 662
  
  TIGRFAMs
  TIGR00552 (TIGR00552)
2. cd00553 (NAD_synthase)
  
  332 - 662
  
  CDD
  cd00553 (NAD_synthase)
IPR014445

Glutamine-dependent NAD(+) synthetase
1. PIRSF006630 (NADS_GAT)
  
  2 - 694
  
  PIRSF
  PIRSF006630 (NADS_GAT)
IPR003010

Carbon-nitrogen hydrolase
1. G3DSA:3.60.11...
  
  2 - 287
  
  GENE3D
  G3DSA:3.60.110.10 (G3DSA:3.60.110.10)
2. PS50263 (CN_HYDROLASE)
  
  5 - 299
  
  PROSITE profiles
  PS50263 (CN_HYDROLASE)
3. PF00795 (CN_hydrolase)
  
  7 - 281
  
  Pfam
  PF00795 (CN_hydrolase)
4. SSF56317 (Carbon-ni...)
  
  4 - 288
  
  SUPERFAMILY
  SSF56317 (Carbon-nitrogen hydrolase)
IPR014729

Rossmann-like alpha/beta/alpha sandwich fold
1. G3DSA:3.40.50...
  
  335 - 685
  
  GENE3D
  G3DSA:3.40.50.620 (G3DSA:3.40.50.620)
IPR022310

NAD/GMP synthase
1. PF02540 (NAD_synthase)
  
  344 - 610
  
  Pfam
  PF02540 (NAD_synthase)

no IPR

Unintegrated signatures

SSF52402 (Adenine n...)

324 - 383

SUPERFAMILY
SSF52402 (Adenine nucleotide alpha hydrolases-like)

415 - 674

SUPERFAMILY
SSF52402 (Adenine nucleotide alpha hydrolases-like)
cd07570 (GAT_Gln-NA...)

6 - 286

CDD
cd07570 (GAT_Gln-NAD-synth)

Residue annotation

multimer interface...

16A

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64L, 91Y, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 189A, 192G, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

17L

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64L, 91Y, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 189A, 192G, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

18D

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64L, 91Y, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 189A, 192G, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

19F

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64L, 91Y, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 189A, 192G, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

20E

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64L, 91Y, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 189A, 192G, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

53C

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64L, 91Y, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 189A, 192G, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

54L

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64L, 91Y, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 189A, 192G, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

55D

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64L, 91Y, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 189A, 192G, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

56H

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64L, 91Y, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 189A, 192G, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

58L

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64L, 91Y, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 189A, 192G, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

59E

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64L, 91Y, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 189A, 192G, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

60P

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64L, 91Y, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 189A, 192G, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

61D

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64L, 91Y, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 189A, 192G, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

64L

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64L, 91Y, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 189A, 192G, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

91Y

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64L, 91Y, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 189A, 192G, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

96R

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64L, 91Y, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 189A, 192G, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

97Y

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64L, 91Y, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 189A, 192G, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

116W

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64L, 91Y, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 189A, 192G, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

117M

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64L, 91Y, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 189A, 192G, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

118A

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64L, 91Y, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 189A, 192G, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

120D

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64L, 91Y, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 189A, 192G, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

121G

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64L, 91Y, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 189A, 192G, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

122N

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64L, 91Y, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 189A, 192G, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

124R

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64L, 91Y, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 189A, 192G, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

126L

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64L, 91Y, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 189A, 192G, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

127R

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64L, 91Y, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 189A, 192G, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

130T

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64L, 91Y, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 189A, 192G, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

131P

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64L, 91Y, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 189A, 192G, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

133R

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64L, 91Y, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 189A, 192G, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

176E

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64L, 91Y, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 189A, 192G, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

178L

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64L, 91Y, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 189A, 192G, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

179F

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64L, 91Y, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 189A, 192G, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

180T

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64L, 91Y, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 189A, 192G, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

181P

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64L, 91Y, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 189A, 192G, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

182N

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64L, 91Y, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 189A, 192G, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

186I

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64L, 91Y, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 189A, 192G, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

187K

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64L, 91Y, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 189A, 192G, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

189A

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64L, 91Y, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 189A, 192G, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

192G

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64L, 91Y, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 189A, 192G, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

204H

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64L, 91Y, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 189A, 192G, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

205E

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64L, 91Y, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 189A, 192G, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

206L

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64L, 91Y, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 189A, 192G, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

207R

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64L, 91Y, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 189A, 192G, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

210N

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64L, 91Y, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 189A, 192G, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

214E

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64L, 91Y, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 189A, 192G, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

217T

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64L, 91Y, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 189A, 192G, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

218E

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64L, 91Y, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 189A, 192G, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

221K

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64L, 91Y, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 189A, 192G, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

222K

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64L, 91Y, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 189A, 192G, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

235C

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64L, 91Y, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 189A, 192G, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

236D

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64L, 91Y, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 189A, 192G, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

237G

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64L, 91Y, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 189A, 192G, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

238D

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64L, 91Y, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 189A, 192G, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

239R

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64L, 91Y, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 189A, 192G, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

241Y

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64L, 91Y, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 189A, 192G, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

260Q

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64L, 91Y, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 189A, 192G, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

279R

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64L, 91Y, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 189A, 192G, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

281H

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64L, 91Y, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 189A, 192G, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

282R

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64L, 91Y, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 189A, 192G, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)
catalytic triad cd...

45E

catalytic triad
45E, 114K, 175C
CDD
cd07570 (GAT_Gln-NAD-synth)

114K

catalytic triad
45E, 114K, 175C
CDD
cd07570 (GAT_Gln-NAD-synth)

175C

catalytic triad
45E, 114K, 175C
CDD
cd07570 (GAT_Gln-NAD-synth)
active site cd07570

45E

active site
45E, 114K, 118A, 120D, 123Y, 125E, 175C, 176E, 179F, 208K
CDD
cd07570 (GAT_Gln-NAD-synth)

114K

active site
45E, 114K, 118A, 120D, 123Y, 125E, 175C, 176E, 179F, 208K
CDD
cd07570 (GAT_Gln-NAD-synth)

118A

active site
45E, 114K, 118A, 120D, 123Y, 125E, 175C, 176E, 179F, 208K
CDD
cd07570 (GAT_Gln-NAD-synth)

120D

active site
45E, 114K, 118A, 120D, 123Y, 125E, 175C, 176E, 179F, 208K
CDD
cd07570 (GAT_Gln-NAD-synth)

123Y

active site
45E, 114K, 118A, 120D, 123Y, 125E, 175C, 176E, 179F, 208K
CDD
cd07570 (GAT_Gln-NAD-synth)

125E

active site
45E, 114K, 118A, 120D, 123Y, 125E, 175C, 176E, 179F, 208K
CDD
cd07570 (GAT_Gln-NAD-synth)

175C

active site
45E, 114K, 118A, 120D, 123Y, 125E, 175C, 176E, 179F, 208K
CDD
cd07570 (GAT_Gln-NAD-synth)

176E

active site
45E, 114K, 118A, 120D, 123Y, 125E, 175C, 176E, 179F, 208K
CDD
cd07570 (GAT_Gln-NAD-synth)

179F

active site
45E, 114K, 118A, 120D, 123Y, 125E, 175C, 176E, 179F, 208K
CDD
cd07570 (GAT_Gln-NAD-synth)

208K

active site
45E, 114K, 118A, 120D, 123Y, 125E, 175C, 176E, 179F, 208K
CDD
cd07570 (GAT_Gln-NAD-synth)
protein interface ...

116W

protein interface 1
116W, 117M, 118A, 120D, 121G, 122N, 124R, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

117M

protein interface 1
116W, 117M, 118A, 120D, 121G, 122N, 124R, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

118A

protein interface 1
116W, 117M, 118A, 120D, 121G, 122N, 124R, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

120D

protein interface 1
116W, 117M, 118A, 120D, 121G, 122N, 124R, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

121G

protein interface 1
116W, 117M, 118A, 120D, 121G, 122N, 124R, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

122N

protein interface 1
116W, 117M, 118A, 120D, 121G, 122N, 124R, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

124R

protein interface 1
116W, 117M, 118A, 120D, 121G, 122N, 124R, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

133R

protein interface 1
116W, 117M, 118A, 120D, 121G, 122N, 124R, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

176E

protein interface 1
116W, 117M, 118A, 120D, 121G, 122N, 124R, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

178L

protein interface 1
116W, 117M, 118A, 120D, 121G, 122N, 124R, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

179F

protein interface 1
116W, 117M, 118A, 120D, 121G, 122N, 124R, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

180T

protein interface 1
116W, 117M, 118A, 120D, 121G, 122N, 124R, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

181P

protein interface 1
116W, 117M, 118A, 120D, 121G, 122N, 124R, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

182N

protein interface 1
116W, 117M, 118A, 120D, 121G, 122N, 124R, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

186I

protein interface 1
116W, 117M, 118A, 120D, 121G, 122N, 124R, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

187K

protein interface 1
116W, 117M, 118A, 120D, 121G, 122N, 124R, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

204H

protein interface 1
116W, 117M, 118A, 120D, 121G, 122N, 124R, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

205E

protein interface 1
116W, 117M, 118A, 120D, 121G, 122N, 124R, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

206L

protein interface 1
116W, 117M, 118A, 120D, 121G, 122N, 124R, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

207R

protein interface 1
116W, 117M, 118A, 120D, 121G, 122N, 124R, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

210N

protein interface 1
116W, 117M, 118A, 120D, 121G, 122N, 124R, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

214E

protein interface 1
116W, 117M, 118A, 120D, 121G, 122N, 124R, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

217T

protein interface 1
116W, 117M, 118A, 120D, 121G, 122N, 124R, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

218E

protein interface 1
116W, 117M, 118A, 120D, 121G, 122N, 124R, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

221K

protein interface 1
116W, 117M, 118A, 120D, 121G, 122N, 124R, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

222K

protein interface 1
116W, 117M, 118A, 120D, 121G, 122N, 124R, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

235C

protein interface 1
116W, 117M, 118A, 120D, 121G, 122N, 124R, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

237G

protein interface 1
116W, 117M, 118A, 120D, 121G, 122N, 124R, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

238D

protein interface 1
116W, 117M, 118A, 120D, 121G, 122N, 124R, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

239R

protein interface 1
116W, 117M, 118A, 120D, 121G, 122N, 124R, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

241Y

protein interface 1
116W, 117M, 118A, 120D, 121G, 122N, 124R, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

260Q

protein interface 1
116W, 117M, 118A, 120D, 121G, 122N, 124R, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

281H

protein interface 1
116W, 117M, 118A, 120D, 121G, 122N, 124R, 133R, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187K, 204H, 205E, 206L, 207R, 210N, 214E, 217T, 218E, 221K, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)
homodimer interfac...

340G

homodimer interface
340G, 341P, 344W, 347D, 348Y, 451Y, 452H, 453V, 454N, 457I, 458D, 471V, 472T, 490A, 494I, 497R, 498I, 500M, 501V, 502L, 504Y, 505M, 506F, 508Q, 509L, 541K, 542Y, 545S, 546S, 547A, 548D, 549I, 550N, 553G, 554G, 660H, 662M
CDD
cd00553 (NAD_synthase)

341P

homodimer interface
340G, 341P, 344W, 347D, 348Y, 451Y, 452H, 453V, 454N, 457I, 458D, 471V, 472T, 490A, 494I, 497R, 498I, 500M, 501V, 502L, 504Y, 505M, 506F, 508Q, 509L, 541K, 542Y, 545S, 546S, 547A, 548D, 549I, 550N, 553G, 554G, 660H, 662M
CDD
cd00553 (NAD_synthase)

344W

homodimer interface
340G, 341P, 344W, 347D, 348Y, 451Y, 452H, 453V, 454N, 457I, 458D, 471V, 472T, 490A, 494I, 497R, 498I, 500M, 501V, 502L, 504Y, 505M, 506F, 508Q, 509L, 541K, 542Y, 545S, 546S, 547A, 548D, 549I, 550N, 553G, 554G, 660H, 662M
CDD
cd00553 (NAD_synthase)

347D

homodimer interface
340G, 341P, 344W, 347D, 348Y, 451Y, 452H, 453V, 454N, 457I, 458D, 471V, 472T, 490A, 494I, 497R, 498I, 500M, 501V, 502L, 504Y, 505M, 506F, 508Q, 509L, 541K, 542Y, 545S, 546S, 547A, 548D, 549I, 550N, 553G, 554G, 660H, 662M
CDD
cd00553 (NAD_synthase)

348Y

homodimer interface
340G, 341P, 344W, 347D, 348Y, 451Y, 452H, 453V, 454N, 457I, 458D, 471V, 472T, 490A, 494I, 497R, 498I, 500M, 501V, 502L, 504Y, 505M, 506F, 508Q, 509L, 541K, 542Y, 545S, 546S, 547A, 548D, 549I, 550N, 553G, 554G, 660H, 662M
CDD
cd00553 (NAD_synthase)

451Y

homodimer interface
340G, 341P, 344W, 347D, 348Y, 451Y, 452H, 453V, 454N, 457I, 458D, 471V, 472T, 490A, 494I, 497R, 498I, 500M, 501V, 502L, 504Y, 505M, 506F, 508Q, 509L, 541K, 542Y, 545S, 546S, 547A, 548D, 549I, 550N, 553G, 554G, 660H, 662M
CDD
cd00553 (NAD_synthase)

452H

homodimer interface
340G, 341P, 344W, 347D, 348Y, 451Y, 452H, 453V, 454N, 457I, 458D, 471V, 472T, 490A, 494I, 497R, 498I, 500M, 501V, 502L, 504Y, 505M, 506F, 508Q, 509L, 541K, 542Y, 545S, 546S, 547A, 548D, 549I, 550N, 553G, 554G, 660H, 662M
CDD
cd00553 (NAD_synthase)

453V

homodimer interface
340G, 341P, 344W, 347D, 348Y, 451Y, 452H, 453V, 454N, 457I, 458D, 471V, 472T, 490A, 494I, 497R, 498I, 500M, 501V, 502L, 504Y, 505M, 506F, 508Q, 509L, 541K, 542Y, 545S, 546S, 547A, 548D, 549I, 550N, 553G, 554G, 660H, 662M
CDD
cd00553 (NAD_synthase)

454N

homodimer interface
340G, 341P, 344W, 347D, 348Y, 451Y, 452H, 453V, 454N, 457I, 458D, 471V, 472T, 490A, 494I, 497R, 498I, 500M, 501V, 502L, 504Y, 505M, 506F, 508Q, 509L, 541K, 542Y, 545S, 546S, 547A, 548D, 549I, 550N, 553G, 554G, 660H, 662M
CDD
cd00553 (NAD_synthase)

457I

homodimer interface
340G, 341P, 344W, 347D, 348Y, 451Y, 452H, 453V, 454N, 457I, 458D, 471V, 472T, 490A, 494I, 497R, 498I, 500M, 501V, 502L, 504Y, 505M, 506F, 508Q, 509L, 541K, 542Y, 545S, 546S, 547A, 548D, 549I, 550N, 553G, 554G, 660H, 662M
CDD
cd00553 (NAD_synthase)

458D

homodimer interface
340G, 341P, 344W, 347D, 348Y, 451Y, 452H, 453V, 454N, 457I, 458D, 471V, 472T, 490A, 494I, 497R, 498I, 500M, 501V, 502L, 504Y, 505M, 506F, 508Q, 509L, 541K, 542Y, 545S, 546S, 547A, 548D, 549I, 550N, 553G, 554G, 660H, 662M
CDD
cd00553 (NAD_synthase)

471V

homodimer interface
340G, 341P, 344W, 347D, 348Y, 451Y, 452H, 453V, 454N, 457I, 458D, 471V, 472T, 490A, 494I, 497R, 498I, 500M, 501V, 502L, 504Y, 505M, 506F, 508Q, 509L, 541K, 542Y, 545S, 546S, 547A, 548D, 549I, 550N, 553G, 554G, 660H, 662M
CDD
cd00553 (NAD_synthase)

472T

homodimer interface
340G, 341P, 344W, 347D, 348Y, 451Y, 452H, 453V, 454N, 457I, 458D, 471V, 472T, 490A, 494I, 497R, 498I, 500M, 501V, 502L, 504Y, 505M, 506F, 508Q, 509L, 541K, 542Y, 545S, 546S, 547A, 548D, 549I, 550N, 553G, 554G, 660H, 662M
CDD
cd00553 (NAD_synthase)

490A

homodimer interface
340G, 341P, 344W, 347D, 348Y, 451Y, 452H, 453V, 454N, 457I, 458D, 471V, 472T, 490A, 494I, 497R, 498I, 500M, 501V, 502L, 504Y, 505M, 506F, 508Q, 509L, 541K, 542Y, 545S, 546S, 547A, 548D, 549I, 550N, 553G, 554G, 660H, 662M
CDD
cd00553 (NAD_synthase)

494I

homodimer interface
340G, 341P, 344W, 347D, 348Y, 451Y, 452H, 453V, 454N, 457I, 458D, 471V, 472T, 490A, 494I, 497R, 498I, 500M, 501V, 502L, 504Y, 505M, 506F, 508Q, 509L, 541K, 542Y, 545S, 546S, 547A, 548D, 549I, 550N, 553G, 554G, 660H, 662M
CDD
cd00553 (NAD_synthase)

497R

homodimer interface
340G, 341P, 344W, 347D, 348Y, 451Y, 452H, 453V, 454N, 457I, 458D, 471V, 472T, 490A, 494I, 497R, 498I, 500M, 501V, 502L, 504Y, 505M, 506F, 508Q, 509L, 541K, 542Y, 545S, 546S, 547A, 548D, 549I, 550N, 553G, 554G, 660H, 662M
CDD
cd00553 (NAD_synthase)

498I

homodimer interface
340G, 341P, 344W, 347D, 348Y, 451Y, 452H, 453V, 454N, 457I, 458D, 471V, 472T, 490A, 494I, 497R, 498I, 500M, 501V, 502L, 504Y, 505M, 506F, 508Q, 509L, 541K, 542Y, 545S, 546S, 547A, 548D, 549I, 550N, 553G, 554G, 660H, 662M
CDD
cd00553 (NAD_synthase)

500M

homodimer interface
340G, 341P, 344W, 347D, 348Y, 451Y, 452H, 453V, 454N, 457I, 458D, 471V, 472T, 490A, 494I, 497R, 498I, 500M, 501V, 502L, 504Y, 505M, 506F, 508Q, 509L, 541K, 542Y, 545S, 546S, 547A, 548D, 549I, 550N, 553G, 554G, 660H, 662M
CDD
cd00553 (NAD_synthase)

501V

homodimer interface
340G, 341P, 344W, 347D, 348Y, 451Y, 452H, 453V, 454N, 457I, 458D, 471V, 472T, 490A, 494I, 497R, 498I, 500M, 501V, 502L, 504Y, 505M, 506F, 508Q, 509L, 541K, 542Y, 545S, 546S, 547A, 548D, 549I, 550N, 553G, 554G, 660H, 662M
CDD
cd00553 (NAD_synthase)

502L

homodimer interface
340G, 341P, 344W, 347D, 348Y, 451Y, 452H, 453V, 454N, 457I, 458D, 471V, 472T, 490A, 494I, 497R, 498I, 500M, 501V, 502L, 504Y, 505M, 506F, 508Q, 509L, 541K, 542Y, 545S, 546S, 547A, 548D, 549I, 550N, 553G, 554G, 660H, 662M
CDD
cd00553 (NAD_synthase)

504Y

homodimer interface
340G, 341P, 344W, 347D, 348Y, 451Y, 452H, 453V, 454N, 457I, 458D, 471V, 472T, 490A, 494I, 497R, 498I, 500M, 501V, 502L, 504Y, 505M, 506F, 508Q, 509L, 541K, 542Y, 545S, 546S, 547A, 548D, 549I, 550N, 553G, 554G, 660H, 662M
CDD
cd00553 (NAD_synthase)

505M

homodimer interface
340G, 341P, 344W, 347D, 348Y, 451Y, 452H, 453V, 454N, 457I, 458D, 471V, 472T, 490A, 494I, 497R, 498I, 500M, 501V, 502L, 504Y, 505M, 506F, 508Q, 509L, 541K, 542Y, 545S, 546S, 547A, 548D, 549I, 550N, 553G, 554G, 660H, 662M
CDD
cd00553 (NAD_synthase)

506F

homodimer interface
340G, 341P, 344W, 347D, 348Y, 451Y, 452H, 453V, 454N, 457I, 458D, 471V, 472T, 490A, 494I, 497R, 498I, 500M, 501V, 502L, 504Y, 505M, 506F, 508Q, 509L, 541K, 542Y, 545S, 546S, 547A, 548D, 549I, 550N, 553G, 554G, 660H, 662M
CDD
cd00553 (NAD_synthase)

508Q

homodimer interface
340G, 341P, 344W, 347D, 348Y, 451Y, 452H, 453V, 454N, 457I, 458D, 471V, 472T, 490A, 494I, 497R, 498I, 500M, 501V, 502L, 504Y, 505M, 506F, 508Q, 509L, 541K, 542Y, 545S, 546S, 547A, 548D, 549I, 550N, 553G, 554G, 660H, 662M
CDD
cd00553 (NAD_synthase)

509L

homodimer interface
340G, 341P, 344W, 347D, 348Y, 451Y, 452H, 453V, 454N, 457I, 458D, 471V, 472T, 490A, 494I, 497R, 498I, 500M, 501V, 502L, 504Y, 505M, 506F, 508Q, 509L, 541K, 542Y, 545S, 546S, 547A, 548D, 549I, 550N, 553G, 554G, 660H, 662M
CDD
cd00553 (NAD_synthase)

541K

homodimer interface
340G, 341P, 344W, 347D, 348Y, 451Y, 452H, 453V, 454N, 457I, 458D, 471V, 472T, 490A, 494I, 497R, 498I, 500M, 501V, 502L, 504Y, 505M, 506F, 508Q, 509L, 541K, 542Y, 545S, 546S, 547A, 548D, 549I, 550N, 553G, 554G, 660H, 662M
CDD
cd00553 (NAD_synthase)

542Y

homodimer interface
340G, 341P, 344W, 347D, 348Y, 451Y, 452H, 453V, 454N, 457I, 458D, 471V, 472T, 490A, 494I, 497R, 498I, 500M, 501V, 502L, 504Y, 505M, 506F, 508Q, 509L, 541K, 542Y, 545S, 546S, 547A, 548D, 549I, 550N, 553G, 554G, 660H, 662M
CDD
cd00553 (NAD_synthase)

545S

homodimer interface
340G, 341P, 344W, 347D, 348Y, 451Y, 452H, 453V, 454N, 457I, 458D, 471V, 472T, 490A, 494I, 497R, 498I, 500M, 501V, 502L, 504Y, 505M, 506F, 508Q, 509L, 541K, 542Y, 545S, 546S, 547A, 548D, 549I, 550N, 553G, 554G, 660H, 662M
CDD
cd00553 (NAD_synthase)

546S

homodimer interface
340G, 341P, 344W, 347D, 348Y, 451Y, 452H, 453V, 454N, 457I, 458D, 471V, 472T, 490A, 494I, 497R, 498I, 500M, 501V, 502L, 504Y, 505M, 506F, 508Q, 509L, 541K, 542Y, 545S, 546S, 547A, 548D, 549I, 550N, 553G, 554G, 660H, 662M
CDD
cd00553 (NAD_synthase)

547A

homodimer interface
340G, 341P, 344W, 347D, 348Y, 451Y, 452H, 453V, 454N, 457I, 458D, 471V, 472T, 490A, 494I, 497R, 498I, 500M, 501V, 502L, 504Y, 505M, 506F, 508Q, 509L, 541K, 542Y, 545S, 546S, 547A, 548D, 549I, 550N, 553G, 554G, 660H, 662M
CDD
cd00553 (NAD_synthase)

548D

homodimer interface
340G, 341P, 344W, 347D, 348Y, 451Y, 452H, 453V, 454N, 457I, 458D, 471V, 472T, 490A, 494I, 497R, 498I, 500M, 501V, 502L, 504Y, 505M, 506F, 508Q, 509L, 541K, 542Y, 545S, 546S, 547A, 548D, 549I, 550N, 553G, 554G, 660H, 662M
CDD
cd00553 (NAD_synthase)

549I

homodimer interface
340G, 341P, 344W, 347D, 348Y, 451Y, 452H, 453V, 454N, 457I, 458D, 471V, 472T, 490A, 494I, 497R, 498I, 500M, 501V, 502L, 504Y, 505M, 506F, 508Q, 509L, 541K, 542Y, 545S, 546S, 547A, 548D, 549I, 550N, 553G, 554G, 660H, 662M
CDD
cd00553 (NAD_synthase)

550N

homodimer interface
340G, 341P, 344W, 347D, 348Y, 451Y, 452H, 453V, 454N, 457I, 458D, 471V, 472T, 490A, 494I, 497R, 498I, 500M, 501V, 502L, 504Y, 505M, 506F, 508Q, 509L, 541K, 542Y, 545S, 546S, 547A, 548D, 549I, 550N, 553G, 554G, 660H, 662M
CDD
cd00553 (NAD_synthase)

553G

homodimer interface
340G, 341P, 344W, 347D, 348Y, 451Y, 452H, 453V, 454N, 457I, 458D, 471V, 472T, 490A, 494I, 497R, 498I, 500M, 501V, 502L, 504Y, 505M, 506F, 508Q, 509L, 541K, 542Y, 545S, 546S, 547A, 548D, 549I, 550N, 553G, 554G, 660H, 662M
CDD
cd00553 (NAD_synthase)

554G

homodimer interface
340G, 341P, 344W, 347D, 348Y, 451Y, 452H, 453V, 454N, 457I, 458D, 471V, 472T, 490A, 494I, 497R, 498I, 500M, 501V, 502L, 504Y, 505M, 506F, 508Q, 509L, 541K, 542Y, 545S, 546S, 547A, 548D, 549I, 550N, 553G, 554G, 660H, 662M
CDD
cd00553 (NAD_synthase)

660H

homodimer interface
340G, 341P, 344W, 347D, 348Y, 451Y, 452H, 453V, 454N, 457I, 458D, 471V, 472T, 490A, 494I, 497R, 498I, 500M, 501V, 502L, 504Y, 505M, 506F, 508Q, 509L, 541K, 542Y, 545S, 546S, 547A, 548D, 549I, 550N, 553G, 554G, 660H, 662M
CDD
cd00553 (NAD_synthase)

662M

homodimer interface
340G, 341P, 344W, 347D, 348Y, 451Y, 452H, 453V, 454N, 457I, 458D, 471V, 472T, 490A, 494I, 497R, 498I, 500M, 501V, 502L, 504Y, 505M, 506F, 508Q, 509L, 541K, 542Y, 545S, 546S, 547A, 548D, 549I, 550N, 553G, 554G, 660H, 662M
CDD
cd00553 (NAD_synthase)
NAD binding pocket...

359I

NAD binding pocket
359I, 360P, 361L, 362S, 367S, 426C, 427Y, 428M, 489L, 493N, 496A, 497R, 499R, 528S, 533E, 538Y, 539L, 540T, 541K, 544C, 585T, 586A, 588L, 602D, 660H, 661K
CDD
cd00553 (NAD_synthase)

360P

NAD binding pocket
359I, 360P, 361L, 362S, 367S, 426C, 427Y, 428M, 489L, 493N, 496A, 497R, 499R, 528S, 533E, 538Y, 539L, 540T, 541K, 544C, 585T, 586A, 588L, 602D, 660H, 661K
CDD
cd00553 (NAD_synthase)

361L

NAD binding pocket
359I, 360P, 361L, 362S, 367S, 426C, 427Y, 428M, 489L, 493N, 496A, 497R, 499R, 528S, 533E, 538Y, 539L, 540T, 541K, 544C, 585T, 586A, 588L, 602D, 660H, 661K
CDD
cd00553 (NAD_synthase)

362S

NAD binding pocket
359I, 360P, 361L, 362S, 367S, 426C, 427Y, 428M, 489L, 493N, 496A, 497R, 499R, 528S, 533E, 538Y, 539L, 540T, 541K, 544C, 585T, 586A, 588L, 602D, 660H, 661K
CDD
cd00553 (NAD_synthase)

367S

NAD binding pocket
359I, 360P, 361L, 362S, 367S, 426C, 427Y, 428M, 489L, 493N, 496A, 497R, 499R, 528S, 533E, 538Y, 539L, 540T, 541K, 544C, 585T, 586A, 588L, 602D, 660H, 661K
CDD
cd00553 (NAD_synthase)

426C

NAD binding pocket
359I, 360P, 361L, 362S, 367S, 426C, 427Y, 428M, 489L, 493N, 496A, 497R, 499R, 528S, 533E, 538Y, 539L, 540T, 541K, 544C, 585T, 586A, 588L, 602D, 660H, 661K
CDD
cd00553 (NAD_synthase)

427Y

NAD binding pocket
359I, 360P, 361L, 362S, 367S, 426C, 427Y, 428M, 489L, 493N, 496A, 497R, 499R, 528S, 533E, 538Y, 539L, 540T, 541K, 544C, 585T, 586A, 588L, 602D, 660H, 661K
CDD
cd00553 (NAD_synthase)

428M

NAD binding pocket
359I, 360P, 361L, 362S, 367S, 426C, 427Y, 428M, 489L, 493N, 496A, 497R, 499R, 528S, 533E, 538Y, 539L, 540T, 541K, 544C, 585T, 586A, 588L, 602D, 660H, 661K
CDD
cd00553 (NAD_synthase)

489L

NAD binding pocket
359I, 360P, 361L, 362S, 367S, 426C, 427Y, 428M, 489L, 493N, 496A, 497R, 499R, 528S, 533E, 538Y, 539L, 540T, 541K, 544C, 585T, 586A, 588L, 602D, 660H, 661K
CDD
cd00553 (NAD_synthase)

493N

NAD binding pocket
359I, 360P, 361L, 362S, 367S, 426C, 427Y, 428M, 489L, 493N, 496A, 497R, 499R, 528S, 533E, 538Y, 539L, 540T, 541K, 544C, 585T, 586A, 588L, 602D, 660H, 661K
CDD
cd00553 (NAD_synthase)

496A

NAD binding pocket
359I, 360P, 361L, 362S, 367S, 426C, 427Y, 428M, 489L, 493N, 496A, 497R, 499R, 528S, 533E, 538Y, 539L, 540T, 541K, 544C, 585T, 586A, 588L, 602D, 660H, 661K
CDD
cd00553 (NAD_synthase)

497R

NAD binding pocket
359I, 360P, 361L, 362S, 367S, 426C, 427Y, 428M, 489L, 493N, 496A, 497R, 499R, 528S, 533E, 538Y, 539L, 540T, 541K, 544C, 585T, 586A, 588L, 602D, 660H, 661K
CDD
cd00553 (NAD_synthase)

499R

NAD binding pocket
359I, 360P, 361L, 362S, 367S, 426C, 427Y, 428M, 489L, 493N, 496A, 497R, 499R, 528S, 533E, 538Y, 539L, 540T, 541K, 544C, 585T, 586A, 588L, 602D, 660H, 661K
CDD
cd00553 (NAD_synthase)

528S

NAD binding pocket
359I, 360P, 361L, 362S, 367S, 426C, 427Y, 428M, 489L, 493N, 496A, 497R, 499R, 528S, 533E, 538Y, 539L, 540T, 541K, 544C, 585T, 586A, 588L, 602D, 660H, 661K
CDD
cd00553 (NAD_synthase)

533E

NAD binding pocket
359I, 360P, 361L, 362S, 367S, 426C, 427Y, 428M, 489L, 493N, 496A, 497R, 499R, 528S, 533E, 538Y, 539L, 540T, 541K, 544C, 585T, 586A, 588L, 602D, 660H, 661K
CDD
cd00553 (NAD_synthase)

538Y

NAD binding pocket
359I, 360P, 361L, 362S, 367S, 426C, 427Y, 428M, 489L, 493N, 496A, 497R, 499R, 528S, 533E, 538Y, 539L, 540T, 541K, 544C, 585T, 586A, 588L, 602D, 660H, 661K
CDD
cd00553 (NAD_synthase)

539L

NAD binding pocket
359I, 360P, 361L, 362S, 367S, 426C, 427Y, 428M, 489L, 493N, 496A, 497R, 499R, 528S, 533E, 538Y, 539L, 540T, 541K, 544C, 585T, 586A, 588L, 602D, 660H, 661K
CDD
cd00553 (NAD_synthase)

540T

NAD binding pocket
359I, 360P, 361L, 362S, 367S, 426C, 427Y, 428M, 489L, 493N, 496A, 497R, 499R, 528S, 533E, 538Y, 539L, 540T, 541K, 544C, 585T, 586A, 588L, 602D, 660H, 661K
CDD
cd00553 (NAD_synthase)

541K

NAD binding pocket
359I, 360P, 361L, 362S, 367S, 426C, 427Y, 428M, 489L, 493N, 496A, 497R, 499R, 528S, 533E, 538Y, 539L, 540T, 541K, 544C, 585T, 586A, 588L, 602D, 660H, 661K
CDD
cd00553 (NAD_synthase)

544C

NAD binding pocket
359I, 360P, 361L, 362S, 367S, 426C, 427Y, 428M, 489L, 493N, 496A, 497R, 499R, 528S, 533E, 538Y, 539L, 540T, 541K, 544C, 585T, 586A, 588L, 602D, 660H, 661K
CDD
cd00553 (NAD_synthase)

585T

NAD binding pocket
359I, 360P, 361L, 362S, 367S, 426C, 427Y, 428M, 489L, 493N, 496A, 497R, 499R, 528S, 533E, 538Y, 539L, 540T, 541K, 544C, 585T, 586A, 588L, 602D, 660H, 661K
CDD
cd00553 (NAD_synthase)

586A

NAD binding pocket
359I, 360P, 361L, 362S, 367S, 426C, 427Y, 428M, 489L, 493N, 496A, 497R, 499R, 528S, 533E, 538Y, 539L, 540T, 541K, 544C, 585T, 586A, 588L, 602D, 660H, 661K
CDD
cd00553 (NAD_synthase)

588L

NAD binding pocket
359I, 360P, 361L, 362S, 367S, 426C, 427Y, 428M, 489L, 493N, 496A, 497R, 499R, 528S, 533E, 538Y, 539L, 540T, 541K, 544C, 585T, 586A, 588L, 602D, 660H, 661K
CDD
cd00553 (NAD_synthase)

602D

NAD binding pocket
359I, 360P, 361L, 362S, 367S, 426C, 427Y, 428M, 489L, 493N, 496A, 497R, 499R, 528S, 533E, 538Y, 539L, 540T, 541K, 544C, 585T, 586A, 588L, 602D, 660H, 661K
CDD
cd00553 (NAD_synthase)

660H

NAD binding pocket
359I, 360P, 361L, 362S, 367S, 426C, 427Y, 428M, 489L, 493N, 496A, 497R, 499R, 528S, 533E, 538Y, 539L, 540T, 541K, 544C, 585T, 586A, 588L, 602D, 660H, 661K
CDD
cd00553 (NAD_synthase)

661K

NAD binding pocket
359I, 360P, 361L, 362S, 367S, 426C, 427Y, 428M, 489L, 493N, 496A, 497R, 499R, 528S, 533E, 538Y, 539L, 540T, 541K, 544C, 585T, 586A, 588L, 602D, 660H, 661K
CDD
cd00553 (NAD_synthase)
ATP binding pocket...

360P

ATP binding pocket
360P, 361L, 362S, 366D, 367S, 427Y, 428M, 499R, 528S, 557K, 584P, 585T
CDD
cd00553 (NAD_synthase)

361L

ATP binding pocket
360P, 361L, 362S, 366D, 367S, 427Y, 428M, 499R, 528S, 557K, 584P, 585T
CDD
cd00553 (NAD_synthase)

362S

ATP binding pocket
360P, 361L, 362S, 366D, 367S, 427Y, 428M, 499R, 528S, 557K, 584P, 585T
CDD
cd00553 (NAD_synthase)

366D

ATP binding pocket
360P, 361L, 362S, 366D, 367S, 427Y, 428M, 499R, 528S, 557K, 584P, 585T
CDD
cd00553 (NAD_synthase)

367S

ATP binding pocket
360P, 361L, 362S, 366D, 367S, 427Y, 428M, 499R, 528S, 557K, 584P, 585T
CDD
cd00553 (NAD_synthase)

427Y

ATP binding pocket
360P, 361L, 362S, 366D, 367S, 427Y, 428M, 499R, 528S, 557K, 584P, 585T
CDD
cd00553 (NAD_synthase)

428M

ATP binding pocket
360P, 361L, 362S, 366D, 367S, 427Y, 428M, 499R, 528S, 557K, 584P, 585T
CDD
cd00553 (NAD_synthase)

499R

ATP binding pocket
360P, 361L, 362S, 366D, 367S, 427Y, 428M, 499R, 528S, 557K, 584P, 585T
CDD
cd00553 (NAD_synthase)

528S

ATP binding pocket
360P, 361L, 362S, 366D, 367S, 427Y, 428M, 499R, 528S, 557K, 584P, 585T
CDD
cd00553 (NAD_synthase)

557K

ATP binding pocket
360P, 361L, 362S, 366D, 367S, 427Y, 428M, 499R, 528S, 557K, 584P, 585T
CDD
cd00553 (NAD_synthase)

584P

ATP binding pocket
360P, 361L, 362S, 366D, 367S, 427Y, 428M, 499R, 528S, 557K, 584P, 585T
CDD
cd00553 (NAD_synthase)

585T

ATP binding pocket
360P, 361L, 362S, 366D, 367S, 427Y, 428M, 499R, 528S, 557K, 584P, 585T
CDD
cd00553 (NAD_synthase)
Mg binding site cd...

362S

Mg binding site
362S, 366D, 533E, 585T
CDD
cd00553 (NAD_synthase)

366D

Mg binding site
362S, 366D, 533E, 585T
CDD
cd00553 (NAD_synthase)

533E

Mg binding site
362S, 366D, 533E, 585T
CDD
cd00553 (NAD_synthase)

585T

Mg binding site
362S, 366D, 533E, 585T
CDD
cd00553 (NAD_synthase)
active-site loop c...

435Q

active-site loop
435Q, 581T, 582A, 583T, 584P, 585T, 586A, 587E, 588L, 596V, 597Q, 598S, 599D, 600E, 601A, 602D, 603M
CDD
cd00553 (NAD_synthase)

581T

active-site loop
435Q, 581T, 582A, 583T, 584P, 585T, 586A, 587E, 588L, 596V, 597Q, 598S, 599D, 600E, 601A, 602D, 603M
CDD
cd00553 (NAD_synthase)

582A

active-site loop
435Q, 581T, 582A, 583T, 584P, 585T, 586A, 587E, 588L, 596V, 597Q, 598S, 599D, 600E, 601A, 602D, 603M
CDD
cd00553 (NAD_synthase)

583T

active-site loop
435Q, 581T, 582A, 583T, 584P, 585T, 586A, 587E, 588L, 596V, 597Q, 598S, 599D, 600E, 601A, 602D, 603M
CDD
cd00553 (NAD_synthase)

584P

active-site loop
435Q, 581T, 582A, 583T, 584P, 585T, 586A, 587E, 588L, 596V, 597Q, 598S, 599D, 600E, 601A, 602D, 603M
CDD
cd00553 (NAD_synthase)

585T

active-site loop
435Q, 581T, 582A, 583T, 584P, 585T, 586A, 587E, 588L, 596V, 597Q, 598S, 599D, 600E, 601A, 602D, 603M
CDD
cd00553 (NAD_synthase)

586A

active-site loop
435Q, 581T, 582A, 583T, 584P, 585T, 586A, 587E, 588L, 596V, 597Q, 598S, 599D, 600E, 601A, 602D, 603M
CDD
cd00553 (NAD_synthase)

587E

active-site loop
435Q, 581T, 582A, 583T, 584P, 585T, 586A, 587E, 588L, 596V, 597Q, 598S, 599D, 600E, 601A, 602D, 603M
CDD
cd00553 (NAD_synthase)

588L

active-site loop
435Q, 581T, 582A, 583T, 584P, 585T, 586A, 587E, 588L, 596V, 597Q, 598S, 599D, 600E, 601A, 602D, 603M
CDD
cd00553 (NAD_synthase)

596V

active-site loop
435Q, 581T, 582A, 583T, 584P, 585T, 586A, 587E, 588L, 596V, 597Q, 598S, 599D, 600E, 601A, 602D, 603M
CDD
cd00553 (NAD_synthase)

597Q

active-site loop
435Q, 581T, 582A, 583T, 584P, 585T, 586A, 587E, 588L, 596V, 597Q, 598S, 599D, 600E, 601A, 602D, 603M
CDD
cd00553 (NAD_synthase)

598S

active-site loop
435Q, 581T, 582A, 583T, 584P, 585T, 586A, 587E, 588L, 596V, 597Q, 598S, 599D, 600E, 601A, 602D, 603M
CDD
cd00553 (NAD_synthase)

599D

active-site loop
435Q, 581T, 582A, 583T, 584P, 585T, 586A, 587E, 588L, 596V, 597Q, 598S, 599D, 600E, 601A, 602D, 603M
CDD
cd00553 (NAD_synthase)

600E

active-site loop
435Q, 581T, 582A, 583T, 584P, 585T, 586A, 587E, 588L, 596V, 597Q, 598S, 599D, 600E, 601A, 602D, 603M
CDD
cd00553 (NAD_synthase)

601A

active-site loop
435Q, 581T, 582A, 583T, 584P, 585T, 586A, 587E, 588L, 596V, 597Q, 598S, 599D, 600E, 601A, 602D, 603M
CDD
cd00553 (NAD_synthase)

602D

active-site loop
435Q, 581T, 582A, 583T, 584P, 585T, 586A, 587E, 588L, 596V, 597Q, 598S, 599D, 600E, 601A, 602D, 603M
CDD
cd00553 (NAD_synthase)

603M

active-site loop
435Q, 581T, 582A, 583T, 584P, 585T, 586A, 587E, 588L, 596V, 597Q, 598S, 599D, 600E, 601A, 602D, 603M
CDD
cd00553 (NAD_synthase)

Protein sequence

>MIA_00798_1
MVHLVTLATCNLNQWALDFEGNRDRIIESIRQAKAQGAIFRTGPELEITGYGCLDHFLEPDLYLHAWEVYRDILTCPEAQ
DMLIDVGMPVYHKNIRYNCRVVAYNKEILLIRPKLWMANDGNYRELRYFTPWRGLNSSEDYFLPRIIRDVTKQTIVPFGD
VCLRSNYTYFGFETCEELFTPNSPHIKMALGGVEIFTNSSGSHHELRKLNTRLELITEATKKCGGVYLYSNQRGCDGDRL
YYDGCALIVVNGEVVAQAAQFGLKDVETIVATVDLDTVRSHRSSPSFGMQSQNTPEASLNTVVKYSAFSDGTDLDYDPTI
VPTPTRPIRYHSPEEEIALGPACWLWDYLRRCRAAGFFIPLSGGIDSCATSVIVHSMCRLVAKEAKEGNEQVIKDARRLA
RVSDESEPDYLPTDPVEFCSRIFHTCYMGSENSSQETRDRARDLAKAIGSYHVNFNIDTVTTAIRVLFTTVTGHTPRFKM
FGGTPTENLALQNIQARIRMVLAYMFAQLLPWVRFGGNAPGGLLVLGSANVDESLRGYLTKYDCSSADINPIGGISKHDL
KKFIAYARDAFELPILEEFLTATPTAELEPITEDYVQSDEADMGMTYDELSVFGRLRKVKKCGPYSMFLSLLHEWSPRLT
PAEIAVKVKRFFYFYAINRHKMTTITPAYHAEQYSPDDNRFDLRPFLILPGFPWAAKKIDEVVKRYSETKQD

GO term prediction

Biological Process

GO:0006807 nitrogen compound metabolic process
GO:0009435 NAD biosynthetic process

Molecular Function

GO:0003952 NAD+ synthase (glutamine-hydrolyzing) activity
GO:0005524 ATP binding
GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds

Cellular Component

None predicted.

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Entry type

Status

Per-residue features