MCA_04885_1

Protein

Length

713 amino acids

Gene name: QNS1

Description: Glutamine-dependent NAD(+) synthetase

Browser: contigC:4339573-4341715-

RNA-seq: read pairs 4184, FPKM 72.4, percentile rank 73.4% (100% = highest expression)

Protein function

Annotation:		QNS1	Glutamine-dependent NAD(+) synthetase
KEGG:	K01950	E6.3.5.1	NAD+ synthase (glutamine-hydrolysing) [EC:6.3.5.1]
EGGNOG:	0PGZM	QNS1	glutamine-dependent NAD( ) synthetase
SGD closest match:	S000001116	QNS1	Glutamine-dependent NAD(+) synthetase
CGD closest match:	CAL0000191648	orf19.1460	Glutamine-dependent NAD(+) synthetase

Protein alignments

	%id	Aln length
MIA_00798_1	80.65%	708	MIA_00798_1
A0A0J9XFX9_GEOCN	74.54%	699	Glutamine-dependent NAD(+) synthetase OS=Geotrichum candidum GN=BN980_GECA15s01462g PE=3 SV=1
A0A161HMU7_9ASCO	72.68%	710	Glutamine-dependent NAD(+) synthetase OS=Sugiyamaella lignohabitans GN=QNS1 PE=3 SV=1
A0A1E3PR42_9ASCO	70.92%	705	Glutamine-dependent NAD(+) synthetase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_48389 PE=3 SV=1
A0A060TI09_BLAAD	71.10%	706	Glutamine-dependent NAD(+) synthetase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D35442g PE=3 SV=1
A0A1E4TB50_9ASCO	68.86%	700	Glutamine-dependent NAD(+) synthetase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_132553 PE=3 SV=1
Q6CGE0_YARLI	69.09%	702	Glutamine-dependent NAD(+) synthetase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_A20108g PE=3 SV=1
NADE_YEAST	66.57%	706	Glutamine-dependent NAD(+) synthetase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=QNS1 PE=1 SV=1
UniRef50_P38795	66.57%	706	Glutamine-dependent NAD(+) synthetase n=584 Tax=cellular organisms TaxID=131567 RepID=NADE_YEAST
Q5ALW6_CANAL	65.95%	702	Glutamine-dependent NAD(+) synthetase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.1460 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1176

Protein family membership

NAD(+) synthetase (IPR003694)
- Glutamine-dependent NAD(+) synthetase (IPR014445)

Domains and repeats

Domain
2 - 301
Carbon-nitrogen hydrolase (IPR003010)
333 - 680
Rossmann-like alpha/beta/alpha sandwich fold (IPR014729)
NAD/GMP synthase (IPR022310)

1 100 200 300 400 500 600 713

Detailed signature matches

IPR003694

NAD(+) synthetase
1. TIGR00552
  
  420 - 605
  
  TIGRFAMs
  TIGR00552 (TIGR00552)
2. cd00553 (NAD_synthase)
  
  331 - 657
  
  CDD
  cd00553 (NAD_synthase)
IPR014445

Glutamine-dependent NAD(+) synthetase
1. PIRSF006630 (NADS_GAT)
  
  2 - 690
  
  PIRSF
  PIRSF006630 (NADS_GAT)
IPR003010

Carbon-nitrogen hydrolase
1. G3DSA:3.60.11...
  
  2 - 287
  
  GENE3D
  G3DSA:3.60.110.10 (G3DSA:3.60.110.10)
2. PS50263 (CN_HYDROLASE)
  
  5 - 301
  
  PROSITE profiles
  PS50263 (CN_HYDROLASE)
3. PF00795 (CN_hydrolase)
  
  7 - 282
  
  Pfam
  PF00795 (CN_hydrolase)
4. SSF56317 (Carbon-ni...)
  
  4 - 286
  
  SUPERFAMILY
  SSF56317 (Carbon-nitrogen hydrolase)
IPR014729

Rossmann-like alpha/beta/alpha sandwich fold
1. G3DSA:3.40.50...
  
  333 - 680
  
  GENE3D
  G3DSA:3.40.50.620 (G3DSA:3.40.50.620)
IPR022310

NAD/GMP synthase
1. PF02540 (NAD_synthase)
  
  342 - 604
  
  Pfam
  PF02540 (NAD_synthase)

no IPR

Unintegrated signatures

NON_CYTOPLASM... (N...)

17 - 713

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)
SIGNAL_PEPTIDE (Sig...)

1 - 16

PHOBIUS
SIGNAL_PEPTIDE (Signal Peptide)
SIGNAL_PEPTID... (S...)

13 - 16

PHOBIUS
SIGNAL_PEPTIDE_C_REGION (Signal peptide C-region)
SIGNAL_PEPTID... (S...)

4 - 12

PHOBIUS
SIGNAL_PEPTIDE_H_REGION (Signal peptide H-region)
SIGNAL_PEPTID... (S...)

1 - 3

PHOBIUS
SIGNAL_PEPTIDE_N_REGION (Signal peptide N-region)
SSF52402 (Adenine n...)

322 - 381

SUPERFAMILY
SSF52402 (Adenine nucleotide alpha hydrolases-like)

411 - 669

SUPERFAMILY
SSF52402 (Adenine nucleotide alpha hydrolases-like)
cd07570 (GAT_Gln-NA...)

6 - 286

CDD
cd07570 (GAT_Gln-NAD-synth)

Residue annotation

multimer interface...

16S

multimer interface
16S, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64E, 91I, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 189A, 192G, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

17L

multimer interface
16S, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64E, 91I, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 189A, 192G, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

18D

multimer interface
16S, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64E, 91I, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 189A, 192G, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

19F

multimer interface
16S, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64E, 91I, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 189A, 192G, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

20E

multimer interface
16S, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64E, 91I, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 189A, 192G, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

53C

multimer interface
16S, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64E, 91I, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 189A, 192G, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

54L

multimer interface
16S, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64E, 91I, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 189A, 192G, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

55D

multimer interface
16S, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64E, 91I, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 189A, 192G, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

56H

multimer interface
16S, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64E, 91I, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 189A, 192G, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

58L

multimer interface
16S, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64E, 91I, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 189A, 192G, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

59E

multimer interface
16S, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64E, 91I, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 189A, 192G, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

60P

multimer interface
16S, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64E, 91I, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 189A, 192G, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

61D

multimer interface
16S, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64E, 91I, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 189A, 192G, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

64E

multimer interface
16S, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64E, 91I, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 189A, 192G, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

91I

multimer interface
16S, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64E, 91I, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 189A, 192G, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

96R

multimer interface
16S, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64E, 91I, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 189A, 192G, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

97Y

multimer interface
16S, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64E, 91I, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 189A, 192G, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

116W

multimer interface
16S, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64E, 91I, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 189A, 192G, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

117M

multimer interface
16S, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64E, 91I, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 189A, 192G, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

118A

multimer interface
16S, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64E, 91I, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 189A, 192G, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

120D

multimer interface
16S, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64E, 91I, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 189A, 192G, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

121G

multimer interface
16S, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64E, 91I, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 189A, 192G, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

122N

multimer interface
16S, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64E, 91I, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 189A, 192G, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

124R

multimer interface
16S, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64E, 91I, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 189A, 192G, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

126L

multimer interface
16S, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64E, 91I, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 189A, 192G, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

127R

multimer interface
16S, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64E, 91I, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 189A, 192G, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

130T

multimer interface
16S, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64E, 91I, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 189A, 192G, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

131P

multimer interface
16S, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64E, 91I, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 189A, 192G, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

133R

multimer interface
16S, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64E, 91I, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 189A, 192G, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

176E

multimer interface
16S, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64E, 91I, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 189A, 192G, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

178L

multimer interface
16S, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64E, 91I, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 189A, 192G, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

179F

multimer interface
16S, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64E, 91I, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 189A, 192G, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

180T

multimer interface
16S, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64E, 91I, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 189A, 192G, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

181P

multimer interface
16S, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64E, 91I, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 189A, 192G, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

182D

multimer interface
16S, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64E, 91I, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 189A, 192G, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

186I

multimer interface
16S, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64E, 91I, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 189A, 192G, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

187K

multimer interface
16S, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64E, 91I, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 189A, 192G, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

189A

multimer interface
16S, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64E, 91I, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 189A, 192G, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

192G

multimer interface
16S, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64E, 91I, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 189A, 192G, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

204H

multimer interface
16S, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64E, 91I, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 189A, 192G, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

205Q

multimer interface
16S, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64E, 91I, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 189A, 192G, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

206L

multimer interface
16S, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64E, 91I, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 189A, 192G, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

207R

multimer interface
16S, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64E, 91I, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 189A, 192G, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

210N

multimer interface
16S, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64E, 91I, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 189A, 192G, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

214D

multimer interface
16S, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64E, 91I, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 189A, 192G, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

217T

multimer interface
16S, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64E, 91I, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 189A, 192G, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

218E

multimer interface
16S, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64E, 91I, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 189A, 192G, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

221K

multimer interface
16S, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64E, 91I, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 189A, 192G, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

222K

multimer interface
16S, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64E, 91I, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 189A, 192G, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

235C

multimer interface
16S, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64E, 91I, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 189A, 192G, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

236D

multimer interface
16S, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64E, 91I, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 189A, 192G, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

237G

multimer interface
16S, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64E, 91I, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 189A, 192G, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

238D

multimer interface
16S, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64E, 91I, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 189A, 192G, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

239R

multimer interface
16S, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64E, 91I, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 189A, 192G, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

241Y

multimer interface
16S, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64E, 91I, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 189A, 192G, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

260Q

multimer interface
16S, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64E, 91I, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 189A, 192G, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

279R

multimer interface
16S, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64E, 91I, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 189A, 192G, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

281H

multimer interface
16S, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64E, 91I, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 189A, 192G, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

282R

multimer interface
16S, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60P, 61D, 64E, 91I, 96R, 97Y, 116W, 117M, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130T, 131P, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 189A, 192G, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)
catalytic triad cd...

45E

catalytic triad
45E, 114K, 175C
CDD
cd07570 (GAT_Gln-NAD-synth)

114K

catalytic triad
45E, 114K, 175C
CDD
cd07570 (GAT_Gln-NAD-synth)

175C

catalytic triad
45E, 114K, 175C
CDD
cd07570 (GAT_Gln-NAD-synth)
active site cd07570

45E

active site
45E, 114K, 118A, 120D, 123Y, 125E, 175C, 176E, 179F, 208K
CDD
cd07570 (GAT_Gln-NAD-synth)

114K

active site
45E, 114K, 118A, 120D, 123Y, 125E, 175C, 176E, 179F, 208K
CDD
cd07570 (GAT_Gln-NAD-synth)

118A

active site
45E, 114K, 118A, 120D, 123Y, 125E, 175C, 176E, 179F, 208K
CDD
cd07570 (GAT_Gln-NAD-synth)

120D

active site
45E, 114K, 118A, 120D, 123Y, 125E, 175C, 176E, 179F, 208K
CDD
cd07570 (GAT_Gln-NAD-synth)

123Y

active site
45E, 114K, 118A, 120D, 123Y, 125E, 175C, 176E, 179F, 208K
CDD
cd07570 (GAT_Gln-NAD-synth)

125E

active site
45E, 114K, 118A, 120D, 123Y, 125E, 175C, 176E, 179F, 208K
CDD
cd07570 (GAT_Gln-NAD-synth)

175C

active site
45E, 114K, 118A, 120D, 123Y, 125E, 175C, 176E, 179F, 208K
CDD
cd07570 (GAT_Gln-NAD-synth)

176E

active site
45E, 114K, 118A, 120D, 123Y, 125E, 175C, 176E, 179F, 208K
CDD
cd07570 (GAT_Gln-NAD-synth)

179F

active site
45E, 114K, 118A, 120D, 123Y, 125E, 175C, 176E, 179F, 208K
CDD
cd07570 (GAT_Gln-NAD-synth)

208K

active site
45E, 114K, 118A, 120D, 123Y, 125E, 175C, 176E, 179F, 208K
CDD
cd07570 (GAT_Gln-NAD-synth)
protein interface ...

116W

protein interface 1
116W, 117M, 118A, 120D, 121G, 122N, 124R, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

117M

protein interface 1
116W, 117M, 118A, 120D, 121G, 122N, 124R, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

118A

protein interface 1
116W, 117M, 118A, 120D, 121G, 122N, 124R, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

120D

protein interface 1
116W, 117M, 118A, 120D, 121G, 122N, 124R, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

121G

protein interface 1
116W, 117M, 118A, 120D, 121G, 122N, 124R, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

122N

protein interface 1
116W, 117M, 118A, 120D, 121G, 122N, 124R, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

124R

protein interface 1
116W, 117M, 118A, 120D, 121G, 122N, 124R, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

133R

protein interface 1
116W, 117M, 118A, 120D, 121G, 122N, 124R, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

176E

protein interface 1
116W, 117M, 118A, 120D, 121G, 122N, 124R, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

178L

protein interface 1
116W, 117M, 118A, 120D, 121G, 122N, 124R, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

179F

protein interface 1
116W, 117M, 118A, 120D, 121G, 122N, 124R, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

180T

protein interface 1
116W, 117M, 118A, 120D, 121G, 122N, 124R, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

181P

protein interface 1
116W, 117M, 118A, 120D, 121G, 122N, 124R, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

182D

protein interface 1
116W, 117M, 118A, 120D, 121G, 122N, 124R, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

186I

protein interface 1
116W, 117M, 118A, 120D, 121G, 122N, 124R, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

187K

protein interface 1
116W, 117M, 118A, 120D, 121G, 122N, 124R, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

204H

protein interface 1
116W, 117M, 118A, 120D, 121G, 122N, 124R, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

205Q

protein interface 1
116W, 117M, 118A, 120D, 121G, 122N, 124R, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

206L

protein interface 1
116W, 117M, 118A, 120D, 121G, 122N, 124R, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

207R

protein interface 1
116W, 117M, 118A, 120D, 121G, 122N, 124R, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

210N

protein interface 1
116W, 117M, 118A, 120D, 121G, 122N, 124R, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

214D

protein interface 1
116W, 117M, 118A, 120D, 121G, 122N, 124R, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

217T

protein interface 1
116W, 117M, 118A, 120D, 121G, 122N, 124R, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

218E

protein interface 1
116W, 117M, 118A, 120D, 121G, 122N, 124R, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

221K

protein interface 1
116W, 117M, 118A, 120D, 121G, 122N, 124R, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

222K

protein interface 1
116W, 117M, 118A, 120D, 121G, 122N, 124R, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

235C

protein interface 1
116W, 117M, 118A, 120D, 121G, 122N, 124R, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

237G

protein interface 1
116W, 117M, 118A, 120D, 121G, 122N, 124R, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

238D

protein interface 1
116W, 117M, 118A, 120D, 121G, 122N, 124R, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

239R

protein interface 1
116W, 117M, 118A, 120D, 121G, 122N, 124R, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

241Y

protein interface 1
116W, 117M, 118A, 120D, 121G, 122N, 124R, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

260Q

protein interface 1
116W, 117M, 118A, 120D, 121G, 122N, 124R, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

281H

protein interface 1
116W, 117M, 118A, 120D, 121G, 122N, 124R, 133R, 176E, 178L, 179F, 180T, 181P, 182D, 186I, 187K, 204H, 205Q, 206L, 207R, 210N, 214D, 217T, 218E, 221K, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)
homodimer interfac...

338G

homodimer interface
338G, 339P, 342W, 345D, 346Y, 447Y, 448H, 449V, 450D, 453I, 454D, 457T, 458K, 486A, 490I, 493R, 494I, 496M, 497V, 498L, 500Y, 501L, 502F, 504Q, 505L, 535K, 536Y, 539S, 540S, 541A, 542D, 543I, 544N, 547G, 548G, 655H, 657M
CDD
cd00553 (NAD_synthase)

339P

homodimer interface
338G, 339P, 342W, 345D, 346Y, 447Y, 448H, 449V, 450D, 453I, 454D, 457T, 458K, 486A, 490I, 493R, 494I, 496M, 497V, 498L, 500Y, 501L, 502F, 504Q, 505L, 535K, 536Y, 539S, 540S, 541A, 542D, 543I, 544N, 547G, 548G, 655H, 657M
CDD
cd00553 (NAD_synthase)

342W

homodimer interface
338G, 339P, 342W, 345D, 346Y, 447Y, 448H, 449V, 450D, 453I, 454D, 457T, 458K, 486A, 490I, 493R, 494I, 496M, 497V, 498L, 500Y, 501L, 502F, 504Q, 505L, 535K, 536Y, 539S, 540S, 541A, 542D, 543I, 544N, 547G, 548G, 655H, 657M
CDD
cd00553 (NAD_synthase)

345D

homodimer interface
338G, 339P, 342W, 345D, 346Y, 447Y, 448H, 449V, 450D, 453I, 454D, 457T, 458K, 486A, 490I, 493R, 494I, 496M, 497V, 498L, 500Y, 501L, 502F, 504Q, 505L, 535K, 536Y, 539S, 540S, 541A, 542D, 543I, 544N, 547G, 548G, 655H, 657M
CDD
cd00553 (NAD_synthase)

346Y

homodimer interface
338G, 339P, 342W, 345D, 346Y, 447Y, 448H, 449V, 450D, 453I, 454D, 457T, 458K, 486A, 490I, 493R, 494I, 496M, 497V, 498L, 500Y, 501L, 502F, 504Q, 505L, 535K, 536Y, 539S, 540S, 541A, 542D, 543I, 544N, 547G, 548G, 655H, 657M
CDD
cd00553 (NAD_synthase)

447Y

homodimer interface
338G, 339P, 342W, 345D, 346Y, 447Y, 448H, 449V, 450D, 453I, 454D, 457T, 458K, 486A, 490I, 493R, 494I, 496M, 497V, 498L, 500Y, 501L, 502F, 504Q, 505L, 535K, 536Y, 539S, 540S, 541A, 542D, 543I, 544N, 547G, 548G, 655H, 657M
CDD
cd00553 (NAD_synthase)

448H

homodimer interface
338G, 339P, 342W, 345D, 346Y, 447Y, 448H, 449V, 450D, 453I, 454D, 457T, 458K, 486A, 490I, 493R, 494I, 496M, 497V, 498L, 500Y, 501L, 502F, 504Q, 505L, 535K, 536Y, 539S, 540S, 541A, 542D, 543I, 544N, 547G, 548G, 655H, 657M
CDD
cd00553 (NAD_synthase)

449V

homodimer interface
338G, 339P, 342W, 345D, 346Y, 447Y, 448H, 449V, 450D, 453I, 454D, 457T, 458K, 486A, 490I, 493R, 494I, 496M, 497V, 498L, 500Y, 501L, 502F, 504Q, 505L, 535K, 536Y, 539S, 540S, 541A, 542D, 543I, 544N, 547G, 548G, 655H, 657M
CDD
cd00553 (NAD_synthase)

450D

homodimer interface
338G, 339P, 342W, 345D, 346Y, 447Y, 448H, 449V, 450D, 453I, 454D, 457T, 458K, 486A, 490I, 493R, 494I, 496M, 497V, 498L, 500Y, 501L, 502F, 504Q, 505L, 535K, 536Y, 539S, 540S, 541A, 542D, 543I, 544N, 547G, 548G, 655H, 657M
CDD
cd00553 (NAD_synthase)

453I

homodimer interface
338G, 339P, 342W, 345D, 346Y, 447Y, 448H, 449V, 450D, 453I, 454D, 457T, 458K, 486A, 490I, 493R, 494I, 496M, 497V, 498L, 500Y, 501L, 502F, 504Q, 505L, 535K, 536Y, 539S, 540S, 541A, 542D, 543I, 544N, 547G, 548G, 655H, 657M
CDD
cd00553 (NAD_synthase)

454D

homodimer interface
338G, 339P, 342W, 345D, 346Y, 447Y, 448H, 449V, 450D, 453I, 454D, 457T, 458K, 486A, 490I, 493R, 494I, 496M, 497V, 498L, 500Y, 501L, 502F, 504Q, 505L, 535K, 536Y, 539S, 540S, 541A, 542D, 543I, 544N, 547G, 548G, 655H, 657M
CDD
cd00553 (NAD_synthase)

457T

homodimer interface
338G, 339P, 342W, 345D, 346Y, 447Y, 448H, 449V, 450D, 453I, 454D, 457T, 458K, 486A, 490I, 493R, 494I, 496M, 497V, 498L, 500Y, 501L, 502F, 504Q, 505L, 535K, 536Y, 539S, 540S, 541A, 542D, 543I, 544N, 547G, 548G, 655H, 657M
CDD
cd00553 (NAD_synthase)

458K

homodimer interface
338G, 339P, 342W, 345D, 346Y, 447Y, 448H, 449V, 450D, 453I, 454D, 457T, 458K, 486A, 490I, 493R, 494I, 496M, 497V, 498L, 500Y, 501L, 502F, 504Q, 505L, 535K, 536Y, 539S, 540S, 541A, 542D, 543I, 544N, 547G, 548G, 655H, 657M
CDD
cd00553 (NAD_synthase)

486A

homodimer interface
338G, 339P, 342W, 345D, 346Y, 447Y, 448H, 449V, 450D, 453I, 454D, 457T, 458K, 486A, 490I, 493R, 494I, 496M, 497V, 498L, 500Y, 501L, 502F, 504Q, 505L, 535K, 536Y, 539S, 540S, 541A, 542D, 543I, 544N, 547G, 548G, 655H, 657M
CDD
cd00553 (NAD_synthase)

490I

homodimer interface
338G, 339P, 342W, 345D, 346Y, 447Y, 448H, 449V, 450D, 453I, 454D, 457T, 458K, 486A, 490I, 493R, 494I, 496M, 497V, 498L, 500Y, 501L, 502F, 504Q, 505L, 535K, 536Y, 539S, 540S, 541A, 542D, 543I, 544N, 547G, 548G, 655H, 657M
CDD
cd00553 (NAD_synthase)

493R

homodimer interface
338G, 339P, 342W, 345D, 346Y, 447Y, 448H, 449V, 450D, 453I, 454D, 457T, 458K, 486A, 490I, 493R, 494I, 496M, 497V, 498L, 500Y, 501L, 502F, 504Q, 505L, 535K, 536Y, 539S, 540S, 541A, 542D, 543I, 544N, 547G, 548G, 655H, 657M
CDD
cd00553 (NAD_synthase)

494I

homodimer interface
338G, 339P, 342W, 345D, 346Y, 447Y, 448H, 449V, 450D, 453I, 454D, 457T, 458K, 486A, 490I, 493R, 494I, 496M, 497V, 498L, 500Y, 501L, 502F, 504Q, 505L, 535K, 536Y, 539S, 540S, 541A, 542D, 543I, 544N, 547G, 548G, 655H, 657M
CDD
cd00553 (NAD_synthase)

496M

homodimer interface
338G, 339P, 342W, 345D, 346Y, 447Y, 448H, 449V, 450D, 453I, 454D, 457T, 458K, 486A, 490I, 493R, 494I, 496M, 497V, 498L, 500Y, 501L, 502F, 504Q, 505L, 535K, 536Y, 539S, 540S, 541A, 542D, 543I, 544N, 547G, 548G, 655H, 657M
CDD
cd00553 (NAD_synthase)

497V

homodimer interface
338G, 339P, 342W, 345D, 346Y, 447Y, 448H, 449V, 450D, 453I, 454D, 457T, 458K, 486A, 490I, 493R, 494I, 496M, 497V, 498L, 500Y, 501L, 502F, 504Q, 505L, 535K, 536Y, 539S, 540S, 541A, 542D, 543I, 544N, 547G, 548G, 655H, 657M
CDD
cd00553 (NAD_synthase)

498L

homodimer interface
338G, 339P, 342W, 345D, 346Y, 447Y, 448H, 449V, 450D, 453I, 454D, 457T, 458K, 486A, 490I, 493R, 494I, 496M, 497V, 498L, 500Y, 501L, 502F, 504Q, 505L, 535K, 536Y, 539S, 540S, 541A, 542D, 543I, 544N, 547G, 548G, 655H, 657M
CDD
cd00553 (NAD_synthase)

500Y

homodimer interface
338G, 339P, 342W, 345D, 346Y, 447Y, 448H, 449V, 450D, 453I, 454D, 457T, 458K, 486A, 490I, 493R, 494I, 496M, 497V, 498L, 500Y, 501L, 502F, 504Q, 505L, 535K, 536Y, 539S, 540S, 541A, 542D, 543I, 544N, 547G, 548G, 655H, 657M
CDD
cd00553 (NAD_synthase)

501L

homodimer interface
338G, 339P, 342W, 345D, 346Y, 447Y, 448H, 449V, 450D, 453I, 454D, 457T, 458K, 486A, 490I, 493R, 494I, 496M, 497V, 498L, 500Y, 501L, 502F, 504Q, 505L, 535K, 536Y, 539S, 540S, 541A, 542D, 543I, 544N, 547G, 548G, 655H, 657M
CDD
cd00553 (NAD_synthase)

502F

homodimer interface
338G, 339P, 342W, 345D, 346Y, 447Y, 448H, 449V, 450D, 453I, 454D, 457T, 458K, 486A, 490I, 493R, 494I, 496M, 497V, 498L, 500Y, 501L, 502F, 504Q, 505L, 535K, 536Y, 539S, 540S, 541A, 542D, 543I, 544N, 547G, 548G, 655H, 657M
CDD
cd00553 (NAD_synthase)

504Q

homodimer interface
338G, 339P, 342W, 345D, 346Y, 447Y, 448H, 449V, 450D, 453I, 454D, 457T, 458K, 486A, 490I, 493R, 494I, 496M, 497V, 498L, 500Y, 501L, 502F, 504Q, 505L, 535K, 536Y, 539S, 540S, 541A, 542D, 543I, 544N, 547G, 548G, 655H, 657M
CDD
cd00553 (NAD_synthase)

505L

homodimer interface
338G, 339P, 342W, 345D, 346Y, 447Y, 448H, 449V, 450D, 453I, 454D, 457T, 458K, 486A, 490I, 493R, 494I, 496M, 497V, 498L, 500Y, 501L, 502F, 504Q, 505L, 535K, 536Y, 539S, 540S, 541A, 542D, 543I, 544N, 547G, 548G, 655H, 657M
CDD
cd00553 (NAD_synthase)

535K

homodimer interface
338G, 339P, 342W, 345D, 346Y, 447Y, 448H, 449V, 450D, 453I, 454D, 457T, 458K, 486A, 490I, 493R, 494I, 496M, 497V, 498L, 500Y, 501L, 502F, 504Q, 505L, 535K, 536Y, 539S, 540S, 541A, 542D, 543I, 544N, 547G, 548G, 655H, 657M
CDD
cd00553 (NAD_synthase)

536Y

homodimer interface
338G, 339P, 342W, 345D, 346Y, 447Y, 448H, 449V, 450D, 453I, 454D, 457T, 458K, 486A, 490I, 493R, 494I, 496M, 497V, 498L, 500Y, 501L, 502F, 504Q, 505L, 535K, 536Y, 539S, 540S, 541A, 542D, 543I, 544N, 547G, 548G, 655H, 657M
CDD
cd00553 (NAD_synthase)

539S

homodimer interface
338G, 339P, 342W, 345D, 346Y, 447Y, 448H, 449V, 450D, 453I, 454D, 457T, 458K, 486A, 490I, 493R, 494I, 496M, 497V, 498L, 500Y, 501L, 502F, 504Q, 505L, 535K, 536Y, 539S, 540S, 541A, 542D, 543I, 544N, 547G, 548G, 655H, 657M
CDD
cd00553 (NAD_synthase)

540S

homodimer interface
338G, 339P, 342W, 345D, 346Y, 447Y, 448H, 449V, 450D, 453I, 454D, 457T, 458K, 486A, 490I, 493R, 494I, 496M, 497V, 498L, 500Y, 501L, 502F, 504Q, 505L, 535K, 536Y, 539S, 540S, 541A, 542D, 543I, 544N, 547G, 548G, 655H, 657M
CDD
cd00553 (NAD_synthase)

541A

homodimer interface
338G, 339P, 342W, 345D, 346Y, 447Y, 448H, 449V, 450D, 453I, 454D, 457T, 458K, 486A, 490I, 493R, 494I, 496M, 497V, 498L, 500Y, 501L, 502F, 504Q, 505L, 535K, 536Y, 539S, 540S, 541A, 542D, 543I, 544N, 547G, 548G, 655H, 657M
CDD
cd00553 (NAD_synthase)

542D

homodimer interface
338G, 339P, 342W, 345D, 346Y, 447Y, 448H, 449V, 450D, 453I, 454D, 457T, 458K, 486A, 490I, 493R, 494I, 496M, 497V, 498L, 500Y, 501L, 502F, 504Q, 505L, 535K, 536Y, 539S, 540S, 541A, 542D, 543I, 544N, 547G, 548G, 655H, 657M
CDD
cd00553 (NAD_synthase)

543I

homodimer interface
338G, 339P, 342W, 345D, 346Y, 447Y, 448H, 449V, 450D, 453I, 454D, 457T, 458K, 486A, 490I, 493R, 494I, 496M, 497V, 498L, 500Y, 501L, 502F, 504Q, 505L, 535K, 536Y, 539S, 540S, 541A, 542D, 543I, 544N, 547G, 548G, 655H, 657M
CDD
cd00553 (NAD_synthase)

544N

homodimer interface
338G, 339P, 342W, 345D, 346Y, 447Y, 448H, 449V, 450D, 453I, 454D, 457T, 458K, 486A, 490I, 493R, 494I, 496M, 497V, 498L, 500Y, 501L, 502F, 504Q, 505L, 535K, 536Y, 539S, 540S, 541A, 542D, 543I, 544N, 547G, 548G, 655H, 657M
CDD
cd00553 (NAD_synthase)

547G

homodimer interface
338G, 339P, 342W, 345D, 346Y, 447Y, 448H, 449V, 450D, 453I, 454D, 457T, 458K, 486A, 490I, 493R, 494I, 496M, 497V, 498L, 500Y, 501L, 502F, 504Q, 505L, 535K, 536Y, 539S, 540S, 541A, 542D, 543I, 544N, 547G, 548G, 655H, 657M
CDD
cd00553 (NAD_synthase)

548G

homodimer interface
338G, 339P, 342W, 345D, 346Y, 447Y, 448H, 449V, 450D, 453I, 454D, 457T, 458K, 486A, 490I, 493R, 494I, 496M, 497V, 498L, 500Y, 501L, 502F, 504Q, 505L, 535K, 536Y, 539S, 540S, 541A, 542D, 543I, 544N, 547G, 548G, 655H, 657M
CDD
cd00553 (NAD_synthase)

655H

homodimer interface
338G, 339P, 342W, 345D, 346Y, 447Y, 448H, 449V, 450D, 453I, 454D, 457T, 458K, 486A, 490I, 493R, 494I, 496M, 497V, 498L, 500Y, 501L, 502F, 504Q, 505L, 535K, 536Y, 539S, 540S, 541A, 542D, 543I, 544N, 547G, 548G, 655H, 657M
CDD
cd00553 (NAD_synthase)

657M

homodimer interface
338G, 339P, 342W, 345D, 346Y, 447Y, 448H, 449V, 450D, 453I, 454D, 457T, 458K, 486A, 490I, 493R, 494I, 496M, 497V, 498L, 500Y, 501L, 502F, 504Q, 505L, 535K, 536Y, 539S, 540S, 541A, 542D, 543I, 544N, 547G, 548G, 655H, 657M
CDD
cd00553 (NAD_synthase)
NAD binding pocket...

357I

NAD binding pocket
357I, 358P, 359L, 360S, 365S, 422C, 423Y, 424M, 485L, 489N, 492A, 493R, 495R, 522S, 527E, 532Y, 533L, 534T, 535K, 538A, 579T, 580A, 582L, 596D, 655H, 656K
CDD
cd00553 (NAD_synthase)

358P

NAD binding pocket
357I, 358P, 359L, 360S, 365S, 422C, 423Y, 424M, 485L, 489N, 492A, 493R, 495R, 522S, 527E, 532Y, 533L, 534T, 535K, 538A, 579T, 580A, 582L, 596D, 655H, 656K
CDD
cd00553 (NAD_synthase)

359L

NAD binding pocket
357I, 358P, 359L, 360S, 365S, 422C, 423Y, 424M, 485L, 489N, 492A, 493R, 495R, 522S, 527E, 532Y, 533L, 534T, 535K, 538A, 579T, 580A, 582L, 596D, 655H, 656K
CDD
cd00553 (NAD_synthase)

360S

NAD binding pocket
357I, 358P, 359L, 360S, 365S, 422C, 423Y, 424M, 485L, 489N, 492A, 493R, 495R, 522S, 527E, 532Y, 533L, 534T, 535K, 538A, 579T, 580A, 582L, 596D, 655H, 656K
CDD
cd00553 (NAD_synthase)

365S

NAD binding pocket
357I, 358P, 359L, 360S, 365S, 422C, 423Y, 424M, 485L, 489N, 492A, 493R, 495R, 522S, 527E, 532Y, 533L, 534T, 535K, 538A, 579T, 580A, 582L, 596D, 655H, 656K
CDD
cd00553 (NAD_synthase)

422C

NAD binding pocket
357I, 358P, 359L, 360S, 365S, 422C, 423Y, 424M, 485L, 489N, 492A, 493R, 495R, 522S, 527E, 532Y, 533L, 534T, 535K, 538A, 579T, 580A, 582L, 596D, 655H, 656K
CDD
cd00553 (NAD_synthase)

423Y

NAD binding pocket
357I, 358P, 359L, 360S, 365S, 422C, 423Y, 424M, 485L, 489N, 492A, 493R, 495R, 522S, 527E, 532Y, 533L, 534T, 535K, 538A, 579T, 580A, 582L, 596D, 655H, 656K
CDD
cd00553 (NAD_synthase)

424M

NAD binding pocket
357I, 358P, 359L, 360S, 365S, 422C, 423Y, 424M, 485L, 489N, 492A, 493R, 495R, 522S, 527E, 532Y, 533L, 534T, 535K, 538A, 579T, 580A, 582L, 596D, 655H, 656K
CDD
cd00553 (NAD_synthase)

485L

NAD binding pocket
357I, 358P, 359L, 360S, 365S, 422C, 423Y, 424M, 485L, 489N, 492A, 493R, 495R, 522S, 527E, 532Y, 533L, 534T, 535K, 538A, 579T, 580A, 582L, 596D, 655H, 656K
CDD
cd00553 (NAD_synthase)

489N

NAD binding pocket
357I, 358P, 359L, 360S, 365S, 422C, 423Y, 424M, 485L, 489N, 492A, 493R, 495R, 522S, 527E, 532Y, 533L, 534T, 535K, 538A, 579T, 580A, 582L, 596D, 655H, 656K
CDD
cd00553 (NAD_synthase)

492A

NAD binding pocket
357I, 358P, 359L, 360S, 365S, 422C, 423Y, 424M, 485L, 489N, 492A, 493R, 495R, 522S, 527E, 532Y, 533L, 534T, 535K, 538A, 579T, 580A, 582L, 596D, 655H, 656K
CDD
cd00553 (NAD_synthase)

493R

NAD binding pocket
357I, 358P, 359L, 360S, 365S, 422C, 423Y, 424M, 485L, 489N, 492A, 493R, 495R, 522S, 527E, 532Y, 533L, 534T, 535K, 538A, 579T, 580A, 582L, 596D, 655H, 656K
CDD
cd00553 (NAD_synthase)

495R

NAD binding pocket
357I, 358P, 359L, 360S, 365S, 422C, 423Y, 424M, 485L, 489N, 492A, 493R, 495R, 522S, 527E, 532Y, 533L, 534T, 535K, 538A, 579T, 580A, 582L, 596D, 655H, 656K
CDD
cd00553 (NAD_synthase)

522S

NAD binding pocket
357I, 358P, 359L, 360S, 365S, 422C, 423Y, 424M, 485L, 489N, 492A, 493R, 495R, 522S, 527E, 532Y, 533L, 534T, 535K, 538A, 579T, 580A, 582L, 596D, 655H, 656K
CDD
cd00553 (NAD_synthase)

527E

NAD binding pocket
357I, 358P, 359L, 360S, 365S, 422C, 423Y, 424M, 485L, 489N, 492A, 493R, 495R, 522S, 527E, 532Y, 533L, 534T, 535K, 538A, 579T, 580A, 582L, 596D, 655H, 656K
CDD
cd00553 (NAD_synthase)

532Y

NAD binding pocket
357I, 358P, 359L, 360S, 365S, 422C, 423Y, 424M, 485L, 489N, 492A, 493R, 495R, 522S, 527E, 532Y, 533L, 534T, 535K, 538A, 579T, 580A, 582L, 596D, 655H, 656K
CDD
cd00553 (NAD_synthase)

533L

NAD binding pocket
357I, 358P, 359L, 360S, 365S, 422C, 423Y, 424M, 485L, 489N, 492A, 493R, 495R, 522S, 527E, 532Y, 533L, 534T, 535K, 538A, 579T, 580A, 582L, 596D, 655H, 656K
CDD
cd00553 (NAD_synthase)

534T

NAD binding pocket
357I, 358P, 359L, 360S, 365S, 422C, 423Y, 424M, 485L, 489N, 492A, 493R, 495R, 522S, 527E, 532Y, 533L, 534T, 535K, 538A, 579T, 580A, 582L, 596D, 655H, 656K
CDD
cd00553 (NAD_synthase)

535K

NAD binding pocket
357I, 358P, 359L, 360S, 365S, 422C, 423Y, 424M, 485L, 489N, 492A, 493R, 495R, 522S, 527E, 532Y, 533L, 534T, 535K, 538A, 579T, 580A, 582L, 596D, 655H, 656K
CDD
cd00553 (NAD_synthase)

538A

NAD binding pocket
357I, 358P, 359L, 360S, 365S, 422C, 423Y, 424M, 485L, 489N, 492A, 493R, 495R, 522S, 527E, 532Y, 533L, 534T, 535K, 538A, 579T, 580A, 582L, 596D, 655H, 656K
CDD
cd00553 (NAD_synthase)

579T

NAD binding pocket
357I, 358P, 359L, 360S, 365S, 422C, 423Y, 424M, 485L, 489N, 492A, 493R, 495R, 522S, 527E, 532Y, 533L, 534T, 535K, 538A, 579T, 580A, 582L, 596D, 655H, 656K
CDD
cd00553 (NAD_synthase)

580A

NAD binding pocket
357I, 358P, 359L, 360S, 365S, 422C, 423Y, 424M, 485L, 489N, 492A, 493R, 495R, 522S, 527E, 532Y, 533L, 534T, 535K, 538A, 579T, 580A, 582L, 596D, 655H, 656K
CDD
cd00553 (NAD_synthase)

582L

NAD binding pocket
357I, 358P, 359L, 360S, 365S, 422C, 423Y, 424M, 485L, 489N, 492A, 493R, 495R, 522S, 527E, 532Y, 533L, 534T, 535K, 538A, 579T, 580A, 582L, 596D, 655H, 656K
CDD
cd00553 (NAD_synthase)

596D

NAD binding pocket
357I, 358P, 359L, 360S, 365S, 422C, 423Y, 424M, 485L, 489N, 492A, 493R, 495R, 522S, 527E, 532Y, 533L, 534T, 535K, 538A, 579T, 580A, 582L, 596D, 655H, 656K
CDD
cd00553 (NAD_synthase)

655H

NAD binding pocket
357I, 358P, 359L, 360S, 365S, 422C, 423Y, 424M, 485L, 489N, 492A, 493R, 495R, 522S, 527E, 532Y, 533L, 534T, 535K, 538A, 579T, 580A, 582L, 596D, 655H, 656K
CDD
cd00553 (NAD_synthase)

656K

NAD binding pocket
357I, 358P, 359L, 360S, 365S, 422C, 423Y, 424M, 485L, 489N, 492A, 493R, 495R, 522S, 527E, 532Y, 533L, 534T, 535K, 538A, 579T, 580A, 582L, 596D, 655H, 656K
CDD
cd00553 (NAD_synthase)
ATP binding pocket...

358P

ATP binding pocket
358P, 359L, 360S, 364D, 365S, 423Y, 424M, 495R, 522S, 551K, 578P, 579T
CDD
cd00553 (NAD_synthase)

359L

ATP binding pocket
358P, 359L, 360S, 364D, 365S, 423Y, 424M, 495R, 522S, 551K, 578P, 579T
CDD
cd00553 (NAD_synthase)

360S

ATP binding pocket
358P, 359L, 360S, 364D, 365S, 423Y, 424M, 495R, 522S, 551K, 578P, 579T
CDD
cd00553 (NAD_synthase)

364D

ATP binding pocket
358P, 359L, 360S, 364D, 365S, 423Y, 424M, 495R, 522S, 551K, 578P, 579T
CDD
cd00553 (NAD_synthase)

365S

ATP binding pocket
358P, 359L, 360S, 364D, 365S, 423Y, 424M, 495R, 522S, 551K, 578P, 579T
CDD
cd00553 (NAD_synthase)

423Y

ATP binding pocket
358P, 359L, 360S, 364D, 365S, 423Y, 424M, 495R, 522S, 551K, 578P, 579T
CDD
cd00553 (NAD_synthase)

424M

ATP binding pocket
358P, 359L, 360S, 364D, 365S, 423Y, 424M, 495R, 522S, 551K, 578P, 579T
CDD
cd00553 (NAD_synthase)

495R

ATP binding pocket
358P, 359L, 360S, 364D, 365S, 423Y, 424M, 495R, 522S, 551K, 578P, 579T
CDD
cd00553 (NAD_synthase)

522S

ATP binding pocket
358P, 359L, 360S, 364D, 365S, 423Y, 424M, 495R, 522S, 551K, 578P, 579T
CDD
cd00553 (NAD_synthase)

551K

ATP binding pocket
358P, 359L, 360S, 364D, 365S, 423Y, 424M, 495R, 522S, 551K, 578P, 579T
CDD
cd00553 (NAD_synthase)

578P

ATP binding pocket
358P, 359L, 360S, 364D, 365S, 423Y, 424M, 495R, 522S, 551K, 578P, 579T
CDD
cd00553 (NAD_synthase)

579T

ATP binding pocket
358P, 359L, 360S, 364D, 365S, 423Y, 424M, 495R, 522S, 551K, 578P, 579T
CDD
cd00553 (NAD_synthase)
Mg binding site cd...

360S

Mg binding site
360S, 364D, 527E, 579T
CDD
cd00553 (NAD_synthase)

364D

Mg binding site
360S, 364D, 527E, 579T
CDD
cd00553 (NAD_synthase)

527E

Mg binding site
360S, 364D, 527E, 579T
CDD
cd00553 (NAD_synthase)

579T

Mg binding site
360S, 364D, 527E, 579T
CDD
cd00553 (NAD_synthase)
active-site loop c...

431A

active-site loop
431A, 575N, 576A, 577T, 578P, 579T, 580A, 581E, 582L, 590V, 591Q, 592S, 593D, 594E, 595R, 596D, 597M
CDD
cd00553 (NAD_synthase)

575N

active-site loop
431A, 575N, 576A, 577T, 578P, 579T, 580A, 581E, 582L, 590V, 591Q, 592S, 593D, 594E, 595R, 596D, 597M
CDD
cd00553 (NAD_synthase)

576A

active-site loop
431A, 575N, 576A, 577T, 578P, 579T, 580A, 581E, 582L, 590V, 591Q, 592S, 593D, 594E, 595R, 596D, 597M
CDD
cd00553 (NAD_synthase)

577T

active-site loop
431A, 575N, 576A, 577T, 578P, 579T, 580A, 581E, 582L, 590V, 591Q, 592S, 593D, 594E, 595R, 596D, 597M
CDD
cd00553 (NAD_synthase)

578P

active-site loop
431A, 575N, 576A, 577T, 578P, 579T, 580A, 581E, 582L, 590V, 591Q, 592S, 593D, 594E, 595R, 596D, 597M
CDD
cd00553 (NAD_synthase)

579T

active-site loop
431A, 575N, 576A, 577T, 578P, 579T, 580A, 581E, 582L, 590V, 591Q, 592S, 593D, 594E, 595R, 596D, 597M
CDD
cd00553 (NAD_synthase)

580A

active-site loop
431A, 575N, 576A, 577T, 578P, 579T, 580A, 581E, 582L, 590V, 591Q, 592S, 593D, 594E, 595R, 596D, 597M
CDD
cd00553 (NAD_synthase)

581E

active-site loop
431A, 575N, 576A, 577T, 578P, 579T, 580A, 581E, 582L, 590V, 591Q, 592S, 593D, 594E, 595R, 596D, 597M
CDD
cd00553 (NAD_synthase)

582L

active-site loop
431A, 575N, 576A, 577T, 578P, 579T, 580A, 581E, 582L, 590V, 591Q, 592S, 593D, 594E, 595R, 596D, 597M
CDD
cd00553 (NAD_synthase)

590V

active-site loop
431A, 575N, 576A, 577T, 578P, 579T, 580A, 581E, 582L, 590V, 591Q, 592S, 593D, 594E, 595R, 596D, 597M
CDD
cd00553 (NAD_synthase)

591Q

active-site loop
431A, 575N, 576A, 577T, 578P, 579T, 580A, 581E, 582L, 590V, 591Q, 592S, 593D, 594E, 595R, 596D, 597M
CDD
cd00553 (NAD_synthase)

592S

active-site loop
431A, 575N, 576A, 577T, 578P, 579T, 580A, 581E, 582L, 590V, 591Q, 592S, 593D, 594E, 595R, 596D, 597M
CDD
cd00553 (NAD_synthase)

593D

active-site loop
431A, 575N, 576A, 577T, 578P, 579T, 580A, 581E, 582L, 590V, 591Q, 592S, 593D, 594E, 595R, 596D, 597M
CDD
cd00553 (NAD_synthase)

594E

active-site loop
431A, 575N, 576A, 577T, 578P, 579T, 580A, 581E, 582L, 590V, 591Q, 592S, 593D, 594E, 595R, 596D, 597M
CDD
cd00553 (NAD_synthase)

595R

active-site loop
431A, 575N, 576A, 577T, 578P, 579T, 580A, 581E, 582L, 590V, 591Q, 592S, 593D, 594E, 595R, 596D, 597M
CDD
cd00553 (NAD_synthase)

596D

active-site loop
431A, 575N, 576A, 577T, 578P, 579T, 580A, 581E, 582L, 590V, 591Q, 592S, 593D, 594E, 595R, 596D, 597M
CDD
cd00553 (NAD_synthase)

597M

active-site loop
431A, 575N, 576A, 577T, 578P, 579T, 580A, 581E, 582L, 590V, 591Q, 592S, 593D, 594E, 595R, 596D, 597M
CDD
cd00553 (NAD_synthase)

Protein sequence

>MCA_04885_1
MVHLVTLATCALNQWSLDFEGNRDRIIESIRQAKKQGAIFRTGPELEVTGYGCLDHFLEPDTYEHSWEVYKEIITHEDTR
DIVIDIGMPIIHNNIRYNCRIISFNKEIFLIRPKLWMANDGNYRELRYFTPWRAQNQSVDFFLPRIIREATNQKVVPFGD
VCLRSNFTLFGFETCEELFTPDSPHIKMALGGVEIFTNSSGSHHQLRKLNTRLDLITEATKKCGGVYLYANQRGCDGDRL
YYDGSAMIVLNGEVVAQGAQFGLRDVEVVVATVDLDTIRAHRASPSFGLQSLTKPSLNLVVKYSSLADGLDLDFDPTITP
TPTRKISYHTPQEEIALGPACWLWDYLRRSKTAGYFIPLSGGIDSCATAVIVHSMCRLVVKEAGEGNKEVIADARRLARV
EEDSDYIPTDPQEFANRIFHTCYMGSENSSAETRKRAKGLAKAIGSYHVDLDIDTVTKAIHELFVTVTGKNPRFKVFGGT
PTENLALQNIQARIRMVLGYLFAQLLPWVRYGGSGGLLVLGSSNVDECLRGYLTKYDASSADINPIGGISKTDLKDFIAY
ARDYFNVPLLDEFLNATPTAELEPITKDYVQSDERDMGMTYDELSVFGRLRKINKCGPYSMFLNLLHEWTPKGLTPEEIA
TKVKRFFYYYAINRHKMTTITPAYHAESYSPDDNRFDLRPFLIIPTFPWASKKIDETVKKYSAPFTPKNEKSD

GO term prediction

Biological Process

GO:0006807 nitrogen compound metabolic process
GO:0009435 NAD biosynthetic process

Molecular Function

GO:0003952 NAD+ synthase (glutamine-hydrolyzing) activity
GO:0005524 ATP binding
GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds

Cellular Component

None predicted.

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Entry type

Status

Per-residue features