Protein

MIA_00796_1

Length
438 amino acids

Browser: contig01:2258112-2259429-

Protein function

EGGNOG:0QEEECPA1carbamoylphosphate synthase
SGD closest match:S000005829CPA1Carbamoyl-phosphate synthase arginine-specific small chain
CGD closest match:CAL0000174966CPA1Carbamoyl-phosphate synthase arginine-specific small chain

Protein alignments

%idAln lengthE-value
MCA_04899_186.848%4410.0MCA_04899_1
A0A0J9XKE1_GEOCN87.500%4000.0Similar to Saccharomyces cerevisiae YOR303W CPA1 Small subunit of carbamoyl phosphate synthetase, which catalyzes a step in the synthesis of citrulline, an arginine OS=Geotrichum candidum GN=BN980_GECA22s01583g PE=3 SV=1
A0A167EYQ7_9ASCO83.704%4050.0Carbamoyl-phosphate synthase (Glutamine-hydrolyzing) CPA1 OS=Sugiyamaella lignohabitans GN=CPA1 PE=3 SV=1
A0A060SWG5_BLAAD82.206%3990.0ARAD1A01496p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A01496g PE=3 SV=1
CARA_YARLI77.000%4000.0Carbamoyl-phosphate synthase arginine-specific small chain OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=CPA1 PE=3 SV=1
A0A1E3PDZ7_9ASCO75.248%4040.0Small subunit of carbamoyl phosphate synthase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_84272 PE=3 SV=1
UniRef50_P2257275.888%3940.0Carbamoyl-phosphate synthase arginine-specific small chain, mitochondrial n=48 Tax=Fungi TaxID=4751 RepID=CARA_NEUCR
A0A1E4TM57_9ASCO76.215%3910.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_1426 PE=3 SV=1
CARA_CANAL74.365%3940.0Carbamoyl-phosphate synthase arginine-specific small chain OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CPA1 PE=3 SV=1
CARA_YEAST66.667%4080.0Carbamoyl-phosphate synthase arginine-specific small chain OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CPA1 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9971
Predicted cleavage: 26

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 400 438

Detailed signature matches

  1. Family IPR006274
    Carbamoyl-phosphate synthase, small subunit
    1. MF_01209 (CPSase_S_...)
    2. TIGR01368
  2. Domain IPR002474
    Carbamoyl-phosphate synthase small subunit, N-terminal domain
    1. SSF52021 (Carbamoyl...)
    2. G3DSA:3.50.30.20
    3. SM01097 (CPSase_sm_...)
    4. PF00988 (CPSase_sm_...)
  3. Domain IPR029062
    Class I glutamine amidotransferase-like
    1. G3DSA:3.40.50...
    2. SSF52317 (Class I g...)
  4. Domain IPR017926
    Glutamine amidotransferase
    1. PF00117 (GATase)
    2. PS51273 (GATASE_TYPE_1)
  5. Domain IPR035686
    Carbamoyl-phosphate synthase small subunit, GATase1 domain
    1. cd01744 (GATase1_CP...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. PR00096 (GATASE)
  2. PR00097 (ANTSNTHASEII)
  3. PR00099 (CPSGATASE)

Residue annotation

  1. catalytic site cd0...
  2. subunit interface ...

Protein sequence

>MIA_00796_1
MFRLAKSLGSSIARRNFSAACALRKASPLTSTSSIGSSALDRATLTIRDGPVFHGKSFGADTNVSGEAVFTTSLVGYPES
MTDPSYRGQIIVFTQPLIGNYGVPSSTTRDDFNLLKYFESPHIQCIGIVVADIAMQYSHWTAVESLAEWCQREGVAAITG
VDTRALVTFLRERGSSLARITIGEEYDADEDEAFVDPGAINLVQKVSTKSPFHVSAGADAHAHVAVIDCGVKENILRSLV
SRGADITVFPYDYPIHKIAHHFDGIFISNGPGDPTHCQSTVYNLKKTMESYEGPIFGICLGHQLLALAAGAKTVKLKYGN
RAHNIPALDLQTGRCHITSQNHGYAVDAATLPSDFKPYFINLNDQSNEGMIHTSRPIFSTQFHPEAKGGPLDSAFLFDKY
IEDVKEYKLKQSLNTRPSPLFVDMLAKERVGVEVHPQS

GO term prediction

Biological Process

GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process
GO:0006541 glutamine metabolic process

Molecular Function

GO:0004088 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity

Cellular Component

None predicted.