Protein

MIA_00773_1

Length
521 amino acids

Browser: contig01:2193273-2194839-

Protein function

EGGNOG:0PGKCTHR4threonine synthase
SGD closest match:S000000649THR4Threonine synthase
CGD closest match:CAL0000193606THR4Threonine synthase

Protein alignments

%idAln lengthE-value
MCA_06068_179.452%5110.0MCA_06068_1
A0A0J9XA92_GEOCN76.008%5210.0Similar to Saccharomyces cerevisiae YCR053W THR4 Threonine synthase OS=Geotrichum candidum GN=BN980_GECA07s03706g PE=4 SV=1
A0A167F2J9_9ASCO68.726%5180.0Threonine synthase THR4 OS=Sugiyamaella lignohabitans GN=THR4 PE=4 SV=1
UniRef50_A0A167F2J968.726%5180.0Threonine synthase THR4 n=4 Tax=Dikarya TaxID=451864 RepID=A0A167F2J9_9ASCO
A0A1E3PIJ9_9ASCO66.987%5210.0Tryptophan synthase beta subunit-like PLP-dependent enzyme OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_46959 PE=4 SV=1
A0A060T8E1_BLAAD66.667%5160.0ARAD1C28644p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C28644g PE=4 SV=1
Q6C0N3_YARLI67.315%5140.0YALI0F23221p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F23221g PE=4 SV=1
A0A1E4TIV0_9ASCO61.122%5170.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_74349 PE=4 SV=1
A0A1D8PNG9_CANAL59.309%5210.0Threonine synthase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=THR4 PE=4 SV=1
THRC_YEAST58.555%5260.0Threonine synthase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=THR4 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.6970
Predicted cleavage: 14

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 50 100 150 200 250 300 350 400 450 521

Detailed signature matches

  1. Family IPR004450
    Threonine synthase-like
    1. TIGR00260
  2. Domain IPR029144
    Threonine synthase, N-terminal
    1. PF14821 (Thr_synth_N)
    2. G3DSA:3.90.13...
  3. Domain IPR001926
    Tryptophan synthase beta subunit-like PLP-dependent enzyme
    1. SSF53686 (Tryptopha...)
    2. PF00291 (PALP)
  4. SITE IPR000634
    Serine/threonine dehydratase, pyridoxal-phosphate-binding site
    1. PS00165 (DEHYDRATAS...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.40.50...
  2. cd01560 (Thr-synth_2)

Residue annotation

  1. catalytic residue ...
  2. pyridoxal 5'-phosp...

Protein sequence

>MIA_00773_1
MVVASQQYFSTRSSSNPISFEEAIMTGLAPDGGLYIPTAIPTLPEDFLTKWANLSFQELAFEILSLYISRQEIPAENLKE
IIEKSYSTFRSKDITPTTTLNKDINLHLLELFHGPTYAFKDVALQFVGNLFDFFLTRRNEGKAPNDPTRETVTVVGATSG
DTGSAAIYGLRNKKNVSVFILFPTGRVSPIQEAQMTSVLDPNIHTISVKGTFDDCQDLVKQVFGDKAFNDKYHVGAVNSI
NWARILAQITYYFHSFFTLARQIEGGAQALAEKINYIVPTGNFGDILAGFYAKQMGLPINKLTVATNSNDILHRFLQSGV
YSKSASVEAGPVVHATLSPAMDILVSSNFERYLWYAARTTTDSNEEAGQLVNQWMADLKATGKFSVSDKVLATARLQFSS
ERASDEETTATIKKVYTEISPKYILDPHTSVAVFGALKTIEKSESADHHHVALSTAHPAKFADAVDLALKGQEGYSFEND
VLPQEFKELPGREKKNLFAEKPDLELIKSIIVDELQKENQA

GO term prediction

Biological Process

GO:0006520 cellular amino acid metabolic process

Molecular Function

GO:0030170 pyridoxal phosphate binding

Cellular Component

None predicted.