Protein

MCA_06068_1

Length
512 amino acids

Gene name: THR4

Description: Threonine synthase

Browser: contigD:3156975-3158514-

RNA-seq: read pairs 5772, FPKM 139.0, percentile rank 83.9% (100% = highest expression)

Protein function

Annotation:THR4Threonine synthase
KEGG:K01733thrC threonine synthase [EC:4.2.3.1]
EGGNOG:0PGKCTHR4threonine synthase
SGD closest match:S000000649THR4Threonine synthase
CGD closest match:CAL0000193606THR4Threonine synthase

Protein alignments

%idAln lengthE-value
MIA_00773_179.45%5110.0MIA_00773_1
A0A0J9XA92_GEOCN74.37%5150.0Similar to Saccharomyces cerevisiae YCR053W THR4 Threonine synthase OS=Geotrichum candidum GN=BN980_GECA07s03706g PE=4 SV=1
A0A060T8E1_BLAAD67.51%5110.0ARAD1C28644p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C28644g PE=4 SV=1
A0A1E3PIJ9_9ASCO67.38%5150.0Tryptophan synthase beta subunit-like PLP-dependent enzyme OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_46959 PE=4 SV=1
A0A167F2J9_9ASCO68.88%5110.0Threonine synthase THR4 OS=Sugiyamaella lignohabitans GN=THR4 PE=4 SV=1
UniRef50_A0A167F2J968.88%5110.0Threonine synthase THR4 n=4 Tax=Dikarya TaxID=451864 RepID=A0A167F2J9_9ASCO
Q6C0N3_YARLI66.02%5120.0YALI0F23221p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F23221g PE=4 SV=1
A0A1E4TIV0_9ASCO61.76%5100.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_74349 PE=4 SV=1
A0A1D8PNG9_CANAL60.27%5160.0Threonine synthase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=THR4 PE=4 SV=1
THRC_YEAST59.38%5170.0Threonine synthase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=THR4 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.4722

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 50 100 150 200 250 300 350 400 450 512

Detailed signature matches

  1. Family IPR004450
    Threonine synthase-like
    1. TIGR00260
  2. Domain IPR029144
    Threonine synthase, N-terminal
    1. PF14821 (Thr_synth_N)
    2. G3DSA:3.90.13...
  3. Domain IPR001926
    Tryptophan synthase beta subunit-like PLP-dependent enzyme
    1. SSF53686 (Tryptopha...)
    2. PF00291 (PALP)
  4. SITE IPR000634
    Serine/threonine dehydratase, pyridoxal-phosphate-binding site
    1. PS00165 (DEHYDRATAS...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:3.40.50...
  3. cd01560 (Thr-synth_2)

Residue annotation

  1. catalytic residue ...
  2. pyridoxal 5'-phosp...

Protein sequence

>MCA_06068_1
MPSYFSTRSSDKPVSFEQAVMTGLAPDGGLYIPTEIPTLPADFLEKWKDYSFQQLAYEILSLYISTDDIPSKDLKDIIEA
SYSTFRSSDITPITTLNEDLNLHLLELFHGPTYAFKDVALQFVGNLFNFFLSRRNQGKDPKDPSRESITVVGATSGDTGS
AAIYGLRNKKDVSVFILFPKGRVSPIQEAQMTSVLDPNIHTITVEGTFDDCQDLVKKVFGDKEFNDKYHIGAVNSINWAR
ILAQITYYFHAYFTLVRKQGKDLANKINFVVPTGNFGDILAGFYAKQMGLPIKNLTIATNSNDILHRFFQSGVYSKAAPE
EKEPVVHATLSPAMDILVSSNFERYLWYAARTSTKTDQEAGALVAKWMNDLKTVGKFDVDPAILETAKAQFTSERASDDE
TIETIKKVYTEVSPKYILDPHSAVAVYGALSMIKSSGDKDVYVALSTAHPAKFADAVDLALKGQEGYSFEDDVLPQEFKE
LPGREKKNLYAEKPDLELLKSIIVEELVKEKA

GO term prediction

Biological Process

GO:0006520 cellular amino acid metabolic process

Molecular Function

GO:0030170 pyridoxal phosphate binding

Cellular Component

None predicted.