Protein

MIA_00724_1

Length
403 amino acids

Browser: contig01:2055046-2056372+

Protein function

EGGNOG:0PFB5PEP2Vacuolar protease A
SGD closest match:S000006075PEP4Saccharopepsin
CGD closest match:CAL0000197684APR1Proteinase A

Protein alignments

%idAln lengthE-value
MCA_05364_183.812%3830.0MCA_05364_1
A0A0J9X3D7_GEOCN74.413%3830.0Similar to Saccharomyces cerevisiae YPL154C PEP4 Vacuolar aspartyl protease (Proteinase A) OS=Geotrichum candidum GN=BN980_GECA01s02760g PE=3 SV=1
A0A1E3PFU8_9ASCO68.394%3860.0Aspartyl proteinase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83756 PE=3 SV=1
A0A060T7R0_BLAAD65.535%3830.0ARAD1B21824p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B21824g PE=3 SV=1
CARP_YEAST67.358%3860.0Saccharopepsin OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PEP4 PE=1 SV=1
UniRef50_P0726767.358%3860.0Saccharopepsin n=516 Tax=Eukaryota TaxID=2759 RepID=CARP_YEAST
Q59U59_CANAL61.519%3951.43e-179Proteinase A OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=APR1 PE=3 SV=1
Q6C080_YARLI64.398%3825.98e-176YALI0F27071p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F27071g PE=3 SV=1
A0A1E4TI13_9ASCO58.486%3831.99e-168Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_123212 PE=3 SV=1
A0A167C0Q5_9ASCO65.527%3516.28e-163Proteinase A OS=Sugiyamaella lignohabitans GN=PEP4 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.3682

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 403

Detailed signature matches

  1. Family IPR001461
    Aspartic peptidase A1 family
    1. PR00792 (PEPSIN)
  2. Domain IPR021109
    Aspartic peptidase domain
    1. G3DSA:2.40.70.10
    2. SSF50630 (Acid prot...)
  3. Domain IPR033121
    Peptidase family A1 domain
    1. PS51767 (PEPTIDASE_A1)
    2. PF00026 (Asp)
  4. SITE IPR001969
    Aspartic peptidase, active site
    1. PS00141 (ASP_PROTEASE)
Unintegrated signatures no IPR
Unintegrated signatures
  1. NON_CYTOPLASM... (N...)
  2. SIGNAL_PEPTIDE (Sig...)
  3. SIGNAL_PEPTID... (S...)
  4. SIGNAL_PEPTID... (S...)
  5. SIGNAL_PEPTID... (S...)
  6. SignalP-noTM

Protein sequence

>MIA_00724_1
MKLTAITLASTLAGSALAGVHKVDIKKMDTSARFHGEAFQDHLRSLGQKYMGLAQKYGAKDNRVPFIGNNVNAEGDYSVP
LGNYLNVQYFADITLGTPPQEFKVVLDTGSSNLWVPGADCNSIACFLHSRYDSSESSSYKANGTEFSIQYGSGSVSGFIS
QDTLTLGDLVIPKQDFGEATNEPGLAFAFGKFDGILGLGFDSISVNHVVPPFYNALNQGLLDEPVFSFKLGDADKDASDG
GTFTIGGTDKSLYTGDITWLPLRRKAYWEVKFDAISLGGETAELENTGAVVDTGTSLLTFPSALAEMINSQIGATKGWNG
QYTVDCATRDSLPDLKFTLDGYNFTLTGFEYTLEVSGSCISAITPMDFPEPVGPLSIVGDAFLRKYYSVYDYGNSAVGLA
KAA

GO term prediction

Biological Process

GO:0006508 proteolysis

Molecular Function

GO:0004190 aspartic-type endopeptidase activity

Cellular Component

None predicted.