Protein
MCA_05364_1
Length
401 amino acids
Gene name: PEP4
Description: Vacuolar aspartic protease (proteinase A)
Browser: contigD:1137272-1139258-
RNA-seq: read pairs 41365, FPKM 1271.4, percentile rank 97.0% (100% = highest expression)
Protein function
| Annotation: | PEP4 | Vacuolar aspartic protease (proteinase A) | |
|---|---|---|---|
| KEGG: | K01381 | PEP4 | saccharopepsin [EC:3.4.23.25] |
| EGGNOG: | 0PFB5 | PEP2 | Vacuolar protease A |
| SGD closest match: | S000006075 | PEP4 | Saccharopepsin |
| CGD closest match: | CAL0000197684 | APR1 | Proteinase A |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_00724_1 | 82.84% | 402 | 0.0 | MIA_00724_1 |
| A0A0J9X3D7_GEOCN | 72.61% | 398 | 0.0 | Similar to Saccharomyces cerevisiae YPL154C PEP4 Vacuolar aspartyl protease (Proteinase A) OS=Geotrichum candidum GN=BN980_GECA01s02760g PE=3 SV=1 |
| CARP_YEAST | 67.62% | 386 | 0.0 | Saccharopepsin OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PEP4 PE=1 SV=1 |
| UniRef50_P07267 | 67.62% | 386 | 0.0 | Saccharopepsin n=516 Tax=Eukaryota TaxID=2759 RepID=CARP_YEAST |
| A0A060T7R0_BLAAD | 63.09% | 401 | 0.0 | ARAD1B21824p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B21824g PE=3 SV=1 |
| A0A1E3PFU8_9ASCO | 65.27% | 406 | 0.0 | Aspartyl proteinase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83756 PE=3 SV=1 |
| Q59U59_CANAL | 60.24% | 415 | 0.0 | Proteinase A OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=APR1 PE=3 SV=1 |
| Q6C080_YARLI | 62.84% | 401 | 7e-175 | YALI0F27071p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F27071g PE=3 SV=1 |
| A0A1E4TI13_9ASCO | 56.62% | 385 | 1e-164 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_123212 PE=3 SV=1 |
| A0A167C0Q5_9ASCO | 68.79% | 330 | 2e-163 | Proteinase A OS=Sugiyamaella lignohabitans GN=PEP4 PE=3 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.3574
Protein family membership
- Aspartic peptidase A1 family (IPR001461)
Domains and repeats
-
Domain
1
50
100
150
200
250
300
350
401
Detailed signature matches
no IPR
Unintegrated signatures
-
NON_CYTOPLASM... (N...)
-
SIGNAL_PEPTIDE (Sig...)
-
SIGNAL_PEPTID... (S...)
-
SIGNAL_PEPTID... (S...)
-
SIGNAL_PEPTID... (S...)
-
Protein sequence
>MCA_05364_1 MKFTALTLLSTVTGTAFAGVHKVNLKKINDPHRYEGAAFGDHLKSLGQKYMGLAQKTLGKPVENPFVQLNADGSSSIPLG NYLNVQYFADITLGTPPQAFKVVLDTGSSNLWVPSSECNSIACFLHNRYDASASSSYVENGTEFKIQYGSGSVSGKISQD TLTLGDLVIPKQDFGEATNEPGLAFAFGKFDGILGLGFDSISVNHVVPPFYNAMDKGLIDEPVFSFRLGDADKDAEDGGT FTIGGTDESLYEGKITWLPVRRKAYWEVKFDAIGLGKEFAELENTGAVIDTGTSLLTFPSALAEMINSQIGAKKGWNGQY SVDCATRDSLPDLTFTLDGYNFTLSSYEYTLEVSGSCISAITPMDFPEPVGPLAIVGDAFLRKYYSVYDYGHSAVGLAKS T
GO term prediction
Biological Process
GO:0006508 proteolysis
Molecular Function
GO:0004190 aspartic-type endopeptidase activity
Cellular Component
None predicted.