Protein
MIA_00711_1
Length
216 amino acids
Browser: contig01:2036756-2037467-
Protein function
| EGGNOG: | 0PKGJ | ERD2 | Required for the retention of luminal endoplasmic reticulum proteins. Determines the specificity of the luminal ER protein retention system. Also required for normal vesicular traffic through the Golgi (By similarity) |
|---|---|---|---|
| SGD closest match: | S000000136 | ERD2 | ER lumen protein-retaining receptor |
| CGD closest match: | CAL0000188440 | orf19.2756 | Uncharacterized protein |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MCA_01770_1 | 71.622% | 222 | 1.93e-115 | MCA_01770_1 |
| A0A0J9X5A7_GEOCN | 72.685% | 216 | 5.58e-114 | ER lumen protein-retaining receptor OS=Geotrichum candidum GN=BN980_GECA03s01088g PE=3 SV=1 |
| A0A1E4TJ94_9ASCO | 57.870% | 216 | 2.00e-87 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_76607 PE=4 SV=1 |
| UniRef50_A0A0C7BA72 | 56.944% | 216 | 6.91e-83 | Putative ER lumen protein retaining receptor n=9 Tax=Eukaryota TaxID=2759 RepID=A0A0C7BA72_9FUNG |
| A0A1E3PT81_9ASCO | 55.093% | 216 | 7.78e-86 | ER lumen protein-retaining receptor OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_81519 PE=3 SV=1 |
| A0A060T7C3_BLAAD | 60.000% | 215 | 3.32e-85 | ER lumen protein-retaining receptor OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C20372g PE=3 SV=1 |
| Q6CA22_YARLI | 55.000% | 220 | 1.33e-81 | YALI0D06545p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D06545g PE=4 SV=1 |
| Q5AF52_CANAL | 52.294% | 218 | 1.11e-78 | Uncharacterized protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.2756 PE=4 SV=1 |
| ERD2_YEAST | 49.321% | 221 | 4.76e-71 | ER lumen protein-retaining receptor OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ERD2 PE=3 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.8405
Predicted cleavage: 84
Protein family membership
- ER lumen protein retaining receptor (IPR000133)
Domains and repeats
None predicted.
Detailed signature matches
no IPR
Unintegrated signatures
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CYTOPLASMIC_D... (C...)
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NON_CYTOPLASM... (N...)
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SIGNAL_PEPTIDE (Sig...)
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SIGNAL_PEPTID... (S...)
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SIGNAL_PEPTID... (S...)
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SIGNAL_PEPTID... (S...)
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TRANSMEMBRANE (Tran...)
Protein sequence
>MIA_00711_1 MNIFRFLADMSHVLSILLLLQKIRSSNSVAGISFKTQALYALVFVTRYLDVFLYFVSIYNTLMKILFLGTSFYTLHVMYK KRDSGTIASNTIDTFRVEFLLAGSLALALIFPSERIYSVTNVLWTFSLWLESVAILPQLFMLQRTGQAESLTVHYIFALG LYRGFYVLNWIYRYYFDNWFSLTSFVTGIIQTALYSDFFWVYYQKVLKGKKFELPQ
GO term prediction
Biological Process
GO:0006621 protein retention in ER lumen
Molecular Function
GO:0046923 ER retention sequence binding
Cellular Component
GO:0016021 integral component of membrane