Protein
MIA_00708_1
Length
915 amino acids
Browser: contig01:2030607-2033639-
Protein function
| EGGNOG: | 0PQNH | DEF1 | RNA polymerase II degradation factor recruits the ubiquitination machinery to the RNA polymerase II for polyubiquitination, removal and degradation, when RAD26 fails to efficiently displace stalled RNA polymerase II. Also involved in telomere length regulation (By similarity) |
|---|
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| A0A0J9X5F4_GEOCN | 70.000% | 60 | 1.73e-20 | Similar to Saccharomyces cerevisiae YKL054C DEF1 RNAPII degradation factor OS=Geotrichum candidum GN=BN980_GECA03s01055g PE=4 SV=1 |
| UniRef50_A0A0J9X5F4 | 70.000% | 60 | 3.53e-17 | Similar to Saccharomyces cerevisiae YKL054C DEF1 RNAPII degradation factor n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X5F4_GEOCN |
| A0A1E3PFF5_9ASCO | 63.333% | 60 | 6.47e-19 | Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_43929 PE=4 SV=1 |
| A0A060SX38_BLAAD | 60.000% | 60 | 1.81e-18 | ARAD1A01518p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A01518g PE=4 SV=1 |
| Q6CCF1_YARLI | 60.345% | 58 | 1.48e-17 | YALI0C09933p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C09933g PE=4 SV=1 |
| MCA_01767_1 | 40.066% | 302 | 6.77e-17 | MCA_01767_1 |
| A0A167EYP5_9ASCO | 58.000% | 50 | 6.27e-13 | RNAPII degradation factor (Predicted) OS=Sugiyamaella lignohabitans GN=AWJ20_2220 PE=4 SV=1 |
| A0A1E4TI01_9ASCO | 45.238% | 42 | 7.90e-07 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_57627 PE=4 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0471
Protein family membership
None predicted.
Domains and repeats
-
Domain
1
100
200
300
400
500
600
700
800
915
Detailed signature matches
no IPR
Unintegrated signatures
-
-
-
-
cd14368 (CUE_DEF1_like)
-
mobidb-lite (disord...)
Protein sequence
>MIA_00708_1 MTTSATPQPDSKPPKKTPSGPSSTSTSTSSYSRQRRSQHASSHLDEETKKLKSKYAEPLLLLQELFPDWKEEDLLSVLAE TEGNAETASLRIAEGHATQWGEVKKKSKDRSKKQEFSESTSSSTPAPEKHSSSSQRSSLSKHVPRGPKSERSVSSAASAP RSTRGPRKQPHTNGHSQSTENTTSRNTSEHSHTPTPAPAPSTTSSNTSSATPAPSLTWAALAASKPKPAPASTAPAAAPP ATATTHAQIESDSATITVKVPTSSTPPQESSQESTESVSVPTGPSSSNAAPTQTSASPAVAAAAPSPAPAAAAAPPAKLS WAAIAAPPPPPPKVTKPVAPAAPVAAAAPAAPAVEVATSTPTTTAPTAPTTTTTTEAATTEEVESAETASSVETAAPEPE TAAVEETVTESEPVSAPETTDVTPPGLEKAPESETAAPASEPVASESTESASASAAAVPAPLTSTPTAPASESQRPISIP SQPASEAQRSINSLPSQPAATAAAAGNHQGYSRRLNQDAPVVLPNSIGSRSISRLGSQYGSLNLAEDESSQDKSAEISAP TQPRSTVNEQQHQSQNVYQVQHPQSQSQTYGNYNRFNQRTNNYQTQSQQQQPQQQQPQQQAQQQAQQQAQQAQQAQQQQG QQLPKPYDNYGQNQFMYPGAHPNFNASYYADYGYGANDASRNAFSGYYGYPQHLQDALNRGIGGFDQSGIPQQSSRYGAE KPPVTAGSTNAASQSPATTAASPGITSASSGPTAGQYGQVPYYMNPYHYYYPFNPQAAQAAQFNSQNAFYKQPYYTGMDY RQHQPQQQTPQQASQQASQQQQGGQQQAAQQGQQQAGAAAGQNTLSGISDFLNREDKGAPGSPQTLVGNAQISGGPVQMH QTQTQPQNQYQPNMYSYAGYGQQQYTANRQWNSYN
GO term prediction
Biological Process
None predicted.
Molecular Function
GO:0005515 protein binding
Cellular Component
None predicted.