Protein

MIA_00703_1

Length
616 amino acids


Browser: contig01:2018095-2019946-

Protein function

EGGNOG:0PFXBFG06173.1MATE efflux family protein
SGD closest match:S000001074ERC1Ethionine resistance-conferring protein 1
CGD closest match:CAL0000200953orf19.6023Uncharacterized protein

Protein alignments

%idAln lengthE-value
MCA_05922_154.317%6370.0MCA_05922_1
A0A0J9X518_GEOCN49.836%6100.0Similar to Saccharomyces cerevisiae YHR032W ERC1 Member of the multi-drug and toxin extrusion (MATE) family of the multidrug/oligosaccharidyl-lipid/polysaccharide (MOP) exporter superfamily OS=Geotrichum candidum GN=BN980_GECA02s07380g PE=4 SV=1
A0A167D1V8_9ASCO51.961%6120.0Erc1p OS=Sugiyamaella lignohabitans GN=ERC1 PE=4 SV=1
UniRef50_A0A167D1V851.961%6120.0Erc1p n=2 Tax=Saccharomycetales TaxID=4892 RepID=A0A167D1V8_9ASCO
A0A1E3PIB2_9ASCO44.939%6522.64e-177MATE efflux family protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83146 PE=4 SV=1
A0A060T8Q2_BLAAD46.244%5991.68e-174ARAD1D09042p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D09042g PE=4 SV=1
Q6C7N2_YARLI54.670%4398.92e-154YALI0D26730p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D26730g PE=4 SV=1
A0A1E4TGI6_9ASCO47.510%4822.64e-152Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_44452 PE=4 SV=1
A0A1D8PCB5_CANAL47.930%4592.18e-142Uncharacterized protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.6023 PE=4 SV=1
ERC1_YEAST46.898%4039.07e-118Ethionine resistance-conferring protein 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ERC1 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0727

Protein family membership

Domains and repeats

None predicted.

Detailed signature matches

    1. PF01554 (MatE)
Unintegrated signatures no IPR
Unintegrated signatures
  1. TRANSMEMBRANE (Tran...)
  2. cd13132 (MATE_eukar...)
  3. mobidb-lite (disord...)

Residue annotation

  1. putative cation bi...

Protein sequence

>MIA_00703_1
MSIPIASPKTPVNVPHSHHAFSQSPSNAHIVYGSVGRSAFADPLHLSPVLSPPSNMEDNAFVVNPRQARLLAQEEADILN
HSNKPYKAPEHIHESISSETLISQNTETDPLISQEASSSHTYGSASSPQTQFSEDEQDSGTAQVMAISKAWDEAVDEGCA
ETSYAMEIRYLICNSCPLVITFLLQYSLTVASIFSVGHLGKTQLAAVSLASMTANITGFAMIQGLATCLDTLCAQAYGAG
NYALVGEYFQKCTLMVMACFAPVSILWLNAEPLIRLLVTHDDPALAPLATSYLRIVLVGVPGYIAFECGKRFVQAQGIYF
AATLVLFICAPINAFLNYHLVWSPVVGLGFIGAPLAVTITQWLMAILLFLYVRYIDGLKCWGGLSRQIFKHWGTMFKLAV
PGVIMIEAEFLAFEILTFAASRLGTTALAAQSVLATTSSLLYQIPFAMSIVASNRIANFVGAALPQNALIAKNVALAAAV
VFGIVDSAALYALRFNVGTAFSSDPDVVALVANSLIVLVFCTTVDAPGAVLGGVLRGFGRQAIGGYLNLFFYYAVAMPLG
LLLAFRYNYKLNGLWGGIFVALSCIDISEFFYVQQVDWQALVDEARSRQSLERIVP

GO term prediction

Biological Process

GO:0006855 drug transmembrane transport
GO:0055085 transmembrane transport

Molecular Function

GO:0015238 drug transmembrane transporter activity
GO:0015297 antiporter activity

Cellular Component

GO:0016020 membrane