Protein
MCA_05922_1
Length
620 amino acids
Gene name: ERC1
Description: Ethionine resistance-conferring protein 1
Browser: contigD:2775691-2777554+
RNA-seq: read pairs 1104, FPKM 22.0, percentile rank 43.9% (100% = highest expression)
Protein function
| Annotation: | ERC1 | Ethionine resistance-conferring protein 1 | |
|---|---|---|---|
| KEGG: | K03327 | TC.MATE | multidrug resistance protein, MATE family |
| EGGNOG: | 0PFXB | ERC1 | MATE efflux family protein |
| SGD closest match: | S000001074 | ERC1 | Ethionine resistance-conferring protein 1 |
| CGD closest match: | CAL0000182629 | orf19.6691 | Uncharacterized protein |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_00703_1 | 55.06% | 632 | 0.0 | MIA_00703_1 |
| A0A0J9X518_GEOCN | 52.44% | 595 | 0.0 | Similar to Saccharomyces cerevisiae YHR032W ERC1 Member of the multi-drug and toxin extrusion (MATE) family of the multidrug/oligosaccharidyl-lipid/polysaccharide (MOP) exporter superfamily OS=Geotrichum candidum GN=BN980_GECA02s07380g PE=4 SV=1 |
| A0A167D1V8_9ASCO | 50.42% | 599 | 0.0 | Erc1p OS=Sugiyamaella lignohabitans GN=ERC1 PE=4 SV=1 |
| UniRef50_A0A167D1V8 | 50.42% | 599 | 0.0 | Erc1p n=2 Tax=Saccharomycetales TaxID=4892 RepID=A0A167D1V8_9ASCO |
| A0A060T8Q2_BLAAD | 48.58% | 597 | 3e-172 | ARAD1D09042p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D09042g PE=4 SV=1 |
| A0A1E3PIB2_9ASCO | 47.12% | 590 | 2e-166 | MATE efflux family protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83146 PE=4 SV=1 |
| A0A1E4TGI6_9ASCO | 49.05% | 473 | 5e-148 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_44452 PE=4 SV=1 |
| Q6C7N2_YARLI | 49.40% | 498 | 9e-145 | YALI0D26730p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D26730g PE=4 SV=1 |
| Q59R29_CANAL | 41.79% | 615 | 2e-133 | Uncharacterized protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.6691 PE=4 SV=1 |
| ERC1_YEAST | 48.62% | 434 | 7e-131 | Ethionine resistance-conferring protein 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ERC1 PE=1 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0135
Protein family membership
- Multi antimicrobial extrusion protein (IPR002528)
Domains and repeats
None predicted.
Detailed signature matches
no IPR
Unintegrated signatures
-
CYTOPLASMIC_D... (C...)
-
NON_CYTOPLASM... (N...)
-
-
TRANSMEMBRANE (Tran...)
-
cd13132 (MATE_eukar...)
-
mobidb-lite (disord...)
Residue annotation
-
putative cation bi...
Protein sequence
>MCA_05922_1 MAPLDIPSSPNNKLKPKKSVDVPFHHGFSQSPSNAHIVVGSVGRSAIADPHDFHLPSKIRRLSISAADALSPLLGTTEEN DEDVFSDADNRFIVTPQQAKRLADEERELLERSGVSPDTHANYGATGNSSGDTETMAEEEQEVLNISKVWDEAVSQGQVS TDLVTEFKFILKNSAPLMLTFLLQCSLTVASIFTVGHLGKAELAAASLGSMTANITGFALIQGLATCLDTLCAQSYGAGQ FHQVGGYFQKGTLMIFTCFFPVGVLWVFSRPLLRLFVGSDGNEETEALISLAATYLRIVLIGSPGYILFECGKRFVQAQG IFHASTYVLVIVAPINALLNYALVWTPQLKLGFIGAPIAVAIAQWMMAILLFLYVYFIDGKKCWDGFNKNVFSNWLVMFK LAIPGVIMIEAEFLAFEILTLAASRLGTTPLAAQSIITTTSSLLYQVPFAMSIAASTRVANFIGASLGDAAKITKRVSMI CMFTIGFLNSLALYIFRYHIGNLFSNDPEVVHLVAITIPALVMCAFFDAPNAVLGGILRGLGRQSIGGYLNLFAYYVVGI PISLITTFKFDMGLKGLWIGIGIGLMIVDLFEFLYVEYVDFDKVVEESLERQRMERIVQV
GO term prediction
Biological Process
GO:0006855 drug transmembrane transport
GO:0055085 transmembrane transport
Molecular Function
GO:0015238 drug transmembrane transporter activity
GO:0015297 antiporter activity
Cellular Component
GO:0016020 membrane