Protein
MIA_00698_1
Length
569 amino acids
Browser: contig01:2004061-2005771-
Protein function
| EGGNOG: | 0PFXB | FG06173.1 | MATE efflux family protein |
|---|---|---|---|
| SGD closest match: | S000001074 | ERC1 | Ethionine resistance-conferring protein 1 |
| CGD closest match: | CAL0000200953 | orf19.6023 | Uncharacterized protein |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MCA_05922_1 | 47.87% | 445 | 1e-126 | MCA_05922_1 |
| A0A167D1V8_9ASCO | 39.71% | 554 | 7e-115 | Erc1p OS=Sugiyamaella lignohabitans GN=ERC1 PE=4 SV=1 |
| UniRef50_A0A167D1V8 | 39.71% | 554 | 2e-111 | Erc1p n=2 Tax=Saccharomycetales TaxID=4892 RepID=A0A167D1V8_9ASCO |
| A0A0J9X518_GEOCN | 43.24% | 414 | 1e-111 | Similar to Saccharomyces cerevisiae YHR032W ERC1 Member of the multi-drug and toxin extrusion (MATE) family of the multidrug/oligosaccharidyl-lipid/polysaccharide (MOP) exporter superfamily OS=Geotrichum candidum GN=BN980_GECA02s07380g PE=4 SV=1 |
| A0A1E3PII8_9ASCO | 41.06% | 414 | 2e-99 | MATE efflux family protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_51818 PE=4 SV=1 |
| A0A060T8Q2_BLAAD | 43.07% | 397 | 4e-98 | ARAD1D09042p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D09042g PE=4 SV=1 |
| A0A1E4TGI6_9ASCO | 40.53% | 412 | 5e-91 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_44452 PE=4 SV=1 |
| Q6C4J1_YARLI | 39.16% | 429 | 2e-89 | YALI0E26345p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E26345g PE=4 SV=1 |
| A0A1D8PCB5_CANAL | 40.93% | 430 | 2e-88 | Uncharacterized protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.6023 PE=4 SV=1 |
| ERC1_YEAST | 38.68% | 393 | 9e-75 | Ethionine resistance-conferring protein 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ERC1 PE=1 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.2829
Protein family membership
- Multi antimicrobial extrusion protein (IPR002528)
Domains and repeats
None predicted.
Detailed signature matches
no IPR
Unintegrated signatures
-
CYTOPLASMIC_D... (C...)
-
NON_CYTOPLASM... (N...)
-
-
TRANSMEMBRANE (Tran...)
-
cd13132 (MATE_eukar...)
Residue annotation
-
putative cation bi...
Protein sequence
>MIA_00698_1 MKNTNKSPVLKALLQSTGNTLSVTDYGSIDQSLIDDSTCINRETPLHSTPEENVLIFTQNPASPLQTSEQRILVREKSSR SRQKSPFPSPPNIFANIVPDESDCDSISDSESTARFFRTDSKALAVTYIMEIKSILISAGPLILTLLLQNTLTIASIFFV GHLGKSYLAAVSLASMMANITGMAFIQGLATCLDVLCADAFHSRNFKLVGEYVYKCILMILVCYFPIGILWYYSKPLFSF ISPKDDPFISYLAAEYLRVALIGIPGYICFECGKRLVQAQGMHHLSSNILFICAPINLALTYILVWYPGVSVGYIGSAIA ISITQWLMAFLLFGYSWYSCGFKKWVSFSGNLFKDWGSMIKLSFTNLVMVEMEIFAFEVFIFCASLLGTVEVATQSIIFA TSSTFYQISLAVSIISSHRISCYITAASSKNVKVVKNCSLIISIFVGLAISAFIYFGRYIIVSIFSDDIEVKNLFIQSAS SLAFMAFADAPSAVLSGILRGLGRSHITGYLNLFFYYFQALPLAILLTFLWGFSIAGFSVSMGISLVLIGVCEFGYIQMI DLSLLVEQF
GO term prediction
Biological Process
GO:0006855 drug transmembrane transport
GO:0055085 transmembrane transport
Molecular Function
GO:0015238 drug transmembrane transporter activity
GO:0015297 antiporter activity
Cellular Component
GO:0016020 membrane