Protein

MIA_00665_1

Length
683 amino acids

Browser: contig01:1900966-1903018-

Protein function

EGGNOG:0PFCWPGUG_03578pseudouridine synthase
SGD closest match:S000005769PUS7Multisubstrate pseudouridine synthase 7
CGD closest match:CAL0000177714PUS7Pseudouridine synthase

Protein alignments

%idAln lengthE-value
MCA_00445_167.947%6770.0MCA_00445_1
A0A0J9X8V1_GEOCN61.725%6610.0Similar to Saccharomyces cerevisiae YOR243C PUS7 Pseudouridine synthase, catalyzes pseudouridylation at positions 35 and 56 in U2 snRNA, position 50 in 5S rRNA,position 13 in cytoplasmic tRNA OS=Geotrichum candidum GN=BN980_GECA05s05059g PE=4 SV=1
A0A060T788_BLAAD59.133%6460.0ARAD1B21582p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B21582g PE=4 SV=1
A0A167D5T6_9ASCO56.213%6760.0Pseudouridine synthase PUS7 OS=Sugiyamaella lignohabitans GN=PUS7 PE=4 SV=1
UniRef50_A0A167D5T656.213%6760.0Pseudouridine synthase PUS7 n=3 Tax=Saccharomycetales TaxID=4892 RepID=A0A167D5T6_9ASCO
A0A1E3PPM4_9ASCO48.711%6980.0tRNA pseudouridine synthase D OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_81800 PE=4 SV=1
Q6CAL7_YARLI52.951%6270.0YALI0D01628p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D01628g PE=4 SV=1
PUS7_YEAST47.320%6530.0Multisubstrate pseudouridine synthase 7 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PUS7 PE=1 SV=1
A0A1E4TK59_9ASCO42.373%6491.77e-168Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_82618 PE=4 SV=1
A0A1D8PIN8_CANAL40.473%7192.90e-165Pseudouridine synthase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=PUS7 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.2120

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 600 683

Detailed signature matches

  1. Family IPR001656
    Pseudouridine synthase, TruD
    1. TIGR00094
    2. PF01142 (TruD)
  2. Domain IPR020103
    Pseudouridine synthase, catalytic domain
    1. SSF55120 (Pseudouri...)
  3. Domain IPR011760
    Pseudouridine synthase, TruD, insertion domain
    1. PS50984 (TRUD)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.30.23...
  2. PIRSF037016 (Pseudo...)
  3. cd02576 (PseudoU_sy...)
  4. mobidb-lite (disord...)

Residue annotation

  1. probable active si...

Protein sequence

>MIA_00665_1
MPPTRSAESAFESENSSVKRVKVDDDKATEQISTEQSKPLADKPVVKPYSAPNKGISEVDVGITEFLSPELKGFKGILKQ
RYSDFLVNEIDKDGNVIHLTDTGFSDKRDRRKERREEQRSADDSKTETQDQDAKPTRKLFELTPENREKLINLLDEKTVD
DMVALLTNGSKVVTETPIDDKDDRTVIHKTVREAFESRLETRTTPENTFIITLASGSQFRSKADRRGKSSVGAANANIGP
RKNFLHFTLYKENKETMQVAHLLSKFLRIPPKTFTYAGTKDRRGVTVQRACVSKLPAERLNGLNKTLRGIKLGGFKYEDN
QLKLGDLKGNEFYITIRNVDEPDHEVINASLSSLRDNGFINYYGMQRFGTFSISTHTIGVHILNSDWETAVKSILSPQEL
VVPESVEARKVWSETNDAKKALLLMPRKCVAEHSILEVLSDTPNSYFNAIMRIPRNLRIMYGHAYQSYIWNTVASERIKR
FGTKIMEGDLVLVDEADKTSAQTQEAEEDGEDFGEGDVKTDIFIRARPVTKEEIESGKKTIFDVVLPTPGFDIRYPENEL
KQVYIDQMKKDGLDPDNMRRNIREFSFAGSYRHILSRPDLVEWWIRKYDDDAEQMIKTDLDLLQEGLSEDKRIVENSDEG
SKIAVLLKIQLGTSQYATMALREMMKLDTKRRGEGLDVRKNED

GO term prediction

Biological Process

GO:0001522 pseudouridine synthesis
GO:0009451 RNA modification

Molecular Function

GO:0003723 RNA binding
GO:0009982 pseudouridine synthase activity

Cellular Component

None predicted.