Protein

MIA_00642_1

Length
579 amino acids

Browser: contig01:1847501-1849510+

Protein function

EGGNOG:0PIG6FG04413.1Sphingosine-1-phosphate lyase
SGD closest match:S000002702DPL1Sphingosine-1-phosphate lyase
CGD closest match:CAL0000198326orf19.6951Sphinganine-1-phosphate aldolase

Protein alignments

%idAln lengthE-value
MCA_00550_169.735%5650.0MCA_00550_1
A0A060T3S4_BLAAD62.915%5420.0ARAD1C36014p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C36014g PE=3 SV=1
A0A0J9XB84_GEOCN66.855%5310.0Similar to Saccharomyces cerevisiae YDR294C DPL1 Dihydrosphingosine phosphate lyase OS=Geotrichum candidum GN=BN980_GECA08s03453g PE=3 SV=1
A0A161HH66_9ASCO69.136%4860.0Sphinganine-1-phosphate aldolase DPL1 OS=Sugiyamaella lignohabitans GN=DPL1 PE=3 SV=1
A0A1E3PFN9_9ASCO59.704%5410.0PLP-dependent transferase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_47502 PE=3 SV=1
SGPL_YEAST58.118%5420.0Sphingosine-1-phosphate lyase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=DPL1 PE=1 SV=1
UniRef50_Q0556758.118%5420.0Sphingosine-1-phosphate lyase n=78 Tax=Saccharomycetales TaxID=4892 RepID=SGPL_YEAST
A0A1D8PJQ9_CANAL55.064%5430.0Sphinganine-1-phosphate aldolase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.6951 PE=3 SV=1
Q6C4B5_YARLI64.667%4500.0YALI0E28237p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E28237g PE=3 SV=1
A0A1E4TG69_9ASCO51.554%5473.56e-178Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_31548 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1617

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 579

Detailed signature matches

  1. Family IPR002129
    Pyridoxal phosphate-dependent decarboxylase
    1. PF00282 (Pyridoxal_deC)
  2. Domain IPR015424
    Pyridoxal phosphate-dependent transferase
    1. SSF53383 (PLP-depen...)
  3. Domain IPR015421
    Pyridoxal phosphate-dependent transferase, major region, subdomain 1
    1. G3DSA:3.40.64...
  4. Domain IPR015422
    Pyridoxal phosphate-dependent transferase, subdomain 2
    1. G3DSA:3.90.11...
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. NON_CYTOPLASM... (N...)
  3. TMhelix
  4. TRANSMEMBRANE (Tran...)

Protein sequence

>MIA_00642_1
MTLLSSQSDCVAVKKAQEYLELALQHPLAVDLLDQPITKELLSYYENASPFELFRDLVFAYLAIKYFNKALGHVWRYGPI
GTLLLIWSTIATYFFKKFQQIPFVKKKVDQEVTKVLDKIEDDLIDRSLTYYTKLPESGWSPDKVTEELEKNTQMKHTKWE
EGRVSGAVYHGGQDILSIQAKAYSLYSVANQLHPDVFPAVRKMESEVVAMVLKLYNAPEGAEGTSTSGGTESLLLACLAA
REKAFRERGITEPEIIAPETIHAGFDKAAYYFKMKLVHAPLDPKTFQVDLKAVKRLINKNTVLLAGSAPNFPHGIIDNIQ
GLSKLALRYKIPLHVDACLGSFIVPFLDKAGFGKGVPLFDFRVPGVTSISCDTHKYGFAPKGSSIIMYRTNEMRQYQYYI
TAKWTGGLYASPTLAGSRPGALMVGCWATLMAMGEKGYTESCREIVGAARRIKAFAREDPDLKELLDVIGEPLGSVVSFK
SSAVSVYALADQMNKKGWHLNALQKPAAIHIAVTRLTVPVVDEFLSDLKATARELKENNVTPESSKSDTTVLYGVAGSVK
TVGVADRLAAGFLDCLYKV

GO term prediction

Biological Process

GO:0019752 carboxylic acid metabolic process

Molecular Function

GO:0003824 catalytic activity
GO:0016831 carboxy-lyase activity
GO:0030170 pyridoxal phosphate binding

Cellular Component

None predicted.