Protein

MCA_00550_1

Length
567 amino acids

Gene name: DPL1

Description: Sphingosine-1-phosphate lyase

Browser: contigA:1716479-1718543+

RNA-seq: read pairs 3844, FPKM 83.6, percentile rank 76.0% (100% = highest expression)

Protein function

Annotation:DPL1Sphingosine-1-phosphate lyase
KEGG:K01634SGPL1 sphinganine-1-phosphate aldolase [EC:4.1.2.27]
EGGNOG:0PIG6FG04413.1Sphingosine-1-phosphate lyase
SGD closest match:S000002702DPL1Sphingosine-1-phosphate lyase
CGD closest match:CAL0000198326orf19.6951Sphinganine-1-phosphate aldolase

Protein alignments

%idAln lengthE-value
MIA_00642_169.73%5650.0MIA_00642_1
A0A0J9XB84_GEOCN66.86%5220.0Similar to Saccharomyces cerevisiae YDR294C DPL1 Dihydrosphingosine phosphate lyase OS=Geotrichum candidum GN=BN980_GECA08s03453g PE=3 SV=1
A0A161HH66_9ASCO70.56%4790.0Sphinganine-1-phosphate aldolase DPL1 OS=Sugiyamaella lignohabitans GN=DPL1 PE=3 SV=1
A0A060T3S4_BLAAD60.30%5340.0ARAD1C36014p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C36014g PE=3 SV=1
A0A1E3PFN9_9ASCO61.60%5390.0PLP-dependent transferase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_47502 PE=3 SV=1
Q6C4B5_YARLI66.22%4470.0YALI0E28237p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E28237g PE=3 SV=1
UniRef50_Q6C4B566.22%4470.0YALI0E28237p n=2 Tax=Yarrowia lipolytica TaxID=4952 RepID=Q6C4B5_YARLI
A0A1E4TG69_9ASCO54.43%5530.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_31548 PE=3 SV=1
SGPL_YEAST56.53%5360.0Sphingosine-1-phosphate lyase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=DPL1 PE=1 SV=1
A0A1D8PJQ9_CANAL55.26%5230.0Sphinganine-1-phosphate aldolase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.6951 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1289

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 567

Detailed signature matches

  1. Family IPR002129
    Pyridoxal phosphate-dependent decarboxylase
    1. PF00282 (Pyridoxal_deC)
  2. Domain IPR015424
    Pyridoxal phosphate-dependent transferase
    1. SSF53383 (PLP-depen...)
  3. Domain IPR015421
    Pyridoxal phosphate-dependent transferase, major region, subdomain 1
    1. G3DSA:3.40.64...
  4. Domain IPR015422
    Pyridoxal phosphate-dependent transferase, subdomain 2
    1. G3DSA:3.90.11...

Protein sequence

>MCA_00550_1
MSYLKTNILYSHASPYLDIAQEWYTQNAEPIISQYIEEHECAQTAIKYFQNSSIWQNIRDLVFALFVLKYVNIGLKYISR
HGLFGSVVALYTCFMKYFFTKFQQLPFVKSKVDKEVGKVLEKIESELIDRSIEYYTTVPKTGWSNEEVSNILIKGTKMDH
TKWEEGRVSGAVYHGGQEILDLQAKAYSLYSVANQLHPDVFPAVRKMESEVVSMVLGLYNAPEGAVGTSTSGGTESLLLA
CLSAREKAYRERGVTEPEIIAPTTIHAGFDKAAYYFKMKLIHAPLDPKTFKNTILLAGSAPNFPHGIIDDIEGLSKLALK
YKLPLHVDACLGSFIVPFLTKAGFTDIPLFDFRVPGVTSISCDTHKYGFAPKGSSIIMYRNNQLRQYQYFVTADWTGGLY
ASPTLAGSRPGALMAGCWATLMKIGVDGYTQSCKEIVSTARKIKTTVIEEIPELQVIGNPLGSVVAFKSDVIAIYDLADV
MNKKGWHLNALQKPAAIHIACTRLTVPVVDDLLADLKKSVKELVAAGSNAKDAKSDTSVLYGVAGSVKTVGVADRLAAGF
LDCLYKV

GO term prediction

Biological Process

GO:0019752 carboxylic acid metabolic process

Molecular Function

GO:0003824 catalytic activity
GO:0016831 carboxy-lyase activity
GO:0030170 pyridoxal phosphate binding

Cellular Component

None predicted.