MIA_00611_1
Browser: contig01:1755150-1758342-
Protein function
EGGNOG: | 0PGN9 | ILS1 | Isoleucyl-tRNA synthetase |
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SGD closest match: | S000000172 | ILS1 | Isoleucine--tRNA ligase, cytoplasmic |
CGD closest match: | CAL0000188404 | ILS1 | Isoleucine--tRNA ligase |
Protein alignments
%id | Aln length | E-value | ||
---|---|---|---|---|
MCA_00552_1 | 87.394% | 1063 | 0.0 | MCA_00552_1 |
A0A0J9XBZ9_GEOCN | 80.715% | 1063 | 0.0 | Similar to Saccharomyces cerevisiae YBL076C ILS1 Cytoplasmic isoleucine-tRNA synthetase, target of the G1-specific inhibitor reveromycin A OS=Geotrichum candidum GN=BN980_GECA08s04993g PE=3 SV=1 |
A0A060T467_BLAAD | 74.506% | 1063 | 0.0 | ARAD1C41998p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C41998g PE=3 SV=1 |
A0A1E3PRI7_9ASCO | 73.714% | 1069 | 0.0 | Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_48695 PE=3 SV=1 |
A0A167C7F2_9ASCO | 75.811% | 1017 | 0.0 | Isoleucine--tRNA ligase ILS1 OS=Sugiyamaella lignohabitans GN=ILS1 PE=4 SV=1 |
SYIC_YEAST | 68.293% | 1066 | 0.0 | Isoleucine--tRNA ligase, cytoplasmic OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ILS1 PE=1 SV=1 |
UniRef50_P09436 | 68.293% | 1066 | 0.0 | Isoleucine--tRNA ligase, cytoplasmic n=454 Tax=Fungi TaxID=4751 RepID=SYIC_YEAST |
Q6CIA2_YARLI | 66.853% | 1071 | 0.0 | YALI0A00264p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_A00264g PE=3 SV=1 |
A0A1E4TCQ3_9ASCO | 65.799% | 1076 | 0.0 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_140646 PE=3 SV=1 |
Q59RI1_CANAL | 65.205% | 1072 | 0.0 | Isoleucine--tRNA ligase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ILS1 PE=3 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0183
Protein family membership
- Isoleucine-tRNA ligase (IPR002301)
- Isoleucine-tRNA ligase, type 2 (IPR023586)
Domains and repeats
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Domain
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Domain
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Domain
Detailed signature matches
Residue annotation
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active site cd00818
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HIGH motif cd00818
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KMSKS motif cd00818
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tRNA binding surfa...
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anticodon binding ...
Protein sequence
>MIA_00611_1 MDFPKAEEQVLEFWNEIDAFQTSLKLSEGRPVYNFYDGPPFATGTPHYGHILASTVKDIIPRYAHMTGHYVERRFGWDTH GLPVEYEIDKKLGITGKQDVMDMGIDKYNAECRAIVMRYASEWRSTIGRMGRWIDFDNDYKTLYPTFMETIWWVFKQLFD KNSVYRGYRVMPYSTGLTTPLSNFEAQQNYKEVLDPAITIAFPLVDDPDTSFVAWTTTPWTLPSNLALCVNPDYEYVKIH DEKTGKNYILLEKLLTTLYKNPKKEKLKVVEKYKGSDLKGMKYVPLFNYFYDEFKDHAFRVLNDTYVKDDSGTGIVHQAP AFGEDDYAVCVAHGVISEDRAPPNPVDDTGKFTSQVPDWEGVYVKDADRKIIKYLKEQGRILVDAQLRHSYPFCWRSDTP LLYRTVPAWFVRIKEIIPNMLKHIDESHWVPNAIKEGRFANWIKNARDWNISRNRYWGTPIPLWVSDDLEEIVCIGSIEE LRELSGVQDITDLHRENIDHITIPSKQGKGTLKRIEEVFDCWFESGSMPYASQHYPFENAEKFKKGFPADFISEGLDQTR GWFYTLVVLGTHLFDVSPFKNCIVSGIVLAADGKKMSKRLKNYPDPNLILDKYGADALRLYLINSPVLRAETLKFKEEGV KEVVSKVLLPWWNSYKFWEGQVALLKKLENIDFKYDPNLRSENVMDKWILASLQTLIGYIHEEMGQYRLYNVVPGLLKLI EDLTNWYIRLNRSRLKGENGVDDTIKALNTLFEALYVLVRAMAPFTPFLAETIYKNLKVAIPENLHEGDDRSVHFLAYPV VRKELIDDKTELAVNRMRRVIELGRNIRERKTISLKVPLRTFVVIHHDKGYLEDLESLKSYIIDELNIRDLILTSEEEKF DVEYKAQADWPVLGKKLRKDIAKVKKALPGLTSDQVQGYLKNKKIEIDGIELVEGDLTVIRGVSDKAVQNGQEVNTDQDV LVIMDITVDEDLKSEANAREFINRVQRYRKKLNLLATDEVQVEVEITKDTCGLSECLKNHKDIIEKTLRRPLQTFGESTE GENLGEEDQEIGDTLFKLRLLKL
GO term prediction
Biological Process
GO:0006418 tRNA aminoacylation for protein translation
GO:0006428 isoleucyl-tRNA aminoacylation
Molecular Function
GO:0000049 tRNA binding
GO:0000166 nucleotide binding
GO:0002161 aminoacyl-tRNA editing activity
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004822 isoleucine-tRNA ligase activity
GO:0005524 ATP binding
Cellular Component
GO:0005737 cytoplasm