MCA_00552_1

Protein

Length

1,063 amino acids

Gene name: ILS1

Description: Isoleucine--tRNA ligase, cytoplasmic

Browser: contigA:1720796-1723988+

RNA-seq: read pairs 8841, FPKM 102.7, percentile rank 79.2% (100% = highest expression)

Protein function

Annotation:		ILS1	Isoleucine--tRNA ligase, cytoplasmic
KEGG:	K01870	IARS	isoleucyl-tRNA synthetase [EC:6.1.1.5]
EGGNOG:	0PGN9	ILS1	Isoleucyl-tRNA synthetase
SGD closest match:	S000000172	ILS1	Isoleucine--tRNA ligase, cytoplasmic
CGD closest match:	CAL0000188404	ILS1	Isoleucine--tRNA ligase

Protein alignments

	%id	Aln length
MIA_00611_1	87.39%	1063	MIA_00611_1
A0A0J9XBZ9_GEOCN	80.06%	1063	Similar to Saccharomyces cerevisiae YBL076C ILS1 Cytoplasmic isoleucine-tRNA synthetase, target of the G1-specific inhibitor reveromycin A OS=Geotrichum candidum GN=BN980_GECA08s04993g PE=3 SV=1
A0A060T467_BLAAD	74.13%	1063	ARAD1C41998p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C41998g PE=3 SV=1
A0A1E3PRI7_9ASCO	72.95%	1072	Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_48695 PE=3 SV=1
A0A167C7F2_9ASCO	74.93%	1017	Isoleucine--tRNA ligase ILS1 OS=Sugiyamaella lignohabitans GN=ILS1 PE=4 SV=1
SYIC_YEAST	68.05%	1064	Isoleucine--tRNA ligase, cytoplasmic OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ILS1 PE=1 SV=1
UniRef50_P09436	68.05%	1064	Isoleucine--tRNA ligase, cytoplasmic n=454 Tax=Fungi TaxID=4751 RepID=SYIC_YEAST
Q6CIA2_YARLI	66.48%	1071	YALI0A00264p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_A00264g PE=3 SV=1
A0A1E4TCQ3_9ASCO	66.20%	1074	Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_140646 PE=3 SV=1
Q59RI1_CANAL	65.11%	1072	Isoleucine--tRNA ligase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ILS1 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0131

Protein family membership

Isoleucine-tRNA ligase (IPR002301)
- Isoleucine-tRNA ligase, type 2 (IPR023586)

Domains and repeats

Domain
10 - 633
Aminoacyl-tRNA synthetase, class Ia (IPR002300)
Domain
32 - 205
Rossmann-like alpha/beta/alpha sandwich fold (IPR014729)
Domain
192 - 391
Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain (IPR009008)
580 - 901
Aminoacyl-tRNA synthetase, class Ia, anticodon-binding (IPR009080)
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding (IPR013155)
Isoleucyl tRNA synthetase type 2, anticodon-binding domain (IPR033709)

1 100 200 300 400 500 600 700 800 900 1000 1063

Detailed signature matches

IPR002301

Isoleucine-tRNA ligase
1. TIGR00392
  
  2 - 853
  
  TIGRFAMs
  TIGR00392 (TIGR00392)
2. PR00984 (TRNASYNTHILE)
  
  389 - 404
  
  PRINTS
  PR00984 (TRNASYNTHILE)
  
  514 - 527
  
  PRINTS
  PR00984 (TRNASYNTHILE)
  
  554 - 563
  
  PRINTS
  PR00984 (TRNASYNTHILE)
  
  33 - 44
  
  PRINTS
  PR00984 (TRNASYNTHILE)
  
  213 - 236
  
  PRINTS
  PR00984 (TRNASYNTHILE)
IPR023586

Isoleucine-tRNA ligase, type 2
1. MF_02003 (Ile_tRNA_...)
  
  1 - 1,062
  
  HAMAP
  MF_02003 (Ile_tRNA_synth_type2)
IPR002300

Aminoacyl-tRNA synthetase, class Ia
1. PF00133 (tRNA-synt_1)
  
  10 - 633
  
  Pfam
  PF00133 (tRNA-synt_1)
IPR014729

Rossmann-like alpha/beta/alpha sandwich fold
1. G3DSA:3.40.50...
  
  32 - 205
  
  GENE3D
  G3DSA:3.40.50.620 (G3DSA:3.40.50.620)
IPR009008

Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain
1. SSF50677 (ValRS/Ile...)
  
  192 - 391
  
  SUPERFAMILY
  SSF50677 (ValRS/IleRS/LeuRS editing domain)
IPR009080

Aminoacyl-tRNA synthetase, class Ia, anticodon-binding
1. G3DSA:1.10.73...
  
  580 - 834
  
  GENE3D
  G3DSA:1.10.730.10 (G3DSA:1.10.730.10)
2. SSF47323 (Anticodon...)
  
  650 - 901
  
  SUPERFAMILY
  SSF47323 (Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases)
IPR013155

Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding
1. PF08264 (Anticodon_1)
  
  686 - 841
  
  Pfam
  PF08264 (Anticodon_1)
IPR033709

Isoleucyl tRNA synthetase type 2, anticodon-binding domain
1. cd07961 (Anticodon_...)
  
  635 - 825
  
  CDD
  cd07961 (Anticodon_Ia_Ile_ABEc)
IPR001412

Aminoacyl-tRNA synthetase, class I, conserved site
1. PS00178 (AA_TRNA_LI...)
  
  40 - 51
  
  PROSITE patterns
  PS00178 (AA_TRNA_LIGASE_I)

no IPR

Unintegrated signatures

G3DSA:3.90.74...

206 - 487

GENE3D
G3DSA:3.90.740.10 (G3DSA:3.90.740.10)
SSF52374 (Nucleotid...)

2 - 190

SUPERFAMILY
SSF52374 (Nucleotidylyl transferase)

391 - 643

SUPERFAMILY
SSF52374 (Nucleotidylyl transferase)
cd00818 (IleRS_core)

31 - 635

CDD
cd00818 (IleRS_core)

Residue annotation

active site cd00818

39P

active site
39P, 40P, 41F, 47H, 49G, 50H, 53A, 416I, 522W, 525S, 554E, 555G, 556L, 557D, 558Q, 560R, 562W, 585S, 586G, 587I, 588V, 589L, 593G, 594K, 595K, 596M, 597S, 598K, 632T
CDD
cd00818 (IleRS_core)

40P

active site
39P, 40P, 41F, 47H, 49G, 50H, 53A, 416I, 522W, 525S, 554E, 555G, 556L, 557D, 558Q, 560R, 562W, 585S, 586G, 587I, 588V, 589L, 593G, 594K, 595K, 596M, 597S, 598K, 632T
CDD
cd00818 (IleRS_core)

41F

active site
39P, 40P, 41F, 47H, 49G, 50H, 53A, 416I, 522W, 525S, 554E, 555G, 556L, 557D, 558Q, 560R, 562W, 585S, 586G, 587I, 588V, 589L, 593G, 594K, 595K, 596M, 597S, 598K, 632T
CDD
cd00818 (IleRS_core)

47H

active site
39P, 40P, 41F, 47H, 49G, 50H, 53A, 416I, 522W, 525S, 554E, 555G, 556L, 557D, 558Q, 560R, 562W, 585S, 586G, 587I, 588V, 589L, 593G, 594K, 595K, 596M, 597S, 598K, 632T
CDD
cd00818 (IleRS_core)

49G

active site
39P, 40P, 41F, 47H, 49G, 50H, 53A, 416I, 522W, 525S, 554E, 555G, 556L, 557D, 558Q, 560R, 562W, 585S, 586G, 587I, 588V, 589L, 593G, 594K, 595K, 596M, 597S, 598K, 632T
CDD
cd00818 (IleRS_core)

50H

active site
39P, 40P, 41F, 47H, 49G, 50H, 53A, 416I, 522W, 525S, 554E, 555G, 556L, 557D, 558Q, 560R, 562W, 585S, 586G, 587I, 588V, 589L, 593G, 594K, 595K, 596M, 597S, 598K, 632T
CDD
cd00818 (IleRS_core)

53A

active site
39P, 40P, 41F, 47H, 49G, 50H, 53A, 416I, 522W, 525S, 554E, 555G, 556L, 557D, 558Q, 560R, 562W, 585S, 586G, 587I, 588V, 589L, 593G, 594K, 595K, 596M, 597S, 598K, 632T
CDD
cd00818 (IleRS_core)

416I

active site
39P, 40P, 41F, 47H, 49G, 50H, 53A, 416I, 522W, 525S, 554E, 555G, 556L, 557D, 558Q, 560R, 562W, 585S, 586G, 587I, 588V, 589L, 593G, 594K, 595K, 596M, 597S, 598K, 632T
CDD
cd00818 (IleRS_core)

522W

active site
39P, 40P, 41F, 47H, 49G, 50H, 53A, 416I, 522W, 525S, 554E, 555G, 556L, 557D, 558Q, 560R, 562W, 585S, 586G, 587I, 588V, 589L, 593G, 594K, 595K, 596M, 597S, 598K, 632T
CDD
cd00818 (IleRS_core)

525S

active site
39P, 40P, 41F, 47H, 49G, 50H, 53A, 416I, 522W, 525S, 554E, 555G, 556L, 557D, 558Q, 560R, 562W, 585S, 586G, 587I, 588V, 589L, 593G, 594K, 595K, 596M, 597S, 598K, 632T
CDD
cd00818 (IleRS_core)

554E

active site
39P, 40P, 41F, 47H, 49G, 50H, 53A, 416I, 522W, 525S, 554E, 555G, 556L, 557D, 558Q, 560R, 562W, 585S, 586G, 587I, 588V, 589L, 593G, 594K, 595K, 596M, 597S, 598K, 632T
CDD
cd00818 (IleRS_core)

555G

active site
39P, 40P, 41F, 47H, 49G, 50H, 53A, 416I, 522W, 525S, 554E, 555G, 556L, 557D, 558Q, 560R, 562W, 585S, 586G, 587I, 588V, 589L, 593G, 594K, 595K, 596M, 597S, 598K, 632T
CDD
cd00818 (IleRS_core)

556L

active site
39P, 40P, 41F, 47H, 49G, 50H, 53A, 416I, 522W, 525S, 554E, 555G, 556L, 557D, 558Q, 560R, 562W, 585S, 586G, 587I, 588V, 589L, 593G, 594K, 595K, 596M, 597S, 598K, 632T
CDD
cd00818 (IleRS_core)

557D

active site
39P, 40P, 41F, 47H, 49G, 50H, 53A, 416I, 522W, 525S, 554E, 555G, 556L, 557D, 558Q, 560R, 562W, 585S, 586G, 587I, 588V, 589L, 593G, 594K, 595K, 596M, 597S, 598K, 632T
CDD
cd00818 (IleRS_core)

558Q

active site
39P, 40P, 41F, 47H, 49G, 50H, 53A, 416I, 522W, 525S, 554E, 555G, 556L, 557D, 558Q, 560R, 562W, 585S, 586G, 587I, 588V, 589L, 593G, 594K, 595K, 596M, 597S, 598K, 632T
CDD
cd00818 (IleRS_core)

560R

active site
39P, 40P, 41F, 47H, 49G, 50H, 53A, 416I, 522W, 525S, 554E, 555G, 556L, 557D, 558Q, 560R, 562W, 585S, 586G, 587I, 588V, 589L, 593G, 594K, 595K, 596M, 597S, 598K, 632T
CDD
cd00818 (IleRS_core)

562W

active site
39P, 40P, 41F, 47H, 49G, 50H, 53A, 416I, 522W, 525S, 554E, 555G, 556L, 557D, 558Q, 560R, 562W, 585S, 586G, 587I, 588V, 589L, 593G, 594K, 595K, 596M, 597S, 598K, 632T
CDD
cd00818 (IleRS_core)

585S

active site
39P, 40P, 41F, 47H, 49G, 50H, 53A, 416I, 522W, 525S, 554E, 555G, 556L, 557D, 558Q, 560R, 562W, 585S, 586G, 587I, 588V, 589L, 593G, 594K, 595K, 596M, 597S, 598K, 632T
CDD
cd00818 (IleRS_core)

586G

active site
39P, 40P, 41F, 47H, 49G, 50H, 53A, 416I, 522W, 525S, 554E, 555G, 556L, 557D, 558Q, 560R, 562W, 585S, 586G, 587I, 588V, 589L, 593G, 594K, 595K, 596M, 597S, 598K, 632T
CDD
cd00818 (IleRS_core)

587I

active site
39P, 40P, 41F, 47H, 49G, 50H, 53A, 416I, 522W, 525S, 554E, 555G, 556L, 557D, 558Q, 560R, 562W, 585S, 586G, 587I, 588V, 589L, 593G, 594K, 595K, 596M, 597S, 598K, 632T
CDD
cd00818 (IleRS_core)

588V

active site
39P, 40P, 41F, 47H, 49G, 50H, 53A, 416I, 522W, 525S, 554E, 555G, 556L, 557D, 558Q, 560R, 562W, 585S, 586G, 587I, 588V, 589L, 593G, 594K, 595K, 596M, 597S, 598K, 632T
CDD
cd00818 (IleRS_core)

589L

active site
39P, 40P, 41F, 47H, 49G, 50H, 53A, 416I, 522W, 525S, 554E, 555G, 556L, 557D, 558Q, 560R, 562W, 585S, 586G, 587I, 588V, 589L, 593G, 594K, 595K, 596M, 597S, 598K, 632T
CDD
cd00818 (IleRS_core)

593G

active site
39P, 40P, 41F, 47H, 49G, 50H, 53A, 416I, 522W, 525S, 554E, 555G, 556L, 557D, 558Q, 560R, 562W, 585S, 586G, 587I, 588V, 589L, 593G, 594K, 595K, 596M, 597S, 598K, 632T
CDD
cd00818 (IleRS_core)

594K

active site
39P, 40P, 41F, 47H, 49G, 50H, 53A, 416I, 522W, 525S, 554E, 555G, 556L, 557D, 558Q, 560R, 562W, 585S, 586G, 587I, 588V, 589L, 593G, 594K, 595K, 596M, 597S, 598K, 632T
CDD
cd00818 (IleRS_core)

595K

active site
39P, 40P, 41F, 47H, 49G, 50H, 53A, 416I, 522W, 525S, 554E, 555G, 556L, 557D, 558Q, 560R, 562W, 585S, 586G, 587I, 588V, 589L, 593G, 594K, 595K, 596M, 597S, 598K, 632T
CDD
cd00818 (IleRS_core)

596M

active site
39P, 40P, 41F, 47H, 49G, 50H, 53A, 416I, 522W, 525S, 554E, 555G, 556L, 557D, 558Q, 560R, 562W, 585S, 586G, 587I, 588V, 589L, 593G, 594K, 595K, 596M, 597S, 598K, 632T
CDD
cd00818 (IleRS_core)

597S

active site
39P, 40P, 41F, 47H, 49G, 50H, 53A, 416I, 522W, 525S, 554E, 555G, 556L, 557D, 558Q, 560R, 562W, 585S, 586G, 587I, 588V, 589L, 593G, 594K, 595K, 596M, 597S, 598K, 632T
CDD
cd00818 (IleRS_core)

598K

active site
39P, 40P, 41F, 47H, 49G, 50H, 53A, 416I, 522W, 525S, 554E, 555G, 556L, 557D, 558Q, 560R, 562W, 585S, 586G, 587I, 588V, 589L, 593G, 594K, 595K, 596M, 597S, 598K, 632T
CDD
cd00818 (IleRS_core)

632T

active site
39P, 40P, 41F, 47H, 49G, 50H, 53A, 416I, 522W, 525S, 554E, 555G, 556L, 557D, 558Q, 560R, 562W, 585S, 586G, 587I, 588V, 589L, 593G, 594K, 595K, 596M, 597S, 598K, 632T
CDD
cd00818 (IleRS_core)
HIGH motif cd00818

47H

HIGH motif
47H, 48Y, 49G, 50H
CDD
cd00818 (IleRS_core)

48Y

HIGH motif
47H, 48Y, 49G, 50H
CDD
cd00818 (IleRS_core)

49G

HIGH motif
47H, 48Y, 49G, 50H
CDD
cd00818 (IleRS_core)

50H

HIGH motif
47H, 48Y, 49G, 50H
CDD
cd00818 (IleRS_core)
KMSKS motif cd00818

595K

KMSKS motif
595K, 596M, 597S, 598K, 599R
CDD
cd00818 (IleRS_core)

596M

KMSKS motif
595K, 596M, 597S, 598K, 599R
CDD
cd00818 (IleRS_core)

597S

KMSKS motif
595K, 596M, 597S, 598K, 599R
CDD
cd00818 (IleRS_core)

598K

KMSKS motif
595K, 596M, 597S, 598K, 599R
CDD
cd00818 (IleRS_core)

599R

KMSKS motif
595K, 596M, 597S, 598K, 599R
CDD
cd00818 (IleRS_core)
tRNA binding surfa...

638E

tRNA binding surface
638E, 642E, 645S, 650P, 653N, 656K, 657F, 710Y, 713V, 714P, 717L, 718K, 721E, 725N, 729R, 732R, 822E, 825R
CDD
cd07961 (Anticodon_Ia_Ile_ABEc)

642E

tRNA binding surface
638E, 642E, 645S, 650P, 653N, 656K, 657F, 710Y, 713V, 714P, 717L, 718K, 721E, 725N, 729R, 732R, 822E, 825R
CDD
cd07961 (Anticodon_Ia_Ile_ABEc)

645S

tRNA binding surface
638E, 642E, 645S, 650P, 653N, 656K, 657F, 710Y, 713V, 714P, 717L, 718K, 721E, 725N, 729R, 732R, 822E, 825R
CDD
cd07961 (Anticodon_Ia_Ile_ABEc)

650P

tRNA binding surface
638E, 642E, 645S, 650P, 653N, 656K, 657F, 710Y, 713V, 714P, 717L, 718K, 721E, 725N, 729R, 732R, 822E, 825R
CDD
cd07961 (Anticodon_Ia_Ile_ABEc)

653N

tRNA binding surface
638E, 642E, 645S, 650P, 653N, 656K, 657F, 710Y, 713V, 714P, 717L, 718K, 721E, 725N, 729R, 732R, 822E, 825R
CDD
cd07961 (Anticodon_Ia_Ile_ABEc)

656K

tRNA binding surface
638E, 642E, 645S, 650P, 653N, 656K, 657F, 710Y, 713V, 714P, 717L, 718K, 721E, 725N, 729R, 732R, 822E, 825R
CDD
cd07961 (Anticodon_Ia_Ile_ABEc)

657F

tRNA binding surface
638E, 642E, 645S, 650P, 653N, 656K, 657F, 710Y, 713V, 714P, 717L, 718K, 721E, 725N, 729R, 732R, 822E, 825R
CDD
cd07961 (Anticodon_Ia_Ile_ABEc)

710Y

tRNA binding surface
638E, 642E, 645S, 650P, 653N, 656K, 657F, 710Y, 713V, 714P, 717L, 718K, 721E, 725N, 729R, 732R, 822E, 825R
CDD
cd07961 (Anticodon_Ia_Ile_ABEc)

713V

tRNA binding surface
638E, 642E, 645S, 650P, 653N, 656K, 657F, 710Y, 713V, 714P, 717L, 718K, 721E, 725N, 729R, 732R, 822E, 825R
CDD
cd07961 (Anticodon_Ia_Ile_ABEc)

714P

tRNA binding surface
638E, 642E, 645S, 650P, 653N, 656K, 657F, 710Y, 713V, 714P, 717L, 718K, 721E, 725N, 729R, 732R, 822E, 825R
CDD
cd07961 (Anticodon_Ia_Ile_ABEc)

717L

tRNA binding surface
638E, 642E, 645S, 650P, 653N, 656K, 657F, 710Y, 713V, 714P, 717L, 718K, 721E, 725N, 729R, 732R, 822E, 825R
CDD
cd07961 (Anticodon_Ia_Ile_ABEc)

718K

tRNA binding surface
638E, 642E, 645S, 650P, 653N, 656K, 657F, 710Y, 713V, 714P, 717L, 718K, 721E, 725N, 729R, 732R, 822E, 825R
CDD
cd07961 (Anticodon_Ia_Ile_ABEc)

721E

tRNA binding surface
638E, 642E, 645S, 650P, 653N, 656K, 657F, 710Y, 713V, 714P, 717L, 718K, 721E, 725N, 729R, 732R, 822E, 825R
CDD
cd07961 (Anticodon_Ia_Ile_ABEc)

725N

tRNA binding surface
638E, 642E, 645S, 650P, 653N, 656K, 657F, 710Y, 713V, 714P, 717L, 718K, 721E, 725N, 729R, 732R, 822E, 825R
CDD
cd07961 (Anticodon_Ia_Ile_ABEc)

729R

tRNA binding surface
638E, 642E, 645S, 650P, 653N, 656K, 657F, 710Y, 713V, 714P, 717L, 718K, 721E, 725N, 729R, 732R, 822E, 825R
CDD
cd07961 (Anticodon_Ia_Ile_ABEc)

732R

tRNA binding surface
638E, 642E, 645S, 650P, 653N, 656K, 657F, 710Y, 713V, 714P, 717L, 718K, 721E, 725N, 729R, 732R, 822E, 825R
CDD
cd07961 (Anticodon_Ia_Ile_ABEc)

822E

tRNA binding surface
638E, 642E, 645S, 650P, 653N, 656K, 657F, 710Y, 713V, 714P, 717L, 718K, 721E, 725N, 729R, 732R, 822E, 825R
CDD
cd07961 (Anticodon_Ia_Ile_ABEc)

825R

tRNA binding surface
638E, 642E, 645S, 650P, 653N, 656K, 657F, 710Y, 713V, 714P, 717L, 718K, 721E, 725N, 729R, 732R, 822E, 825R
CDD
cd07961 (Anticodon_Ia_Ile_ABEc)
anticodon binding ...

653N

anticodon binding site
653N, 656K
CDD
cd07961 (Anticodon_Ia_Ile_ABEc)

656K

anticodon binding site
653N, 656K
CDD
cd07961 (Anticodon_Ia_Ile_ABEc)

Protein sequence

>MCA_00552_1
MDFPKSEEETLQFWNEIDAFQTSLKLSEGKPIYNFYDGPPFATGTPHYGHILASTVKDIIPRYAHMTGHHVERRFGWDTH
GLPVEYEIDKKLGITGKQDVMEMGIDKYNNECRAIVMRYADEWRSTIGRMGRWIDFDNDYKTLYPTFMESVWWVFKQLYE
KNSVYRGYRVMPYSTGLTTPLSNFEAQQNYKDVLDPAITVAFPLVDDPNTLLVAWTTTPWTLPSNLALCVNPDYEYAKIF
DEKTGKTYILLEKLLTTLFKNPKKEKLKVVEKIKGSELKGLKYVPLFNYFYDTFKDHGYKVITSSYVKDDSGTGIVHQAP
AFGEDDYAACLAHGVIDETRPPPNPVDDTGKFTKVVTDWEGVYVKDADRKIIKHLKEEGRILVDAQIRHSYPFCWRSDTP
LLYRTVPAWFVRVQEIIPNMLKHIDNSHWVPNAIKEGRFANWIKNARDWNISRNRYWGTPIPLWVSDDYEEIVCIGSIEE
LETLSGVKGITDLHRESIDGITIPSKKGKGNLKRIEEVFDCWFESGSMPYASQHYPFENAEKFKKGFPADFISEGLDQTR
GWFYTLLVLGTHLFDVSPFKNCIVSGIVLASDGKKMSKRLKNYPDPNLILNQYGADALRLYLINSPVLRAETLKFKEEGV
KEVISKVSLPWWNSYKFWEGQVALLKKNENIDFKYDPSLRSENVMDKWILASLQTLLTYIHKEMAEYRLYNVVPGLLKLI
EDLTNWYIRLNRSRLKGENGVKDTVNALNTLFEALYVLVRAMAPFTPFLAETIYQKLKVAIPEDFHGHDDRSVHFLEYPS
VRKELIDDKTETAVNRMRKVIELGRNIRERKTISLKIPLRTFVIIHHDPEYLADLESLKQYIIDELNIRDLILTSDEEKF
GVEYKVQADWPVLGKKLRKDIVKVKNALPSVTSDEVKVFLESKKITVGGIDLVEGDLTVIRGLGDSAVSQGQEVNTDQDV
LVIMDITIDEELQSEANAREFINRVQRYRKKLGLQATDEVQVEIDITKDPIGLDECLQKHKESIEKTLRRPLQQFGECQV
GSSLGEEDQEIGETCFKLRLIKL

GO term prediction

Biological Process

GO:0006418 tRNA aminoacylation for protein translation
GO:0006428 isoleucyl-tRNA aminoacylation

Molecular Function

GO:0000049 tRNA binding
GO:0000166 nucleotide binding
GO:0002161 aminoacyl-tRNA editing activity
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004822 isoleucine-tRNA ligase activity
GO:0005524 ATP binding

Cellular Component

GO:0005737 cytoplasm

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Entry type

Status

Per-residue features