Protein

MIA_00577_1

Length
1,179 amino acids


Browser: contig01:1656147-1659687+

Protein function

EGGNOG:0PHX5MPS1Checkpoint protein kinase
SGD closest match:S000002186MPS1Serine/threonine-protein kinase MPS1
CGD closest match:CAL0000200652MPS1Serine/threonine/tyrosine protein kinase

Protein alignments

%idAln lengthE-value
MCA_03697_175.000%3720.0MCA_03697_1
A0A0J9XKQ9_GEOCN75.815%3680.0Similar to Saccharomyces cerevisiae YDL028C MPS1 Dual-specificity kinase required for spindle pole body (SPB) duplication and spindle checkpoint function OS=Geotrichum candidum GN=BN980_GECA32s00692g PE=4 SV=1
UniRef50_A0A0J9XKQ975.815%3680.0Similar to Saccharomyces cerevisiae YDL028C MPS1 Dual-specificity kinase required for spindle pole body (SPB) duplication and spindle checkpoint function n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XKQ9_GEOCN
A0A167BZ37_9ASCO64.208%3662.82e-164Serine/threonine/tyrosine protein kinase MPS1 OS=Sugiyamaella lignohabitans GN=MPS1 PE=4 SV=1
A0A1E3PN36_9ASCO58.101%3582.05e-149Kinase-like protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_23219 PE=3 SV=1
A0A060T6M1_BLAAD57.500%3608.21e-139ARAD1B19998p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B19998g PE=4 SV=1
Q6C2I8_YARLI54.167%3607.56e-130YALI0F07557p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F07557g PE=4 SV=1
MPS1_YEAST50.000%3381.42e-115Serine/threonine-protein kinase MPS1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MPS1 PE=1 SV=2
A0A1D8PTW7_CANAL46.467%3682.25e-108Serine/threonine/tyrosine protein kinase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=MPS1 PE=4 SV=1
A0A1E4THF8_9ASCO49.653%2886.70e-92Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_57461 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1066

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 200 400 600 800 1000 1179

Detailed signature matches

    1. SSF56112 (Protein k...)
    1. PS50011 (PROTEIN_KI...)
    2. PF00069 (Pkinase)
    3. SM00220 (serkin_6)
    1. PS00107 (PROTEIN_KI...)
    1. PS00108 (PROTEIN_KI...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. cd14131 (PKc_Mps1)
  2. mobidb-lite (disord...)

Residue annotation

  1. ATP binding site c...
  2. active site cd14131
  3. polypeptide substr...
  4. secondary chemical...
  5. activation loop (A...

Protein sequence

>MIA_00577_1
MYRPHLSSLDRGNSNTEFTTATGKQAFFAHPQASAAPPMAHYQQRSLQQPFAQPTTTQFSSAGLADDPRNLFPSTSGKLG
AVSSAGPHDLDNDNDDDSVSSSDGNFKPPVLSDYAHSLFSDSRHHPPYYQQHASSSSNRHPPGALAMTDNYDTNVTRPGS
SSNTGLFNPTVASTHSNSSSNNNTNNSISNPSLRIGATNYSGTSLPSHHLLHHGNHTTSSPINGTRQQHEMKRHLNRTRH
STVHDSNMTENSTGSTSSSNSEVLPSNNHNLANINNSLQHPQGRLRHYSSSGSNNTSLSIEGVQLHSKKQDYDSPARPSA
PSRMGLDSKPQQAAAAPPTTPDADSYGNNILHQPLPPPPPPPPQLSASPVPLPTNKATARYSTTISANYTAQLFAQDATD
APHLASPPTIYQTAHMNAFTTNFSKTAVASSLYSSANGSSNNSAQPPLPPMPDGDLLSQSYGLQTPAVTKSNGRLTFNEI
RASGTVRSKRFGRGLGPPMRVSRVDNADLIPAADSKAITPSLAPGMNDDGAKQMMATSSNEAALLSSSSSGLSQSSSNSD
NFHDSYTSHLPADQNGSQDAPDNDLDDDDDDDDDDDDGNQLKPQTPLSKPSYQLDAHTEAYSTAISPHAPLPVGQTNGNE
EAAGASSHEDVILEEEDHDMYSHPKQDEPGNQDAPMNDKAQMDLEDKIERELTLERQHEELKYYLDSQQQRAASTGASPA
ASGAGSGTPIQAAPNGGPSSFNTSVSASGAPTTASSASTPIAREQTSSDHQSITPQPQRVSQDQPLQQKQHPLQQHHLQS
QPHQLHQSKAIPSKKPKNIVYVNGQAYQRLELIGKGGSSKVYKAQSVNGRVYAIKRVSCDEDIDDMVLKGFKGEIDLLKR
LKDEERVVKLIDFEMRATSIYVVMECGEIDLAHVLNARLSLPLDISFVRYYANEMFRCVAAVHKHGIVHSDLKPANFLLV
KGMLKIIDFGIANVVPDYTVNVHRDAQIGTPNYMAPEALLDASHVYANPSTPASVPSGGPGSSIESYRSMNPATQRPKTT
TKFKVGRPSDVWSCGCIIYQMIYGRPPYSDYKGTQRMLAIINPEVQIAYPRQGSGSVRVPKEAIEAMRGCLDRDPTQRLT
IEAAVNGGFLNPQAVDRRFIHDLLGHAVKYGAERGNSITAKEVEMLTENVWKKIQASNM

GO term prediction

Biological Process

GO:0006468 protein phosphorylation

Molecular Function

GO:0004672 protein kinase activity
GO:0005524 ATP binding

Cellular Component

None predicted.