Protein
MIA_00569_1
Length
275 amino acids
Browser: contig01:1643082-1643994-
Protein function
| EGGNOG: | 0PPMY | BNA7 | Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites (By similarity) |
|---|---|---|---|
| SGD closest match: | S000002836 | BNA7 | Kynurenine formamidase |
| CGD closest match: | CAL0000192193 | BNA7 | Kynurenine formamidase |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MCA_04924_1 | 43.023% | 258 | 1.03e-62 | MCA_04924_1 |
| A0A0J9X4U1_GEOCN | 36.156% | 307 | 2.54e-47 | Similar to Saccharomyces cerevisiae YDR428C BNA7 Formylkynurenine formamidase, involved in the de novo biosynthesis of NAD from tryptophan via kynurenine OS=Geotrichum candidum GN=BN980_GECA02s06456g PE=4 SV=1 |
| UniRef50_A0A0J9X4U1 | 36.156% | 307 | 5.20e-44 | Similar to Saccharomyces cerevisiae YDR428C BNA7 Formylkynurenine formamidase, involved in the de novo biosynthesis of NAD from tryptophan via kynurenine n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X4U1_GEOCN |
| A0A167D7X6_9ASCO | 33.835% | 266 | 2.09e-35 | Kynurenine formamidase OS=Sugiyamaella lignohabitans GN=BNA7 PE=3 SV=1 |
| A0A060TDW1_BLAAD | 32.432% | 259 | 2.40e-35 | ARAD1D03190p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D03190g PE=4 SV=1 |
| A0A1E3PE60_9ASCO | 32.584% | 267 | 5.51e-34 | Kynurenine formamidase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=BNA7 PE=3 SV=1 |
| A0A1E4TGT7_9ASCO | 33.906% | 233 | 4.82e-25 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_26848 PE=4 SV=1 |
| Q6CCT4_YARLI | 26.829% | 205 | 1.56e-16 | YALI0C06732p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C06732g PE=4 SV=1 |
| KFA_YEAST | 26.891% | 238 | 2.26e-13 | Kynurenine formamidase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=BNA7 PE=1 SV=1 |
| KFA_CANAL | 27.111% | 225 | 1.26e-12 | Kynurenine formamidase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=BNA7 PE=3 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0202
Protein family membership
None predicted.
Domains and repeats
-
Domain
1
50
100
150
200
250
275
Detailed signature matches
-
-
SSF53474 (alpha/bet...)
-
-
Protein sequence
>MIA_00569_1 MPVDYTAVSYSGTLDAPTDPLRRIGLYKHSSASEYPQFWFIFIHGGAWRDPRIDHTDGLPLISALLKKYPKSLACASIDY TLAKPLDGSNGRGAQHPDFTLDTLAALTYLRTHHRVEKFALSGHSAGAFMSLQVFIEPKLEETNVFAREKCAAVFGISGI YSLPLLPIEDASYTGFTEEAFGVDQTLWEVPSVVPYIKGHVAPFPKTTTFKLVIIYSKSDELLNPKFQPVKGPEIYRPIL GDNNVIVEETVGLHDESYKVQRTADIVEKYLTEYL
GO term prediction
Biological Process
None predicted.
Molecular Function
None predicted.
Cellular Component
None predicted.