Protein
MCA_04924_1
Length
263 amino acids
Gene name: BNA7A
Description: Kynurenine formamidase
Browser: contigC:4442797-4443589+
RNA-seq: read pairs 374, FPKM 17.5, percentile rank 37.8% (100% = highest expression)
Protein function
| Annotation: | BNA7A | Kynurenine formamidase | |
|---|---|---|---|
| EGGNOG: | 0PPMY | BNA7 | Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites (By similarity) |
| SGD closest match: | S000002836 | BNA7 | Kynurenine formamidase |
| CGD closest match: | CAL0000192193 | BNA7 | Kynurenine formamidase |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_00569_1 | 43.02% | 258 | 2e-61 | MIA_00569_1 |
| A0A1E3PE60_9ASCO | 37.64% | 271 | 9e-51 | Kynurenine formamidase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=BNA7 PE=3 SV=1 |
| UniRef50_A0A1E3PE60 | 37.64% | 271 | 3e-47 | Kynurenine formamidase n=1 Tax=Nadsonia fulvescens var. elongata DSM 6958 TaxID=857566 RepID=A0A1E3PE60_9ASCO |
| A0A167D7X6_9ASCO | 35.69% | 269 | 2e-48 | Kynurenine formamidase OS=Sugiyamaella lignohabitans GN=BNA7 PE=3 SV=1 |
| A0A0J9X4U1_GEOCN | 36.11% | 288 | 2e-44 | Similar to Saccharomyces cerevisiae YDR428C BNA7 Formylkynurenine formamidase, involved in the de novo biosynthesis of NAD from tryptophan via kynurenine OS=Geotrichum candidum GN=BN980_GECA02s06456g PE=4 SV=1 |
| A0A060TDW1_BLAAD | 32.16% | 255 | 3e-38 | ARAD1D03190p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D03190g PE=4 SV=1 |
| A0A1E4TGT7_9ASCO | 37.26% | 263 | 2e-36 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_26848 PE=4 SV=1 |
| Q6C748_YARLI | 31.73% | 208 | 7e-21 | Kynurenine formamidase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=BNA7 PE=3 SV=1 |
| KFA_CANAL | 32.47% | 231 | 3e-20 | Kynurenine formamidase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=BNA7 PE=3 SV=1 |
| KFA_YEAST | 29.80% | 198 | 2e-10 | Kynurenine formamidase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=BNA7 PE=1 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0689
Protein family membership
None predicted.
Domains and repeats
-
Domain
1
50
100
150
200
263
Detailed signature matches
-
-
SSF53474 (alpha/bet...)
-
-
Protein sequence
>MCA_04924_1 MDALDVEIHSYGNQDLQKVAVYKHNSNTLSNLPKRWLIFIHGGAWRDPNNTYEDGNFLISSLLNSFPNVLSAASIKYRLT SNKPVSAIYPDFVEDLILSLDFLDKNYPIDEFILVGHSAGAFNALACLTPENNLLKAYSNVLSKCKSVIGIAGIYSLPLL LDEDKSYNGFIEEAFGMNHSAWPLLAEKLASSPLHKDVKLLIVYSKEDELLNYKYQPKYALETFPSILGQQNVTSGITEG QHEDTYKSPKTVEIITKFLNQLG
GO term prediction
Biological Process
None predicted.
Molecular Function
None predicted.
Cellular Component
None predicted.