Protein
MIA_00498_1
Length
1,035 amino acids
Browser: contig01:1435958-1439066-
Protein function
EGGNOG: | 0PFCT | HRD3 | ubiquitin-protein ligase Sel1 Ubx2 |
---|---|---|---|
SGD closest match: | S000004197 | HRD3 | ERAD-associated E3 ubiquitin-protein ligase component HRD3 |
CGD closest match: | CAL0000187118 | orf19.1191 | Ubiquitin ligase complex subunit |
Protein alignments
%id | Aln length | E-value | ||
---|---|---|---|---|
MCA_00147_1 | 51.250% | 880 | 0.0 | MCA_00147_1 |
A0A0J9XCR8_GEOCN | 41.774% | 620 | 1.86e-140 | Similar to Saccharomyces cerevisiae YLR207W HRD3 Resident protein of the ER membrane that plays a central role in ER-associated protein degradation (ERAD) OS=Geotrichum candidum GN=BN980_GECA09s03508g PE=4 SV=1 |
UniRef50_A0A0J9XCR8 | 41.774% | 620 | 3.81e-137 | Similar to Saccharomyces cerevisiae YLR207W HRD3 Resident protein of the ER membrane that plays a central role in ER-associated protein degradation (ERAD) n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XCR8_GEOCN |
A0A167D442_9ASCO | 37.080% | 685 | 6.81e-113 | Ubiquitin ligase complex subunit HRD3 OS=Sugiyamaella lignohabitans GN=HRD3 PE=4 SV=1 |
A0A060TAF7_BLAAD | 30.857% | 700 | 5.52e-78 | ARAD1B06666p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B06666g PE=4 SV=1 |
Q6C383_YARLI | 31.947% | 601 | 4.79e-77 | YALI0F01859p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F01859g PE=4 SV=1 |
A0A1E4TL36_9ASCO | 30.619% | 614 | 9.98e-70 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_86889 PE=4 SV=1 |
A0A1E3PCW6_9ASCO | 28.947% | 646 | 4.67e-59 | HCP-like protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_48282 PE=4 SV=1 |
A0A1D8PPB6_CANAL | 28.453% | 601 | 6.30e-50 | Ubiquitin ligase complex subunit OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.1191 PE=4 SV=1 |
HRD3_YEAST | 26.260% | 377 | 1.14e-19 | ERAD-associated E3 ubiquitin-protein ligase component HRD3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=HRD3 PE=1 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0203
Protein family membership
None predicted.
Domains and repeats
-
Repeat
1
100
200
300
400
500
600
700
800
900
1035
Detailed signature matches
no IPR
Unintegrated signatures
-
CYTOPLASMIC_D... (C...)
-
-
-
NON_CYTOPLASM... (N...)
-
SSF81901 (HCP-like)
-
-
TRANSMEMBRANE (Tran...)
-
mobidb-lite (disord...)
Protein sequence
>MIA_00498_1 MLTIQQINNFRIYFIVLVAGLFCSVAYLSYLQTTEPENPVALRTPSQQTEDSQITFQSPPSQKHISEYATGDPEIDRSRG RILYMEARSILNALPDVTNPDNIGRYYRPRCSIWSLLLDSGVQSICNTLLFPIPESSRTRLCAKLSFENSVPTNPPEVLS TPSKTTSAPPPIFKNTKTSLSPERLEKLKKLESKKLELKRAFELLTDASSLGDIDATYTRAELYFYGNYTHPQDFYKSLR FYKQVAQKTGNSSAQFMIGIMYSTGMFGSTPQDQARANLYYTFAAKNGDYRAKMAMAYRHYHGIATPKNAKLAAEIYKET ATIAYEYAINGPPGGRHLPQYGWLLSDKDGGIFGEGASRVAPVRHYPLLPSSSTQSFDMAVRYLNYLSLLDDTAAPAYYA LARLYYDGDIIIDPDYKTAGEYASECIREAQASDSHKSTEGACLGFLGFRYLRGEGTDKNYDFAKQLFEIGIRADDELSA TGLGLMYWKGIGVERDEKKAIDLFKKADNNGAAHLYLGEIFLGQGDINAAYMQFDKAVKRSNTFAIYHIGMLLSNGARKK DSKTPYFQIVSDPVPYFQIVSERIHEFHSPLRWAHKQYSEGDFGSALLGFLIAAEEGYNEAQINLAYMLDDQRNVLDIHR ILSFFSFKQNNDGFTTQPLNPLHNKAIQGEHCDIGQFIYRDPSDYATWTRERDLTSFTYWSRLANDYNVDAIVKVGDYFL NGIGVKSNPSKAASQYQVAAEYFSAIARWNLGWMYENGIGVEQDFHLAKRYYDNAALVSRDAYFPVTLSLFKLRARSYWN SWRRNPADHRHNTFNEPISNDEKNILDKVEGGSSEQGEKPKSFVEAIKLFWKKWNERGGFNPELEDDEDDEEEVLETFVD AVDAVEFIDKYLIFILIFVILSYMFRHWQNRGGNIQGIRERIRQFQGARNRLGLGQNPNPNPNPNPNPNPNPNPNPNLNP NPNPNPHENLNENPNENPNENPNENPNENPNENPNENPNENPNEDQNENQNPNQNENGNHLDAPGPIPIENLGHH
GO term prediction
Biological Process
None predicted.
Molecular Function
None predicted.
Cellular Component
None predicted.