Protein

MIA_00498_1

Length
1,035 amino acids


Browser: contig01:1435958-1439066-

Protein function

EGGNOG:0PFCTHRD3ubiquitin-protein ligase Sel1 Ubx2
SGD closest match:S000004197HRD3ERAD-associated E3 ubiquitin-protein ligase component HRD3
CGD closest match:CAL0000187118orf19.1191Ubiquitin ligase complex subunit

Protein alignments

%idAln lengthE-value
MCA_00147_151.250%8800.0MCA_00147_1
A0A0J9XCR8_GEOCN41.774%6201.86e-140Similar to Saccharomyces cerevisiae YLR207W HRD3 Resident protein of the ER membrane that plays a central role in ER-associated protein degradation (ERAD) OS=Geotrichum candidum GN=BN980_GECA09s03508g PE=4 SV=1
UniRef50_A0A0J9XCR841.774%6203.81e-137Similar to Saccharomyces cerevisiae YLR207W HRD3 Resident protein of the ER membrane that plays a central role in ER-associated protein degradation (ERAD) n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XCR8_GEOCN
A0A167D442_9ASCO37.080%6856.81e-113Ubiquitin ligase complex subunit HRD3 OS=Sugiyamaella lignohabitans GN=HRD3 PE=4 SV=1
A0A060TAF7_BLAAD30.857%7005.52e-78ARAD1B06666p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B06666g PE=4 SV=1
Q6C383_YARLI31.947%6014.79e-77YALI0F01859p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F01859g PE=4 SV=1
A0A1E4TL36_9ASCO30.619%6149.98e-70Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_86889 PE=4 SV=1
A0A1E3PCW6_9ASCO28.947%6464.67e-59HCP-like protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_48282 PE=4 SV=1
A0A1D8PPB6_CANAL28.453%6016.30e-50Ubiquitin ligase complex subunit OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.1191 PE=4 SV=1
HRD3_YEAST26.260%3771.14e-19ERAD-associated E3 ubiquitin-protein ligase component HRD3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=HRD3 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0203

Protein family membership

None predicted.

Domains and repeats

  1. Repeat
1 100 200 300 400 500 600 700 800 900 1035

Detailed signature matches

    1. SM00671 (sel1)
    2. PF08238 (Sel1)
Unintegrated signatures no IPR
Unintegrated signatures
  1. SSF81901 (HCP-like)
  2. TRANSMEMBRANE (Tran...)
  3. mobidb-lite (disord...)

Protein sequence

>MIA_00498_1
MLTIQQINNFRIYFIVLVAGLFCSVAYLSYLQTTEPENPVALRTPSQQTEDSQITFQSPPSQKHISEYATGDPEIDRSRG
RILYMEARSILNALPDVTNPDNIGRYYRPRCSIWSLLLDSGVQSICNTLLFPIPESSRTRLCAKLSFENSVPTNPPEVLS
TPSKTTSAPPPIFKNTKTSLSPERLEKLKKLESKKLELKRAFELLTDASSLGDIDATYTRAELYFYGNYTHPQDFYKSLR
FYKQVAQKTGNSSAQFMIGIMYSTGMFGSTPQDQARANLYYTFAAKNGDYRAKMAMAYRHYHGIATPKNAKLAAEIYKET
ATIAYEYAINGPPGGRHLPQYGWLLSDKDGGIFGEGASRVAPVRHYPLLPSSSTQSFDMAVRYLNYLSLLDDTAAPAYYA
LARLYYDGDIIIDPDYKTAGEYASECIREAQASDSHKSTEGACLGFLGFRYLRGEGTDKNYDFAKQLFEIGIRADDELSA
TGLGLMYWKGIGVERDEKKAIDLFKKADNNGAAHLYLGEIFLGQGDINAAYMQFDKAVKRSNTFAIYHIGMLLSNGARKK
DSKTPYFQIVSDPVPYFQIVSERIHEFHSPLRWAHKQYSEGDFGSALLGFLIAAEEGYNEAQINLAYMLDDQRNVLDIHR
ILSFFSFKQNNDGFTTQPLNPLHNKAIQGEHCDIGQFIYRDPSDYATWTRERDLTSFTYWSRLANDYNVDAIVKVGDYFL
NGIGVKSNPSKAASQYQVAAEYFSAIARWNLGWMYENGIGVEQDFHLAKRYYDNAALVSRDAYFPVTLSLFKLRARSYWN
SWRRNPADHRHNTFNEPISNDEKNILDKVEGGSSEQGEKPKSFVEAIKLFWKKWNERGGFNPELEDDEDDEEEVLETFVD
AVDAVEFIDKYLIFILIFVILSYMFRHWQNRGGNIQGIRERIRQFQGARNRLGLGQNPNPNPNPNPNPNPNPNPNPNLNP
NPNPNPHENLNENPNENPNENPNENPNENPNENPNENPNENPNEDQNENQNPNQNENGNHLDAPGPIPIENLGHH

GO term prediction

Biological Process

None predicted.

Molecular Function

None predicted.

Cellular Component

None predicted.