MIA_00494_1

Protein

Length

1,169 amino acids

Protein function

EGGNOG:	0PG3S	RET1	DNA-directed RNA Polymerase
SGD closest match:	S000005733	RET1	DNA-directed RNA polymerase III subunit RPC2
CGD closest match:	CAL0000190208	CAALFM_CR05550CA	DNA-directed RNA polymerase subunit beta

Protein alignments

	%id	Aln length
MCA_00143_1	91.630%	1147	MCA_00143_1
A0A0J9XFV7_GEOCN	84.756%	1148	DNA-directed RNA polymerase subunit beta OS=Geotrichum candidum GN=BN980_GECA14s01264g PE=3 SV=1
A0A060T6K8_BLAAD	78.578%	1153	DNA-directed RNA polymerase subunit beta OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B19536g PE=3 SV=1
A0A1E3PCK7_9ASCO	77.971%	1153	DNA-directed RNA polymerase subunit beta OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_53794 PE=3 SV=1
A0A167DJD8_9ASCO	77.875%	1148	DNA-directed RNA polymerase subunit beta OS=Sugiyamaella lignohabitans GN=RET1 PE=3 SV=1
Q6CEE6_YARLI	75.799%	1157	DNA-directed RNA polymerase subunit beta OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B16258g PE=3 SV=1
Q59M52_CANAL	75.910%	1154	DNA-directed RNA polymerase subunit beta OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CAALFM_CR05550CA PE=3 SV=1
RPC2_YEAST	75.328%	1143	DNA-directed RNA polymerase III subunit RPC2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RET1 PE=1 SV=2
UniRef50_P22276	75.328%	1143	DNA-directed RNA polymerase III subunit RPC2 n=385 Tax=Eukaryota TaxID=2759 RepID=RPC2_YEAST
A0A1E4TJ86_9ASCO	70.725%	1158	DNA-directed RNA polymerase subunit beta OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_76153 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0037

Protein family membership

DNA-directed RNA polymerase, subunit 2 (IPR015712)

Domains and repeats

Domain
66 - 427
RNA polymerase, beta subunit, protrusion (IPR007644)
472 - 535
RNA polymerase Rpb2, domain 3 (IPR007645)
572 - 633
RNA polymerase Rpb2, domain 4 (IPR007646)
701 - 1,078
DNA-directed RNA polymerase, subunit 2, domain 6 (IPR007120)
1,080 - 1,164
RNA polymerase Rpb2, domain 7 (IPR007641)
Domain
214 - 393
RNA polymerase Rpb2, domain 2 (IPR007642)
654 - 694
RNA polymerase Rpb2, domain 5 (IPR007647)

1 200 400 600 800 1000 1169

Detailed signature matches

IPR015712

DNA-directed RNA polymerase, subunit 2
1. cd00653 (RNA_pol_B_...)
  
  67 - 1,164
  
  CDD
  cd00653 (RNA_pol_B_RPB2)
IPR007644

RNA polymerase, beta subunit, protrusion
1. PF04563 (RNA_pol_Rp...)
  
  66 - 427
  
  Pfam
  PF04563 (RNA_pol_Rpb2_1)
IPR007642

RNA polymerase Rpb2, domain 2
1. PF04561 (RNA_pol_Rp...)
  
  214 - 393
  
  Pfam
  PF04561 (RNA_pol_Rpb2_2)
IPR007645

RNA polymerase Rpb2, domain 3
1. PF04565 (RNA_pol_Rp...)
  
  472 - 535
  
  Pfam
  PF04565 (RNA_pol_Rpb2_3)
IPR007646

RNA polymerase Rpb2, domain 4
1. PF04566 (RNA_pol_Rp...)
  
  572 - 633
  
  Pfam
  PF04566 (RNA_pol_Rpb2_4)
IPR007647

RNA polymerase Rpb2, domain 5
1. PF04567 (RNA_pol_Rp...)
  
  654 - 694
  
  Pfam
  PF04567 (RNA_pol_Rpb2_5)
IPR007120

DNA-directed RNA polymerase, subunit 2, domain 6
1. G3DSA:2.40.27...
  
  859 - 1,064
  
  GENE3D
  G3DSA:2.40.270.10 (G3DSA:2.40.270.10)
2. PF00562 (RNA_pol_Rp...)
  
  701 - 1,078
  
  Pfam
  PF00562 (RNA_pol_Rpb2_6)
IPR007641

RNA polymerase Rpb2, domain 7
1. PF04560 (RNA_pol_Rp...)
  
  1,080 - 1,164
  
  Pfam
  PF04560 (RNA_pol_Rpb2_7)
IPR007121

RNA polymerase, beta subunit, conserved site
1. PS01166 (RNA_POL_BETA)
  
  931 - 943
  
  PROSITE patterns
  PS01166 (RNA_POL_BETA)

no IPR

Unintegrated signatures

G3DSA:3.90.11...

58 - 740

GENE3D
G3DSA:3.90.1100.10 (G3DSA:3.90.1100.10)
G3DSA:3.90.18...

1,081 - 1,158

GENE3D
G3DSA:3.90.1800.10 (G3DSA:3.90.1800.10)
SSF64484 (beta and ...)

47 - 1,166

SUPERFAMILY
SSF64484 (beta and beta-prime subunits of DNA dependent RNA-polymerase)
mobidb-lite (disord...)

1 - 24

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

RPB12 interaction ...

133R

RPB12 interaction site
133R, 801R, 846D, 848D, 852Q, 853V, 854G, 856K
CDD
cd00653 (RNA_pol_B_RPB2)

801R

RPB12 interaction site
133R, 801R, 846D, 848D, 852Q, 853V, 854G, 856K
CDD
cd00653 (RNA_pol_B_RPB2)

846D

RPB12 interaction site
133R, 801R, 846D, 848D, 852Q, 853V, 854G, 856K
CDD
cd00653 (RNA_pol_B_RPB2)

848D

RPB12 interaction site
133R, 801R, 846D, 848D, 852Q, 853V, 854G, 856K
CDD
cd00653 (RNA_pol_B_RPB2)

852Q

RPB12 interaction site
133R, 801R, 846D, 848D, 852Q, 853V, 854G, 856K
CDD
cd00653 (RNA_pol_B_RPB2)

853V

RPB12 interaction site
133R, 801R, 846D, 848D, 852Q, 853V, 854G, 856K
CDD
cd00653 (RNA_pol_B_RPB2)

854G

RPB12 interaction site
133R, 801R, 846D, 848D, 852Q, 853V, 854G, 856K
CDD
cd00653 (RNA_pol_B_RPB2)

856K

RPB12 interaction site
133R, 801R, 846D, 848D, 852Q, 853V, 854G, 856K
CDD
cd00653 (RNA_pol_B_RPB2)
RPB1 interaction s...

500G

RPB1 interaction site
500G, 502R, 503A, 504L, 506P, 509F, 514T, 691E, 709H, 710H, 711N, 713S, 776V, 777M, 778S, 779Y, 782Y, 784I, 785E, 786D, 941K, 943V, 945G, 967N, 969H, 972P, 975M, 980M, 984V, 1,001F, 1,028S, 1,036Q, 1,037A, 1,038Y, 1,040F, 1,053V, 1,056K, 1,057M, 1,058H, 1,060R, 1,061A, 1,082L, 1,083R, 1,084L, 1,088E, 1,090D, 1,091C, 1,093I, 1,095Y, 1,096G, 1,097A, 1,098S, 1,099Q, 1,100L, 1,102L, 1,103E, 1,104R, 1,105L, 1,106M, 1,107L, 1,111A, 1,144P, 1,148K, 1,150L, 1,152Q, 1,153E, 1,155I, 1,157M, 1,158N, 1,159I, 1,160A, 1,162R, 1,164K
CDD
cd00653 (RNA_pol_B_RPB2)

502R

RPB1 interaction site
500G, 502R, 503A, 504L, 506P, 509F, 514T, 691E, 709H, 710H, 711N, 713S, 776V, 777M, 778S, 779Y, 782Y, 784I, 785E, 786D, 941K, 943V, 945G, 967N, 969H, 972P, 975M, 980M, 984V, 1,001F, 1,028S, 1,036Q, 1,037A, 1,038Y, 1,040F, 1,053V, 1,056K, 1,057M, 1,058H, 1,060R, 1,061A, 1,082L, 1,083R, 1,084L, 1,088E, 1,090D, 1,091C, 1,093I, 1,095Y, 1,096G, 1,097A, 1,098S, 1,099Q, 1,100L, 1,102L, 1,103E, 1,104R, 1,105L, 1,106M, 1,107L, 1,111A, 1,144P, 1,148K, 1,150L, 1,152Q, 1,153E, 1,155I, 1,157M, 1,158N, 1,159I, 1,160A, 1,162R, 1,164K
CDD
cd00653 (RNA_pol_B_RPB2)

503A

RPB1 interaction site
500G, 502R, 503A, 504L, 506P, 509F, 514T, 691E, 709H, 710H, 711N, 713S, 776V, 777M, 778S, 779Y, 782Y, 784I, 785E, 786D, 941K, 943V, 945G, 967N, 969H, 972P, 975M, 980M, 984V, 1,001F, 1,028S, 1,036Q, 1,037A, 1,038Y, 1,040F, 1,053V, 1,056K, 1,057M, 1,058H, 1,060R, 1,061A, 1,082L, 1,083R, 1,084L, 1,088E, 1,090D, 1,091C, 1,093I, 1,095Y, 1,096G, 1,097A, 1,098S, 1,099Q, 1,100L, 1,102L, 1,103E, 1,104R, 1,105L, 1,106M, 1,107L, 1,111A, 1,144P, 1,148K, 1,150L, 1,152Q, 1,153E, 1,155I, 1,157M, 1,158N, 1,159I, 1,160A, 1,162R, 1,164K
CDD
cd00653 (RNA_pol_B_RPB2)

504L

RPB1 interaction site
500G, 502R, 503A, 504L, 506P, 509F, 514T, 691E, 709H, 710H, 711N, 713S, 776V, 777M, 778S, 779Y, 782Y, 784I, 785E, 786D, 941K, 943V, 945G, 967N, 969H, 972P, 975M, 980M, 984V, 1,001F, 1,028S, 1,036Q, 1,037A, 1,038Y, 1,040F, 1,053V, 1,056K, 1,057M, 1,058H, 1,060R, 1,061A, 1,082L, 1,083R, 1,084L, 1,088E, 1,090D, 1,091C, 1,093I, 1,095Y, 1,096G, 1,097A, 1,098S, 1,099Q, 1,100L, 1,102L, 1,103E, 1,104R, 1,105L, 1,106M, 1,107L, 1,111A, 1,144P, 1,148K, 1,150L, 1,152Q, 1,153E, 1,155I, 1,157M, 1,158N, 1,159I, 1,160A, 1,162R, 1,164K
CDD
cd00653 (RNA_pol_B_RPB2)

506P

RPB1 interaction site
500G, 502R, 503A, 504L, 506P, 509F, 514T, 691E, 709H, 710H, 711N, 713S, 776V, 777M, 778S, 779Y, 782Y, 784I, 785E, 786D, 941K, 943V, 945G, 967N, 969H, 972P, 975M, 980M, 984V, 1,001F, 1,028S, 1,036Q, 1,037A, 1,038Y, 1,040F, 1,053V, 1,056K, 1,057M, 1,058H, 1,060R, 1,061A, 1,082L, 1,083R, 1,084L, 1,088E, 1,090D, 1,091C, 1,093I, 1,095Y, 1,096G, 1,097A, 1,098S, 1,099Q, 1,100L, 1,102L, 1,103E, 1,104R, 1,105L, 1,106M, 1,107L, 1,111A, 1,144P, 1,148K, 1,150L, 1,152Q, 1,153E, 1,155I, 1,157M, 1,158N, 1,159I, 1,160A, 1,162R, 1,164K
CDD
cd00653 (RNA_pol_B_RPB2)

509F

RPB1 interaction site
500G, 502R, 503A, 504L, 506P, 509F, 514T, 691E, 709H, 710H, 711N, 713S, 776V, 777M, 778S, 779Y, 782Y, 784I, 785E, 786D, 941K, 943V, 945G, 967N, 969H, 972P, 975M, 980M, 984V, 1,001F, 1,028S, 1,036Q, 1,037A, 1,038Y, 1,040F, 1,053V, 1,056K, 1,057M, 1,058H, 1,060R, 1,061A, 1,082L, 1,083R, 1,084L, 1,088E, 1,090D, 1,091C, 1,093I, 1,095Y, 1,096G, 1,097A, 1,098S, 1,099Q, 1,100L, 1,102L, 1,103E, 1,104R, 1,105L, 1,106M, 1,107L, 1,111A, 1,144P, 1,148K, 1,150L, 1,152Q, 1,153E, 1,155I, 1,157M, 1,158N, 1,159I, 1,160A, 1,162R, 1,164K
CDD
cd00653 (RNA_pol_B_RPB2)

514T

RPB1 interaction site
500G, 502R, 503A, 504L, 506P, 509F, 514T, 691E, 709H, 710H, 711N, 713S, 776V, 777M, 778S, 779Y, 782Y, 784I, 785E, 786D, 941K, 943V, 945G, 967N, 969H, 972P, 975M, 980M, 984V, 1,001F, 1,028S, 1,036Q, 1,037A, 1,038Y, 1,040F, 1,053V, 1,056K, 1,057M, 1,058H, 1,060R, 1,061A, 1,082L, 1,083R, 1,084L, 1,088E, 1,090D, 1,091C, 1,093I, 1,095Y, 1,096G, 1,097A, 1,098S, 1,099Q, 1,100L, 1,102L, 1,103E, 1,104R, 1,105L, 1,106M, 1,107L, 1,111A, 1,144P, 1,148K, 1,150L, 1,152Q, 1,153E, 1,155I, 1,157M, 1,158N, 1,159I, 1,160A, 1,162R, 1,164K
CDD
cd00653 (RNA_pol_B_RPB2)

691E

RPB1 interaction site
500G, 502R, 503A, 504L, 506P, 509F, 514T, 691E, 709H, 710H, 711N, 713S, 776V, 777M, 778S, 779Y, 782Y, 784I, 785E, 786D, 941K, 943V, 945G, 967N, 969H, 972P, 975M, 980M, 984V, 1,001F, 1,028S, 1,036Q, 1,037A, 1,038Y, 1,040F, 1,053V, 1,056K, 1,057M, 1,058H, 1,060R, 1,061A, 1,082L, 1,083R, 1,084L, 1,088E, 1,090D, 1,091C, 1,093I, 1,095Y, 1,096G, 1,097A, 1,098S, 1,099Q, 1,100L, 1,102L, 1,103E, 1,104R, 1,105L, 1,106M, 1,107L, 1,111A, 1,144P, 1,148K, 1,150L, 1,152Q, 1,153E, 1,155I, 1,157M, 1,158N, 1,159I, 1,160A, 1,162R, 1,164K
CDD
cd00653 (RNA_pol_B_RPB2)

709H

RPB1 interaction site
500G, 502R, 503A, 504L, 506P, 509F, 514T, 691E, 709H, 710H, 711N, 713S, 776V, 777M, 778S, 779Y, 782Y, 784I, 785E, 786D, 941K, 943V, 945G, 967N, 969H, 972P, 975M, 980M, 984V, 1,001F, 1,028S, 1,036Q, 1,037A, 1,038Y, 1,040F, 1,053V, 1,056K, 1,057M, 1,058H, 1,060R, 1,061A, 1,082L, 1,083R, 1,084L, 1,088E, 1,090D, 1,091C, 1,093I, 1,095Y, 1,096G, 1,097A, 1,098S, 1,099Q, 1,100L, 1,102L, 1,103E, 1,104R, 1,105L, 1,106M, 1,107L, 1,111A, 1,144P, 1,148K, 1,150L, 1,152Q, 1,153E, 1,155I, 1,157M, 1,158N, 1,159I, 1,160A, 1,162R, 1,164K
CDD
cd00653 (RNA_pol_B_RPB2)

710H

RPB1 interaction site
500G, 502R, 503A, 504L, 506P, 509F, 514T, 691E, 709H, 710H, 711N, 713S, 776V, 777M, 778S, 779Y, 782Y, 784I, 785E, 786D, 941K, 943V, 945G, 967N, 969H, 972P, 975M, 980M, 984V, 1,001F, 1,028S, 1,036Q, 1,037A, 1,038Y, 1,040F, 1,053V, 1,056K, 1,057M, 1,058H, 1,060R, 1,061A, 1,082L, 1,083R, 1,084L, 1,088E, 1,090D, 1,091C, 1,093I, 1,095Y, 1,096G, 1,097A, 1,098S, 1,099Q, 1,100L, 1,102L, 1,103E, 1,104R, 1,105L, 1,106M, 1,107L, 1,111A, 1,144P, 1,148K, 1,150L, 1,152Q, 1,153E, 1,155I, 1,157M, 1,158N, 1,159I, 1,160A, 1,162R, 1,164K
CDD
cd00653 (RNA_pol_B_RPB2)

711N

RPB1 interaction site
500G, 502R, 503A, 504L, 506P, 509F, 514T, 691E, 709H, 710H, 711N, 713S, 776V, 777M, 778S, 779Y, 782Y, 784I, 785E, 786D, 941K, 943V, 945G, 967N, 969H, 972P, 975M, 980M, 984V, 1,001F, 1,028S, 1,036Q, 1,037A, 1,038Y, 1,040F, 1,053V, 1,056K, 1,057M, 1,058H, 1,060R, 1,061A, 1,082L, 1,083R, 1,084L, 1,088E, 1,090D, 1,091C, 1,093I, 1,095Y, 1,096G, 1,097A, 1,098S, 1,099Q, 1,100L, 1,102L, 1,103E, 1,104R, 1,105L, 1,106M, 1,107L, 1,111A, 1,144P, 1,148K, 1,150L, 1,152Q, 1,153E, 1,155I, 1,157M, 1,158N, 1,159I, 1,160A, 1,162R, 1,164K
CDD
cd00653 (RNA_pol_B_RPB2)

713S

RPB1 interaction site
500G, 502R, 503A, 504L, 506P, 509F, 514T, 691E, 709H, 710H, 711N, 713S, 776V, 777M, 778S, 779Y, 782Y, 784I, 785E, 786D, 941K, 943V, 945G, 967N, 969H, 972P, 975M, 980M, 984V, 1,001F, 1,028S, 1,036Q, 1,037A, 1,038Y, 1,040F, 1,053V, 1,056K, 1,057M, 1,058H, 1,060R, 1,061A, 1,082L, 1,083R, 1,084L, 1,088E, 1,090D, 1,091C, 1,093I, 1,095Y, 1,096G, 1,097A, 1,098S, 1,099Q, 1,100L, 1,102L, 1,103E, 1,104R, 1,105L, 1,106M, 1,107L, 1,111A, 1,144P, 1,148K, 1,150L, 1,152Q, 1,153E, 1,155I, 1,157M, 1,158N, 1,159I, 1,160A, 1,162R, 1,164K
CDD
cd00653 (RNA_pol_B_RPB2)

776V

RPB1 interaction site
500G, 502R, 503A, 504L, 506P, 509F, 514T, 691E, 709H, 710H, 711N, 713S, 776V, 777M, 778S, 779Y, 782Y, 784I, 785E, 786D, 941K, 943V, 945G, 967N, 969H, 972P, 975M, 980M, 984V, 1,001F, 1,028S, 1,036Q, 1,037A, 1,038Y, 1,040F, 1,053V, 1,056K, 1,057M, 1,058H, 1,060R, 1,061A, 1,082L, 1,083R, 1,084L, 1,088E, 1,090D, 1,091C, 1,093I, 1,095Y, 1,096G, 1,097A, 1,098S, 1,099Q, 1,100L, 1,102L, 1,103E, 1,104R, 1,105L, 1,106M, 1,107L, 1,111A, 1,144P, 1,148K, 1,150L, 1,152Q, 1,153E, 1,155I, 1,157M, 1,158N, 1,159I, 1,160A, 1,162R, 1,164K
CDD
cd00653 (RNA_pol_B_RPB2)

777M

RPB1 interaction site
500G, 502R, 503A, 504L, 506P, 509F, 514T, 691E, 709H, 710H, 711N, 713S, 776V, 777M, 778S, 779Y, 782Y, 784I, 785E, 786D, 941K, 943V, 945G, 967N, 969H, 972P, 975M, 980M, 984V, 1,001F, 1,028S, 1,036Q, 1,037A, 1,038Y, 1,040F, 1,053V, 1,056K, 1,057M, 1,058H, 1,060R, 1,061A, 1,082L, 1,083R, 1,084L, 1,088E, 1,090D, 1,091C, 1,093I, 1,095Y, 1,096G, 1,097A, 1,098S, 1,099Q, 1,100L, 1,102L, 1,103E, 1,104R, 1,105L, 1,106M, 1,107L, 1,111A, 1,144P, 1,148K, 1,150L, 1,152Q, 1,153E, 1,155I, 1,157M, 1,158N, 1,159I, 1,160A, 1,162R, 1,164K
CDD
cd00653 (RNA_pol_B_RPB2)

778S

RPB1 interaction site
500G, 502R, 503A, 504L, 506P, 509F, 514T, 691E, 709H, 710H, 711N, 713S, 776V, 777M, 778S, 779Y, 782Y, 784I, 785E, 786D, 941K, 943V, 945G, 967N, 969H, 972P, 975M, 980M, 984V, 1,001F, 1,028S, 1,036Q, 1,037A, 1,038Y, 1,040F, 1,053V, 1,056K, 1,057M, 1,058H, 1,060R, 1,061A, 1,082L, 1,083R, 1,084L, 1,088E, 1,090D, 1,091C, 1,093I, 1,095Y, 1,096G, 1,097A, 1,098S, 1,099Q, 1,100L, 1,102L, 1,103E, 1,104R, 1,105L, 1,106M, 1,107L, 1,111A, 1,144P, 1,148K, 1,150L, 1,152Q, 1,153E, 1,155I, 1,157M, 1,158N, 1,159I, 1,160A, 1,162R, 1,164K
CDD
cd00653 (RNA_pol_B_RPB2)

779Y

RPB1 interaction site
500G, 502R, 503A, 504L, 506P, 509F, 514T, 691E, 709H, 710H, 711N, 713S, 776V, 777M, 778S, 779Y, 782Y, 784I, 785E, 786D, 941K, 943V, 945G, 967N, 969H, 972P, 975M, 980M, 984V, 1,001F, 1,028S, 1,036Q, 1,037A, 1,038Y, 1,040F, 1,053V, 1,056K, 1,057M, 1,058H, 1,060R, 1,061A, 1,082L, 1,083R, 1,084L, 1,088E, 1,090D, 1,091C, 1,093I, 1,095Y, 1,096G, 1,097A, 1,098S, 1,099Q, 1,100L, 1,102L, 1,103E, 1,104R, 1,105L, 1,106M, 1,107L, 1,111A, 1,144P, 1,148K, 1,150L, 1,152Q, 1,153E, 1,155I, 1,157M, 1,158N, 1,159I, 1,160A, 1,162R, 1,164K
CDD
cd00653 (RNA_pol_B_RPB2)

782Y

RPB1 interaction site
500G, 502R, 503A, 504L, 506P, 509F, 514T, 691E, 709H, 710H, 711N, 713S, 776V, 777M, 778S, 779Y, 782Y, 784I, 785E, 786D, 941K, 943V, 945G, 967N, 969H, 972P, 975M, 980M, 984V, 1,001F, 1,028S, 1,036Q, 1,037A, 1,038Y, 1,040F, 1,053V, 1,056K, 1,057M, 1,058H, 1,060R, 1,061A, 1,082L, 1,083R, 1,084L, 1,088E, 1,090D, 1,091C, 1,093I, 1,095Y, 1,096G, 1,097A, 1,098S, 1,099Q, 1,100L, 1,102L, 1,103E, 1,104R, 1,105L, 1,106M, 1,107L, 1,111A, 1,144P, 1,148K, 1,150L, 1,152Q, 1,153E, 1,155I, 1,157M, 1,158N, 1,159I, 1,160A, 1,162R, 1,164K
CDD
cd00653 (RNA_pol_B_RPB2)

784I

RPB1 interaction site
500G, 502R, 503A, 504L, 506P, 509F, 514T, 691E, 709H, 710H, 711N, 713S, 776V, 777M, 778S, 779Y, 782Y, 784I, 785E, 786D, 941K, 943V, 945G, 967N, 969H, 972P, 975M, 980M, 984V, 1,001F, 1,028S, 1,036Q, 1,037A, 1,038Y, 1,040F, 1,053V, 1,056K, 1,057M, 1,058H, 1,060R, 1,061A, 1,082L, 1,083R, 1,084L, 1,088E, 1,090D, 1,091C, 1,093I, 1,095Y, 1,096G, 1,097A, 1,098S, 1,099Q, 1,100L, 1,102L, 1,103E, 1,104R, 1,105L, 1,106M, 1,107L, 1,111A, 1,144P, 1,148K, 1,150L, 1,152Q, 1,153E, 1,155I, 1,157M, 1,158N, 1,159I, 1,160A, 1,162R, 1,164K
CDD
cd00653 (RNA_pol_B_RPB2)

785E

RPB1 interaction site
500G, 502R, 503A, 504L, 506P, 509F, 514T, 691E, 709H, 710H, 711N, 713S, 776V, 777M, 778S, 779Y, 782Y, 784I, 785E, 786D, 941K, 943V, 945G, 967N, 969H, 972P, 975M, 980M, 984V, 1,001F, 1,028S, 1,036Q, 1,037A, 1,038Y, 1,040F, 1,053V, 1,056K, 1,057M, 1,058H, 1,060R, 1,061A, 1,082L, 1,083R, 1,084L, 1,088E, 1,090D, 1,091C, 1,093I, 1,095Y, 1,096G, 1,097A, 1,098S, 1,099Q, 1,100L, 1,102L, 1,103E, 1,104R, 1,105L, 1,106M, 1,107L, 1,111A, 1,144P, 1,148K, 1,150L, 1,152Q, 1,153E, 1,155I, 1,157M, 1,158N, 1,159I, 1,160A, 1,162R, 1,164K
CDD
cd00653 (RNA_pol_B_RPB2)

786D

RPB1 interaction site
500G, 502R, 503A, 504L, 506P, 509F, 514T, 691E, 709H, 710H, 711N, 713S, 776V, 777M, 778S, 779Y, 782Y, 784I, 785E, 786D, 941K, 943V, 945G, 967N, 969H, 972P, 975M, 980M, 984V, 1,001F, 1,028S, 1,036Q, 1,037A, 1,038Y, 1,040F, 1,053V, 1,056K, 1,057M, 1,058H, 1,060R, 1,061A, 1,082L, 1,083R, 1,084L, 1,088E, 1,090D, 1,091C, 1,093I, 1,095Y, 1,096G, 1,097A, 1,098S, 1,099Q, 1,100L, 1,102L, 1,103E, 1,104R, 1,105L, 1,106M, 1,107L, 1,111A, 1,144P, 1,148K, 1,150L, 1,152Q, 1,153E, 1,155I, 1,157M, 1,158N, 1,159I, 1,160A, 1,162R, 1,164K
CDD
cd00653 (RNA_pol_B_RPB2)

941K

RPB1 interaction site
500G, 502R, 503A, 504L, 506P, 509F, 514T, 691E, 709H, 710H, 711N, 713S, 776V, 777M, 778S, 779Y, 782Y, 784I, 785E, 786D, 941K, 943V, 945G, 967N, 969H, 972P, 975M, 980M, 984V, 1,001F, 1,028S, 1,036Q, 1,037A, 1,038Y, 1,040F, 1,053V, 1,056K, 1,057M, 1,058H, 1,060R, 1,061A, 1,082L, 1,083R, 1,084L, 1,088E, 1,090D, 1,091C, 1,093I, 1,095Y, 1,096G, 1,097A, 1,098S, 1,099Q, 1,100L, 1,102L, 1,103E, 1,104R, 1,105L, 1,106M, 1,107L, 1,111A, 1,144P, 1,148K, 1,150L, 1,152Q, 1,153E, 1,155I, 1,157M, 1,158N, 1,159I, 1,160A, 1,162R, 1,164K
CDD
cd00653 (RNA_pol_B_RPB2)

943V

RPB1 interaction site
500G, 502R, 503A, 504L, 506P, 509F, 514T, 691E, 709H, 710H, 711N, 713S, 776V, 777M, 778S, 779Y, 782Y, 784I, 785E, 786D, 941K, 943V, 945G, 967N, 969H, 972P, 975M, 980M, 984V, 1,001F, 1,028S, 1,036Q, 1,037A, 1,038Y, 1,040F, 1,053V, 1,056K, 1,057M, 1,058H, 1,060R, 1,061A, 1,082L, 1,083R, 1,084L, 1,088E, 1,090D, 1,091C, 1,093I, 1,095Y, 1,096G, 1,097A, 1,098S, 1,099Q, 1,100L, 1,102L, 1,103E, 1,104R, 1,105L, 1,106M, 1,107L, 1,111A, 1,144P, 1,148K, 1,150L, 1,152Q, 1,153E, 1,155I, 1,157M, 1,158N, 1,159I, 1,160A, 1,162R, 1,164K
CDD
cd00653 (RNA_pol_B_RPB2)

945G

RPB1 interaction site
500G, 502R, 503A, 504L, 506P, 509F, 514T, 691E, 709H, 710H, 711N, 713S, 776V, 777M, 778S, 779Y, 782Y, 784I, 785E, 786D, 941K, 943V, 945G, 967N, 969H, 972P, 975M, 980M, 984V, 1,001F, 1,028S, 1,036Q, 1,037A, 1,038Y, 1,040F, 1,053V, 1,056K, 1,057M, 1,058H, 1,060R, 1,061A, 1,082L, 1,083R, 1,084L, 1,088E, 1,090D, 1,091C, 1,093I, 1,095Y, 1,096G, 1,097A, 1,098S, 1,099Q, 1,100L, 1,102L, 1,103E, 1,104R, 1,105L, 1,106M, 1,107L, 1,111A, 1,144P, 1,148K, 1,150L, 1,152Q, 1,153E, 1,155I, 1,157M, 1,158N, 1,159I, 1,160A, 1,162R, 1,164K
CDD
cd00653 (RNA_pol_B_RPB2)

967N

RPB1 interaction site
500G, 502R, 503A, 504L, 506P, 509F, 514T, 691E, 709H, 710H, 711N, 713S, 776V, 777M, 778S, 779Y, 782Y, 784I, 785E, 786D, 941K, 943V, 945G, 967N, 969H, 972P, 975M, 980M, 984V, 1,001F, 1,028S, 1,036Q, 1,037A, 1,038Y, 1,040F, 1,053V, 1,056K, 1,057M, 1,058H, 1,060R, 1,061A, 1,082L, 1,083R, 1,084L, 1,088E, 1,090D, 1,091C, 1,093I, 1,095Y, 1,096G, 1,097A, 1,098S, 1,099Q, 1,100L, 1,102L, 1,103E, 1,104R, 1,105L, 1,106M, 1,107L, 1,111A, 1,144P, 1,148K, 1,150L, 1,152Q, 1,153E, 1,155I, 1,157M, 1,158N, 1,159I, 1,160A, 1,162R, 1,164K
CDD
cd00653 (RNA_pol_B_RPB2)

969H

RPB1 interaction site
500G, 502R, 503A, 504L, 506P, 509F, 514T, 691E, 709H, 710H, 711N, 713S, 776V, 777M, 778S, 779Y, 782Y, 784I, 785E, 786D, 941K, 943V, 945G, 967N, 969H, 972P, 975M, 980M, 984V, 1,001F, 1,028S, 1,036Q, 1,037A, 1,038Y, 1,040F, 1,053V, 1,056K, 1,057M, 1,058H, 1,060R, 1,061A, 1,082L, 1,083R, 1,084L, 1,088E, 1,090D, 1,091C, 1,093I, 1,095Y, 1,096G, 1,097A, 1,098S, 1,099Q, 1,100L, 1,102L, 1,103E, 1,104R, 1,105L, 1,106M, 1,107L, 1,111A, 1,144P, 1,148K, 1,150L, 1,152Q, 1,153E, 1,155I, 1,157M, 1,158N, 1,159I, 1,160A, 1,162R, 1,164K
CDD
cd00653 (RNA_pol_B_RPB2)

972P

RPB1 interaction site
500G, 502R, 503A, 504L, 506P, 509F, 514T, 691E, 709H, 710H, 711N, 713S, 776V, 777M, 778S, 779Y, 782Y, 784I, 785E, 786D, 941K, 943V, 945G, 967N, 969H, 972P, 975M, 980M, 984V, 1,001F, 1,028S, 1,036Q, 1,037A, 1,038Y, 1,040F, 1,053V, 1,056K, 1,057M, 1,058H, 1,060R, 1,061A, 1,082L, 1,083R, 1,084L, 1,088E, 1,090D, 1,091C, 1,093I, 1,095Y, 1,096G, 1,097A, 1,098S, 1,099Q, 1,100L, 1,102L, 1,103E, 1,104R, 1,105L, 1,106M, 1,107L, 1,111A, 1,144P, 1,148K, 1,150L, 1,152Q, 1,153E, 1,155I, 1,157M, 1,158N, 1,159I, 1,160A, 1,162R, 1,164K
CDD
cd00653 (RNA_pol_B_RPB2)

975M

RPB1 interaction site
500G, 502R, 503A, 504L, 506P, 509F, 514T, 691E, 709H, 710H, 711N, 713S, 776V, 777M, 778S, 779Y, 782Y, 784I, 785E, 786D, 941K, 943V, 945G, 967N, 969H, 972P, 975M, 980M, 984V, 1,001F, 1,028S, 1,036Q, 1,037A, 1,038Y, 1,040F, 1,053V, 1,056K, 1,057M, 1,058H, 1,060R, 1,061A, 1,082L, 1,083R, 1,084L, 1,088E, 1,090D, 1,091C, 1,093I, 1,095Y, 1,096G, 1,097A, 1,098S, 1,099Q, 1,100L, 1,102L, 1,103E, 1,104R, 1,105L, 1,106M, 1,107L, 1,111A, 1,144P, 1,148K, 1,150L, 1,152Q, 1,153E, 1,155I, 1,157M, 1,158N, 1,159I, 1,160A, 1,162R, 1,164K
CDD
cd00653 (RNA_pol_B_RPB2)

980M

RPB1 interaction site
500G, 502R, 503A, 504L, 506P, 509F, 514T, 691E, 709H, 710H, 711N, 713S, 776V, 777M, 778S, 779Y, 782Y, 784I, 785E, 786D, 941K, 943V, 945G, 967N, 969H, 972P, 975M, 980M, 984V, 1,001F, 1,028S, 1,036Q, 1,037A, 1,038Y, 1,040F, 1,053V, 1,056K, 1,057M, 1,058H, 1,060R, 1,061A, 1,082L, 1,083R, 1,084L, 1,088E, 1,090D, 1,091C, 1,093I, 1,095Y, 1,096G, 1,097A, 1,098S, 1,099Q, 1,100L, 1,102L, 1,103E, 1,104R, 1,105L, 1,106M, 1,107L, 1,111A, 1,144P, 1,148K, 1,150L, 1,152Q, 1,153E, 1,155I, 1,157M, 1,158N, 1,159I, 1,160A, 1,162R, 1,164K
CDD
cd00653 (RNA_pol_B_RPB2)

984V

RPB1 interaction site
500G, 502R, 503A, 504L, 506P, 509F, 514T, 691E, 709H, 710H, 711N, 713S, 776V, 777M, 778S, 779Y, 782Y, 784I, 785E, 786D, 941K, 943V, 945G, 967N, 969H, 972P, 975M, 980M, 984V, 1,001F, 1,028S, 1,036Q, 1,037A, 1,038Y, 1,040F, 1,053V, 1,056K, 1,057M, 1,058H, 1,060R, 1,061A, 1,082L, 1,083R, 1,084L, 1,088E, 1,090D, 1,091C, 1,093I, 1,095Y, 1,096G, 1,097A, 1,098S, 1,099Q, 1,100L, 1,102L, 1,103E, 1,104R, 1,105L, 1,106M, 1,107L, 1,111A, 1,144P, 1,148K, 1,150L, 1,152Q, 1,153E, 1,155I, 1,157M, 1,158N, 1,159I, 1,160A, 1,162R, 1,164K
CDD
cd00653 (RNA_pol_B_RPB2)

1,001F

RPB1 interaction site
500G, 502R, 503A, 504L, 506P, 509F, 514T, 691E, 709H, 710H, 711N, 713S, 776V, 777M, 778S, 779Y, 782Y, 784I, 785E, 786D, 941K, 943V, 945G, 967N, 969H, 972P, 975M, 980M, 984V, 1,001F, 1,028S, 1,036Q, 1,037A, 1,038Y, 1,040F, 1,053V, 1,056K, 1,057M, 1,058H, 1,060R, 1,061A, 1,082L, 1,083R, 1,084L, 1,088E, 1,090D, 1,091C, 1,093I, 1,095Y, 1,096G, 1,097A, 1,098S, 1,099Q, 1,100L, 1,102L, 1,103E, 1,104R, 1,105L, 1,106M, 1,107L, 1,111A, 1,144P, 1,148K, 1,150L, 1,152Q, 1,153E, 1,155I, 1,157M, 1,158N, 1,159I, 1,160A, 1,162R, 1,164K
CDD
cd00653 (RNA_pol_B_RPB2)

1,028S

RPB1 interaction site
500G, 502R, 503A, 504L, 506P, 509F, 514T, 691E, 709H, 710H, 711N, 713S, 776V, 777M, 778S, 779Y, 782Y, 784I, 785E, 786D, 941K, 943V, 945G, 967N, 969H, 972P, 975M, 980M, 984V, 1,001F, 1,028S, 1,036Q, 1,037A, 1,038Y, 1,040F, 1,053V, 1,056K, 1,057M, 1,058H, 1,060R, 1,061A, 1,082L, 1,083R, 1,084L, 1,088E, 1,090D, 1,091C, 1,093I, 1,095Y, 1,096G, 1,097A, 1,098S, 1,099Q, 1,100L, 1,102L, 1,103E, 1,104R, 1,105L, 1,106M, 1,107L, 1,111A, 1,144P, 1,148K, 1,150L, 1,152Q, 1,153E, 1,155I, 1,157M, 1,158N, 1,159I, 1,160A, 1,162R, 1,164K
CDD
cd00653 (RNA_pol_B_RPB2)

1,036Q

RPB1 interaction site
500G, 502R, 503A, 504L, 506P, 509F, 514T, 691E, 709H, 710H, 711N, 713S, 776V, 777M, 778S, 779Y, 782Y, 784I, 785E, 786D, 941K, 943V, 945G, 967N, 969H, 972P, 975M, 980M, 984V, 1,001F, 1,028S, 1,036Q, 1,037A, 1,038Y, 1,040F, 1,053V, 1,056K, 1,057M, 1,058H, 1,060R, 1,061A, 1,082L, 1,083R, 1,084L, 1,088E, 1,090D, 1,091C, 1,093I, 1,095Y, 1,096G, 1,097A, 1,098S, 1,099Q, 1,100L, 1,102L, 1,103E, 1,104R, 1,105L, 1,106M, 1,107L, 1,111A, 1,144P, 1,148K, 1,150L, 1,152Q, 1,153E, 1,155I, 1,157M, 1,158N, 1,159I, 1,160A, 1,162R, 1,164K
CDD
cd00653 (RNA_pol_B_RPB2)

1,037A

RPB1 interaction site
500G, 502R, 503A, 504L, 506P, 509F, 514T, 691E, 709H, 710H, 711N, 713S, 776V, 777M, 778S, 779Y, 782Y, 784I, 785E, 786D, 941K, 943V, 945G, 967N, 969H, 972P, 975M, 980M, 984V, 1,001F, 1,028S, 1,036Q, 1,037A, 1,038Y, 1,040F, 1,053V, 1,056K, 1,057M, 1,058H, 1,060R, 1,061A, 1,082L, 1,083R, 1,084L, 1,088E, 1,090D, 1,091C, 1,093I, 1,095Y, 1,096G, 1,097A, 1,098S, 1,099Q, 1,100L, 1,102L, 1,103E, 1,104R, 1,105L, 1,106M, 1,107L, 1,111A, 1,144P, 1,148K, 1,150L, 1,152Q, 1,153E, 1,155I, 1,157M, 1,158N, 1,159I, 1,160A, 1,162R, 1,164K
CDD
cd00653 (RNA_pol_B_RPB2)

1,038Y

RPB1 interaction site
500G, 502R, 503A, 504L, 506P, 509F, 514T, 691E, 709H, 710H, 711N, 713S, 776V, 777M, 778S, 779Y, 782Y, 784I, 785E, 786D, 941K, 943V, 945G, 967N, 969H, 972P, 975M, 980M, 984V, 1,001F, 1,028S, 1,036Q, 1,037A, 1,038Y, 1,040F, 1,053V, 1,056K, 1,057M, 1,058H, 1,060R, 1,061A, 1,082L, 1,083R, 1,084L, 1,088E, 1,090D, 1,091C, 1,093I, 1,095Y, 1,096G, 1,097A, 1,098S, 1,099Q, 1,100L, 1,102L, 1,103E, 1,104R, 1,105L, 1,106M, 1,107L, 1,111A, 1,144P, 1,148K, 1,150L, 1,152Q, 1,153E, 1,155I, 1,157M, 1,158N, 1,159I, 1,160A, 1,162R, 1,164K
CDD
cd00653 (RNA_pol_B_RPB2)

1,040F

RPB1 interaction site
500G, 502R, 503A, 504L, 506P, 509F, 514T, 691E, 709H, 710H, 711N, 713S, 776V, 777M, 778S, 779Y, 782Y, 784I, 785E, 786D, 941K, 943V, 945G, 967N, 969H, 972P, 975M, 980M, 984V, 1,001F, 1,028S, 1,036Q, 1,037A, 1,038Y, 1,040F, 1,053V, 1,056K, 1,057M, 1,058H, 1,060R, 1,061A, 1,082L, 1,083R, 1,084L, 1,088E, 1,090D, 1,091C, 1,093I, 1,095Y, 1,096G, 1,097A, 1,098S, 1,099Q, 1,100L, 1,102L, 1,103E, 1,104R, 1,105L, 1,106M, 1,107L, 1,111A, 1,144P, 1,148K, 1,150L, 1,152Q, 1,153E, 1,155I, 1,157M, 1,158N, 1,159I, 1,160A, 1,162R, 1,164K
CDD
cd00653 (RNA_pol_B_RPB2)

1,053V

RPB1 interaction site
500G, 502R, 503A, 504L, 506P, 509F, 514T, 691E, 709H, 710H, 711N, 713S, 776V, 777M, 778S, 779Y, 782Y, 784I, 785E, 786D, 941K, 943V, 945G, 967N, 969H, 972P, 975M, 980M, 984V, 1,001F, 1,028S, 1,036Q, 1,037A, 1,038Y, 1,040F, 1,053V, 1,056K, 1,057M, 1,058H, 1,060R, 1,061A, 1,082L, 1,083R, 1,084L, 1,088E, 1,090D, 1,091C, 1,093I, 1,095Y, 1,096G, 1,097A, 1,098S, 1,099Q, 1,100L, 1,102L, 1,103E, 1,104R, 1,105L, 1,106M, 1,107L, 1,111A, 1,144P, 1,148K, 1,150L, 1,152Q, 1,153E, 1,155I, 1,157M, 1,158N, 1,159I, 1,160A, 1,162R, 1,164K
CDD
cd00653 (RNA_pol_B_RPB2)

1,056K

RPB1 interaction site
500G, 502R, 503A, 504L, 506P, 509F, 514T, 691E, 709H, 710H, 711N, 713S, 776V, 777M, 778S, 779Y, 782Y, 784I, 785E, 786D, 941K, 943V, 945G, 967N, 969H, 972P, 975M, 980M, 984V, 1,001F, 1,028S, 1,036Q, 1,037A, 1,038Y, 1,040F, 1,053V, 1,056K, 1,057M, 1,058H, 1,060R, 1,061A, 1,082L, 1,083R, 1,084L, 1,088E, 1,090D, 1,091C, 1,093I, 1,095Y, 1,096G, 1,097A, 1,098S, 1,099Q, 1,100L, 1,102L, 1,103E, 1,104R, 1,105L, 1,106M, 1,107L, 1,111A, 1,144P, 1,148K, 1,150L, 1,152Q, 1,153E, 1,155I, 1,157M, 1,158N, 1,159I, 1,160A, 1,162R, 1,164K
CDD
cd00653 (RNA_pol_B_RPB2)

1,057M

RPB1 interaction site
500G, 502R, 503A, 504L, 506P, 509F, 514T, 691E, 709H, 710H, 711N, 713S, 776V, 777M, 778S, 779Y, 782Y, 784I, 785E, 786D, 941K, 943V, 945G, 967N, 969H, 972P, 975M, 980M, 984V, 1,001F, 1,028S, 1,036Q, 1,037A, 1,038Y, 1,040F, 1,053V, 1,056K, 1,057M, 1,058H, 1,060R, 1,061A, 1,082L, 1,083R, 1,084L, 1,088E, 1,090D, 1,091C, 1,093I, 1,095Y, 1,096G, 1,097A, 1,098S, 1,099Q, 1,100L, 1,102L, 1,103E, 1,104R, 1,105L, 1,106M, 1,107L, 1,111A, 1,144P, 1,148K, 1,150L, 1,152Q, 1,153E, 1,155I, 1,157M, 1,158N, 1,159I, 1,160A, 1,162R, 1,164K
CDD
cd00653 (RNA_pol_B_RPB2)

1,058H

RPB1 interaction site
500G, 502R, 503A, 504L, 506P, 509F, 514T, 691E, 709H, 710H, 711N, 713S, 776V, 777M, 778S, 779Y, 782Y, 784I, 785E, 786D, 941K, 943V, 945G, 967N, 969H, 972P, 975M, 980M, 984V, 1,001F, 1,028S, 1,036Q, 1,037A, 1,038Y, 1,040F, 1,053V, 1,056K, 1,057M, 1,058H, 1,060R, 1,061A, 1,082L, 1,083R, 1,084L, 1,088E, 1,090D, 1,091C, 1,093I, 1,095Y, 1,096G, 1,097A, 1,098S, 1,099Q, 1,100L, 1,102L, 1,103E, 1,104R, 1,105L, 1,106M, 1,107L, 1,111A, 1,144P, 1,148K, 1,150L, 1,152Q, 1,153E, 1,155I, 1,157M, 1,158N, 1,159I, 1,160A, 1,162R, 1,164K
CDD
cd00653 (RNA_pol_B_RPB2)

1,060R

RPB1 interaction site
500G, 502R, 503A, 504L, 506P, 509F, 514T, 691E, 709H, 710H, 711N, 713S, 776V, 777M, 778S, 779Y, 782Y, 784I, 785E, 786D, 941K, 943V, 945G, 967N, 969H, 972P, 975M, 980M, 984V, 1,001F, 1,028S, 1,036Q, 1,037A, 1,038Y, 1,040F, 1,053V, 1,056K, 1,057M, 1,058H, 1,060R, 1,061A, 1,082L, 1,083R, 1,084L, 1,088E, 1,090D, 1,091C, 1,093I, 1,095Y, 1,096G, 1,097A, 1,098S, 1,099Q, 1,100L, 1,102L, 1,103E, 1,104R, 1,105L, 1,106M, 1,107L, 1,111A, 1,144P, 1,148K, 1,150L, 1,152Q, 1,153E, 1,155I, 1,157M, 1,158N, 1,159I, 1,160A, 1,162R, 1,164K
CDD
cd00653 (RNA_pol_B_RPB2)

1,061A

RPB1 interaction site
500G, 502R, 503A, 504L, 506P, 509F, 514T, 691E, 709H, 710H, 711N, 713S, 776V, 777M, 778S, 779Y, 782Y, 784I, 785E, 786D, 941K, 943V, 945G, 967N, 969H, 972P, 975M, 980M, 984V, 1,001F, 1,028S, 1,036Q, 1,037A, 1,038Y, 1,040F, 1,053V, 1,056K, 1,057M, 1,058H, 1,060R, 1,061A, 1,082L, 1,083R, 1,084L, 1,088E, 1,090D, 1,091C, 1,093I, 1,095Y, 1,096G, 1,097A, 1,098S, 1,099Q, 1,100L, 1,102L, 1,103E, 1,104R, 1,105L, 1,106M, 1,107L, 1,111A, 1,144P, 1,148K, 1,150L, 1,152Q, 1,153E, 1,155I, 1,157M, 1,158N, 1,159I, 1,160A, 1,162R, 1,164K
CDD
cd00653 (RNA_pol_B_RPB2)

1,082L

RPB1 interaction site
500G, 502R, 503A, 504L, 506P, 509F, 514T, 691E, 709H, 710H, 711N, 713S, 776V, 777M, 778S, 779Y, 782Y, 784I, 785E, 786D, 941K, 943V, 945G, 967N, 969H, 972P, 975M, 980M, 984V, 1,001F, 1,028S, 1,036Q, 1,037A, 1,038Y, 1,040F, 1,053V, 1,056K, 1,057M, 1,058H, 1,060R, 1,061A, 1,082L, 1,083R, 1,084L, 1,088E, 1,090D, 1,091C, 1,093I, 1,095Y, 1,096G, 1,097A, 1,098S, 1,099Q, 1,100L, 1,102L, 1,103E, 1,104R, 1,105L, 1,106M, 1,107L, 1,111A, 1,144P, 1,148K, 1,150L, 1,152Q, 1,153E, 1,155I, 1,157M, 1,158N, 1,159I, 1,160A, 1,162R, 1,164K
CDD
cd00653 (RNA_pol_B_RPB2)

1,083R

RPB1 interaction site
500G, 502R, 503A, 504L, 506P, 509F, 514T, 691E, 709H, 710H, 711N, 713S, 776V, 777M, 778S, 779Y, 782Y, 784I, 785E, 786D, 941K, 943V, 945G, 967N, 969H, 972P, 975M, 980M, 984V, 1,001F, 1,028S, 1,036Q, 1,037A, 1,038Y, 1,040F, 1,053V, 1,056K, 1,057M, 1,058H, 1,060R, 1,061A, 1,082L, 1,083R, 1,084L, 1,088E, 1,090D, 1,091C, 1,093I, 1,095Y, 1,096G, 1,097A, 1,098S, 1,099Q, 1,100L, 1,102L, 1,103E, 1,104R, 1,105L, 1,106M, 1,107L, 1,111A, 1,144P, 1,148K, 1,150L, 1,152Q, 1,153E, 1,155I, 1,157M, 1,158N, 1,159I, 1,160A, 1,162R, 1,164K
CDD
cd00653 (RNA_pol_B_RPB2)

1,084L

RPB1 interaction site
500G, 502R, 503A, 504L, 506P, 509F, 514T, 691E, 709H, 710H, 711N, 713S, 776V, 777M, 778S, 779Y, 782Y, 784I, 785E, 786D, 941K, 943V, 945G, 967N, 969H, 972P, 975M, 980M, 984V, 1,001F, 1,028S, 1,036Q, 1,037A, 1,038Y, 1,040F, 1,053V, 1,056K, 1,057M, 1,058H, 1,060R, 1,061A, 1,082L, 1,083R, 1,084L, 1,088E, 1,090D, 1,091C, 1,093I, 1,095Y, 1,096G, 1,097A, 1,098S, 1,099Q, 1,100L, 1,102L, 1,103E, 1,104R, 1,105L, 1,106M, 1,107L, 1,111A, 1,144P, 1,148K, 1,150L, 1,152Q, 1,153E, 1,155I, 1,157M, 1,158N, 1,159I, 1,160A, 1,162R, 1,164K
CDD
cd00653 (RNA_pol_B_RPB2)

1,088E

RPB1 interaction site
500G, 502R, 503A, 504L, 506P, 509F, 514T, 691E, 709H, 710H, 711N, 713S, 776V, 777M, 778S, 779Y, 782Y, 784I, 785E, 786D, 941K, 943V, 945G, 967N, 969H, 972P, 975M, 980M, 984V, 1,001F, 1,028S, 1,036Q, 1,037A, 1,038Y, 1,040F, 1,053V, 1,056K, 1,057M, 1,058H, 1,060R, 1,061A, 1,082L, 1,083R, 1,084L, 1,088E, 1,090D, 1,091C, 1,093I, 1,095Y, 1,096G, 1,097A, 1,098S, 1,099Q, 1,100L, 1,102L, 1,103E, 1,104R, 1,105L, 1,106M, 1,107L, 1,111A, 1,144P, 1,148K, 1,150L, 1,152Q, 1,153E, 1,155I, 1,157M, 1,158N, 1,159I, 1,160A, 1,162R, 1,164K
CDD
cd00653 (RNA_pol_B_RPB2)

1,090D

RPB1 interaction site
500G, 502R, 503A, 504L, 506P, 509F, 514T, 691E, 709H, 710H, 711N, 713S, 776V, 777M, 778S, 779Y, 782Y, 784I, 785E, 786D, 941K, 943V, 945G, 967N, 969H, 972P, 975M, 980M, 984V, 1,001F, 1,028S, 1,036Q, 1,037A, 1,038Y, 1,040F, 1,053V, 1,056K, 1,057M, 1,058H, 1,060R, 1,061A, 1,082L, 1,083R, 1,084L, 1,088E, 1,090D, 1,091C, 1,093I, 1,095Y, 1,096G, 1,097A, 1,098S, 1,099Q, 1,100L, 1,102L, 1,103E, 1,104R, 1,105L, 1,106M, 1,107L, 1,111A, 1,144P, 1,148K, 1,150L, 1,152Q, 1,153E, 1,155I, 1,157M, 1,158N, 1,159I, 1,160A, 1,162R, 1,164K
CDD
cd00653 (RNA_pol_B_RPB2)

1,091C

RPB1 interaction site
500G, 502R, 503A, 504L, 506P, 509F, 514T, 691E, 709H, 710H, 711N, 713S, 776V, 777M, 778S, 779Y, 782Y, 784I, 785E, 786D, 941K, 943V, 945G, 967N, 969H, 972P, 975M, 980M, 984V, 1,001F, 1,028S, 1,036Q, 1,037A, 1,038Y, 1,040F, 1,053V, 1,056K, 1,057M, 1,058H, 1,060R, 1,061A, 1,082L, 1,083R, 1,084L, 1,088E, 1,090D, 1,091C, 1,093I, 1,095Y, 1,096G, 1,097A, 1,098S, 1,099Q, 1,100L, 1,102L, 1,103E, 1,104R, 1,105L, 1,106M, 1,107L, 1,111A, 1,144P, 1,148K, 1,150L, 1,152Q, 1,153E, 1,155I, 1,157M, 1,158N, 1,159I, 1,160A, 1,162R, 1,164K
CDD
cd00653 (RNA_pol_B_RPB2)

1,093I

RPB1 interaction site
500G, 502R, 503A, 504L, 506P, 509F, 514T, 691E, 709H, 710H, 711N, 713S, 776V, 777M, 778S, 779Y, 782Y, 784I, 785E, 786D, 941K, 943V, 945G, 967N, 969H, 972P, 975M, 980M, 984V, 1,001F, 1,028S, 1,036Q, 1,037A, 1,038Y, 1,040F, 1,053V, 1,056K, 1,057M, 1,058H, 1,060R, 1,061A, 1,082L, 1,083R, 1,084L, 1,088E, 1,090D, 1,091C, 1,093I, 1,095Y, 1,096G, 1,097A, 1,098S, 1,099Q, 1,100L, 1,102L, 1,103E, 1,104R, 1,105L, 1,106M, 1,107L, 1,111A, 1,144P, 1,148K, 1,150L, 1,152Q, 1,153E, 1,155I, 1,157M, 1,158N, 1,159I, 1,160A, 1,162R, 1,164K
CDD
cd00653 (RNA_pol_B_RPB2)

1,095Y

RPB1 interaction site
500G, 502R, 503A, 504L, 506P, 509F, 514T, 691E, 709H, 710H, 711N, 713S, 776V, 777M, 778S, 779Y, 782Y, 784I, 785E, 786D, 941K, 943V, 945G, 967N, 969H, 972P, 975M, 980M, 984V, 1,001F, 1,028S, 1,036Q, 1,037A, 1,038Y, 1,040F, 1,053V, 1,056K, 1,057M, 1,058H, 1,060R, 1,061A, 1,082L, 1,083R, 1,084L, 1,088E, 1,090D, 1,091C, 1,093I, 1,095Y, 1,096G, 1,097A, 1,098S, 1,099Q, 1,100L, 1,102L, 1,103E, 1,104R, 1,105L, 1,106M, 1,107L, 1,111A, 1,144P, 1,148K, 1,150L, 1,152Q, 1,153E, 1,155I, 1,157M, 1,158N, 1,159I, 1,160A, 1,162R, 1,164K
CDD
cd00653 (RNA_pol_B_RPB2)

1,096G

RPB1 interaction site
500G, 502R, 503A, 504L, 506P, 509F, 514T, 691E, 709H, 710H, 711N, 713S, 776V, 777M, 778S, 779Y, 782Y, 784I, 785E, 786D, 941K, 943V, 945G, 967N, 969H, 972P, 975M, 980M, 984V, 1,001F, 1,028S, 1,036Q, 1,037A, 1,038Y, 1,040F, 1,053V, 1,056K, 1,057M, 1,058H, 1,060R, 1,061A, 1,082L, 1,083R, 1,084L, 1,088E, 1,090D, 1,091C, 1,093I, 1,095Y, 1,096G, 1,097A, 1,098S, 1,099Q, 1,100L, 1,102L, 1,103E, 1,104R, 1,105L, 1,106M, 1,107L, 1,111A, 1,144P, 1,148K, 1,150L, 1,152Q, 1,153E, 1,155I, 1,157M, 1,158N, 1,159I, 1,160A, 1,162R, 1,164K
CDD
cd00653 (RNA_pol_B_RPB2)

1,097A

RPB1 interaction site
500G, 502R, 503A, 504L, 506P, 509F, 514T, 691E, 709H, 710H, 711N, 713S, 776V, 777M, 778S, 779Y, 782Y, 784I, 785E, 786D, 941K, 943V, 945G, 967N, 969H, 972P, 975M, 980M, 984V, 1,001F, 1,028S, 1,036Q, 1,037A, 1,038Y, 1,040F, 1,053V, 1,056K, 1,057M, 1,058H, 1,060R, 1,061A, 1,082L, 1,083R, 1,084L, 1,088E, 1,090D, 1,091C, 1,093I, 1,095Y, 1,096G, 1,097A, 1,098S, 1,099Q, 1,100L, 1,102L, 1,103E, 1,104R, 1,105L, 1,106M, 1,107L, 1,111A, 1,144P, 1,148K, 1,150L, 1,152Q, 1,153E, 1,155I, 1,157M, 1,158N, 1,159I, 1,160A, 1,162R, 1,164K
CDD
cd00653 (RNA_pol_B_RPB2)

1,098S

RPB1 interaction site
500G, 502R, 503A, 504L, 506P, 509F, 514T, 691E, 709H, 710H, 711N, 713S, 776V, 777M, 778S, 779Y, 782Y, 784I, 785E, 786D, 941K, 943V, 945G, 967N, 969H, 972P, 975M, 980M, 984V, 1,001F, 1,028S, 1,036Q, 1,037A, 1,038Y, 1,040F, 1,053V, 1,056K, 1,057M, 1,058H, 1,060R, 1,061A, 1,082L, 1,083R, 1,084L, 1,088E, 1,090D, 1,091C, 1,093I, 1,095Y, 1,096G, 1,097A, 1,098S, 1,099Q, 1,100L, 1,102L, 1,103E, 1,104R, 1,105L, 1,106M, 1,107L, 1,111A, 1,144P, 1,148K, 1,150L, 1,152Q, 1,153E, 1,155I, 1,157M, 1,158N, 1,159I, 1,160A, 1,162R, 1,164K
CDD
cd00653 (RNA_pol_B_RPB2)

1,099Q

RPB1 interaction site
500G, 502R, 503A, 504L, 506P, 509F, 514T, 691E, 709H, 710H, 711N, 713S, 776V, 777M, 778S, 779Y, 782Y, 784I, 785E, 786D, 941K, 943V, 945G, 967N, 969H, 972P, 975M, 980M, 984V, 1,001F, 1,028S, 1,036Q, 1,037A, 1,038Y, 1,040F, 1,053V, 1,056K, 1,057M, 1,058H, 1,060R, 1,061A, 1,082L, 1,083R, 1,084L, 1,088E, 1,090D, 1,091C, 1,093I, 1,095Y, 1,096G, 1,097A, 1,098S, 1,099Q, 1,100L, 1,102L, 1,103E, 1,104R, 1,105L, 1,106M, 1,107L, 1,111A, 1,144P, 1,148K, 1,150L, 1,152Q, 1,153E, 1,155I, 1,157M, 1,158N, 1,159I, 1,160A, 1,162R, 1,164K
CDD
cd00653 (RNA_pol_B_RPB2)

1,100L

RPB1 interaction site
500G, 502R, 503A, 504L, 506P, 509F, 514T, 691E, 709H, 710H, 711N, 713S, 776V, 777M, 778S, 779Y, 782Y, 784I, 785E, 786D, 941K, 943V, 945G, 967N, 969H, 972P, 975M, 980M, 984V, 1,001F, 1,028S, 1,036Q, 1,037A, 1,038Y, 1,040F, 1,053V, 1,056K, 1,057M, 1,058H, 1,060R, 1,061A, 1,082L, 1,083R, 1,084L, 1,088E, 1,090D, 1,091C, 1,093I, 1,095Y, 1,096G, 1,097A, 1,098S, 1,099Q, 1,100L, 1,102L, 1,103E, 1,104R, 1,105L, 1,106M, 1,107L, 1,111A, 1,144P, 1,148K, 1,150L, 1,152Q, 1,153E, 1,155I, 1,157M, 1,158N, 1,159I, 1,160A, 1,162R, 1,164K
CDD
cd00653 (RNA_pol_B_RPB2)

1,102L

RPB1 interaction site
500G, 502R, 503A, 504L, 506P, 509F, 514T, 691E, 709H, 710H, 711N, 713S, 776V, 777M, 778S, 779Y, 782Y, 784I, 785E, 786D, 941K, 943V, 945G, 967N, 969H, 972P, 975M, 980M, 984V, 1,001F, 1,028S, 1,036Q, 1,037A, 1,038Y, 1,040F, 1,053V, 1,056K, 1,057M, 1,058H, 1,060R, 1,061A, 1,082L, 1,083R, 1,084L, 1,088E, 1,090D, 1,091C, 1,093I, 1,095Y, 1,096G, 1,097A, 1,098S, 1,099Q, 1,100L, 1,102L, 1,103E, 1,104R, 1,105L, 1,106M, 1,107L, 1,111A, 1,144P, 1,148K, 1,150L, 1,152Q, 1,153E, 1,155I, 1,157M, 1,158N, 1,159I, 1,160A, 1,162R, 1,164K
CDD
cd00653 (RNA_pol_B_RPB2)

1,103E

RPB1 interaction site
500G, 502R, 503A, 504L, 506P, 509F, 514T, 691E, 709H, 710H, 711N, 713S, 776V, 777M, 778S, 779Y, 782Y, 784I, 785E, 786D, 941K, 943V, 945G, 967N, 969H, 972P, 975M, 980M, 984V, 1,001F, 1,028S, 1,036Q, 1,037A, 1,038Y, 1,040F, 1,053V, 1,056K, 1,057M, 1,058H, 1,060R, 1,061A, 1,082L, 1,083R, 1,084L, 1,088E, 1,090D, 1,091C, 1,093I, 1,095Y, 1,096G, 1,097A, 1,098S, 1,099Q, 1,100L, 1,102L, 1,103E, 1,104R, 1,105L, 1,106M, 1,107L, 1,111A, 1,144P, 1,148K, 1,150L, 1,152Q, 1,153E, 1,155I, 1,157M, 1,158N, 1,159I, 1,160A, 1,162R, 1,164K
CDD
cd00653 (RNA_pol_B_RPB2)

1,104R

RPB1 interaction site
500G, 502R, 503A, 504L, 506P, 509F, 514T, 691E, 709H, 710H, 711N, 713S, 776V, 777M, 778S, 779Y, 782Y, 784I, 785E, 786D, 941K, 943V, 945G, 967N, 969H, 972P, 975M, 980M, 984V, 1,001F, 1,028S, 1,036Q, 1,037A, 1,038Y, 1,040F, 1,053V, 1,056K, 1,057M, 1,058H, 1,060R, 1,061A, 1,082L, 1,083R, 1,084L, 1,088E, 1,090D, 1,091C, 1,093I, 1,095Y, 1,096G, 1,097A, 1,098S, 1,099Q, 1,100L, 1,102L, 1,103E, 1,104R, 1,105L, 1,106M, 1,107L, 1,111A, 1,144P, 1,148K, 1,150L, 1,152Q, 1,153E, 1,155I, 1,157M, 1,158N, 1,159I, 1,160A, 1,162R, 1,164K
CDD
cd00653 (RNA_pol_B_RPB2)

1,105L

RPB1 interaction site
500G, 502R, 503A, 504L, 506P, 509F, 514T, 691E, 709H, 710H, 711N, 713S, 776V, 777M, 778S, 779Y, 782Y, 784I, 785E, 786D, 941K, 943V, 945G, 967N, 969H, 972P, 975M, 980M, 984V, 1,001F, 1,028S, 1,036Q, 1,037A, 1,038Y, 1,040F, 1,053V, 1,056K, 1,057M, 1,058H, 1,060R, 1,061A, 1,082L, 1,083R, 1,084L, 1,088E, 1,090D, 1,091C, 1,093I, 1,095Y, 1,096G, 1,097A, 1,098S, 1,099Q, 1,100L, 1,102L, 1,103E, 1,104R, 1,105L, 1,106M, 1,107L, 1,111A, 1,144P, 1,148K, 1,150L, 1,152Q, 1,153E, 1,155I, 1,157M, 1,158N, 1,159I, 1,160A, 1,162R, 1,164K
CDD
cd00653 (RNA_pol_B_RPB2)

1,106M

RPB1 interaction site
500G, 502R, 503A, 504L, 506P, 509F, 514T, 691E, 709H, 710H, 711N, 713S, 776V, 777M, 778S, 779Y, 782Y, 784I, 785E, 786D, 941K, 943V, 945G, 967N, 969H, 972P, 975M, 980M, 984V, 1,001F, 1,028S, 1,036Q, 1,037A, 1,038Y, 1,040F, 1,053V, 1,056K, 1,057M, 1,058H, 1,060R, 1,061A, 1,082L, 1,083R, 1,084L, 1,088E, 1,090D, 1,091C, 1,093I, 1,095Y, 1,096G, 1,097A, 1,098S, 1,099Q, 1,100L, 1,102L, 1,103E, 1,104R, 1,105L, 1,106M, 1,107L, 1,111A, 1,144P, 1,148K, 1,150L, 1,152Q, 1,153E, 1,155I, 1,157M, 1,158N, 1,159I, 1,160A, 1,162R, 1,164K
CDD
cd00653 (RNA_pol_B_RPB2)

1,107L

RPB1 interaction site
500G, 502R, 503A, 504L, 506P, 509F, 514T, 691E, 709H, 710H, 711N, 713S, 776V, 777M, 778S, 779Y, 782Y, 784I, 785E, 786D, 941K, 943V, 945G, 967N, 969H, 972P, 975M, 980M, 984V, 1,001F, 1,028S, 1,036Q, 1,037A, 1,038Y, 1,040F, 1,053V, 1,056K, 1,057M, 1,058H, 1,060R, 1,061A, 1,082L, 1,083R, 1,084L, 1,088E, 1,090D, 1,091C, 1,093I, 1,095Y, 1,096G, 1,097A, 1,098S, 1,099Q, 1,100L, 1,102L, 1,103E, 1,104R, 1,105L, 1,106M, 1,107L, 1,111A, 1,144P, 1,148K, 1,150L, 1,152Q, 1,153E, 1,155I, 1,157M, 1,158N, 1,159I, 1,160A, 1,162R, 1,164K
CDD
cd00653 (RNA_pol_B_RPB2)

1,111A

RPB1 interaction site
500G, 502R, 503A, 504L, 506P, 509F, 514T, 691E, 709H, 710H, 711N, 713S, 776V, 777M, 778S, 779Y, 782Y, 784I, 785E, 786D, 941K, 943V, 945G, 967N, 969H, 972P, 975M, 980M, 984V, 1,001F, 1,028S, 1,036Q, 1,037A, 1,038Y, 1,040F, 1,053V, 1,056K, 1,057M, 1,058H, 1,060R, 1,061A, 1,082L, 1,083R, 1,084L, 1,088E, 1,090D, 1,091C, 1,093I, 1,095Y, 1,096G, 1,097A, 1,098S, 1,099Q, 1,100L, 1,102L, 1,103E, 1,104R, 1,105L, 1,106M, 1,107L, 1,111A, 1,144P, 1,148K, 1,150L, 1,152Q, 1,153E, 1,155I, 1,157M, 1,158N, 1,159I, 1,160A, 1,162R, 1,164K
CDD
cd00653 (RNA_pol_B_RPB2)

1,144P

RPB1 interaction site
500G, 502R, 503A, 504L, 506P, 509F, 514T, 691E, 709H, 710H, 711N, 713S, 776V, 777M, 778S, 779Y, 782Y, 784I, 785E, 786D, 941K, 943V, 945G, 967N, 969H, 972P, 975M, 980M, 984V, 1,001F, 1,028S, 1,036Q, 1,037A, 1,038Y, 1,040F, 1,053V, 1,056K, 1,057M, 1,058H, 1,060R, 1,061A, 1,082L, 1,083R, 1,084L, 1,088E, 1,090D, 1,091C, 1,093I, 1,095Y, 1,096G, 1,097A, 1,098S, 1,099Q, 1,100L, 1,102L, 1,103E, 1,104R, 1,105L, 1,106M, 1,107L, 1,111A, 1,144P, 1,148K, 1,150L, 1,152Q, 1,153E, 1,155I, 1,157M, 1,158N, 1,159I, 1,160A, 1,162R, 1,164K
CDD
cd00653 (RNA_pol_B_RPB2)

1,148K

RPB1 interaction site
500G, 502R, 503A, 504L, 506P, 509F, 514T, 691E, 709H, 710H, 711N, 713S, 776V, 777M, 778S, 779Y, 782Y, 784I, 785E, 786D, 941K, 943V, 945G, 967N, 969H, 972P, 975M, 980M, 984V, 1,001F, 1,028S, 1,036Q, 1,037A, 1,038Y, 1,040F, 1,053V, 1,056K, 1,057M, 1,058H, 1,060R, 1,061A, 1,082L, 1,083R, 1,084L, 1,088E, 1,090D, 1,091C, 1,093I, 1,095Y, 1,096G, 1,097A, 1,098S, 1,099Q, 1,100L, 1,102L, 1,103E, 1,104R, 1,105L, 1,106M, 1,107L, 1,111A, 1,144P, 1,148K, 1,150L, 1,152Q, 1,153E, 1,155I, 1,157M, 1,158N, 1,159I, 1,160A, 1,162R, 1,164K
CDD
cd00653 (RNA_pol_B_RPB2)

1,150L

RPB1 interaction site
500G, 502R, 503A, 504L, 506P, 509F, 514T, 691E, 709H, 710H, 711N, 713S, 776V, 777M, 778S, 779Y, 782Y, 784I, 785E, 786D, 941K, 943V, 945G, 967N, 969H, 972P, 975M, 980M, 984V, 1,001F, 1,028S, 1,036Q, 1,037A, 1,038Y, 1,040F, 1,053V, 1,056K, 1,057M, 1,058H, 1,060R, 1,061A, 1,082L, 1,083R, 1,084L, 1,088E, 1,090D, 1,091C, 1,093I, 1,095Y, 1,096G, 1,097A, 1,098S, 1,099Q, 1,100L, 1,102L, 1,103E, 1,104R, 1,105L, 1,106M, 1,107L, 1,111A, 1,144P, 1,148K, 1,150L, 1,152Q, 1,153E, 1,155I, 1,157M, 1,158N, 1,159I, 1,160A, 1,162R, 1,164K
CDD
cd00653 (RNA_pol_B_RPB2)

1,152Q

RPB1 interaction site
500G, 502R, 503A, 504L, 506P, 509F, 514T, 691E, 709H, 710H, 711N, 713S, 776V, 777M, 778S, 779Y, 782Y, 784I, 785E, 786D, 941K, 943V, 945G, 967N, 969H, 972P, 975M, 980M, 984V, 1,001F, 1,028S, 1,036Q, 1,037A, 1,038Y, 1,040F, 1,053V, 1,056K, 1,057M, 1,058H, 1,060R, 1,061A, 1,082L, 1,083R, 1,084L, 1,088E, 1,090D, 1,091C, 1,093I, 1,095Y, 1,096G, 1,097A, 1,098S, 1,099Q, 1,100L, 1,102L, 1,103E, 1,104R, 1,105L, 1,106M, 1,107L, 1,111A, 1,144P, 1,148K, 1,150L, 1,152Q, 1,153E, 1,155I, 1,157M, 1,158N, 1,159I, 1,160A, 1,162R, 1,164K
CDD
cd00653 (RNA_pol_B_RPB2)

1,153E

RPB1 interaction site
500G, 502R, 503A, 504L, 506P, 509F, 514T, 691E, 709H, 710H, 711N, 713S, 776V, 777M, 778S, 779Y, 782Y, 784I, 785E, 786D, 941K, 943V, 945G, 967N, 969H, 972P, 975M, 980M, 984V, 1,001F, 1,028S, 1,036Q, 1,037A, 1,038Y, 1,040F, 1,053V, 1,056K, 1,057M, 1,058H, 1,060R, 1,061A, 1,082L, 1,083R, 1,084L, 1,088E, 1,090D, 1,091C, 1,093I, 1,095Y, 1,096G, 1,097A, 1,098S, 1,099Q, 1,100L, 1,102L, 1,103E, 1,104R, 1,105L, 1,106M, 1,107L, 1,111A, 1,144P, 1,148K, 1,150L, 1,152Q, 1,153E, 1,155I, 1,157M, 1,158N, 1,159I, 1,160A, 1,162R, 1,164K
CDD
cd00653 (RNA_pol_B_RPB2)

1,155I

RPB1 interaction site
500G, 502R, 503A, 504L, 506P, 509F, 514T, 691E, 709H, 710H, 711N, 713S, 776V, 777M, 778S, 779Y, 782Y, 784I, 785E, 786D, 941K, 943V, 945G, 967N, 969H, 972P, 975M, 980M, 984V, 1,001F, 1,028S, 1,036Q, 1,037A, 1,038Y, 1,040F, 1,053V, 1,056K, 1,057M, 1,058H, 1,060R, 1,061A, 1,082L, 1,083R, 1,084L, 1,088E, 1,090D, 1,091C, 1,093I, 1,095Y, 1,096G, 1,097A, 1,098S, 1,099Q, 1,100L, 1,102L, 1,103E, 1,104R, 1,105L, 1,106M, 1,107L, 1,111A, 1,144P, 1,148K, 1,150L, 1,152Q, 1,153E, 1,155I, 1,157M, 1,158N, 1,159I, 1,160A, 1,162R, 1,164K
CDD
cd00653 (RNA_pol_B_RPB2)

1,157M

RPB1 interaction site
500G, 502R, 503A, 504L, 506P, 509F, 514T, 691E, 709H, 710H, 711N, 713S, 776V, 777M, 778S, 779Y, 782Y, 784I, 785E, 786D, 941K, 943V, 945G, 967N, 969H, 972P, 975M, 980M, 984V, 1,001F, 1,028S, 1,036Q, 1,037A, 1,038Y, 1,040F, 1,053V, 1,056K, 1,057M, 1,058H, 1,060R, 1,061A, 1,082L, 1,083R, 1,084L, 1,088E, 1,090D, 1,091C, 1,093I, 1,095Y, 1,096G, 1,097A, 1,098S, 1,099Q, 1,100L, 1,102L, 1,103E, 1,104R, 1,105L, 1,106M, 1,107L, 1,111A, 1,144P, 1,148K, 1,150L, 1,152Q, 1,153E, 1,155I, 1,157M, 1,158N, 1,159I, 1,160A, 1,162R, 1,164K
CDD
cd00653 (RNA_pol_B_RPB2)

1,158N

RPB1 interaction site
500G, 502R, 503A, 504L, 506P, 509F, 514T, 691E, 709H, 710H, 711N, 713S, 776V, 777M, 778S, 779Y, 782Y, 784I, 785E, 786D, 941K, 943V, 945G, 967N, 969H, 972P, 975M, 980M, 984V, 1,001F, 1,028S, 1,036Q, 1,037A, 1,038Y, 1,040F, 1,053V, 1,056K, 1,057M, 1,058H, 1,060R, 1,061A, 1,082L, 1,083R, 1,084L, 1,088E, 1,090D, 1,091C, 1,093I, 1,095Y, 1,096G, 1,097A, 1,098S, 1,099Q, 1,100L, 1,102L, 1,103E, 1,104R, 1,105L, 1,106M, 1,107L, 1,111A, 1,144P, 1,148K, 1,150L, 1,152Q, 1,153E, 1,155I, 1,157M, 1,158N, 1,159I, 1,160A, 1,162R, 1,164K
CDD
cd00653 (RNA_pol_B_RPB2)

1,159I

RPB1 interaction site
500G, 502R, 503A, 504L, 506P, 509F, 514T, 691E, 709H, 710H, 711N, 713S, 776V, 777M, 778S, 779Y, 782Y, 784I, 785E, 786D, 941K, 943V, 945G, 967N, 969H, 972P, 975M, 980M, 984V, 1,001F, 1,028S, 1,036Q, 1,037A, 1,038Y, 1,040F, 1,053V, 1,056K, 1,057M, 1,058H, 1,060R, 1,061A, 1,082L, 1,083R, 1,084L, 1,088E, 1,090D, 1,091C, 1,093I, 1,095Y, 1,096G, 1,097A, 1,098S, 1,099Q, 1,100L, 1,102L, 1,103E, 1,104R, 1,105L, 1,106M, 1,107L, 1,111A, 1,144P, 1,148K, 1,150L, 1,152Q, 1,153E, 1,155I, 1,157M, 1,158N, 1,159I, 1,160A, 1,162R, 1,164K
CDD
cd00653 (RNA_pol_B_RPB2)

1,160A

RPB1 interaction site
500G, 502R, 503A, 504L, 506P, 509F, 514T, 691E, 709H, 710H, 711N, 713S, 776V, 777M, 778S, 779Y, 782Y, 784I, 785E, 786D, 941K, 943V, 945G, 967N, 969H, 972P, 975M, 980M, 984V, 1,001F, 1,028S, 1,036Q, 1,037A, 1,038Y, 1,040F, 1,053V, 1,056K, 1,057M, 1,058H, 1,060R, 1,061A, 1,082L, 1,083R, 1,084L, 1,088E, 1,090D, 1,091C, 1,093I, 1,095Y, 1,096G, 1,097A, 1,098S, 1,099Q, 1,100L, 1,102L, 1,103E, 1,104R, 1,105L, 1,106M, 1,107L, 1,111A, 1,144P, 1,148K, 1,150L, 1,152Q, 1,153E, 1,155I, 1,157M, 1,158N, 1,159I, 1,160A, 1,162R, 1,164K
CDD
cd00653 (RNA_pol_B_RPB2)

1,162R

RPB1 interaction site
500G, 502R, 503A, 504L, 506P, 509F, 514T, 691E, 709H, 710H, 711N, 713S, 776V, 777M, 778S, 779Y, 782Y, 784I, 785E, 786D, 941K, 943V, 945G, 967N, 969H, 972P, 975M, 980M, 984V, 1,001F, 1,028S, 1,036Q, 1,037A, 1,038Y, 1,040F, 1,053V, 1,056K, 1,057M, 1,058H, 1,060R, 1,061A, 1,082L, 1,083R, 1,084L, 1,088E, 1,090D, 1,091C, 1,093I, 1,095Y, 1,096G, 1,097A, 1,098S, 1,099Q, 1,100L, 1,102L, 1,103E, 1,104R, 1,105L, 1,106M, 1,107L, 1,111A, 1,144P, 1,148K, 1,150L, 1,152Q, 1,153E, 1,155I, 1,157M, 1,158N, 1,159I, 1,160A, 1,162R, 1,164K
CDD
cd00653 (RNA_pol_B_RPB2)

1,164K

RPB1 interaction site
500G, 502R, 503A, 504L, 506P, 509F, 514T, 691E, 709H, 710H, 711N, 713S, 776V, 777M, 778S, 779Y, 782Y, 784I, 785E, 786D, 941K, 943V, 945G, 967N, 969H, 972P, 975M, 980M, 984V, 1,001F, 1,028S, 1,036Q, 1,037A, 1,038Y, 1,040F, 1,053V, 1,056K, 1,057M, 1,058H, 1,060R, 1,061A, 1,082L, 1,083R, 1,084L, 1,088E, 1,090D, 1,091C, 1,093I, 1,095Y, 1,096G, 1,097A, 1,098S, 1,099Q, 1,100L, 1,102L, 1,103E, 1,104R, 1,105L, 1,106M, 1,107L, 1,111A, 1,144P, 1,148K, 1,150L, 1,152Q, 1,153E, 1,155I, 1,157M, 1,158N, 1,159I, 1,160A, 1,162R, 1,164K
CDD
cd00653 (RNA_pol_B_RPB2)
RPB10 interaction ...

749Q

RPB10 interaction site
749Q, 750Q, 771N, 773V, 794S, 797R, 950Q, 963D, 990V, 991L, 993G, 1,024D, 1,041F
CDD
cd00653 (RNA_pol_B_RPB2)

750Q

RPB10 interaction site
749Q, 750Q, 771N, 773V, 794S, 797R, 950Q, 963D, 990V, 991L, 993G, 1,024D, 1,041F
CDD
cd00653 (RNA_pol_B_RPB2)

771N

RPB10 interaction site
749Q, 750Q, 771N, 773V, 794S, 797R, 950Q, 963D, 990V, 991L, 993G, 1,024D, 1,041F
CDD
cd00653 (RNA_pol_B_RPB2)

773V

RPB10 interaction site
749Q, 750Q, 771N, 773V, 794S, 797R, 950Q, 963D, 990V, 991L, 993G, 1,024D, 1,041F
CDD
cd00653 (RNA_pol_B_RPB2)

794S

RPB10 interaction site
749Q, 750Q, 771N, 773V, 794S, 797R, 950Q, 963D, 990V, 991L, 993G, 1,024D, 1,041F
CDD
cd00653 (RNA_pol_B_RPB2)

797R

RPB10 interaction site
749Q, 750Q, 771N, 773V, 794S, 797R, 950Q, 963D, 990V, 991L, 993G, 1,024D, 1,041F
CDD
cd00653 (RNA_pol_B_RPB2)

950Q

RPB10 interaction site
749Q, 750Q, 771N, 773V, 794S, 797R, 950Q, 963D, 990V, 991L, 993G, 1,024D, 1,041F
CDD
cd00653 (RNA_pol_B_RPB2)

963D

RPB10 interaction site
749Q, 750Q, 771N, 773V, 794S, 797R, 950Q, 963D, 990V, 991L, 993G, 1,024D, 1,041F
CDD
cd00653 (RNA_pol_B_RPB2)

990V

RPB10 interaction site
749Q, 750Q, 771N, 773V, 794S, 797R, 950Q, 963D, 990V, 991L, 993G, 1,024D, 1,041F
CDD
cd00653 (RNA_pol_B_RPB2)

991L

RPB10 interaction site
749Q, 750Q, 771N, 773V, 794S, 797R, 950Q, 963D, 990V, 991L, 993G, 1,024D, 1,041F
CDD
cd00653 (RNA_pol_B_RPB2)

993G

RPB10 interaction site
749Q, 750Q, 771N, 773V, 794S, 797R, 950Q, 963D, 990V, 991L, 993G, 1,024D, 1,041F
CDD
cd00653 (RNA_pol_B_RPB2)

1,024D

RPB10 interaction site
749Q, 750Q, 771N, 773V, 794S, 797R, 950Q, 963D, 990V, 991L, 993G, 1,024D, 1,041F
CDD
cd00653 (RNA_pol_B_RPB2)

1,041F

RPB10 interaction site
749Q, 750Q, 771N, 773V, 794S, 797R, 950Q, 963D, 990V, 991L, 993G, 1,024D, 1,041F
CDD
cd00653 (RNA_pol_B_RPB2)
RPB11 interaction ...

782Y

RPB11 interaction site
782Y, 796D, 949Q, 1,030I
CDD
cd00653 (RNA_pol_B_RPB2)

796D

RPB11 interaction site
782Y, 796D, 949Q, 1,030I
CDD
cd00653 (RNA_pol_B_RPB2)

949Q

RPB11 interaction site
782Y, 796D, 949Q, 1,030I
CDD
cd00653 (RNA_pol_B_RPB2)

1,030I

RPB11 interaction site
782Y, 796D, 949Q, 1,030I
CDD
cd00653 (RNA_pol_B_RPB2)
RPB3 interaction s...

796D

RPB3 interaction site
796D, 797R, 801R, 923R, 925T, 950Q, 951E, 952D, 955F, 957D, 958Q, 1,029G, 1,030I, 1,031T, 1,032G, 1,033E, 1,034C, 1,035L, 1,036Q, 1,038Y
CDD
cd00653 (RNA_pol_B_RPB2)

797R

RPB3 interaction site
796D, 797R, 801R, 923R, 925T, 950Q, 951E, 952D, 955F, 957D, 958Q, 1,029G, 1,030I, 1,031T, 1,032G, 1,033E, 1,034C, 1,035L, 1,036Q, 1,038Y
CDD
cd00653 (RNA_pol_B_RPB2)

801R

RPB3 interaction site
796D, 797R, 801R, 923R, 925T, 950Q, 951E, 952D, 955F, 957D, 958Q, 1,029G, 1,030I, 1,031T, 1,032G, 1,033E, 1,034C, 1,035L, 1,036Q, 1,038Y
CDD
cd00653 (RNA_pol_B_RPB2)

923R

RPB3 interaction site
796D, 797R, 801R, 923R, 925T, 950Q, 951E, 952D, 955F, 957D, 958Q, 1,029G, 1,030I, 1,031T, 1,032G, 1,033E, 1,034C, 1,035L, 1,036Q, 1,038Y
CDD
cd00653 (RNA_pol_B_RPB2)

925T

RPB3 interaction site
796D, 797R, 801R, 923R, 925T, 950Q, 951E, 952D, 955F, 957D, 958Q, 1,029G, 1,030I, 1,031T, 1,032G, 1,033E, 1,034C, 1,035L, 1,036Q, 1,038Y
CDD
cd00653 (RNA_pol_B_RPB2)

950Q

RPB3 interaction site
796D, 797R, 801R, 923R, 925T, 950Q, 951E, 952D, 955F, 957D, 958Q, 1,029G, 1,030I, 1,031T, 1,032G, 1,033E, 1,034C, 1,035L, 1,036Q, 1,038Y
CDD
cd00653 (RNA_pol_B_RPB2)

951E

RPB3 interaction site
796D, 797R, 801R, 923R, 925T, 950Q, 951E, 952D, 955F, 957D, 958Q, 1,029G, 1,030I, 1,031T, 1,032G, 1,033E, 1,034C, 1,035L, 1,036Q, 1,038Y
CDD
cd00653 (RNA_pol_B_RPB2)

952D

RPB3 interaction site
796D, 797R, 801R, 923R, 925T, 950Q, 951E, 952D, 955F, 957D, 958Q, 1,029G, 1,030I, 1,031T, 1,032G, 1,033E, 1,034C, 1,035L, 1,036Q, 1,038Y
CDD
cd00653 (RNA_pol_B_RPB2)

955F

RPB3 interaction site
796D, 797R, 801R, 923R, 925T, 950Q, 951E, 952D, 955F, 957D, 958Q, 1,029G, 1,030I, 1,031T, 1,032G, 1,033E, 1,034C, 1,035L, 1,036Q, 1,038Y
CDD
cd00653 (RNA_pol_B_RPB2)

957D

RPB3 interaction site
796D, 797R, 801R, 923R, 925T, 950Q, 951E, 952D, 955F, 957D, 958Q, 1,029G, 1,030I, 1,031T, 1,032G, 1,033E, 1,034C, 1,035L, 1,036Q, 1,038Y
CDD
cd00653 (RNA_pol_B_RPB2)

958Q

RPB3 interaction site
796D, 797R, 801R, 923R, 925T, 950Q, 951E, 952D, 955F, 957D, 958Q, 1,029G, 1,030I, 1,031T, 1,032G, 1,033E, 1,034C, 1,035L, 1,036Q, 1,038Y
CDD
cd00653 (RNA_pol_B_RPB2)

1,029G

RPB3 interaction site
796D, 797R, 801R, 923R, 925T, 950Q, 951E, 952D, 955F, 957D, 958Q, 1,029G, 1,030I, 1,031T, 1,032G, 1,033E, 1,034C, 1,035L, 1,036Q, 1,038Y
CDD
cd00653 (RNA_pol_B_RPB2)

1,030I

RPB3 interaction site
796D, 797R, 801R, 923R, 925T, 950Q, 951E, 952D, 955F, 957D, 958Q, 1,029G, 1,030I, 1,031T, 1,032G, 1,033E, 1,034C, 1,035L, 1,036Q, 1,038Y
CDD
cd00653 (RNA_pol_B_RPB2)

1,031T

RPB3 interaction site
796D, 797R, 801R, 923R, 925T, 950Q, 951E, 952D, 955F, 957D, 958Q, 1,029G, 1,030I, 1,031T, 1,032G, 1,033E, 1,034C, 1,035L, 1,036Q, 1,038Y
CDD
cd00653 (RNA_pol_B_RPB2)

1,032G

RPB3 interaction site
796D, 797R, 801R, 923R, 925T, 950Q, 951E, 952D, 955F, 957D, 958Q, 1,029G, 1,030I, 1,031T, 1,032G, 1,033E, 1,034C, 1,035L, 1,036Q, 1,038Y
CDD
cd00653 (RNA_pol_B_RPB2)

1,033E

RPB3 interaction site
796D, 797R, 801R, 923R, 925T, 950Q, 951E, 952D, 955F, 957D, 958Q, 1,029G, 1,030I, 1,031T, 1,032G, 1,033E, 1,034C, 1,035L, 1,036Q, 1,038Y
CDD
cd00653 (RNA_pol_B_RPB2)

1,034C

RPB3 interaction site
796D, 797R, 801R, 923R, 925T, 950Q, 951E, 952D, 955F, 957D, 958Q, 1,029G, 1,030I, 1,031T, 1,032G, 1,033E, 1,034C, 1,035L, 1,036Q, 1,038Y
CDD
cd00653 (RNA_pol_B_RPB2)

1,035L

RPB3 interaction site
796D, 797R, 801R, 923R, 925T, 950Q, 951E, 952D, 955F, 957D, 958Q, 1,029G, 1,030I, 1,031T, 1,032G, 1,033E, 1,034C, 1,035L, 1,036Q, 1,038Y
CDD
cd00653 (RNA_pol_B_RPB2)

1,036Q

RPB3 interaction site
796D, 797R, 801R, 923R, 925T, 950Q, 951E, 952D, 955F, 957D, 958Q, 1,029G, 1,030I, 1,031T, 1,032G, 1,033E, 1,034C, 1,035L, 1,036Q, 1,038Y
CDD
cd00653 (RNA_pol_B_RPB2)

1,038Y

RPB3 interaction site
796D, 797R, 801R, 923R, 925T, 950Q, 951E, 952D, 955F, 957D, 958Q, 1,029G, 1,030I, 1,031T, 1,032G, 1,033E, 1,034C, 1,035L, 1,036Q, 1,038Y
CDD
cd00653 (RNA_pol_B_RPB2)

Protein sequence

>MIA_00494_1
MPISKTDHKQSHDHDHDHDHDLSTAGTDQAFNQLLQPMYMGKELTDKIDTARDKWNLLPAFLKVKGLVKQHLDSFNYFVD
VDIKKIIKANEKVVSDVDPQFYLVYKDIRVGRPQRQEEAARDDIFTPHECRLRDLTYAAPIFVDVEYTRGNKIIINRGLE
LARMPIMLRSSKCVLFEKDEMQMADMKECPLDPGGYFIVNGTEKVILIQEQLSKNRIIVEADEKKGIVQASVTSSTHERK
SKTYVLTKNDKIYLKHNSISEDVPIVIMLKAAGIVSDQEILQLVCGSNPKYQDLFAINFEEATRYGVYTQHQALEYLGTK
IRTVRRASSQKLTPIQEGIEAIATTIIAHINVDGLDFREKAVYMAIMTRRVVQTMDNPKMVDDRDYVGNKRLELAGQLMS
LLFEDLFKTLNSSFKELMDKTLRKRNLASEFDAVQHIVSHGRFITSGLNRAISTGNWSLKRFKMERAGVTHVLSRLSYIS
ALGMMTRISSQFEKSRKVSGPRALQPSQFGMLCTSDTPEGEACGLVKNLALMTHITTDDDEEPIKKLSFVLGAEDISVIG
GLELHLPGVYGIYINGTIIGVTRFPLKFISNFRYMRRRGKVSEFISIYCNHHHNAVHIATDGGRICRPLIIVENKKSKVT
AEHLYKLRTGQMVFDDFLRLGIVEYLDCNEENDSYIAIYEKDIIYETTHLEIEPFTVLGAVAGLIPYPHHNQSPRNTYQC
AMGKQAIGSIAYNQLNRIDTLLYFMVYPQQPMVKSRTIELINYDKLPAGQNAVVAVMSYSGYDIEDALVINKGSLDRGFG
RCQVMKKNTTVLRRYARVADRLNGINYEQVHKNQTPVPIPQHSELDVDGLVQVGVKVESGKVYINKAVPIDTGDNPTAVI
NGSTTTEYRETPVVYKGPEGSYIDKVMLSSSESEEPIIKVLLRQTRRPELGDKFSSRHGQKGVCGIIVQQEDMPFNDQGI
NPDIIMNPHGFPSRMTVGKMIELVSGKAGVLDGSLQYGTCFGGSKLEDMSRILVEKGFNYSGKDMLYSGITGECLQAYIF
FGPIYYQKLKHMVMDKMHARARGPRAVLTRQPTEGRSRDGGLRLGEMERDCVIAYGASQLLLERLMLSSDAFEVDVCQKC
GLMGYQGWCPTCQVTEGVVKMTIPYAAKLLFQELISMNIAPRLKLGEVF

GO term prediction

Biological Process

GO:0006351 transcription, DNA-templated

Molecular Function

GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0032549 ribonucleoside binding

Cellular Component

None predicted.

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Entry type

Status

Per-residue features