Protein

MIA_00492_1

Length
195 amino acids

Browser: contig01:1421606-1422194+

Protein function

EGGNOG:0PJ5TTSA1Peroxiredoxin
SGD closest match:S000004490TSA1Peroxiredoxin TSA1
CGD closest match:CAL0000174369TSA1Peroxiredoxin TSA1-A

Protein alignments

%idAln lengthE-value
MCA_05369_187.435%1913.45e-127MCA_05369_1
A0A0J9XF13_GEOCN84.615%1951.50e-126Similar to Saccharomyces cerevisiae YML028W TSA1 Thioredoxin peroxidase OS=Geotrichum candidum GN=BN980_GECA12s04025g PE=4 SV=1
Q6CEJ7_YARLI82.051%1957.36e-121YALI0B15125p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B15125g PE=4 SV=1
A0A060TI57_BLAAD80.513%1952.42e-118ARAD1D36322p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D36322g PE=4 SV=1
A0A1E3PH20_9ASCO75.897%1956.56e-114Thioredoxin-like protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_47432 PE=4 SV=1
UniRef50_A0A0L0P0E174.872%1959.54e-110Peroxiredoxin tsa1 n=7 Tax=Opisthokonta TaxID=33154 RepID=A0A0L0P0E1_9ASCO
A0A1E4TLC0_9ASCO73.196%1945.40e-112Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_30677 PE=4 SV=1
TSA1_CANAL72.821%1957.03e-112Peroxiredoxin TSA1-A OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=TSA1 PE=2 SV=1
A0A167E6Z8_9ASCO75.648%1932.57e-111Thioredoxin peroxidase TSA1 OS=Sugiyamaella lignohabitans GN=TSA1 PE=4 SV=1
TSA1_YEAST72.821%1955.26e-104Peroxiredoxin TSA1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TSA1 PE=1 SV=3

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.4400

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 20 40 60 80 100 120 140 160 180 195

Detailed signature matches

  1. Family IPR024706
    Peroxiredoxin, AhpC-type
    1. PIRSF000239 (AHPC)
  2. Domain IPR012336
    Thioredoxin-like fold
    1. SSF52833 (Thioredox...)
  3. Domain IPR013766
    Thioredoxin domain
    1. PS51352 (THIOREDOXIN_2)
  4. Domain IPR000866
    Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant
    1. PF00578 (AhpC-TSA)
  5. Domain IPR019479
    Peroxiredoxin, C-terminal
    1. PF10417 (1-cysPrx_C)
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. G3DSA:3.30.10...
  3. G3DSA:3.40.30.10
  4. NON_CYTOPLASM... (N...)
  5. SFLDS00024 (Peroxir...)
  6. TMhelix
  7. TRANSMEMBRANE (Tran...)
  8. cd03015 (PRX_Typ2cys)

Residue annotation

  1. dimer interface cd...
  2. decamer (pentamer ...
  3. SFLDS00024
  4. catalytic triad cd...
  5. peroxidatic and re...

Protein sequence

>MIA_00492_1
MVATVRHPAPAFKKTAVVNGLFEEVSLEQYKGKWVVLGFFPLAFTFVCPTEIIAFSEAAAQFKERNAEVLLASTDSEYSL
LAWTNVARKEGGLGQIDIPLVADTNHTLSRDYGVLIEEDGVALRGLFIIDPKGTVRQITINDLPVGRSVDETLRLIDAFQ
FTEEHGEVCPANWHKGDATLIADPVKSKEYFSKAN

GO term prediction

Biological Process

GO:0045454 cell redox homeostasis
GO:0055114 oxidation-reduction process

Molecular Function

GO:0016209 antioxidant activity
GO:0016491 oxidoreductase activity
GO:0051920 peroxiredoxin activity

Cellular Component

None predicted.