Protein

MIA_00456_1

Length
460 amino acids


Browser: contig01:1302692-1304130-

Protein function

EGGNOG:0PFDUTUB4Tubulin is the major constituent of microtubules. Gamma tubulin is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome (By similarity)
SGD closest match:S000001857TUB2Tubulin beta chain
CGD closest match:CAL0000176403TUB2Tubulin beta chain

Protein alignments

%idAln lengthE-value
A0A0J9X9R4_GEOCN82.495%4570.0Tubulin gamma chain OS=Geotrichum candidum GN=BN980_GECA06s01748g PE=3 SV=1
MCA_01339_180.176%4540.0MCA_01339_1
A0A060T8B6_BLAAD76.458%4630.0Tubulin gamma chain OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C28072g PE=3 SV=1
UniRef50_M1VVG467.841%4540.0Probable tubulin gamma chain n=1 Tax=Claviceps purpurea (strain 20.1) TaxID=1111077 RepID=M1VVG4_CLAP2
Q6CFF9_YARLI68.683%4630.0Tubulin gamma chain OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B07381g PE=3 SV=1
A0A1E4TLU8_9ASCO62.017%4660.0Tubulin gamma chain OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_1330 PE=3 SV=1
A0A167FNJ2_9ASCO78.804%3680.0Tubulin gamma chain OS=Sugiyamaella lignohabitans GN=TUB4 PE=3 SV=1
A0A1E3PLW6_9ASCO66.024%4152.98e-161Tubulin gamma chain OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_45893 PE=3 SV=1
A0A1D8PC97_CANAL33.407%4524.68e-80Tubulin beta chain OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=TUB2 PE=3 SV=1
TBB_YEAST32.743%4521.89e-78Tubulin beta chain OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TUB2 PE=1 SV=2

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0920

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
  3. Domain
1 50 100 150 200 250 300 350 400 460

Detailed signature matches

    1. PR01161 (TUBULIN)
    1. cd02188 (gamma_tubulin)
    2. PR01164 (GAMMATUBULIN)
    1. PF00091 (Tubulin)
    2. SM00864 (Tubulin_4)
    3. SSF52490 (Tubulin n...)
    1. SSF55307 (Tubulin C...)
    1. PF03953 (Tubulin_C)
    2. SM00865 (Tubulin_C_4)
    1. PS00227 (TUBULIN)
Unintegrated signatures no IPR
Unintegrated signatures

Residue annotation

  1. oligomer interface...
  2. nucleotide binding...

Protein sequence

>MIA_00456_1
MPRELITIQAGQCGNQIGSQFWQQLCLEHGISPDGTLQPYANTAIAGDRKDVFFYQSDDTRYIPRALLIDLEPRVINSIM
AGSHARMFNPENIFVSPNGGGAGNIWAAGYHAGEQISDSLMDMLDREAEGSDSLEGFMLLHSIAGGTGSGLGSFLLEHIN
DRFPKKLIQTYSVFPDSQQVSDVVVQPYNSVLTLKRLALYADSVIVLDNGALARIAAETLKVQSPTFDQTNQLVSTVMSA
STSTLRYPGYLHNDLASILASLIPLPRCHFLMTAYTPFSNETVDQAKLVRKTTVLDVMRRLLQPKNRMVSTGQSKAACYL
SILNIIQGDVDPTDIHKALLRIRERNLANFIPSAPTSIQISLSRRSPYLYRNNNTNSESATIDPSTRISGLMLANHTAIS
SLFNRTVDQFDRLLKRQAFLEPYRRQPMFENGLAEFEDAREHVMDVIKEYKRLEPPITTM

GO term prediction

Biological Process

GO:0007017 microtubule-based process
GO:0007020 microtubule nucleation
GO:0031122 cytoplasmic microtubule organization

Molecular Function

GO:0003924 GTPase activity
GO:0005525 GTP binding

Cellular Component

GO:0000930 gamma-tubulin complex
GO:0005874 microtubule