MIA_00439_1

Protein

Length

1,172 amino acids

Protein function

EGGNOG:	0PFMF	FG05627.1	dna-directed rna polymerase
SGD closest match:	S000006214	RPA135	DNA-directed RNA polymerase I subunit RPA135
CGD closest match:	CAL0000201405	RPA135	DNA-directed RNA polymerase subunit beta

Protein alignments

	%id	Aln length
MCA_05971_1	83.234%	1169	MCA_05971_1
A0A0J9XCF1_GEOCN	76.581%	1170	DNA-directed RNA polymerase subunit beta OS=Geotrichum candidum GN=BN980_GECA09s01055g PE=3 SV=1
A0A1E3PPM7_9ASCO	74.915%	1172	DNA-directed RNA polymerase subunit beta OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_50775 PE=3 SV=1
A0A060TIY2_BLAAD	75.021%	1169	DNA-directed RNA polymerase subunit beta OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D42196g PE=3 SV=1
A0A1D8PQM4_CANAL	73.653%	1169	DNA-directed RNA polymerase subunit beta OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=RPA135 PE=3 SV=1
RPA2_YEAST	70.243%	1193	DNA-directed RNA polymerase I subunit RPA135 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RPA135 PE=1 SV=1
UniRef50_P22138	70.243%	1193	DNA-directed RNA polymerase I subunit RPA135 n=399 Tax=Opisthokonta TaxID=33154 RepID=RPA2_YEAST
A0A161HI57_9ASCO	76.746%	1045	DNA-directed RNA polymerase subunit beta OS=Sugiyamaella lignohabitans GN=RPA135 PE=3 SV=1
Q6C6G0_YARLI	68.895%	1167	DNA-directed RNA polymerase subunit beta OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E09845g PE=3 SV=1
A0A1E4TIB9_9ASCO	65.612%	1169	DNA-directed RNA polymerase subunit beta OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_71761 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0284

Protein family membership

DNA-directed RNA polymerase, subunit 2 (IPR015712)

Domains and repeats

Domain
31 - 412
RNA polymerase, beta subunit, protrusion (IPR007644)
Domain
189 - 378
RNA polymerase Rpb2, domain 2 (IPR007642)
463 - 527
RNA polymerase Rpb2, domain 3 (IPR007645)
568 - 627
DNA-directed RNA polymerase I subunit RPA2, domain 4 (IPR009674)
675 - 1,039
DNA-directed RNA polymerase, subunit 2, domain 6 (IPR007120)
1,041 - 1,165
RNA polymerase Rpb2, domain 7 (IPR007641)

1 200 400 600 800 1000 1172

Detailed signature matches

IPR015712

DNA-directed RNA polymerase, subunit 2
1. cd00653 (RNA_pol_B_...)
  
  31 - 1,164
  
  CDD
  cd00653 (RNA_pol_B_RPB2)
IPR007644

RNA polymerase, beta subunit, protrusion
1. PF04563 (RNA_pol_Rp...)
  
  31 - 412
  
  Pfam
  PF04563 (RNA_pol_Rpb2_1)
IPR007642

RNA polymerase Rpb2, domain 2
1. PF04561 (RNA_pol_Rp...)
  
  189 - 378
  
  Pfam
  PF04561 (RNA_pol_Rpb2_2)
2. G3DSA:3.90.11...
  
  204 - 369
  
  GENE3D
  G3DSA:3.90.1110.10 (G3DSA:3.90.1110.10)
IPR007645

RNA polymerase Rpb2, domain 3
1. PF04565 (RNA_pol_Rp...)
  
  463 - 527
  
  Pfam
  PF04565 (RNA_pol_Rpb2_3)
IPR009674

DNA-directed RNA polymerase I subunit RPA2, domain 4
1. PF06883 (RNA_pol_Rp...)
  
  568 - 627
  
  Pfam
  PF06883 (RNA_pol_Rpa2_4)
IPR007120

DNA-directed RNA polymerase, subunit 2, domain 6
1. G3DSA:2.40.27...
  
  675 - 1,025
  
  GENE3D
  G3DSA:2.40.270.10 (G3DSA:2.40.270.10)
2. PF00562 (RNA_pol_Rp...)
  
  676 - 1,039
  
  Pfam
  PF00562 (RNA_pol_Rpb2_6)
IPR007641

RNA polymerase Rpb2, domain 7
1. PF04560 (RNA_pol_Rp...)
  
  1,041 - 1,165
  
  Pfam
  PF04560 (RNA_pol_Rpb2_7)
IPR007121

RNA polymerase, beta subunit, conserved site
1. PS01166 (RNA_POL_BETA)
  
  888 - 900
  
  PROSITE patterns
  PS01166 (RNA_POL_BETA)

no IPR

Unintegrated signatures

G3DSA:3.90.11...

24 - 203

GENE3D
G3DSA:3.90.1100.10 (G3DSA:3.90.1100.10)
G3DSA:3.90.18...

1,042 - 1,159

GENE3D
G3DSA:3.90.1800.10 (G3DSA:3.90.1800.10)
SSF64484 (beta and ...)

1,135 - 1,166

SUPERFAMILY
SSF64484 (beta and beta-prime subunits of DNA dependent RNA-polymerase)

10 - 1,106

SUPERFAMILY
SSF64484 (beta and beta-prime subunits of DNA dependent RNA-polymerase)

Residue annotation

RPB12 interaction ...

109R

RPB12 interaction site
109R, 776H, 817D, 819D, 823M, 824I, 825G, 827M
CDD
cd00653 (RNA_pol_B_RPB2)

776H

RPB12 interaction site
109R, 776H, 817D, 819D, 823M, 824I, 825G, 827M
CDD
cd00653 (RNA_pol_B_RPB2)

817D

RPB12 interaction site
109R, 776H, 817D, 819D, 823M, 824I, 825G, 827M
CDD
cd00653 (RNA_pol_B_RPB2)

819D

RPB12 interaction site
109R, 776H, 817D, 819D, 823M, 824I, 825G, 827M
CDD
cd00653 (RNA_pol_B_RPB2)

823M

RPB12 interaction site
109R, 776H, 817D, 819D, 823M, 824I, 825G, 827M
CDD
cd00653 (RNA_pol_B_RPB2)

824I

RPB12 interaction site
109R, 776H, 817D, 819D, 823M, 824I, 825G, 827M
CDD
cd00653 (RNA_pol_B_RPB2)

825G

RPB12 interaction site
109R, 776H, 817D, 819D, 823M, 824I, 825G, 827M
CDD
cd00653 (RNA_pol_B_RPB2)

827M

RPB12 interaction site
109R, 776H, 817D, 819D, 823M, 824I, 825G, 827M
CDD
cd00653 (RNA_pol_B_RPB2)
RPB1 interaction s...

492T

RPB1 interaction site
492T, 494R, 495K, 496L, 498P, 501W, 506P, 666E, 684D, 685F, 686N, 688S, 751V, 752I, 753S, 754Y, 757Y, 759M, 760D, 761D, 898K, 900V, 902S, 924N, 926H, 929P, 932M, 937F, 941L, 958W, 989S, 997R, 998V, 999D, 1,001Y, 1,014V, 1,017K, 1,018F, 1,019Q, 1,021R, 1,022S, 1,043I, 1,044R, 1,045V, 1,049E, 1,051D, 1,052A, 1,054I, 1,056H, 1,057G, 1,058T, 1,059A, 1,060Y, 1,061L, 1,063Q, 1,064D, 1,065R, 1,066L, 1,067L, 1,068N, 1,072Y, 1,145P, 1,149K, 1,151L, 1,153S, 1,154E, 1,156A, 1,158M, 1,159G, 1,160I, 1,161K, 1,163R
CDD
cd00653 (RNA_pol_B_RPB2)

494R

RPB1 interaction site
492T, 494R, 495K, 496L, 498P, 501W, 506P, 666E, 684D, 685F, 686N, 688S, 751V, 752I, 753S, 754Y, 757Y, 759M, 760D, 761D, 898K, 900V, 902S, 924N, 926H, 929P, 932M, 937F, 941L, 958W, 989S, 997R, 998V, 999D, 1,001Y, 1,014V, 1,017K, 1,018F, 1,019Q, 1,021R, 1,022S, 1,043I, 1,044R, 1,045V, 1,049E, 1,051D, 1,052A, 1,054I, 1,056H, 1,057G, 1,058T, 1,059A, 1,060Y, 1,061L, 1,063Q, 1,064D, 1,065R, 1,066L, 1,067L, 1,068N, 1,072Y, 1,145P, 1,149K, 1,151L, 1,153S, 1,154E, 1,156A, 1,158M, 1,159G, 1,160I, 1,161K, 1,163R
CDD
cd00653 (RNA_pol_B_RPB2)

495K

RPB1 interaction site
492T, 494R, 495K, 496L, 498P, 501W, 506P, 666E, 684D, 685F, 686N, 688S, 751V, 752I, 753S, 754Y, 757Y, 759M, 760D, 761D, 898K, 900V, 902S, 924N, 926H, 929P, 932M, 937F, 941L, 958W, 989S, 997R, 998V, 999D, 1,001Y, 1,014V, 1,017K, 1,018F, 1,019Q, 1,021R, 1,022S, 1,043I, 1,044R, 1,045V, 1,049E, 1,051D, 1,052A, 1,054I, 1,056H, 1,057G, 1,058T, 1,059A, 1,060Y, 1,061L, 1,063Q, 1,064D, 1,065R, 1,066L, 1,067L, 1,068N, 1,072Y, 1,145P, 1,149K, 1,151L, 1,153S, 1,154E, 1,156A, 1,158M, 1,159G, 1,160I, 1,161K, 1,163R
CDD
cd00653 (RNA_pol_B_RPB2)

496L

RPB1 interaction site
492T, 494R, 495K, 496L, 498P, 501W, 506P, 666E, 684D, 685F, 686N, 688S, 751V, 752I, 753S, 754Y, 757Y, 759M, 760D, 761D, 898K, 900V, 902S, 924N, 926H, 929P, 932M, 937F, 941L, 958W, 989S, 997R, 998V, 999D, 1,001Y, 1,014V, 1,017K, 1,018F, 1,019Q, 1,021R, 1,022S, 1,043I, 1,044R, 1,045V, 1,049E, 1,051D, 1,052A, 1,054I, 1,056H, 1,057G, 1,058T, 1,059A, 1,060Y, 1,061L, 1,063Q, 1,064D, 1,065R, 1,066L, 1,067L, 1,068N, 1,072Y, 1,145P, 1,149K, 1,151L, 1,153S, 1,154E, 1,156A, 1,158M, 1,159G, 1,160I, 1,161K, 1,163R
CDD
cd00653 (RNA_pol_B_RPB2)

498P

RPB1 interaction site
492T, 494R, 495K, 496L, 498P, 501W, 506P, 666E, 684D, 685F, 686N, 688S, 751V, 752I, 753S, 754Y, 757Y, 759M, 760D, 761D, 898K, 900V, 902S, 924N, 926H, 929P, 932M, 937F, 941L, 958W, 989S, 997R, 998V, 999D, 1,001Y, 1,014V, 1,017K, 1,018F, 1,019Q, 1,021R, 1,022S, 1,043I, 1,044R, 1,045V, 1,049E, 1,051D, 1,052A, 1,054I, 1,056H, 1,057G, 1,058T, 1,059A, 1,060Y, 1,061L, 1,063Q, 1,064D, 1,065R, 1,066L, 1,067L, 1,068N, 1,072Y, 1,145P, 1,149K, 1,151L, 1,153S, 1,154E, 1,156A, 1,158M, 1,159G, 1,160I, 1,161K, 1,163R
CDD
cd00653 (RNA_pol_B_RPB2)

501W

RPB1 interaction site
492T, 494R, 495K, 496L, 498P, 501W, 506P, 666E, 684D, 685F, 686N, 688S, 751V, 752I, 753S, 754Y, 757Y, 759M, 760D, 761D, 898K, 900V, 902S, 924N, 926H, 929P, 932M, 937F, 941L, 958W, 989S, 997R, 998V, 999D, 1,001Y, 1,014V, 1,017K, 1,018F, 1,019Q, 1,021R, 1,022S, 1,043I, 1,044R, 1,045V, 1,049E, 1,051D, 1,052A, 1,054I, 1,056H, 1,057G, 1,058T, 1,059A, 1,060Y, 1,061L, 1,063Q, 1,064D, 1,065R, 1,066L, 1,067L, 1,068N, 1,072Y, 1,145P, 1,149K, 1,151L, 1,153S, 1,154E, 1,156A, 1,158M, 1,159G, 1,160I, 1,161K, 1,163R
CDD
cd00653 (RNA_pol_B_RPB2)

506P

RPB1 interaction site
492T, 494R, 495K, 496L, 498P, 501W, 506P, 666E, 684D, 685F, 686N, 688S, 751V, 752I, 753S, 754Y, 757Y, 759M, 760D, 761D, 898K, 900V, 902S, 924N, 926H, 929P, 932M, 937F, 941L, 958W, 989S, 997R, 998V, 999D, 1,001Y, 1,014V, 1,017K, 1,018F, 1,019Q, 1,021R, 1,022S, 1,043I, 1,044R, 1,045V, 1,049E, 1,051D, 1,052A, 1,054I, 1,056H, 1,057G, 1,058T, 1,059A, 1,060Y, 1,061L, 1,063Q, 1,064D, 1,065R, 1,066L, 1,067L, 1,068N, 1,072Y, 1,145P, 1,149K, 1,151L, 1,153S, 1,154E, 1,156A, 1,158M, 1,159G, 1,160I, 1,161K, 1,163R
CDD
cd00653 (RNA_pol_B_RPB2)

666E

RPB1 interaction site
492T, 494R, 495K, 496L, 498P, 501W, 506P, 666E, 684D, 685F, 686N, 688S, 751V, 752I, 753S, 754Y, 757Y, 759M, 760D, 761D, 898K, 900V, 902S, 924N, 926H, 929P, 932M, 937F, 941L, 958W, 989S, 997R, 998V, 999D, 1,001Y, 1,014V, 1,017K, 1,018F, 1,019Q, 1,021R, 1,022S, 1,043I, 1,044R, 1,045V, 1,049E, 1,051D, 1,052A, 1,054I, 1,056H, 1,057G, 1,058T, 1,059A, 1,060Y, 1,061L, 1,063Q, 1,064D, 1,065R, 1,066L, 1,067L, 1,068N, 1,072Y, 1,145P, 1,149K, 1,151L, 1,153S, 1,154E, 1,156A, 1,158M, 1,159G, 1,160I, 1,161K, 1,163R
CDD
cd00653 (RNA_pol_B_RPB2)

684D

RPB1 interaction site
492T, 494R, 495K, 496L, 498P, 501W, 506P, 666E, 684D, 685F, 686N, 688S, 751V, 752I, 753S, 754Y, 757Y, 759M, 760D, 761D, 898K, 900V, 902S, 924N, 926H, 929P, 932M, 937F, 941L, 958W, 989S, 997R, 998V, 999D, 1,001Y, 1,014V, 1,017K, 1,018F, 1,019Q, 1,021R, 1,022S, 1,043I, 1,044R, 1,045V, 1,049E, 1,051D, 1,052A, 1,054I, 1,056H, 1,057G, 1,058T, 1,059A, 1,060Y, 1,061L, 1,063Q, 1,064D, 1,065R, 1,066L, 1,067L, 1,068N, 1,072Y, 1,145P, 1,149K, 1,151L, 1,153S, 1,154E, 1,156A, 1,158M, 1,159G, 1,160I, 1,161K, 1,163R
CDD
cd00653 (RNA_pol_B_RPB2)

685F

RPB1 interaction site
492T, 494R, 495K, 496L, 498P, 501W, 506P, 666E, 684D, 685F, 686N, 688S, 751V, 752I, 753S, 754Y, 757Y, 759M, 760D, 761D, 898K, 900V, 902S, 924N, 926H, 929P, 932M, 937F, 941L, 958W, 989S, 997R, 998V, 999D, 1,001Y, 1,014V, 1,017K, 1,018F, 1,019Q, 1,021R, 1,022S, 1,043I, 1,044R, 1,045V, 1,049E, 1,051D, 1,052A, 1,054I, 1,056H, 1,057G, 1,058T, 1,059A, 1,060Y, 1,061L, 1,063Q, 1,064D, 1,065R, 1,066L, 1,067L, 1,068N, 1,072Y, 1,145P, 1,149K, 1,151L, 1,153S, 1,154E, 1,156A, 1,158M, 1,159G, 1,160I, 1,161K, 1,163R
CDD
cd00653 (RNA_pol_B_RPB2)

686N

RPB1 interaction site
492T, 494R, 495K, 496L, 498P, 501W, 506P, 666E, 684D, 685F, 686N, 688S, 751V, 752I, 753S, 754Y, 757Y, 759M, 760D, 761D, 898K, 900V, 902S, 924N, 926H, 929P, 932M, 937F, 941L, 958W, 989S, 997R, 998V, 999D, 1,001Y, 1,014V, 1,017K, 1,018F, 1,019Q, 1,021R, 1,022S, 1,043I, 1,044R, 1,045V, 1,049E, 1,051D, 1,052A, 1,054I, 1,056H, 1,057G, 1,058T, 1,059A, 1,060Y, 1,061L, 1,063Q, 1,064D, 1,065R, 1,066L, 1,067L, 1,068N, 1,072Y, 1,145P, 1,149K, 1,151L, 1,153S, 1,154E, 1,156A, 1,158M, 1,159G, 1,160I, 1,161K, 1,163R
CDD
cd00653 (RNA_pol_B_RPB2)

688S

RPB1 interaction site
492T, 494R, 495K, 496L, 498P, 501W, 506P, 666E, 684D, 685F, 686N, 688S, 751V, 752I, 753S, 754Y, 757Y, 759M, 760D, 761D, 898K, 900V, 902S, 924N, 926H, 929P, 932M, 937F, 941L, 958W, 989S, 997R, 998V, 999D, 1,001Y, 1,014V, 1,017K, 1,018F, 1,019Q, 1,021R, 1,022S, 1,043I, 1,044R, 1,045V, 1,049E, 1,051D, 1,052A, 1,054I, 1,056H, 1,057G, 1,058T, 1,059A, 1,060Y, 1,061L, 1,063Q, 1,064D, 1,065R, 1,066L, 1,067L, 1,068N, 1,072Y, 1,145P, 1,149K, 1,151L, 1,153S, 1,154E, 1,156A, 1,158M, 1,159G, 1,160I, 1,161K, 1,163R
CDD
cd00653 (RNA_pol_B_RPB2)

751V

RPB1 interaction site
492T, 494R, 495K, 496L, 498P, 501W, 506P, 666E, 684D, 685F, 686N, 688S, 751V, 752I, 753S, 754Y, 757Y, 759M, 760D, 761D, 898K, 900V, 902S, 924N, 926H, 929P, 932M, 937F, 941L, 958W, 989S, 997R, 998V, 999D, 1,001Y, 1,014V, 1,017K, 1,018F, 1,019Q, 1,021R, 1,022S, 1,043I, 1,044R, 1,045V, 1,049E, 1,051D, 1,052A, 1,054I, 1,056H, 1,057G, 1,058T, 1,059A, 1,060Y, 1,061L, 1,063Q, 1,064D, 1,065R, 1,066L, 1,067L, 1,068N, 1,072Y, 1,145P, 1,149K, 1,151L, 1,153S, 1,154E, 1,156A, 1,158M, 1,159G, 1,160I, 1,161K, 1,163R
CDD
cd00653 (RNA_pol_B_RPB2)

752I

RPB1 interaction site
492T, 494R, 495K, 496L, 498P, 501W, 506P, 666E, 684D, 685F, 686N, 688S, 751V, 752I, 753S, 754Y, 757Y, 759M, 760D, 761D, 898K, 900V, 902S, 924N, 926H, 929P, 932M, 937F, 941L, 958W, 989S, 997R, 998V, 999D, 1,001Y, 1,014V, 1,017K, 1,018F, 1,019Q, 1,021R, 1,022S, 1,043I, 1,044R, 1,045V, 1,049E, 1,051D, 1,052A, 1,054I, 1,056H, 1,057G, 1,058T, 1,059A, 1,060Y, 1,061L, 1,063Q, 1,064D, 1,065R, 1,066L, 1,067L, 1,068N, 1,072Y, 1,145P, 1,149K, 1,151L, 1,153S, 1,154E, 1,156A, 1,158M, 1,159G, 1,160I, 1,161K, 1,163R
CDD
cd00653 (RNA_pol_B_RPB2)

753S

RPB1 interaction site
492T, 494R, 495K, 496L, 498P, 501W, 506P, 666E, 684D, 685F, 686N, 688S, 751V, 752I, 753S, 754Y, 757Y, 759M, 760D, 761D, 898K, 900V, 902S, 924N, 926H, 929P, 932M, 937F, 941L, 958W, 989S, 997R, 998V, 999D, 1,001Y, 1,014V, 1,017K, 1,018F, 1,019Q, 1,021R, 1,022S, 1,043I, 1,044R, 1,045V, 1,049E, 1,051D, 1,052A, 1,054I, 1,056H, 1,057G, 1,058T, 1,059A, 1,060Y, 1,061L, 1,063Q, 1,064D, 1,065R, 1,066L, 1,067L, 1,068N, 1,072Y, 1,145P, 1,149K, 1,151L, 1,153S, 1,154E, 1,156A, 1,158M, 1,159G, 1,160I, 1,161K, 1,163R
CDD
cd00653 (RNA_pol_B_RPB2)

754Y

RPB1 interaction site
492T, 494R, 495K, 496L, 498P, 501W, 506P, 666E, 684D, 685F, 686N, 688S, 751V, 752I, 753S, 754Y, 757Y, 759M, 760D, 761D, 898K, 900V, 902S, 924N, 926H, 929P, 932M, 937F, 941L, 958W, 989S, 997R, 998V, 999D, 1,001Y, 1,014V, 1,017K, 1,018F, 1,019Q, 1,021R, 1,022S, 1,043I, 1,044R, 1,045V, 1,049E, 1,051D, 1,052A, 1,054I, 1,056H, 1,057G, 1,058T, 1,059A, 1,060Y, 1,061L, 1,063Q, 1,064D, 1,065R, 1,066L, 1,067L, 1,068N, 1,072Y, 1,145P, 1,149K, 1,151L, 1,153S, 1,154E, 1,156A, 1,158M, 1,159G, 1,160I, 1,161K, 1,163R
CDD
cd00653 (RNA_pol_B_RPB2)

757Y

RPB1 interaction site
492T, 494R, 495K, 496L, 498P, 501W, 506P, 666E, 684D, 685F, 686N, 688S, 751V, 752I, 753S, 754Y, 757Y, 759M, 760D, 761D, 898K, 900V, 902S, 924N, 926H, 929P, 932M, 937F, 941L, 958W, 989S, 997R, 998V, 999D, 1,001Y, 1,014V, 1,017K, 1,018F, 1,019Q, 1,021R, 1,022S, 1,043I, 1,044R, 1,045V, 1,049E, 1,051D, 1,052A, 1,054I, 1,056H, 1,057G, 1,058T, 1,059A, 1,060Y, 1,061L, 1,063Q, 1,064D, 1,065R, 1,066L, 1,067L, 1,068N, 1,072Y, 1,145P, 1,149K, 1,151L, 1,153S, 1,154E, 1,156A, 1,158M, 1,159G, 1,160I, 1,161K, 1,163R
CDD
cd00653 (RNA_pol_B_RPB2)

759M

RPB1 interaction site
492T, 494R, 495K, 496L, 498P, 501W, 506P, 666E, 684D, 685F, 686N, 688S, 751V, 752I, 753S, 754Y, 757Y, 759M, 760D, 761D, 898K, 900V, 902S, 924N, 926H, 929P, 932M, 937F, 941L, 958W, 989S, 997R, 998V, 999D, 1,001Y, 1,014V, 1,017K, 1,018F, 1,019Q, 1,021R, 1,022S, 1,043I, 1,044R, 1,045V, 1,049E, 1,051D, 1,052A, 1,054I, 1,056H, 1,057G, 1,058T, 1,059A, 1,060Y, 1,061L, 1,063Q, 1,064D, 1,065R, 1,066L, 1,067L, 1,068N, 1,072Y, 1,145P, 1,149K, 1,151L, 1,153S, 1,154E, 1,156A, 1,158M, 1,159G, 1,160I, 1,161K, 1,163R
CDD
cd00653 (RNA_pol_B_RPB2)

760D

RPB1 interaction site
492T, 494R, 495K, 496L, 498P, 501W, 506P, 666E, 684D, 685F, 686N, 688S, 751V, 752I, 753S, 754Y, 757Y, 759M, 760D, 761D, 898K, 900V, 902S, 924N, 926H, 929P, 932M, 937F, 941L, 958W, 989S, 997R, 998V, 999D, 1,001Y, 1,014V, 1,017K, 1,018F, 1,019Q, 1,021R, 1,022S, 1,043I, 1,044R, 1,045V, 1,049E, 1,051D, 1,052A, 1,054I, 1,056H, 1,057G, 1,058T, 1,059A, 1,060Y, 1,061L, 1,063Q, 1,064D, 1,065R, 1,066L, 1,067L, 1,068N, 1,072Y, 1,145P, 1,149K, 1,151L, 1,153S, 1,154E, 1,156A, 1,158M, 1,159G, 1,160I, 1,161K, 1,163R
CDD
cd00653 (RNA_pol_B_RPB2)

761D

RPB1 interaction site
492T, 494R, 495K, 496L, 498P, 501W, 506P, 666E, 684D, 685F, 686N, 688S, 751V, 752I, 753S, 754Y, 757Y, 759M, 760D, 761D, 898K, 900V, 902S, 924N, 926H, 929P, 932M, 937F, 941L, 958W, 989S, 997R, 998V, 999D, 1,001Y, 1,014V, 1,017K, 1,018F, 1,019Q, 1,021R, 1,022S, 1,043I, 1,044R, 1,045V, 1,049E, 1,051D, 1,052A, 1,054I, 1,056H, 1,057G, 1,058T, 1,059A, 1,060Y, 1,061L, 1,063Q, 1,064D, 1,065R, 1,066L, 1,067L, 1,068N, 1,072Y, 1,145P, 1,149K, 1,151L, 1,153S, 1,154E, 1,156A, 1,158M, 1,159G, 1,160I, 1,161K, 1,163R
CDD
cd00653 (RNA_pol_B_RPB2)

898K

RPB1 interaction site
492T, 494R, 495K, 496L, 498P, 501W, 506P, 666E, 684D, 685F, 686N, 688S, 751V, 752I, 753S, 754Y, 757Y, 759M, 760D, 761D, 898K, 900V, 902S, 924N, 926H, 929P, 932M, 937F, 941L, 958W, 989S, 997R, 998V, 999D, 1,001Y, 1,014V, 1,017K, 1,018F, 1,019Q, 1,021R, 1,022S, 1,043I, 1,044R, 1,045V, 1,049E, 1,051D, 1,052A, 1,054I, 1,056H, 1,057G, 1,058T, 1,059A, 1,060Y, 1,061L, 1,063Q, 1,064D, 1,065R, 1,066L, 1,067L, 1,068N, 1,072Y, 1,145P, 1,149K, 1,151L, 1,153S, 1,154E, 1,156A, 1,158M, 1,159G, 1,160I, 1,161K, 1,163R
CDD
cd00653 (RNA_pol_B_RPB2)

900V

RPB1 interaction site
492T, 494R, 495K, 496L, 498P, 501W, 506P, 666E, 684D, 685F, 686N, 688S, 751V, 752I, 753S, 754Y, 757Y, 759M, 760D, 761D, 898K, 900V, 902S, 924N, 926H, 929P, 932M, 937F, 941L, 958W, 989S, 997R, 998V, 999D, 1,001Y, 1,014V, 1,017K, 1,018F, 1,019Q, 1,021R, 1,022S, 1,043I, 1,044R, 1,045V, 1,049E, 1,051D, 1,052A, 1,054I, 1,056H, 1,057G, 1,058T, 1,059A, 1,060Y, 1,061L, 1,063Q, 1,064D, 1,065R, 1,066L, 1,067L, 1,068N, 1,072Y, 1,145P, 1,149K, 1,151L, 1,153S, 1,154E, 1,156A, 1,158M, 1,159G, 1,160I, 1,161K, 1,163R
CDD
cd00653 (RNA_pol_B_RPB2)

902S

RPB1 interaction site
492T, 494R, 495K, 496L, 498P, 501W, 506P, 666E, 684D, 685F, 686N, 688S, 751V, 752I, 753S, 754Y, 757Y, 759M, 760D, 761D, 898K, 900V, 902S, 924N, 926H, 929P, 932M, 937F, 941L, 958W, 989S, 997R, 998V, 999D, 1,001Y, 1,014V, 1,017K, 1,018F, 1,019Q, 1,021R, 1,022S, 1,043I, 1,044R, 1,045V, 1,049E, 1,051D, 1,052A, 1,054I, 1,056H, 1,057G, 1,058T, 1,059A, 1,060Y, 1,061L, 1,063Q, 1,064D, 1,065R, 1,066L, 1,067L, 1,068N, 1,072Y, 1,145P, 1,149K, 1,151L, 1,153S, 1,154E, 1,156A, 1,158M, 1,159G, 1,160I, 1,161K, 1,163R
CDD
cd00653 (RNA_pol_B_RPB2)

924N

RPB1 interaction site
492T, 494R, 495K, 496L, 498P, 501W, 506P, 666E, 684D, 685F, 686N, 688S, 751V, 752I, 753S, 754Y, 757Y, 759M, 760D, 761D, 898K, 900V, 902S, 924N, 926H, 929P, 932M, 937F, 941L, 958W, 989S, 997R, 998V, 999D, 1,001Y, 1,014V, 1,017K, 1,018F, 1,019Q, 1,021R, 1,022S, 1,043I, 1,044R, 1,045V, 1,049E, 1,051D, 1,052A, 1,054I, 1,056H, 1,057G, 1,058T, 1,059A, 1,060Y, 1,061L, 1,063Q, 1,064D, 1,065R, 1,066L, 1,067L, 1,068N, 1,072Y, 1,145P, 1,149K, 1,151L, 1,153S, 1,154E, 1,156A, 1,158M, 1,159G, 1,160I, 1,161K, 1,163R
CDD
cd00653 (RNA_pol_B_RPB2)

926H

RPB1 interaction site
492T, 494R, 495K, 496L, 498P, 501W, 506P, 666E, 684D, 685F, 686N, 688S, 751V, 752I, 753S, 754Y, 757Y, 759M, 760D, 761D, 898K, 900V, 902S, 924N, 926H, 929P, 932M, 937F, 941L, 958W, 989S, 997R, 998V, 999D, 1,001Y, 1,014V, 1,017K, 1,018F, 1,019Q, 1,021R, 1,022S, 1,043I, 1,044R, 1,045V, 1,049E, 1,051D, 1,052A, 1,054I, 1,056H, 1,057G, 1,058T, 1,059A, 1,060Y, 1,061L, 1,063Q, 1,064D, 1,065R, 1,066L, 1,067L, 1,068N, 1,072Y, 1,145P, 1,149K, 1,151L, 1,153S, 1,154E, 1,156A, 1,158M, 1,159G, 1,160I, 1,161K, 1,163R
CDD
cd00653 (RNA_pol_B_RPB2)

929P

RPB1 interaction site
492T, 494R, 495K, 496L, 498P, 501W, 506P, 666E, 684D, 685F, 686N, 688S, 751V, 752I, 753S, 754Y, 757Y, 759M, 760D, 761D, 898K, 900V, 902S, 924N, 926H, 929P, 932M, 937F, 941L, 958W, 989S, 997R, 998V, 999D, 1,001Y, 1,014V, 1,017K, 1,018F, 1,019Q, 1,021R, 1,022S, 1,043I, 1,044R, 1,045V, 1,049E, 1,051D, 1,052A, 1,054I, 1,056H, 1,057G, 1,058T, 1,059A, 1,060Y, 1,061L, 1,063Q, 1,064D, 1,065R, 1,066L, 1,067L, 1,068N, 1,072Y, 1,145P, 1,149K, 1,151L, 1,153S, 1,154E, 1,156A, 1,158M, 1,159G, 1,160I, 1,161K, 1,163R
CDD
cd00653 (RNA_pol_B_RPB2)

932M

RPB1 interaction site
492T, 494R, 495K, 496L, 498P, 501W, 506P, 666E, 684D, 685F, 686N, 688S, 751V, 752I, 753S, 754Y, 757Y, 759M, 760D, 761D, 898K, 900V, 902S, 924N, 926H, 929P, 932M, 937F, 941L, 958W, 989S, 997R, 998V, 999D, 1,001Y, 1,014V, 1,017K, 1,018F, 1,019Q, 1,021R, 1,022S, 1,043I, 1,044R, 1,045V, 1,049E, 1,051D, 1,052A, 1,054I, 1,056H, 1,057G, 1,058T, 1,059A, 1,060Y, 1,061L, 1,063Q, 1,064D, 1,065R, 1,066L, 1,067L, 1,068N, 1,072Y, 1,145P, 1,149K, 1,151L, 1,153S, 1,154E, 1,156A, 1,158M, 1,159G, 1,160I, 1,161K, 1,163R
CDD
cd00653 (RNA_pol_B_RPB2)

937F

RPB1 interaction site
492T, 494R, 495K, 496L, 498P, 501W, 506P, 666E, 684D, 685F, 686N, 688S, 751V, 752I, 753S, 754Y, 757Y, 759M, 760D, 761D, 898K, 900V, 902S, 924N, 926H, 929P, 932M, 937F, 941L, 958W, 989S, 997R, 998V, 999D, 1,001Y, 1,014V, 1,017K, 1,018F, 1,019Q, 1,021R, 1,022S, 1,043I, 1,044R, 1,045V, 1,049E, 1,051D, 1,052A, 1,054I, 1,056H, 1,057G, 1,058T, 1,059A, 1,060Y, 1,061L, 1,063Q, 1,064D, 1,065R, 1,066L, 1,067L, 1,068N, 1,072Y, 1,145P, 1,149K, 1,151L, 1,153S, 1,154E, 1,156A, 1,158M, 1,159G, 1,160I, 1,161K, 1,163R
CDD
cd00653 (RNA_pol_B_RPB2)

941L

RPB1 interaction site
492T, 494R, 495K, 496L, 498P, 501W, 506P, 666E, 684D, 685F, 686N, 688S, 751V, 752I, 753S, 754Y, 757Y, 759M, 760D, 761D, 898K, 900V, 902S, 924N, 926H, 929P, 932M, 937F, 941L, 958W, 989S, 997R, 998V, 999D, 1,001Y, 1,014V, 1,017K, 1,018F, 1,019Q, 1,021R, 1,022S, 1,043I, 1,044R, 1,045V, 1,049E, 1,051D, 1,052A, 1,054I, 1,056H, 1,057G, 1,058T, 1,059A, 1,060Y, 1,061L, 1,063Q, 1,064D, 1,065R, 1,066L, 1,067L, 1,068N, 1,072Y, 1,145P, 1,149K, 1,151L, 1,153S, 1,154E, 1,156A, 1,158M, 1,159G, 1,160I, 1,161K, 1,163R
CDD
cd00653 (RNA_pol_B_RPB2)

958W

RPB1 interaction site
492T, 494R, 495K, 496L, 498P, 501W, 506P, 666E, 684D, 685F, 686N, 688S, 751V, 752I, 753S, 754Y, 757Y, 759M, 760D, 761D, 898K, 900V, 902S, 924N, 926H, 929P, 932M, 937F, 941L, 958W, 989S, 997R, 998V, 999D, 1,001Y, 1,014V, 1,017K, 1,018F, 1,019Q, 1,021R, 1,022S, 1,043I, 1,044R, 1,045V, 1,049E, 1,051D, 1,052A, 1,054I, 1,056H, 1,057G, 1,058T, 1,059A, 1,060Y, 1,061L, 1,063Q, 1,064D, 1,065R, 1,066L, 1,067L, 1,068N, 1,072Y, 1,145P, 1,149K, 1,151L, 1,153S, 1,154E, 1,156A, 1,158M, 1,159G, 1,160I, 1,161K, 1,163R
CDD
cd00653 (RNA_pol_B_RPB2)

989S

RPB1 interaction site
492T, 494R, 495K, 496L, 498P, 501W, 506P, 666E, 684D, 685F, 686N, 688S, 751V, 752I, 753S, 754Y, 757Y, 759M, 760D, 761D, 898K, 900V, 902S, 924N, 926H, 929P, 932M, 937F, 941L, 958W, 989S, 997R, 998V, 999D, 1,001Y, 1,014V, 1,017K, 1,018F, 1,019Q, 1,021R, 1,022S, 1,043I, 1,044R, 1,045V, 1,049E, 1,051D, 1,052A, 1,054I, 1,056H, 1,057G, 1,058T, 1,059A, 1,060Y, 1,061L, 1,063Q, 1,064D, 1,065R, 1,066L, 1,067L, 1,068N, 1,072Y, 1,145P, 1,149K, 1,151L, 1,153S, 1,154E, 1,156A, 1,158M, 1,159G, 1,160I, 1,161K, 1,163R
CDD
cd00653 (RNA_pol_B_RPB2)

997R

RPB1 interaction site
492T, 494R, 495K, 496L, 498P, 501W, 506P, 666E, 684D, 685F, 686N, 688S, 751V, 752I, 753S, 754Y, 757Y, 759M, 760D, 761D, 898K, 900V, 902S, 924N, 926H, 929P, 932M, 937F, 941L, 958W, 989S, 997R, 998V, 999D, 1,001Y, 1,014V, 1,017K, 1,018F, 1,019Q, 1,021R, 1,022S, 1,043I, 1,044R, 1,045V, 1,049E, 1,051D, 1,052A, 1,054I, 1,056H, 1,057G, 1,058T, 1,059A, 1,060Y, 1,061L, 1,063Q, 1,064D, 1,065R, 1,066L, 1,067L, 1,068N, 1,072Y, 1,145P, 1,149K, 1,151L, 1,153S, 1,154E, 1,156A, 1,158M, 1,159G, 1,160I, 1,161K, 1,163R
CDD
cd00653 (RNA_pol_B_RPB2)

998V

RPB1 interaction site
492T, 494R, 495K, 496L, 498P, 501W, 506P, 666E, 684D, 685F, 686N, 688S, 751V, 752I, 753S, 754Y, 757Y, 759M, 760D, 761D, 898K, 900V, 902S, 924N, 926H, 929P, 932M, 937F, 941L, 958W, 989S, 997R, 998V, 999D, 1,001Y, 1,014V, 1,017K, 1,018F, 1,019Q, 1,021R, 1,022S, 1,043I, 1,044R, 1,045V, 1,049E, 1,051D, 1,052A, 1,054I, 1,056H, 1,057G, 1,058T, 1,059A, 1,060Y, 1,061L, 1,063Q, 1,064D, 1,065R, 1,066L, 1,067L, 1,068N, 1,072Y, 1,145P, 1,149K, 1,151L, 1,153S, 1,154E, 1,156A, 1,158M, 1,159G, 1,160I, 1,161K, 1,163R
CDD
cd00653 (RNA_pol_B_RPB2)

999D

RPB1 interaction site
492T, 494R, 495K, 496L, 498P, 501W, 506P, 666E, 684D, 685F, 686N, 688S, 751V, 752I, 753S, 754Y, 757Y, 759M, 760D, 761D, 898K, 900V, 902S, 924N, 926H, 929P, 932M, 937F, 941L, 958W, 989S, 997R, 998V, 999D, 1,001Y, 1,014V, 1,017K, 1,018F, 1,019Q, 1,021R, 1,022S, 1,043I, 1,044R, 1,045V, 1,049E, 1,051D, 1,052A, 1,054I, 1,056H, 1,057G, 1,058T, 1,059A, 1,060Y, 1,061L, 1,063Q, 1,064D, 1,065R, 1,066L, 1,067L, 1,068N, 1,072Y, 1,145P, 1,149K, 1,151L, 1,153S, 1,154E, 1,156A, 1,158M, 1,159G, 1,160I, 1,161K, 1,163R
CDD
cd00653 (RNA_pol_B_RPB2)

1,001Y

RPB1 interaction site
492T, 494R, 495K, 496L, 498P, 501W, 506P, 666E, 684D, 685F, 686N, 688S, 751V, 752I, 753S, 754Y, 757Y, 759M, 760D, 761D, 898K, 900V, 902S, 924N, 926H, 929P, 932M, 937F, 941L, 958W, 989S, 997R, 998V, 999D, 1,001Y, 1,014V, 1,017K, 1,018F, 1,019Q, 1,021R, 1,022S, 1,043I, 1,044R, 1,045V, 1,049E, 1,051D, 1,052A, 1,054I, 1,056H, 1,057G, 1,058T, 1,059A, 1,060Y, 1,061L, 1,063Q, 1,064D, 1,065R, 1,066L, 1,067L, 1,068N, 1,072Y, 1,145P, 1,149K, 1,151L, 1,153S, 1,154E, 1,156A, 1,158M, 1,159G, 1,160I, 1,161K, 1,163R
CDD
cd00653 (RNA_pol_B_RPB2)

1,014V

RPB1 interaction site
492T, 494R, 495K, 496L, 498P, 501W, 506P, 666E, 684D, 685F, 686N, 688S, 751V, 752I, 753S, 754Y, 757Y, 759M, 760D, 761D, 898K, 900V, 902S, 924N, 926H, 929P, 932M, 937F, 941L, 958W, 989S, 997R, 998V, 999D, 1,001Y, 1,014V, 1,017K, 1,018F, 1,019Q, 1,021R, 1,022S, 1,043I, 1,044R, 1,045V, 1,049E, 1,051D, 1,052A, 1,054I, 1,056H, 1,057G, 1,058T, 1,059A, 1,060Y, 1,061L, 1,063Q, 1,064D, 1,065R, 1,066L, 1,067L, 1,068N, 1,072Y, 1,145P, 1,149K, 1,151L, 1,153S, 1,154E, 1,156A, 1,158M, 1,159G, 1,160I, 1,161K, 1,163R
CDD
cd00653 (RNA_pol_B_RPB2)

1,017K

RPB1 interaction site
492T, 494R, 495K, 496L, 498P, 501W, 506P, 666E, 684D, 685F, 686N, 688S, 751V, 752I, 753S, 754Y, 757Y, 759M, 760D, 761D, 898K, 900V, 902S, 924N, 926H, 929P, 932M, 937F, 941L, 958W, 989S, 997R, 998V, 999D, 1,001Y, 1,014V, 1,017K, 1,018F, 1,019Q, 1,021R, 1,022S, 1,043I, 1,044R, 1,045V, 1,049E, 1,051D, 1,052A, 1,054I, 1,056H, 1,057G, 1,058T, 1,059A, 1,060Y, 1,061L, 1,063Q, 1,064D, 1,065R, 1,066L, 1,067L, 1,068N, 1,072Y, 1,145P, 1,149K, 1,151L, 1,153S, 1,154E, 1,156A, 1,158M, 1,159G, 1,160I, 1,161K, 1,163R
CDD
cd00653 (RNA_pol_B_RPB2)

1,018F

RPB1 interaction site
492T, 494R, 495K, 496L, 498P, 501W, 506P, 666E, 684D, 685F, 686N, 688S, 751V, 752I, 753S, 754Y, 757Y, 759M, 760D, 761D, 898K, 900V, 902S, 924N, 926H, 929P, 932M, 937F, 941L, 958W, 989S, 997R, 998V, 999D, 1,001Y, 1,014V, 1,017K, 1,018F, 1,019Q, 1,021R, 1,022S, 1,043I, 1,044R, 1,045V, 1,049E, 1,051D, 1,052A, 1,054I, 1,056H, 1,057G, 1,058T, 1,059A, 1,060Y, 1,061L, 1,063Q, 1,064D, 1,065R, 1,066L, 1,067L, 1,068N, 1,072Y, 1,145P, 1,149K, 1,151L, 1,153S, 1,154E, 1,156A, 1,158M, 1,159G, 1,160I, 1,161K, 1,163R
CDD
cd00653 (RNA_pol_B_RPB2)

1,019Q

RPB1 interaction site
492T, 494R, 495K, 496L, 498P, 501W, 506P, 666E, 684D, 685F, 686N, 688S, 751V, 752I, 753S, 754Y, 757Y, 759M, 760D, 761D, 898K, 900V, 902S, 924N, 926H, 929P, 932M, 937F, 941L, 958W, 989S, 997R, 998V, 999D, 1,001Y, 1,014V, 1,017K, 1,018F, 1,019Q, 1,021R, 1,022S, 1,043I, 1,044R, 1,045V, 1,049E, 1,051D, 1,052A, 1,054I, 1,056H, 1,057G, 1,058T, 1,059A, 1,060Y, 1,061L, 1,063Q, 1,064D, 1,065R, 1,066L, 1,067L, 1,068N, 1,072Y, 1,145P, 1,149K, 1,151L, 1,153S, 1,154E, 1,156A, 1,158M, 1,159G, 1,160I, 1,161K, 1,163R
CDD
cd00653 (RNA_pol_B_RPB2)

1,021R

RPB1 interaction site
492T, 494R, 495K, 496L, 498P, 501W, 506P, 666E, 684D, 685F, 686N, 688S, 751V, 752I, 753S, 754Y, 757Y, 759M, 760D, 761D, 898K, 900V, 902S, 924N, 926H, 929P, 932M, 937F, 941L, 958W, 989S, 997R, 998V, 999D, 1,001Y, 1,014V, 1,017K, 1,018F, 1,019Q, 1,021R, 1,022S, 1,043I, 1,044R, 1,045V, 1,049E, 1,051D, 1,052A, 1,054I, 1,056H, 1,057G, 1,058T, 1,059A, 1,060Y, 1,061L, 1,063Q, 1,064D, 1,065R, 1,066L, 1,067L, 1,068N, 1,072Y, 1,145P, 1,149K, 1,151L, 1,153S, 1,154E, 1,156A, 1,158M, 1,159G, 1,160I, 1,161K, 1,163R
CDD
cd00653 (RNA_pol_B_RPB2)

1,022S

RPB1 interaction site
492T, 494R, 495K, 496L, 498P, 501W, 506P, 666E, 684D, 685F, 686N, 688S, 751V, 752I, 753S, 754Y, 757Y, 759M, 760D, 761D, 898K, 900V, 902S, 924N, 926H, 929P, 932M, 937F, 941L, 958W, 989S, 997R, 998V, 999D, 1,001Y, 1,014V, 1,017K, 1,018F, 1,019Q, 1,021R, 1,022S, 1,043I, 1,044R, 1,045V, 1,049E, 1,051D, 1,052A, 1,054I, 1,056H, 1,057G, 1,058T, 1,059A, 1,060Y, 1,061L, 1,063Q, 1,064D, 1,065R, 1,066L, 1,067L, 1,068N, 1,072Y, 1,145P, 1,149K, 1,151L, 1,153S, 1,154E, 1,156A, 1,158M, 1,159G, 1,160I, 1,161K, 1,163R
CDD
cd00653 (RNA_pol_B_RPB2)

1,043I

RPB1 interaction site
492T, 494R, 495K, 496L, 498P, 501W, 506P, 666E, 684D, 685F, 686N, 688S, 751V, 752I, 753S, 754Y, 757Y, 759M, 760D, 761D, 898K, 900V, 902S, 924N, 926H, 929P, 932M, 937F, 941L, 958W, 989S, 997R, 998V, 999D, 1,001Y, 1,014V, 1,017K, 1,018F, 1,019Q, 1,021R, 1,022S, 1,043I, 1,044R, 1,045V, 1,049E, 1,051D, 1,052A, 1,054I, 1,056H, 1,057G, 1,058T, 1,059A, 1,060Y, 1,061L, 1,063Q, 1,064D, 1,065R, 1,066L, 1,067L, 1,068N, 1,072Y, 1,145P, 1,149K, 1,151L, 1,153S, 1,154E, 1,156A, 1,158M, 1,159G, 1,160I, 1,161K, 1,163R
CDD
cd00653 (RNA_pol_B_RPB2)

1,044R

RPB1 interaction site
492T, 494R, 495K, 496L, 498P, 501W, 506P, 666E, 684D, 685F, 686N, 688S, 751V, 752I, 753S, 754Y, 757Y, 759M, 760D, 761D, 898K, 900V, 902S, 924N, 926H, 929P, 932M, 937F, 941L, 958W, 989S, 997R, 998V, 999D, 1,001Y, 1,014V, 1,017K, 1,018F, 1,019Q, 1,021R, 1,022S, 1,043I, 1,044R, 1,045V, 1,049E, 1,051D, 1,052A, 1,054I, 1,056H, 1,057G, 1,058T, 1,059A, 1,060Y, 1,061L, 1,063Q, 1,064D, 1,065R, 1,066L, 1,067L, 1,068N, 1,072Y, 1,145P, 1,149K, 1,151L, 1,153S, 1,154E, 1,156A, 1,158M, 1,159G, 1,160I, 1,161K, 1,163R
CDD
cd00653 (RNA_pol_B_RPB2)

1,045V

RPB1 interaction site
492T, 494R, 495K, 496L, 498P, 501W, 506P, 666E, 684D, 685F, 686N, 688S, 751V, 752I, 753S, 754Y, 757Y, 759M, 760D, 761D, 898K, 900V, 902S, 924N, 926H, 929P, 932M, 937F, 941L, 958W, 989S, 997R, 998V, 999D, 1,001Y, 1,014V, 1,017K, 1,018F, 1,019Q, 1,021R, 1,022S, 1,043I, 1,044R, 1,045V, 1,049E, 1,051D, 1,052A, 1,054I, 1,056H, 1,057G, 1,058T, 1,059A, 1,060Y, 1,061L, 1,063Q, 1,064D, 1,065R, 1,066L, 1,067L, 1,068N, 1,072Y, 1,145P, 1,149K, 1,151L, 1,153S, 1,154E, 1,156A, 1,158M, 1,159G, 1,160I, 1,161K, 1,163R
CDD
cd00653 (RNA_pol_B_RPB2)

1,049E

RPB1 interaction site
492T, 494R, 495K, 496L, 498P, 501W, 506P, 666E, 684D, 685F, 686N, 688S, 751V, 752I, 753S, 754Y, 757Y, 759M, 760D, 761D, 898K, 900V, 902S, 924N, 926H, 929P, 932M, 937F, 941L, 958W, 989S, 997R, 998V, 999D, 1,001Y, 1,014V, 1,017K, 1,018F, 1,019Q, 1,021R, 1,022S, 1,043I, 1,044R, 1,045V, 1,049E, 1,051D, 1,052A, 1,054I, 1,056H, 1,057G, 1,058T, 1,059A, 1,060Y, 1,061L, 1,063Q, 1,064D, 1,065R, 1,066L, 1,067L, 1,068N, 1,072Y, 1,145P, 1,149K, 1,151L, 1,153S, 1,154E, 1,156A, 1,158M, 1,159G, 1,160I, 1,161K, 1,163R
CDD
cd00653 (RNA_pol_B_RPB2)

1,051D

RPB1 interaction site
492T, 494R, 495K, 496L, 498P, 501W, 506P, 666E, 684D, 685F, 686N, 688S, 751V, 752I, 753S, 754Y, 757Y, 759M, 760D, 761D, 898K, 900V, 902S, 924N, 926H, 929P, 932M, 937F, 941L, 958W, 989S, 997R, 998V, 999D, 1,001Y, 1,014V, 1,017K, 1,018F, 1,019Q, 1,021R, 1,022S, 1,043I, 1,044R, 1,045V, 1,049E, 1,051D, 1,052A, 1,054I, 1,056H, 1,057G, 1,058T, 1,059A, 1,060Y, 1,061L, 1,063Q, 1,064D, 1,065R, 1,066L, 1,067L, 1,068N, 1,072Y, 1,145P, 1,149K, 1,151L, 1,153S, 1,154E, 1,156A, 1,158M, 1,159G, 1,160I, 1,161K, 1,163R
CDD
cd00653 (RNA_pol_B_RPB2)

1,052A

RPB1 interaction site
492T, 494R, 495K, 496L, 498P, 501W, 506P, 666E, 684D, 685F, 686N, 688S, 751V, 752I, 753S, 754Y, 757Y, 759M, 760D, 761D, 898K, 900V, 902S, 924N, 926H, 929P, 932M, 937F, 941L, 958W, 989S, 997R, 998V, 999D, 1,001Y, 1,014V, 1,017K, 1,018F, 1,019Q, 1,021R, 1,022S, 1,043I, 1,044R, 1,045V, 1,049E, 1,051D, 1,052A, 1,054I, 1,056H, 1,057G, 1,058T, 1,059A, 1,060Y, 1,061L, 1,063Q, 1,064D, 1,065R, 1,066L, 1,067L, 1,068N, 1,072Y, 1,145P, 1,149K, 1,151L, 1,153S, 1,154E, 1,156A, 1,158M, 1,159G, 1,160I, 1,161K, 1,163R
CDD
cd00653 (RNA_pol_B_RPB2)

1,054I

RPB1 interaction site
492T, 494R, 495K, 496L, 498P, 501W, 506P, 666E, 684D, 685F, 686N, 688S, 751V, 752I, 753S, 754Y, 757Y, 759M, 760D, 761D, 898K, 900V, 902S, 924N, 926H, 929P, 932M, 937F, 941L, 958W, 989S, 997R, 998V, 999D, 1,001Y, 1,014V, 1,017K, 1,018F, 1,019Q, 1,021R, 1,022S, 1,043I, 1,044R, 1,045V, 1,049E, 1,051D, 1,052A, 1,054I, 1,056H, 1,057G, 1,058T, 1,059A, 1,060Y, 1,061L, 1,063Q, 1,064D, 1,065R, 1,066L, 1,067L, 1,068N, 1,072Y, 1,145P, 1,149K, 1,151L, 1,153S, 1,154E, 1,156A, 1,158M, 1,159G, 1,160I, 1,161K, 1,163R
CDD
cd00653 (RNA_pol_B_RPB2)

1,056H

RPB1 interaction site
492T, 494R, 495K, 496L, 498P, 501W, 506P, 666E, 684D, 685F, 686N, 688S, 751V, 752I, 753S, 754Y, 757Y, 759M, 760D, 761D, 898K, 900V, 902S, 924N, 926H, 929P, 932M, 937F, 941L, 958W, 989S, 997R, 998V, 999D, 1,001Y, 1,014V, 1,017K, 1,018F, 1,019Q, 1,021R, 1,022S, 1,043I, 1,044R, 1,045V, 1,049E, 1,051D, 1,052A, 1,054I, 1,056H, 1,057G, 1,058T, 1,059A, 1,060Y, 1,061L, 1,063Q, 1,064D, 1,065R, 1,066L, 1,067L, 1,068N, 1,072Y, 1,145P, 1,149K, 1,151L, 1,153S, 1,154E, 1,156A, 1,158M, 1,159G, 1,160I, 1,161K, 1,163R
CDD
cd00653 (RNA_pol_B_RPB2)

1,057G

RPB1 interaction site
492T, 494R, 495K, 496L, 498P, 501W, 506P, 666E, 684D, 685F, 686N, 688S, 751V, 752I, 753S, 754Y, 757Y, 759M, 760D, 761D, 898K, 900V, 902S, 924N, 926H, 929P, 932M, 937F, 941L, 958W, 989S, 997R, 998V, 999D, 1,001Y, 1,014V, 1,017K, 1,018F, 1,019Q, 1,021R, 1,022S, 1,043I, 1,044R, 1,045V, 1,049E, 1,051D, 1,052A, 1,054I, 1,056H, 1,057G, 1,058T, 1,059A, 1,060Y, 1,061L, 1,063Q, 1,064D, 1,065R, 1,066L, 1,067L, 1,068N, 1,072Y, 1,145P, 1,149K, 1,151L, 1,153S, 1,154E, 1,156A, 1,158M, 1,159G, 1,160I, 1,161K, 1,163R
CDD
cd00653 (RNA_pol_B_RPB2)

1,058T

RPB1 interaction site
492T, 494R, 495K, 496L, 498P, 501W, 506P, 666E, 684D, 685F, 686N, 688S, 751V, 752I, 753S, 754Y, 757Y, 759M, 760D, 761D, 898K, 900V, 902S, 924N, 926H, 929P, 932M, 937F, 941L, 958W, 989S, 997R, 998V, 999D, 1,001Y, 1,014V, 1,017K, 1,018F, 1,019Q, 1,021R, 1,022S, 1,043I, 1,044R, 1,045V, 1,049E, 1,051D, 1,052A, 1,054I, 1,056H, 1,057G, 1,058T, 1,059A, 1,060Y, 1,061L, 1,063Q, 1,064D, 1,065R, 1,066L, 1,067L, 1,068N, 1,072Y, 1,145P, 1,149K, 1,151L, 1,153S, 1,154E, 1,156A, 1,158M, 1,159G, 1,160I, 1,161K, 1,163R
CDD
cd00653 (RNA_pol_B_RPB2)

1,059A

RPB1 interaction site
492T, 494R, 495K, 496L, 498P, 501W, 506P, 666E, 684D, 685F, 686N, 688S, 751V, 752I, 753S, 754Y, 757Y, 759M, 760D, 761D, 898K, 900V, 902S, 924N, 926H, 929P, 932M, 937F, 941L, 958W, 989S, 997R, 998V, 999D, 1,001Y, 1,014V, 1,017K, 1,018F, 1,019Q, 1,021R, 1,022S, 1,043I, 1,044R, 1,045V, 1,049E, 1,051D, 1,052A, 1,054I, 1,056H, 1,057G, 1,058T, 1,059A, 1,060Y, 1,061L, 1,063Q, 1,064D, 1,065R, 1,066L, 1,067L, 1,068N, 1,072Y, 1,145P, 1,149K, 1,151L, 1,153S, 1,154E, 1,156A, 1,158M, 1,159G, 1,160I, 1,161K, 1,163R
CDD
cd00653 (RNA_pol_B_RPB2)

1,060Y

RPB1 interaction site
492T, 494R, 495K, 496L, 498P, 501W, 506P, 666E, 684D, 685F, 686N, 688S, 751V, 752I, 753S, 754Y, 757Y, 759M, 760D, 761D, 898K, 900V, 902S, 924N, 926H, 929P, 932M, 937F, 941L, 958W, 989S, 997R, 998V, 999D, 1,001Y, 1,014V, 1,017K, 1,018F, 1,019Q, 1,021R, 1,022S, 1,043I, 1,044R, 1,045V, 1,049E, 1,051D, 1,052A, 1,054I, 1,056H, 1,057G, 1,058T, 1,059A, 1,060Y, 1,061L, 1,063Q, 1,064D, 1,065R, 1,066L, 1,067L, 1,068N, 1,072Y, 1,145P, 1,149K, 1,151L, 1,153S, 1,154E, 1,156A, 1,158M, 1,159G, 1,160I, 1,161K, 1,163R
CDD
cd00653 (RNA_pol_B_RPB2)

1,061L

RPB1 interaction site
492T, 494R, 495K, 496L, 498P, 501W, 506P, 666E, 684D, 685F, 686N, 688S, 751V, 752I, 753S, 754Y, 757Y, 759M, 760D, 761D, 898K, 900V, 902S, 924N, 926H, 929P, 932M, 937F, 941L, 958W, 989S, 997R, 998V, 999D, 1,001Y, 1,014V, 1,017K, 1,018F, 1,019Q, 1,021R, 1,022S, 1,043I, 1,044R, 1,045V, 1,049E, 1,051D, 1,052A, 1,054I, 1,056H, 1,057G, 1,058T, 1,059A, 1,060Y, 1,061L, 1,063Q, 1,064D, 1,065R, 1,066L, 1,067L, 1,068N, 1,072Y, 1,145P, 1,149K, 1,151L, 1,153S, 1,154E, 1,156A, 1,158M, 1,159G, 1,160I, 1,161K, 1,163R
CDD
cd00653 (RNA_pol_B_RPB2)

1,063Q

RPB1 interaction site
492T, 494R, 495K, 496L, 498P, 501W, 506P, 666E, 684D, 685F, 686N, 688S, 751V, 752I, 753S, 754Y, 757Y, 759M, 760D, 761D, 898K, 900V, 902S, 924N, 926H, 929P, 932M, 937F, 941L, 958W, 989S, 997R, 998V, 999D, 1,001Y, 1,014V, 1,017K, 1,018F, 1,019Q, 1,021R, 1,022S, 1,043I, 1,044R, 1,045V, 1,049E, 1,051D, 1,052A, 1,054I, 1,056H, 1,057G, 1,058T, 1,059A, 1,060Y, 1,061L, 1,063Q, 1,064D, 1,065R, 1,066L, 1,067L, 1,068N, 1,072Y, 1,145P, 1,149K, 1,151L, 1,153S, 1,154E, 1,156A, 1,158M, 1,159G, 1,160I, 1,161K, 1,163R
CDD
cd00653 (RNA_pol_B_RPB2)

1,064D

RPB1 interaction site
492T, 494R, 495K, 496L, 498P, 501W, 506P, 666E, 684D, 685F, 686N, 688S, 751V, 752I, 753S, 754Y, 757Y, 759M, 760D, 761D, 898K, 900V, 902S, 924N, 926H, 929P, 932M, 937F, 941L, 958W, 989S, 997R, 998V, 999D, 1,001Y, 1,014V, 1,017K, 1,018F, 1,019Q, 1,021R, 1,022S, 1,043I, 1,044R, 1,045V, 1,049E, 1,051D, 1,052A, 1,054I, 1,056H, 1,057G, 1,058T, 1,059A, 1,060Y, 1,061L, 1,063Q, 1,064D, 1,065R, 1,066L, 1,067L, 1,068N, 1,072Y, 1,145P, 1,149K, 1,151L, 1,153S, 1,154E, 1,156A, 1,158M, 1,159G, 1,160I, 1,161K, 1,163R
CDD
cd00653 (RNA_pol_B_RPB2)

1,065R

RPB1 interaction site
492T, 494R, 495K, 496L, 498P, 501W, 506P, 666E, 684D, 685F, 686N, 688S, 751V, 752I, 753S, 754Y, 757Y, 759M, 760D, 761D, 898K, 900V, 902S, 924N, 926H, 929P, 932M, 937F, 941L, 958W, 989S, 997R, 998V, 999D, 1,001Y, 1,014V, 1,017K, 1,018F, 1,019Q, 1,021R, 1,022S, 1,043I, 1,044R, 1,045V, 1,049E, 1,051D, 1,052A, 1,054I, 1,056H, 1,057G, 1,058T, 1,059A, 1,060Y, 1,061L, 1,063Q, 1,064D, 1,065R, 1,066L, 1,067L, 1,068N, 1,072Y, 1,145P, 1,149K, 1,151L, 1,153S, 1,154E, 1,156A, 1,158M, 1,159G, 1,160I, 1,161K, 1,163R
CDD
cd00653 (RNA_pol_B_RPB2)

1,066L

RPB1 interaction site
492T, 494R, 495K, 496L, 498P, 501W, 506P, 666E, 684D, 685F, 686N, 688S, 751V, 752I, 753S, 754Y, 757Y, 759M, 760D, 761D, 898K, 900V, 902S, 924N, 926H, 929P, 932M, 937F, 941L, 958W, 989S, 997R, 998V, 999D, 1,001Y, 1,014V, 1,017K, 1,018F, 1,019Q, 1,021R, 1,022S, 1,043I, 1,044R, 1,045V, 1,049E, 1,051D, 1,052A, 1,054I, 1,056H, 1,057G, 1,058T, 1,059A, 1,060Y, 1,061L, 1,063Q, 1,064D, 1,065R, 1,066L, 1,067L, 1,068N, 1,072Y, 1,145P, 1,149K, 1,151L, 1,153S, 1,154E, 1,156A, 1,158M, 1,159G, 1,160I, 1,161K, 1,163R
CDD
cd00653 (RNA_pol_B_RPB2)

1,067L

RPB1 interaction site
492T, 494R, 495K, 496L, 498P, 501W, 506P, 666E, 684D, 685F, 686N, 688S, 751V, 752I, 753S, 754Y, 757Y, 759M, 760D, 761D, 898K, 900V, 902S, 924N, 926H, 929P, 932M, 937F, 941L, 958W, 989S, 997R, 998V, 999D, 1,001Y, 1,014V, 1,017K, 1,018F, 1,019Q, 1,021R, 1,022S, 1,043I, 1,044R, 1,045V, 1,049E, 1,051D, 1,052A, 1,054I, 1,056H, 1,057G, 1,058T, 1,059A, 1,060Y, 1,061L, 1,063Q, 1,064D, 1,065R, 1,066L, 1,067L, 1,068N, 1,072Y, 1,145P, 1,149K, 1,151L, 1,153S, 1,154E, 1,156A, 1,158M, 1,159G, 1,160I, 1,161K, 1,163R
CDD
cd00653 (RNA_pol_B_RPB2)

1,068N

RPB1 interaction site
492T, 494R, 495K, 496L, 498P, 501W, 506P, 666E, 684D, 685F, 686N, 688S, 751V, 752I, 753S, 754Y, 757Y, 759M, 760D, 761D, 898K, 900V, 902S, 924N, 926H, 929P, 932M, 937F, 941L, 958W, 989S, 997R, 998V, 999D, 1,001Y, 1,014V, 1,017K, 1,018F, 1,019Q, 1,021R, 1,022S, 1,043I, 1,044R, 1,045V, 1,049E, 1,051D, 1,052A, 1,054I, 1,056H, 1,057G, 1,058T, 1,059A, 1,060Y, 1,061L, 1,063Q, 1,064D, 1,065R, 1,066L, 1,067L, 1,068N, 1,072Y, 1,145P, 1,149K, 1,151L, 1,153S, 1,154E, 1,156A, 1,158M, 1,159G, 1,160I, 1,161K, 1,163R
CDD
cd00653 (RNA_pol_B_RPB2)

1,072Y

RPB1 interaction site
492T, 494R, 495K, 496L, 498P, 501W, 506P, 666E, 684D, 685F, 686N, 688S, 751V, 752I, 753S, 754Y, 757Y, 759M, 760D, 761D, 898K, 900V, 902S, 924N, 926H, 929P, 932M, 937F, 941L, 958W, 989S, 997R, 998V, 999D, 1,001Y, 1,014V, 1,017K, 1,018F, 1,019Q, 1,021R, 1,022S, 1,043I, 1,044R, 1,045V, 1,049E, 1,051D, 1,052A, 1,054I, 1,056H, 1,057G, 1,058T, 1,059A, 1,060Y, 1,061L, 1,063Q, 1,064D, 1,065R, 1,066L, 1,067L, 1,068N, 1,072Y, 1,145P, 1,149K, 1,151L, 1,153S, 1,154E, 1,156A, 1,158M, 1,159G, 1,160I, 1,161K, 1,163R
CDD
cd00653 (RNA_pol_B_RPB2)

1,145P

RPB1 interaction site
492T, 494R, 495K, 496L, 498P, 501W, 506P, 666E, 684D, 685F, 686N, 688S, 751V, 752I, 753S, 754Y, 757Y, 759M, 760D, 761D, 898K, 900V, 902S, 924N, 926H, 929P, 932M, 937F, 941L, 958W, 989S, 997R, 998V, 999D, 1,001Y, 1,014V, 1,017K, 1,018F, 1,019Q, 1,021R, 1,022S, 1,043I, 1,044R, 1,045V, 1,049E, 1,051D, 1,052A, 1,054I, 1,056H, 1,057G, 1,058T, 1,059A, 1,060Y, 1,061L, 1,063Q, 1,064D, 1,065R, 1,066L, 1,067L, 1,068N, 1,072Y, 1,145P, 1,149K, 1,151L, 1,153S, 1,154E, 1,156A, 1,158M, 1,159G, 1,160I, 1,161K, 1,163R
CDD
cd00653 (RNA_pol_B_RPB2)

1,149K

RPB1 interaction site
492T, 494R, 495K, 496L, 498P, 501W, 506P, 666E, 684D, 685F, 686N, 688S, 751V, 752I, 753S, 754Y, 757Y, 759M, 760D, 761D, 898K, 900V, 902S, 924N, 926H, 929P, 932M, 937F, 941L, 958W, 989S, 997R, 998V, 999D, 1,001Y, 1,014V, 1,017K, 1,018F, 1,019Q, 1,021R, 1,022S, 1,043I, 1,044R, 1,045V, 1,049E, 1,051D, 1,052A, 1,054I, 1,056H, 1,057G, 1,058T, 1,059A, 1,060Y, 1,061L, 1,063Q, 1,064D, 1,065R, 1,066L, 1,067L, 1,068N, 1,072Y, 1,145P, 1,149K, 1,151L, 1,153S, 1,154E, 1,156A, 1,158M, 1,159G, 1,160I, 1,161K, 1,163R
CDD
cd00653 (RNA_pol_B_RPB2)

1,151L

RPB1 interaction site
492T, 494R, 495K, 496L, 498P, 501W, 506P, 666E, 684D, 685F, 686N, 688S, 751V, 752I, 753S, 754Y, 757Y, 759M, 760D, 761D, 898K, 900V, 902S, 924N, 926H, 929P, 932M, 937F, 941L, 958W, 989S, 997R, 998V, 999D, 1,001Y, 1,014V, 1,017K, 1,018F, 1,019Q, 1,021R, 1,022S, 1,043I, 1,044R, 1,045V, 1,049E, 1,051D, 1,052A, 1,054I, 1,056H, 1,057G, 1,058T, 1,059A, 1,060Y, 1,061L, 1,063Q, 1,064D, 1,065R, 1,066L, 1,067L, 1,068N, 1,072Y, 1,145P, 1,149K, 1,151L, 1,153S, 1,154E, 1,156A, 1,158M, 1,159G, 1,160I, 1,161K, 1,163R
CDD
cd00653 (RNA_pol_B_RPB2)

1,153S

RPB1 interaction site
492T, 494R, 495K, 496L, 498P, 501W, 506P, 666E, 684D, 685F, 686N, 688S, 751V, 752I, 753S, 754Y, 757Y, 759M, 760D, 761D, 898K, 900V, 902S, 924N, 926H, 929P, 932M, 937F, 941L, 958W, 989S, 997R, 998V, 999D, 1,001Y, 1,014V, 1,017K, 1,018F, 1,019Q, 1,021R, 1,022S, 1,043I, 1,044R, 1,045V, 1,049E, 1,051D, 1,052A, 1,054I, 1,056H, 1,057G, 1,058T, 1,059A, 1,060Y, 1,061L, 1,063Q, 1,064D, 1,065R, 1,066L, 1,067L, 1,068N, 1,072Y, 1,145P, 1,149K, 1,151L, 1,153S, 1,154E, 1,156A, 1,158M, 1,159G, 1,160I, 1,161K, 1,163R
CDD
cd00653 (RNA_pol_B_RPB2)

1,154E

RPB1 interaction site
492T, 494R, 495K, 496L, 498P, 501W, 506P, 666E, 684D, 685F, 686N, 688S, 751V, 752I, 753S, 754Y, 757Y, 759M, 760D, 761D, 898K, 900V, 902S, 924N, 926H, 929P, 932M, 937F, 941L, 958W, 989S, 997R, 998V, 999D, 1,001Y, 1,014V, 1,017K, 1,018F, 1,019Q, 1,021R, 1,022S, 1,043I, 1,044R, 1,045V, 1,049E, 1,051D, 1,052A, 1,054I, 1,056H, 1,057G, 1,058T, 1,059A, 1,060Y, 1,061L, 1,063Q, 1,064D, 1,065R, 1,066L, 1,067L, 1,068N, 1,072Y, 1,145P, 1,149K, 1,151L, 1,153S, 1,154E, 1,156A, 1,158M, 1,159G, 1,160I, 1,161K, 1,163R
CDD
cd00653 (RNA_pol_B_RPB2)

1,156A

RPB1 interaction site
492T, 494R, 495K, 496L, 498P, 501W, 506P, 666E, 684D, 685F, 686N, 688S, 751V, 752I, 753S, 754Y, 757Y, 759M, 760D, 761D, 898K, 900V, 902S, 924N, 926H, 929P, 932M, 937F, 941L, 958W, 989S, 997R, 998V, 999D, 1,001Y, 1,014V, 1,017K, 1,018F, 1,019Q, 1,021R, 1,022S, 1,043I, 1,044R, 1,045V, 1,049E, 1,051D, 1,052A, 1,054I, 1,056H, 1,057G, 1,058T, 1,059A, 1,060Y, 1,061L, 1,063Q, 1,064D, 1,065R, 1,066L, 1,067L, 1,068N, 1,072Y, 1,145P, 1,149K, 1,151L, 1,153S, 1,154E, 1,156A, 1,158M, 1,159G, 1,160I, 1,161K, 1,163R
CDD
cd00653 (RNA_pol_B_RPB2)

1,158M

RPB1 interaction site
492T, 494R, 495K, 496L, 498P, 501W, 506P, 666E, 684D, 685F, 686N, 688S, 751V, 752I, 753S, 754Y, 757Y, 759M, 760D, 761D, 898K, 900V, 902S, 924N, 926H, 929P, 932M, 937F, 941L, 958W, 989S, 997R, 998V, 999D, 1,001Y, 1,014V, 1,017K, 1,018F, 1,019Q, 1,021R, 1,022S, 1,043I, 1,044R, 1,045V, 1,049E, 1,051D, 1,052A, 1,054I, 1,056H, 1,057G, 1,058T, 1,059A, 1,060Y, 1,061L, 1,063Q, 1,064D, 1,065R, 1,066L, 1,067L, 1,068N, 1,072Y, 1,145P, 1,149K, 1,151L, 1,153S, 1,154E, 1,156A, 1,158M, 1,159G, 1,160I, 1,161K, 1,163R
CDD
cd00653 (RNA_pol_B_RPB2)

1,159G

RPB1 interaction site
492T, 494R, 495K, 496L, 498P, 501W, 506P, 666E, 684D, 685F, 686N, 688S, 751V, 752I, 753S, 754Y, 757Y, 759M, 760D, 761D, 898K, 900V, 902S, 924N, 926H, 929P, 932M, 937F, 941L, 958W, 989S, 997R, 998V, 999D, 1,001Y, 1,014V, 1,017K, 1,018F, 1,019Q, 1,021R, 1,022S, 1,043I, 1,044R, 1,045V, 1,049E, 1,051D, 1,052A, 1,054I, 1,056H, 1,057G, 1,058T, 1,059A, 1,060Y, 1,061L, 1,063Q, 1,064D, 1,065R, 1,066L, 1,067L, 1,068N, 1,072Y, 1,145P, 1,149K, 1,151L, 1,153S, 1,154E, 1,156A, 1,158M, 1,159G, 1,160I, 1,161K, 1,163R
CDD
cd00653 (RNA_pol_B_RPB2)

1,160I

RPB1 interaction site
492T, 494R, 495K, 496L, 498P, 501W, 506P, 666E, 684D, 685F, 686N, 688S, 751V, 752I, 753S, 754Y, 757Y, 759M, 760D, 761D, 898K, 900V, 902S, 924N, 926H, 929P, 932M, 937F, 941L, 958W, 989S, 997R, 998V, 999D, 1,001Y, 1,014V, 1,017K, 1,018F, 1,019Q, 1,021R, 1,022S, 1,043I, 1,044R, 1,045V, 1,049E, 1,051D, 1,052A, 1,054I, 1,056H, 1,057G, 1,058T, 1,059A, 1,060Y, 1,061L, 1,063Q, 1,064D, 1,065R, 1,066L, 1,067L, 1,068N, 1,072Y, 1,145P, 1,149K, 1,151L, 1,153S, 1,154E, 1,156A, 1,158M, 1,159G, 1,160I, 1,161K, 1,163R
CDD
cd00653 (RNA_pol_B_RPB2)

1,161K

RPB1 interaction site
492T, 494R, 495K, 496L, 498P, 501W, 506P, 666E, 684D, 685F, 686N, 688S, 751V, 752I, 753S, 754Y, 757Y, 759M, 760D, 761D, 898K, 900V, 902S, 924N, 926H, 929P, 932M, 937F, 941L, 958W, 989S, 997R, 998V, 999D, 1,001Y, 1,014V, 1,017K, 1,018F, 1,019Q, 1,021R, 1,022S, 1,043I, 1,044R, 1,045V, 1,049E, 1,051D, 1,052A, 1,054I, 1,056H, 1,057G, 1,058T, 1,059A, 1,060Y, 1,061L, 1,063Q, 1,064D, 1,065R, 1,066L, 1,067L, 1,068N, 1,072Y, 1,145P, 1,149K, 1,151L, 1,153S, 1,154E, 1,156A, 1,158M, 1,159G, 1,160I, 1,161K, 1,163R
CDD
cd00653 (RNA_pol_B_RPB2)

1,163R

RPB1 interaction site
492T, 494R, 495K, 496L, 498P, 501W, 506P, 666E, 684D, 685F, 686N, 688S, 751V, 752I, 753S, 754Y, 757Y, 759M, 760D, 761D, 898K, 900V, 902S, 924N, 926H, 929P, 932M, 937F, 941L, 958W, 989S, 997R, 998V, 999D, 1,001Y, 1,014V, 1,017K, 1,018F, 1,019Q, 1,021R, 1,022S, 1,043I, 1,044R, 1,045V, 1,049E, 1,051D, 1,052A, 1,054I, 1,056H, 1,057G, 1,058T, 1,059A, 1,060Y, 1,061L, 1,063Q, 1,064D, 1,065R, 1,066L, 1,067L, 1,068N, 1,072Y, 1,145P, 1,149K, 1,151L, 1,153S, 1,154E, 1,156A, 1,158M, 1,159G, 1,160I, 1,161K, 1,163R
CDD
cd00653 (RNA_pol_B_RPB2)
RPB10 interaction ...

724Q

RPB10 interaction site
724Q, 725S, 746N, 748V, 769V, 772R, 907A, 920D, 947A, 948L, 950G, 985E, 1,002I
CDD
cd00653 (RNA_pol_B_RPB2)

725S

RPB10 interaction site
724Q, 725S, 746N, 748V, 769V, 772R, 907A, 920D, 947A, 948L, 950G, 985E, 1,002I
CDD
cd00653 (RNA_pol_B_RPB2)

746N

RPB10 interaction site
724Q, 725S, 746N, 748V, 769V, 772R, 907A, 920D, 947A, 948L, 950G, 985E, 1,002I
CDD
cd00653 (RNA_pol_B_RPB2)

748V

RPB10 interaction site
724Q, 725S, 746N, 748V, 769V, 772R, 907A, 920D, 947A, 948L, 950G, 985E, 1,002I
CDD
cd00653 (RNA_pol_B_RPB2)

769V

RPB10 interaction site
724Q, 725S, 746N, 748V, 769V, 772R, 907A, 920D, 947A, 948L, 950G, 985E, 1,002I
CDD
cd00653 (RNA_pol_B_RPB2)

772R

RPB10 interaction site
724Q, 725S, 746N, 748V, 769V, 772R, 907A, 920D, 947A, 948L, 950G, 985E, 1,002I
CDD
cd00653 (RNA_pol_B_RPB2)

907A

RPB10 interaction site
724Q, 725S, 746N, 748V, 769V, 772R, 907A, 920D, 947A, 948L, 950G, 985E, 1,002I
CDD
cd00653 (RNA_pol_B_RPB2)

920D

RPB10 interaction site
724Q, 725S, 746N, 748V, 769V, 772R, 907A, 920D, 947A, 948L, 950G, 985E, 1,002I
CDD
cd00653 (RNA_pol_B_RPB2)

947A

RPB10 interaction site
724Q, 725S, 746N, 748V, 769V, 772R, 907A, 920D, 947A, 948L, 950G, 985E, 1,002I
CDD
cd00653 (RNA_pol_B_RPB2)

948L

RPB10 interaction site
724Q, 725S, 746N, 748V, 769V, 772R, 907A, 920D, 947A, 948L, 950G, 985E, 1,002I
CDD
cd00653 (RNA_pol_B_RPB2)

950G

RPB10 interaction site
724Q, 725S, 746N, 748V, 769V, 772R, 907A, 920D, 947A, 948L, 950G, 985E, 1,002I
CDD
cd00653 (RNA_pol_B_RPB2)

985E

RPB10 interaction site
724Q, 725S, 746N, 748V, 769V, 772R, 907A, 920D, 947A, 948L, 950G, 985E, 1,002I
CDD
cd00653 (RNA_pol_B_RPB2)

1,002I

RPB10 interaction site
724Q, 725S, 746N, 748V, 769V, 772R, 907A, 920D, 947A, 948L, 950G, 985E, 1,002I
CDD
cd00653 (RNA_pol_B_RPB2)
RPB11 interaction ...

757Y

RPB11 interaction site
757Y, 771E, 906P, 991V
CDD
cd00653 (RNA_pol_B_RPB2)

771E

RPB11 interaction site
757Y, 771E, 906P, 991V
CDD
cd00653 (RNA_pol_B_RPB2)

906P

RPB11 interaction site
757Y, 771E, 906P, 991V
CDD
cd00653 (RNA_pol_B_RPB2)

991V

RPB11 interaction site
757Y, 771E, 906P, 991V
CDD
cd00653 (RNA_pol_B_RPB2)
RPB3 interaction s...

771E

RPB3 interaction site
771E, 772R, 776H, 880R, 882P, 907A, 908I, 909D, 912F, 914E, 915S, 990G, 991V, 992T, 993G, 994E, 995E, 996L, 997R, 999D
CDD
cd00653 (RNA_pol_B_RPB2)

772R

RPB3 interaction site
771E, 772R, 776H, 880R, 882P, 907A, 908I, 909D, 912F, 914E, 915S, 990G, 991V, 992T, 993G, 994E, 995E, 996L, 997R, 999D
CDD
cd00653 (RNA_pol_B_RPB2)

776H

RPB3 interaction site
771E, 772R, 776H, 880R, 882P, 907A, 908I, 909D, 912F, 914E, 915S, 990G, 991V, 992T, 993G, 994E, 995E, 996L, 997R, 999D
CDD
cd00653 (RNA_pol_B_RPB2)

880R

RPB3 interaction site
771E, 772R, 776H, 880R, 882P, 907A, 908I, 909D, 912F, 914E, 915S, 990G, 991V, 992T, 993G, 994E, 995E, 996L, 997R, 999D
CDD
cd00653 (RNA_pol_B_RPB2)

882P

RPB3 interaction site
771E, 772R, 776H, 880R, 882P, 907A, 908I, 909D, 912F, 914E, 915S, 990G, 991V, 992T, 993G, 994E, 995E, 996L, 997R, 999D
CDD
cd00653 (RNA_pol_B_RPB2)

907A

RPB3 interaction site
771E, 772R, 776H, 880R, 882P, 907A, 908I, 909D, 912F, 914E, 915S, 990G, 991V, 992T, 993G, 994E, 995E, 996L, 997R, 999D
CDD
cd00653 (RNA_pol_B_RPB2)

908I

RPB3 interaction site
771E, 772R, 776H, 880R, 882P, 907A, 908I, 909D, 912F, 914E, 915S, 990G, 991V, 992T, 993G, 994E, 995E, 996L, 997R, 999D
CDD
cd00653 (RNA_pol_B_RPB2)

909D

RPB3 interaction site
771E, 772R, 776H, 880R, 882P, 907A, 908I, 909D, 912F, 914E, 915S, 990G, 991V, 992T, 993G, 994E, 995E, 996L, 997R, 999D
CDD
cd00653 (RNA_pol_B_RPB2)

912F

RPB3 interaction site
771E, 772R, 776H, 880R, 882P, 907A, 908I, 909D, 912F, 914E, 915S, 990G, 991V, 992T, 993G, 994E, 995E, 996L, 997R, 999D
CDD
cd00653 (RNA_pol_B_RPB2)

914E

RPB3 interaction site
771E, 772R, 776H, 880R, 882P, 907A, 908I, 909D, 912F, 914E, 915S, 990G, 991V, 992T, 993G, 994E, 995E, 996L, 997R, 999D
CDD
cd00653 (RNA_pol_B_RPB2)

915S

RPB3 interaction site
771E, 772R, 776H, 880R, 882P, 907A, 908I, 909D, 912F, 914E, 915S, 990G, 991V, 992T, 993G, 994E, 995E, 996L, 997R, 999D
CDD
cd00653 (RNA_pol_B_RPB2)

990G

RPB3 interaction site
771E, 772R, 776H, 880R, 882P, 907A, 908I, 909D, 912F, 914E, 915S, 990G, 991V, 992T, 993G, 994E, 995E, 996L, 997R, 999D
CDD
cd00653 (RNA_pol_B_RPB2)

991V

RPB3 interaction site
771E, 772R, 776H, 880R, 882P, 907A, 908I, 909D, 912F, 914E, 915S, 990G, 991V, 992T, 993G, 994E, 995E, 996L, 997R, 999D
CDD
cd00653 (RNA_pol_B_RPB2)

992T

RPB3 interaction site
771E, 772R, 776H, 880R, 882P, 907A, 908I, 909D, 912F, 914E, 915S, 990G, 991V, 992T, 993G, 994E, 995E, 996L, 997R, 999D
CDD
cd00653 (RNA_pol_B_RPB2)

993G

RPB3 interaction site
771E, 772R, 776H, 880R, 882P, 907A, 908I, 909D, 912F, 914E, 915S, 990G, 991V, 992T, 993G, 994E, 995E, 996L, 997R, 999D
CDD
cd00653 (RNA_pol_B_RPB2)

994E

RPB3 interaction site
771E, 772R, 776H, 880R, 882P, 907A, 908I, 909D, 912F, 914E, 915S, 990G, 991V, 992T, 993G, 994E, 995E, 996L, 997R, 999D
CDD
cd00653 (RNA_pol_B_RPB2)

995E

RPB3 interaction site
771E, 772R, 776H, 880R, 882P, 907A, 908I, 909D, 912F, 914E, 915S, 990G, 991V, 992T, 993G, 994E, 995E, 996L, 997R, 999D
CDD
cd00653 (RNA_pol_B_RPB2)

996L

RPB3 interaction site
771E, 772R, 776H, 880R, 882P, 907A, 908I, 909D, 912F, 914E, 915S, 990G, 991V, 992T, 993G, 994E, 995E, 996L, 997R, 999D
CDD
cd00653 (RNA_pol_B_RPB2)

997R

RPB3 interaction site
771E, 772R, 776H, 880R, 882P, 907A, 908I, 909D, 912F, 914E, 915S, 990G, 991V, 992T, 993G, 994E, 995E, 996L, 997R, 999D
CDD
cd00653 (RNA_pol_B_RPB2)

999D

RPB3 interaction site
771E, 772R, 776H, 880R, 882P, 907A, 908I, 909D, 912F, 914E, 915S, 990G, 991V, 992T, 993G, 994E, 995E, 996L, 997R, 999D
CDD
cd00653 (RNA_pol_B_RPB2)

Protein sequence

>MIA_00439_1
MGASYHTLEREKYFRNPPTDKAFYPLLNAAVDPHVESFNALTEGPGGGLLNLGVKEIGTKVVFDNTSKEVLGNKLSYRID
NVQITKPAPRDMDKSTINRKTMPSECRERLTSYRGRLILRLGYRVNDGPEQFETIDAGMLPVMVKSNRCNLQGLSPAQLV
AAKEESEELGGYFVINGIEKLVRLLIVQRRNHPLAIIRPSFANRGRSYSKYGIQIRCVRPDQTSQSIVLHYLIDGNVTLR
FSWRKNEYLVPVVMILKALVETNDRAIFDGIVGNETSNSFLTDRLELLLRSFKSYNLYSQQETLAYLGDKFRVVFGSPPD
MSDVDVGREVLRKIVLVHLGDDNAAKFRMLLFMIRKLYALVSGECCADNPDAAQHQEILVGGFLYGMIIKEKIEEYLQNI
RLQVMSDLNGRTGVKFNDPKYIRRVLMRVNDNIGQKLHYFLSTGNLVSSSGLDLQQVSGYTVVAEKLNYHRFISHFRMVH
RGAFFAQLKTTTVRKLLPESWGFLCPVHTPDGSPCGLLNHLAHKCKIVTQPSDVSAVPQILADLGVSPPNSLASGPHSCV
VQLDGKVLGWTTHERGAQIANVLRYWKIAASDSKKLPVDLEVGYVPPSRGGQYPGLFLFSQQARMKRPVKYLPTGQEDWV
GPFEQVYMNIAITPSEIERDTHSHVEFSPTNILSILANMTPFSDFNQSPRNMYQCQMGKQTMGTPGTALIHRSDNKLYQL
QTGQSPIVRANLFDDYGLDNYPNGTNAVVAVISYTGYDMDDAMIINKSVHERGFGHGSIYKVDHINLDEKRRRGDPITMH
FGFGQDSWPEEWRNILDEDGLPMIGSMVTEGDPLCAYFDETLGKTKTICYKSSEVAFIEEVKLIGDEGDTEFQRFTVKLR
VPRAPVIGDKFSSRHGQKGVCSQKWPAIDMPFSESGMQPDVIINPHAFPSRMTIGMFVESLAGKAGALHGKAQDSTPWMF
SEENTAADYFGEQLIKAGYNYHGNEPMYSGVTGEELRVDIYIGLVFYQRLRHMVNDKFQVRSTGPVNSLTMQPVKGRKRH
GGIRVGEMERDALIGHGTAYLLQDRLLNCSDYTQTFMCTECGSLLTPQRSVPRVGGSPVVRCRRCARSHGFEESHTDTNT
VGDVWEDGSGKRFKGGDKIATVAVPYVLKYLDSELAAMGIKMRFSVTPKPAH

GO term prediction

Biological Process

GO:0006351 transcription, DNA-templated

Molecular Function

GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0032549 ribonucleoside binding

Cellular Component

GO:0005634 nucleus

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Entry type

Status

Per-residue features