Protein

MIA_00431_1

Length
553 amino acids


Browser: contig01:1230428-1232090+

Protein function

EGGNOG:0PG1ZPFS2Required for 3'-end cleavage and polyadenylation of pre- mRNAs. Also involved in chromosome segregation where it has a role in chromosome attachment to the mitotic spindle
SGD closest match:S000005261PFS2Polyadenylation factor subunit 2
CGD closest match:CAL0000196733PFS2Polyadenylation factor subunit 2

Protein alignments

%idAln lengthE-value
MCA_01979_176.190%3990.0MCA_01979_1
A0A0J9XGG2_GEOCN70.960%3960.0Similar to Saccharomyces cerevisiae YCR072C RSA4 WD-repeat protein involved in ribosome biogenesis OS=Geotrichum candidum GN=BN980_GECA16s00747g PE=4 SV=1
A0A060SZW9_BLAAD59.466%4124.51e-176ARAD1C11902p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C11902g PE=4 SV=1
A0A167C959_9ASCO61.671%4076.16e-174Pfs2p OS=Sugiyamaella lignohabitans GN=PFS2 PE=4 SV=1
A0A1E3PM31_9ASCO54.587%4361.18e-165WD40 repeat-like protein (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_23020 PE=4 SV=1
UniRef50_A0A1E3PM3154.587%4363.21e-162WD40 repeat-like protein (Fragment) n=1 Tax=Nadsonia fulvescens var. elongata DSM 6958 TaxID=857566 RepID=A0A1E3PM31_9ASCO
PFS2_YARLI49.428%4371.46e-139Polyadenylation factor subunit 2 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=PFS2 PE=3 SV=1
PFS2_CANAL48.926%4192.13e-138Polyadenylation factor subunit 2 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=PFS2 PE=3 SV=2
A0A1E4TG51_9ASCO44.226%4071.94e-125Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_31618 PE=4 SV=1
PFS2_YEAST47.110%3463.33e-107Polyadenylation factor subunit 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PFS2 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0065

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Repeat
  3. Repeat
1 100 200 300 400 500 553

Detailed signature matches

    1. SSF50978 (WD40 repe...)
    2. PS50294 (WD_REPEATS...)
    1. PF00400 (WD40)
    2. PS50082 (WD_REPEATS_2)
    3. SM00320 (WD40_4)
    1. PR00320 (GPROTEINBRPT)
Unintegrated signatures no IPR
Unintegrated signatures
  1. SSF81995 (beta-sand...)
  2. cd00200 (WD40)
  3. mobidb-lite (disord...)

Residue annotation

  1. structural tetrad ...

Protein sequence

>MIA_00431_1
MQQQQYPPQQQQQQQYQQQYQQQQYPQQYQQYQPQANSGANGEEEGPRKPTHRRTIDHGNSISRWMLERKLGLNKSGSSS
ASRASVYRVQAEPSYIVNLLPPQAYGGHAVSSFASKFVHTSINKLRVPILVVRWTPEGRRIVTGSRSGEFTLWNGMTFNF
ESIMQAHDNAICAMTHSHSDDWLLSGDREGTVKFWQPNFNNLNILQAHNEVVRDIAFSPNDAKFVTASDDSTLKIWNFND
SSEERTLTGHGWDVNCADWHPTLGLVASGSKDNLVKLWDPRVSGARAVVATYHGFKNTVTRTRFQRTGGQALLASGSKDQ
TVRVLDLRTLKDVVVLRGHNSDVCSLTWHPEHANLITTGTQHGSICHFLIDDPAQKEGGLLPAGKIVRAHEMAVWSLDYH
PLGHMLVSGANDKTTRIWARARPGDTIGFVDWYHTTPEAAAAAAAAGNPVPGAVGMSGVMGLPSGMIGGAAAAAATTAAA
AATAGAAAPATATPTGVAGVASGGGVGGMMGHGVAEDLRASSIKDGLQIDDGEIYAKKKKKTGSAIPGLGNVR

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0005515 protein binding

Cellular Component

None predicted.