Protein
MCA_01979_1
Length
458 amino acids
Gene name: PFS2
Description: Polyadenylation factor subunit 2
Browser: contigA:6020480-6021857+
RNA-seq: read pairs 1148, FPKM 30.9, percentile rank 53.6% (100% = highest expression)
Protein function
| Annotation: | PFS2 | Polyadenylation factor subunit 2 | |
|---|---|---|---|
| KEGG: | K15542 | PFS2 | polyadenylation factor subunit 2 |
| EGGNOG: | 0PG1Z | PFS2 | Required for 3'-end cleavage and polyadenylation of pre- mRNAs. Also involved in chromosome segregation where it has a role in chromosome attachment to the mitotic spindle |
| SGD closest match: | S000005261 | PFS2 | Polyadenylation factor subunit 2 |
| CGD closest match: | CAL0000196733 | PFS2 | Polyadenylation factor subunit 2 |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_00431_1 | 76.19% | 399 | 0.0 | MIA_00431_1 |
| A0A0J9XGG2_GEOCN | 73.67% | 395 | 0.0 | Similar to Saccharomyces cerevisiae YCR072C RSA4 WD-repeat protein involved in ribosome biogenesis OS=Geotrichum candidum GN=BN980_GECA16s00747g PE=4 SV=1 |
| A0A060SZW9_BLAAD | 62.19% | 402 | 0.0 | ARAD1C11902p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C11902g PE=4 SV=1 |
| A0A167C959_9ASCO | 59.82% | 438 | 0.0 | Pfs2p OS=Sugiyamaella lignohabitans GN=PFS2 PE=4 SV=1 |
| A0A1E3PM31_9ASCO | 55.73% | 436 | 7e-169 | WD40 repeat-like protein (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_23020 PE=4 SV=1 |
| UniRef50_A0A1E3PM31 | 55.73% | 436 | 2e-165 | WD40 repeat-like protein (Fragment) n=1 Tax=Nadsonia fulvescens var. elongata DSM 6958 TaxID=857566 RepID=A0A1E3PM31_9ASCO |
| PFS2_CANAL | 51.08% | 417 | 1e-143 | Polyadenylation factor subunit 2 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=PFS2 PE=3 SV=2 |
| PFS2_YARLI | 49.89% | 443 | 8e-141 | Polyadenylation factor subunit 2 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=PFS2 PE=3 SV=1 |
| A0A1E4TG51_9ASCO | 44.94% | 405 | 2e-126 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_31618 PE=4 SV=1 |
| PFS2_YEAST | 46.21% | 383 | 8e-113 | Polyadenylation factor subunit 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PFS2 PE=1 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.3943
Protein family membership
None predicted.
Domains and repeats
-
Domain
-
Repeat
-
Repeat
1
50
100
150
200
250
300
350
400
458
Detailed signature matches
-
-
PR00320 (GPROTEINBRPT)
-
no IPR
Unintegrated signatures
-
-
cd00200 (WD40)
-
mobidb-lite (disord...)
Residue annotation
-
structural tetrad ...
Protein sequence
>MCA_01979_1 MEEEYVRKPSHRRTVDHGNSISRLLLERKLGLTKFGSRSSIYRIQNEPSYIINLLPPQAYGDKAISSIPTKFIHTSINKI RCPIFVVKWTPEGRRIITGSMSGEFTLWNGMTFNFESIMQAHEDAIRAITHSHSDDWLLSGDRNGTVKFWQPNFNYLNSI QAHSEVVRDVAFSPNDSKFVTASDDSTLKIWNFNDASEERTLSGHNWDVKCADWHPTLGLIASGSKDNLVKLWDPRISGP RCIISTFHGFKNTITRTRFQKIGGQNLLASGSRDQTVRILDLRTMTDMAVLRGHNSDVCSLAWHPVNPNLLTTGTQLGSI CHFLLDTPLPENTVGLMPTGEIVRAHDQPGSVWSLDYHPLGHLLASGSNDKTTRIWARARPGDKNSFTDWYHTAPDDTHG MEGISVGPGSYRKYNNQAQTIEDGLDKSLLPETQNAFIPKPQSSSGSSGIPGIPGFNL
GO term prediction
Biological Process
None predicted.
Molecular Function
GO:0005515 protein binding
Cellular Component
None predicted.