Protein

MIA_00426_1

Length
260 amino acids

Browser: contig01:1217293-1218076+

Protein function

EGGNOG:0PI92FG08528.1Phosphoadenosine phosphosulfate reductase
SGD closest match:S000006371MET16Phosphoadenosine phosphosulfate reductase
CGD closest match:CAL0000192901MET16Phosphoadenylyl-sulfate reductase (Thioredoxin)

Protein alignments

%idAln lengthE-value
MCA_00822_174.046%2622.59e-149MCA_00822_1
A0A0J9X9L0_GEOCN72.112%2511.23e-141Similar to Saccharomyces cerevisiae YPR167C MET16 3'-phosphoadenylsulfate reductase, reduces 3'-phosphoadenylyl sulfate to adenosine-3',5'-bisphosphate OS=Geotrichum candidum GN=BN980_GECA06s00681g PE=4 SV=1
A0A167CSA0_9ASCO65.587%2471.51e-130Phosphoadenylyl-sulfate reductase (Thioredoxin) OS=Sugiyamaella lignohabitans GN=MET16 PE=4 SV=1
A0A060TAF9_BLAAD67.470%2492.37e-130ARAD1D26642p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D26642g PE=4 SV=1
A0A1E3PPL1_9ASCO62.302%2522.40e-121Phosphoadenosine phosphosulfate reductase thioredoxin OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_49784 PE=4 SV=1
Q6CFD3_YARLI64.228%2469.92e-121YALI0B08140p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B08140g PE=4 SV=1
UniRef50_A0A1A0H7B764.344%2444.20e-116Phosphoadenosine phosphosulfate reductase n=2 Tax=Fungi TaxID=4751 RepID=A0A1A0H7B7_9ASCO
Q5A0Z0_CANAL58.635%2492.39e-113Phosphoadenylyl-sulfate reductase (Thioredoxin) OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=MET16 PE=4 SV=1
A0A1E4TIQ7_9ASCO59.592%2451.04e-106Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_179 PE=4 SV=1
MET16_YEAST58.800%2503.40e-106Phosphoadenosine phosphosulfate reductase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MET16 PE=1 SV=2

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1679

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 260

Detailed signature matches

  1. Family IPR004511
    Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase
    1. TIGR00434
    2. PIRSF000857 (PAPS_r...)
  2. Family IPR011800
    Phosphoadenosine phosphosulphate reductase CysH
    1. TIGR02057
  3. Domain IPR014729
    Rossmann-like alpha/beta/alpha sandwich fold
    1. G3DSA:3.40.50...
  4. Domain IPR002500
    Phosphoadenosine phosphosulphate reductase
    1. PF01507 (PAPS_reduct)
    2. cd01713 (PAPS_reduc...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. NON_CYTOPLASM... (N...)
  3. SSF52402 (Adenine n...)
  4. TRANSMEMBRANE (Tran...)
  5. mobidb-lite (disord...)

Residue annotation

  1. Active Sites cd01713

Protein sequence

>MIA_00426_1
MTKDTIELTPSHLEYINSSLSNKSATEILQWSLMTFPGLFQTTAFGLTGLVILDMISKLAPGAHPIDLIFIDTLHHFKET
LELVERVKAKYPQINIHVYKPEGVSTEEEFAREYGEKLWDTNDTFYDYLVKVEPASRAYEELGVKAAITGRRRSQGGARA
KLQAVEYESDTKLIKINPLFNWTFQQVQQYIKENDIPYNALLDQGYRSVGDHHSTVPVKEGEDERAGRWKGKQKTECGIH
ETSRFAQFLAARNQQPQAQS

GO term prediction

Biological Process

GO:0008152 metabolic process
GO:0019379 sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin)
GO:0055114 oxidation-reduction process

Molecular Function

GO:0003824 catalytic activity
GO:0004604 phosphoadenylyl-sulfate reductase (thioredoxin) activity

Cellular Component

None predicted.