Protein

MCA_00822_1

Length
270 amino acids

Browser: contigA:2560281-2561094+

RNA-seq: read pairs 3949, FPKM 180.1, percentile rank 86.8% (100% = highest expression)

Protein function

KEGG:K00390cysH phosphoadenosine phosphosulfate reductase [EC:1.8.4.8 1.8.4.10]
EGGNOG:0PI92FG08528.1Phosphoadenosine phosphosulfate reductase
SGD closest match:S000006371MET16Phosphoadenosine phosphosulfate reductase
CGD closest match:CAL0000192901MET16Phosphoadenylyl-sulfate reductase (Thioredoxin)

Protein alignments

%idAln lengthE-value
MIA_00426_174.05%2626e-145MIA_00426_1
A0A0J9X9L0_GEOCN67.83%2583e-124Similar to Saccharomyces cerevisiae YPR167C MET16 3'-phosphoadenylsulfate reductase, reduces 3'-phosphoadenylyl sulfate to adenosine-3',5'-bisphosphate OS=Geotrichum candidum GN=BN980_GECA06s00681g PE=4 SV=1
A0A167CSA0_9ASCO62.64%2654e-121Phosphoadenylyl-sulfate reductase (Thioredoxin) OS=Sugiyamaella lignohabitans GN=MET16 PE=4 SV=1
UniRef50_A0A1A0H7B761.24%2584e-110Phosphoadenosine phosphosulfate reductase n=2 Tax=Fungi TaxID=4751 RepID=A0A1A0H7B7_9ASCO
A0A060TAF9_BLAAD59.02%2669e-112ARAD1D26642p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D26642g PE=4 SV=1
A0A1E3PPL1_9ASCO56.78%2731e-110Phosphoadenosine phosphosulfate reductase thioredoxin OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_49784 PE=4 SV=1
Q5A0Z0_CANAL58.53%2582e-109Phosphoadenylyl-sulfate reductase (Thioredoxin) OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=MET16 PE=4 SV=1
Q6CFD3_YARLI59.92%2572e-108YALI0B08140p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B08140g PE=4 SV=1
A0A1E4TIQ7_9ASCO57.53%2594e-104Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_179 PE=4 SV=1
MET16_YEAST55.64%2661e-100Phosphoadenosine phosphosulfate reductase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MET16 PE=1 SV=2

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1049

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 270

Detailed signature matches

  1. Family IPR004511
    Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase
    1. PIRSF000857 (PAPS_r...)
    2. TIGR00434
  2. Family IPR011800
    Phosphoadenosine phosphosulphate reductase CysH
    1. TIGR02057
  3. Domain IPR014729
    Rossmann-like alpha/beta/alpha sandwich fold
    1. G3DSA:3.40.50...
  4. Domain IPR002500
    Phosphoadenosine phosphosulphate reductase
    1. PF01507 (PAPS_reduct)
    2. cd01713 (PAPS_reduc...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. NON_CYTOPLASM... (N...)
  3. SSF52402 (Adenine n...)
  4. TRANSMEMBRANE (Tran...)

Residue annotation

  1. Active Sites cd01713

Protein sequence

>MCA_00822_1
MTRDSITLSSSHLQYINDSLADKTAEEILQWALITLPGLYQTTAFGLTGLVILDMISKLNNKFSNNNNNSNKKEHSHPID
LIFLDTLHHFPETLDLVSRVQEKYPGVNLHIYKPSKANTEEEFAAEYGPKLWETNDTFYDFLVKVEPAQRAYEELGVKAV
ITGRRRSQGGVRSKLQPVEFDPDTQLIKINPLYNWTFEQVKKYIDENEVPYNALLDQGYRSVGDYHSTVPVKEGEDERAG
RWKGKNKTECGIHETSRFAQFLKNNKVTQV

GO term prediction

Biological Process

GO:0008152 metabolic process
GO:0019379 sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin)
GO:0055114 oxidation-reduction process

Molecular Function

GO:0003824 catalytic activity
GO:0004604 phosphoadenylyl-sulfate reductase (thioredoxin) activity

Cellular Component

None predicted.