MIA_00423_1

Protein

Length

562 amino acids

Browser: contig01:1201279-1202968-

Protein function

EGGNOG:	0PFST	FG03636.1	MFS transporter (Seo1)
SGD closest match:	S000000062	SEO1	Probable transporter SEO1
CGD closest match:	CAL0000175721	CAALFM_CR06790CA	Uncharacterized protein

Protein alignments

	%id	Aln length	E-value
MCA_02572_1	61.441%	555	0.0	MCA_02572_1
UniRef50_F2QQK0	54.874%	554	0.0	Biotin symporter n=11 Tax=Saccharomycetales TaxID=4892 RepID=F2QQK0_KOMPC
A0A0J9XCA2_GEOCN	53.943%	558	0.0	Similar to Saccharomyces cerevisiae YAL067C SEO1 Putative permease OS=Geotrichum candidum GN=BN980_GECA09s00208g PE=4 SV=1
A0A1E3PTM8_9ASCO	54.376%	537	0.0	MFS general substrate transporter OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_49328 PE=4 SV=1
A0A060SWU6_BLAAD	55.960%	495	0.0	ARAD1A08228p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A08228g PE=4 SV=1
Q6C1T2_YARLI	48.452%	549	0.0	YALI0F13607p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F13607g PE=4 SV=1
Q59MT5_CANAL	45.439%	570	3.87e-178	Uncharacterized protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CAALFM_CR06790CA PE=4 SV=1
SEO1_YEAST	46.085%	562	4.52e-174	Probable transporter SEO1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SEO1 PE=1 SV=1
A0A167CNR4_9ASCO	28.137%	526	1.44e-66	Putative permease SEO1 OS=Sugiyamaella lignohabitans GN=SEO1 PE=4 SV=1
A0A1E4TD78_9ASCO	25.508%	443	1.09e-35	Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_142936 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0968

Protein family membership

Major facilitator superfamily (IPR011701)

Domains and repeats

Domain
102 - 538
Major facilitator superfamily domain (IPR020846)

1 100 200 300 400 500 562

Detailed signature matches

IPR011701

Major facilitator superfamily
1. PF07690 (MFS_1)
  
  125 - 486
  
  Pfam
  PF07690 (MFS_1)
IPR020846

Major facilitator superfamily domain
1. SSF103473 (MFS gene...)
  
  102 - 538
  
  SUPERFAMILY
  SSF103473 (MFS general substrate transporter)
2. cd06174 (MFS)
  
  117 - 529
  
  CDD
  cd06174 (MFS)

no IPR

Unintegrated signatures

CYTOPLASMIC_D... (C...)

534 - 562

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

179 - 184

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

467 - 477

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

1 - 110

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

234 - 244

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

412 - 417

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

301 - 352

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)
G3DSA:1.20.12...

337 - 546

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)

107 - 310

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)
NON_CYTOPLASM... (N...)

501 - 511

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

378 - 391

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

204 - 214

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

130 - 159

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

266 - 276

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

441 - 445

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)
TMhelix

355 - 377

TMHMM
TMhelix (TMhelix)

418 - 440

TMHMM
TMhelix (TMhelix)

444 - 466

TMHMM
TMhelix (TMhelix)

156 - 178

TMHMM
TMhelix (TMhelix)

212 - 234

TMHMM
TMhelix (TMhelix)

111 - 129

TMHMM
TMhelix (TMhelix)

185 - 202

TMHMM
TMhelix (TMhelix)

511 - 533

TMHMM
TMhelix (TMhelix)

478 - 500

TMHMM
TMhelix (TMhelix)

392 - 411

TMHMM
TMhelix (TMhelix)

246 - 263

TMHMM
TMhelix (TMhelix)

278 - 300

TMHMM
TMhelix (TMhelix)
TRANSMEMBRANE (Tran...)

160 - 178

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

277 - 300

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

512 - 533

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

478 - 500

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

446 - 466

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

215 - 233

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

111 - 129

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

185 - 203

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

353 - 377

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

418 - 440

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

245 - 265

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

392 - 411

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

Residue annotation

putative substrate...

134Q

putative substrate translocation pore
134Q, 137I, 138N, 139N, 141Y, 142V, 160T, 163Y, 164T, 167T, 171Q, 172I, 174M, 175M, 221E, 222S, 225Y, 226P, 229H, 230Y, 233G, 245A, 246G, 249Y, 250F, 256L, 364A, 367S, 368N, 371S, 372G, 375I, 389L, 393S, 397P, 400G, 404I, 452Q, 455G, 456W, 459S, 463Y, 464S, 467A, 480T, 481V, 484M, 485S, 488G, 489S, 492S
CDD
cd06174 (MFS)

137I

putative substrate translocation pore
134Q, 137I, 138N, 139N, 141Y, 142V, 160T, 163Y, 164T, 167T, 171Q, 172I, 174M, 175M, 221E, 222S, 225Y, 226P, 229H, 230Y, 233G, 245A, 246G, 249Y, 250F, 256L, 364A, 367S, 368N, 371S, 372G, 375I, 389L, 393S, 397P, 400G, 404I, 452Q, 455G, 456W, 459S, 463Y, 464S, 467A, 480T, 481V, 484M, 485S, 488G, 489S, 492S
CDD
cd06174 (MFS)

138N

putative substrate translocation pore
134Q, 137I, 138N, 139N, 141Y, 142V, 160T, 163Y, 164T, 167T, 171Q, 172I, 174M, 175M, 221E, 222S, 225Y, 226P, 229H, 230Y, 233G, 245A, 246G, 249Y, 250F, 256L, 364A, 367S, 368N, 371S, 372G, 375I, 389L, 393S, 397P, 400G, 404I, 452Q, 455G, 456W, 459S, 463Y, 464S, 467A, 480T, 481V, 484M, 485S, 488G, 489S, 492S
CDD
cd06174 (MFS)

139N

putative substrate translocation pore
134Q, 137I, 138N, 139N, 141Y, 142V, 160T, 163Y, 164T, 167T, 171Q, 172I, 174M, 175M, 221E, 222S, 225Y, 226P, 229H, 230Y, 233G, 245A, 246G, 249Y, 250F, 256L, 364A, 367S, 368N, 371S, 372G, 375I, 389L, 393S, 397P, 400G, 404I, 452Q, 455G, 456W, 459S, 463Y, 464S, 467A, 480T, 481V, 484M, 485S, 488G, 489S, 492S
CDD
cd06174 (MFS)

141Y

putative substrate translocation pore
134Q, 137I, 138N, 139N, 141Y, 142V, 160T, 163Y, 164T, 167T, 171Q, 172I, 174M, 175M, 221E, 222S, 225Y, 226P, 229H, 230Y, 233G, 245A, 246G, 249Y, 250F, 256L, 364A, 367S, 368N, 371S, 372G, 375I, 389L, 393S, 397P, 400G, 404I, 452Q, 455G, 456W, 459S, 463Y, 464S, 467A, 480T, 481V, 484M, 485S, 488G, 489S, 492S
CDD
cd06174 (MFS)

142V

putative substrate translocation pore
134Q, 137I, 138N, 139N, 141Y, 142V, 160T, 163Y, 164T, 167T, 171Q, 172I, 174M, 175M, 221E, 222S, 225Y, 226P, 229H, 230Y, 233G, 245A, 246G, 249Y, 250F, 256L, 364A, 367S, 368N, 371S, 372G, 375I, 389L, 393S, 397P, 400G, 404I, 452Q, 455G, 456W, 459S, 463Y, 464S, 467A, 480T, 481V, 484M, 485S, 488G, 489S, 492S
CDD
cd06174 (MFS)

160T

putative substrate translocation pore
134Q, 137I, 138N, 139N, 141Y, 142V, 160T, 163Y, 164T, 167T, 171Q, 172I, 174M, 175M, 221E, 222S, 225Y, 226P, 229H, 230Y, 233G, 245A, 246G, 249Y, 250F, 256L, 364A, 367S, 368N, 371S, 372G, 375I, 389L, 393S, 397P, 400G, 404I, 452Q, 455G, 456W, 459S, 463Y, 464S, 467A, 480T, 481V, 484M, 485S, 488G, 489S, 492S
CDD
cd06174 (MFS)

163Y

putative substrate translocation pore
134Q, 137I, 138N, 139N, 141Y, 142V, 160T, 163Y, 164T, 167T, 171Q, 172I, 174M, 175M, 221E, 222S, 225Y, 226P, 229H, 230Y, 233G, 245A, 246G, 249Y, 250F, 256L, 364A, 367S, 368N, 371S, 372G, 375I, 389L, 393S, 397P, 400G, 404I, 452Q, 455G, 456W, 459S, 463Y, 464S, 467A, 480T, 481V, 484M, 485S, 488G, 489S, 492S
CDD
cd06174 (MFS)

164T

putative substrate translocation pore
134Q, 137I, 138N, 139N, 141Y, 142V, 160T, 163Y, 164T, 167T, 171Q, 172I, 174M, 175M, 221E, 222S, 225Y, 226P, 229H, 230Y, 233G, 245A, 246G, 249Y, 250F, 256L, 364A, 367S, 368N, 371S, 372G, 375I, 389L, 393S, 397P, 400G, 404I, 452Q, 455G, 456W, 459S, 463Y, 464S, 467A, 480T, 481V, 484M, 485S, 488G, 489S, 492S
CDD
cd06174 (MFS)

167T

putative substrate translocation pore
134Q, 137I, 138N, 139N, 141Y, 142V, 160T, 163Y, 164T, 167T, 171Q, 172I, 174M, 175M, 221E, 222S, 225Y, 226P, 229H, 230Y, 233G, 245A, 246G, 249Y, 250F, 256L, 364A, 367S, 368N, 371S, 372G, 375I, 389L, 393S, 397P, 400G, 404I, 452Q, 455G, 456W, 459S, 463Y, 464S, 467A, 480T, 481V, 484M, 485S, 488G, 489S, 492S
CDD
cd06174 (MFS)

171Q

putative substrate translocation pore
134Q, 137I, 138N, 139N, 141Y, 142V, 160T, 163Y, 164T, 167T, 171Q, 172I, 174M, 175M, 221E, 222S, 225Y, 226P, 229H, 230Y, 233G, 245A, 246G, 249Y, 250F, 256L, 364A, 367S, 368N, 371S, 372G, 375I, 389L, 393S, 397P, 400G, 404I, 452Q, 455G, 456W, 459S, 463Y, 464S, 467A, 480T, 481V, 484M, 485S, 488G, 489S, 492S
CDD
cd06174 (MFS)

172I

putative substrate translocation pore
134Q, 137I, 138N, 139N, 141Y, 142V, 160T, 163Y, 164T, 167T, 171Q, 172I, 174M, 175M, 221E, 222S, 225Y, 226P, 229H, 230Y, 233G, 245A, 246G, 249Y, 250F, 256L, 364A, 367S, 368N, 371S, 372G, 375I, 389L, 393S, 397P, 400G, 404I, 452Q, 455G, 456W, 459S, 463Y, 464S, 467A, 480T, 481V, 484M, 485S, 488G, 489S, 492S
CDD
cd06174 (MFS)

174M

putative substrate translocation pore
134Q, 137I, 138N, 139N, 141Y, 142V, 160T, 163Y, 164T, 167T, 171Q, 172I, 174M, 175M, 221E, 222S, 225Y, 226P, 229H, 230Y, 233G, 245A, 246G, 249Y, 250F, 256L, 364A, 367S, 368N, 371S, 372G, 375I, 389L, 393S, 397P, 400G, 404I, 452Q, 455G, 456W, 459S, 463Y, 464S, 467A, 480T, 481V, 484M, 485S, 488G, 489S, 492S
CDD
cd06174 (MFS)

175M

putative substrate translocation pore
134Q, 137I, 138N, 139N, 141Y, 142V, 160T, 163Y, 164T, 167T, 171Q, 172I, 174M, 175M, 221E, 222S, 225Y, 226P, 229H, 230Y, 233G, 245A, 246G, 249Y, 250F, 256L, 364A, 367S, 368N, 371S, 372G, 375I, 389L, 393S, 397P, 400G, 404I, 452Q, 455G, 456W, 459S, 463Y, 464S, 467A, 480T, 481V, 484M, 485S, 488G, 489S, 492S
CDD
cd06174 (MFS)

221E

putative substrate translocation pore
134Q, 137I, 138N, 139N, 141Y, 142V, 160T, 163Y, 164T, 167T, 171Q, 172I, 174M, 175M, 221E, 222S, 225Y, 226P, 229H, 230Y, 233G, 245A, 246G, 249Y, 250F, 256L, 364A, 367S, 368N, 371S, 372G, 375I, 389L, 393S, 397P, 400G, 404I, 452Q, 455G, 456W, 459S, 463Y, 464S, 467A, 480T, 481V, 484M, 485S, 488G, 489S, 492S
CDD
cd06174 (MFS)

222S

putative substrate translocation pore
134Q, 137I, 138N, 139N, 141Y, 142V, 160T, 163Y, 164T, 167T, 171Q, 172I, 174M, 175M, 221E, 222S, 225Y, 226P, 229H, 230Y, 233G, 245A, 246G, 249Y, 250F, 256L, 364A, 367S, 368N, 371S, 372G, 375I, 389L, 393S, 397P, 400G, 404I, 452Q, 455G, 456W, 459S, 463Y, 464S, 467A, 480T, 481V, 484M, 485S, 488G, 489S, 492S
CDD
cd06174 (MFS)

225Y

putative substrate translocation pore
134Q, 137I, 138N, 139N, 141Y, 142V, 160T, 163Y, 164T, 167T, 171Q, 172I, 174M, 175M, 221E, 222S, 225Y, 226P, 229H, 230Y, 233G, 245A, 246G, 249Y, 250F, 256L, 364A, 367S, 368N, 371S, 372G, 375I, 389L, 393S, 397P, 400G, 404I, 452Q, 455G, 456W, 459S, 463Y, 464S, 467A, 480T, 481V, 484M, 485S, 488G, 489S, 492S
CDD
cd06174 (MFS)

226P

putative substrate translocation pore
134Q, 137I, 138N, 139N, 141Y, 142V, 160T, 163Y, 164T, 167T, 171Q, 172I, 174M, 175M, 221E, 222S, 225Y, 226P, 229H, 230Y, 233G, 245A, 246G, 249Y, 250F, 256L, 364A, 367S, 368N, 371S, 372G, 375I, 389L, 393S, 397P, 400G, 404I, 452Q, 455G, 456W, 459S, 463Y, 464S, 467A, 480T, 481V, 484M, 485S, 488G, 489S, 492S
CDD
cd06174 (MFS)

229H

putative substrate translocation pore
134Q, 137I, 138N, 139N, 141Y, 142V, 160T, 163Y, 164T, 167T, 171Q, 172I, 174M, 175M, 221E, 222S, 225Y, 226P, 229H, 230Y, 233G, 245A, 246G, 249Y, 250F, 256L, 364A, 367S, 368N, 371S, 372G, 375I, 389L, 393S, 397P, 400G, 404I, 452Q, 455G, 456W, 459S, 463Y, 464S, 467A, 480T, 481V, 484M, 485S, 488G, 489S, 492S
CDD
cd06174 (MFS)

230Y

putative substrate translocation pore
134Q, 137I, 138N, 139N, 141Y, 142V, 160T, 163Y, 164T, 167T, 171Q, 172I, 174M, 175M, 221E, 222S, 225Y, 226P, 229H, 230Y, 233G, 245A, 246G, 249Y, 250F, 256L, 364A, 367S, 368N, 371S, 372G, 375I, 389L, 393S, 397P, 400G, 404I, 452Q, 455G, 456W, 459S, 463Y, 464S, 467A, 480T, 481V, 484M, 485S, 488G, 489S, 492S
CDD
cd06174 (MFS)

233G

putative substrate translocation pore
134Q, 137I, 138N, 139N, 141Y, 142V, 160T, 163Y, 164T, 167T, 171Q, 172I, 174M, 175M, 221E, 222S, 225Y, 226P, 229H, 230Y, 233G, 245A, 246G, 249Y, 250F, 256L, 364A, 367S, 368N, 371S, 372G, 375I, 389L, 393S, 397P, 400G, 404I, 452Q, 455G, 456W, 459S, 463Y, 464S, 467A, 480T, 481V, 484M, 485S, 488G, 489S, 492S
CDD
cd06174 (MFS)

245A

putative substrate translocation pore
134Q, 137I, 138N, 139N, 141Y, 142V, 160T, 163Y, 164T, 167T, 171Q, 172I, 174M, 175M, 221E, 222S, 225Y, 226P, 229H, 230Y, 233G, 245A, 246G, 249Y, 250F, 256L, 364A, 367S, 368N, 371S, 372G, 375I, 389L, 393S, 397P, 400G, 404I, 452Q, 455G, 456W, 459S, 463Y, 464S, 467A, 480T, 481V, 484M, 485S, 488G, 489S, 492S
CDD
cd06174 (MFS)

246G

putative substrate translocation pore
134Q, 137I, 138N, 139N, 141Y, 142V, 160T, 163Y, 164T, 167T, 171Q, 172I, 174M, 175M, 221E, 222S, 225Y, 226P, 229H, 230Y, 233G, 245A, 246G, 249Y, 250F, 256L, 364A, 367S, 368N, 371S, 372G, 375I, 389L, 393S, 397P, 400G, 404I, 452Q, 455G, 456W, 459S, 463Y, 464S, 467A, 480T, 481V, 484M, 485S, 488G, 489S, 492S
CDD
cd06174 (MFS)

249Y

putative substrate translocation pore
134Q, 137I, 138N, 139N, 141Y, 142V, 160T, 163Y, 164T, 167T, 171Q, 172I, 174M, 175M, 221E, 222S, 225Y, 226P, 229H, 230Y, 233G, 245A, 246G, 249Y, 250F, 256L, 364A, 367S, 368N, 371S, 372G, 375I, 389L, 393S, 397P, 400G, 404I, 452Q, 455G, 456W, 459S, 463Y, 464S, 467A, 480T, 481V, 484M, 485S, 488G, 489S, 492S
CDD
cd06174 (MFS)

250F

putative substrate translocation pore
134Q, 137I, 138N, 139N, 141Y, 142V, 160T, 163Y, 164T, 167T, 171Q, 172I, 174M, 175M, 221E, 222S, 225Y, 226P, 229H, 230Y, 233G, 245A, 246G, 249Y, 250F, 256L, 364A, 367S, 368N, 371S, 372G, 375I, 389L, 393S, 397P, 400G, 404I, 452Q, 455G, 456W, 459S, 463Y, 464S, 467A, 480T, 481V, 484M, 485S, 488G, 489S, 492S
CDD
cd06174 (MFS)

256L

putative substrate translocation pore
134Q, 137I, 138N, 139N, 141Y, 142V, 160T, 163Y, 164T, 167T, 171Q, 172I, 174M, 175M, 221E, 222S, 225Y, 226P, 229H, 230Y, 233G, 245A, 246G, 249Y, 250F, 256L, 364A, 367S, 368N, 371S, 372G, 375I, 389L, 393S, 397P, 400G, 404I, 452Q, 455G, 456W, 459S, 463Y, 464S, 467A, 480T, 481V, 484M, 485S, 488G, 489S, 492S
CDD
cd06174 (MFS)

364A

putative substrate translocation pore
134Q, 137I, 138N, 139N, 141Y, 142V, 160T, 163Y, 164T, 167T, 171Q, 172I, 174M, 175M, 221E, 222S, 225Y, 226P, 229H, 230Y, 233G, 245A, 246G, 249Y, 250F, 256L, 364A, 367S, 368N, 371S, 372G, 375I, 389L, 393S, 397P, 400G, 404I, 452Q, 455G, 456W, 459S, 463Y, 464S, 467A, 480T, 481V, 484M, 485S, 488G, 489S, 492S
CDD
cd06174 (MFS)

367S

putative substrate translocation pore
134Q, 137I, 138N, 139N, 141Y, 142V, 160T, 163Y, 164T, 167T, 171Q, 172I, 174M, 175M, 221E, 222S, 225Y, 226P, 229H, 230Y, 233G, 245A, 246G, 249Y, 250F, 256L, 364A, 367S, 368N, 371S, 372G, 375I, 389L, 393S, 397P, 400G, 404I, 452Q, 455G, 456W, 459S, 463Y, 464S, 467A, 480T, 481V, 484M, 485S, 488G, 489S, 492S
CDD
cd06174 (MFS)

368N

putative substrate translocation pore
134Q, 137I, 138N, 139N, 141Y, 142V, 160T, 163Y, 164T, 167T, 171Q, 172I, 174M, 175M, 221E, 222S, 225Y, 226P, 229H, 230Y, 233G, 245A, 246G, 249Y, 250F, 256L, 364A, 367S, 368N, 371S, 372G, 375I, 389L, 393S, 397P, 400G, 404I, 452Q, 455G, 456W, 459S, 463Y, 464S, 467A, 480T, 481V, 484M, 485S, 488G, 489S, 492S
CDD
cd06174 (MFS)

371S

putative substrate translocation pore
134Q, 137I, 138N, 139N, 141Y, 142V, 160T, 163Y, 164T, 167T, 171Q, 172I, 174M, 175M, 221E, 222S, 225Y, 226P, 229H, 230Y, 233G, 245A, 246G, 249Y, 250F, 256L, 364A, 367S, 368N, 371S, 372G, 375I, 389L, 393S, 397P, 400G, 404I, 452Q, 455G, 456W, 459S, 463Y, 464S, 467A, 480T, 481V, 484M, 485S, 488G, 489S, 492S
CDD
cd06174 (MFS)

372G

putative substrate translocation pore
134Q, 137I, 138N, 139N, 141Y, 142V, 160T, 163Y, 164T, 167T, 171Q, 172I, 174M, 175M, 221E, 222S, 225Y, 226P, 229H, 230Y, 233G, 245A, 246G, 249Y, 250F, 256L, 364A, 367S, 368N, 371S, 372G, 375I, 389L, 393S, 397P, 400G, 404I, 452Q, 455G, 456W, 459S, 463Y, 464S, 467A, 480T, 481V, 484M, 485S, 488G, 489S, 492S
CDD
cd06174 (MFS)

375I

putative substrate translocation pore
134Q, 137I, 138N, 139N, 141Y, 142V, 160T, 163Y, 164T, 167T, 171Q, 172I, 174M, 175M, 221E, 222S, 225Y, 226P, 229H, 230Y, 233G, 245A, 246G, 249Y, 250F, 256L, 364A, 367S, 368N, 371S, 372G, 375I, 389L, 393S, 397P, 400G, 404I, 452Q, 455G, 456W, 459S, 463Y, 464S, 467A, 480T, 481V, 484M, 485S, 488G, 489S, 492S
CDD
cd06174 (MFS)

389L

putative substrate translocation pore
134Q, 137I, 138N, 139N, 141Y, 142V, 160T, 163Y, 164T, 167T, 171Q, 172I, 174M, 175M, 221E, 222S, 225Y, 226P, 229H, 230Y, 233G, 245A, 246G, 249Y, 250F, 256L, 364A, 367S, 368N, 371S, 372G, 375I, 389L, 393S, 397P, 400G, 404I, 452Q, 455G, 456W, 459S, 463Y, 464S, 467A, 480T, 481V, 484M, 485S, 488G, 489S, 492S
CDD
cd06174 (MFS)

393S

putative substrate translocation pore
134Q, 137I, 138N, 139N, 141Y, 142V, 160T, 163Y, 164T, 167T, 171Q, 172I, 174M, 175M, 221E, 222S, 225Y, 226P, 229H, 230Y, 233G, 245A, 246G, 249Y, 250F, 256L, 364A, 367S, 368N, 371S, 372G, 375I, 389L, 393S, 397P, 400G, 404I, 452Q, 455G, 456W, 459S, 463Y, 464S, 467A, 480T, 481V, 484M, 485S, 488G, 489S, 492S
CDD
cd06174 (MFS)

397P

putative substrate translocation pore
134Q, 137I, 138N, 139N, 141Y, 142V, 160T, 163Y, 164T, 167T, 171Q, 172I, 174M, 175M, 221E, 222S, 225Y, 226P, 229H, 230Y, 233G, 245A, 246G, 249Y, 250F, 256L, 364A, 367S, 368N, 371S, 372G, 375I, 389L, 393S, 397P, 400G, 404I, 452Q, 455G, 456W, 459S, 463Y, 464S, 467A, 480T, 481V, 484M, 485S, 488G, 489S, 492S
CDD
cd06174 (MFS)

400G

putative substrate translocation pore
134Q, 137I, 138N, 139N, 141Y, 142V, 160T, 163Y, 164T, 167T, 171Q, 172I, 174M, 175M, 221E, 222S, 225Y, 226P, 229H, 230Y, 233G, 245A, 246G, 249Y, 250F, 256L, 364A, 367S, 368N, 371S, 372G, 375I, 389L, 393S, 397P, 400G, 404I, 452Q, 455G, 456W, 459S, 463Y, 464S, 467A, 480T, 481V, 484M, 485S, 488G, 489S, 492S
CDD
cd06174 (MFS)

404I

putative substrate translocation pore
134Q, 137I, 138N, 139N, 141Y, 142V, 160T, 163Y, 164T, 167T, 171Q, 172I, 174M, 175M, 221E, 222S, 225Y, 226P, 229H, 230Y, 233G, 245A, 246G, 249Y, 250F, 256L, 364A, 367S, 368N, 371S, 372G, 375I, 389L, 393S, 397P, 400G, 404I, 452Q, 455G, 456W, 459S, 463Y, 464S, 467A, 480T, 481V, 484M, 485S, 488G, 489S, 492S
CDD
cd06174 (MFS)

452Q

putative substrate translocation pore
134Q, 137I, 138N, 139N, 141Y, 142V, 160T, 163Y, 164T, 167T, 171Q, 172I, 174M, 175M, 221E, 222S, 225Y, 226P, 229H, 230Y, 233G, 245A, 246G, 249Y, 250F, 256L, 364A, 367S, 368N, 371S, 372G, 375I, 389L, 393S, 397P, 400G, 404I, 452Q, 455G, 456W, 459S, 463Y, 464S, 467A, 480T, 481V, 484M, 485S, 488G, 489S, 492S
CDD
cd06174 (MFS)

455G

putative substrate translocation pore
134Q, 137I, 138N, 139N, 141Y, 142V, 160T, 163Y, 164T, 167T, 171Q, 172I, 174M, 175M, 221E, 222S, 225Y, 226P, 229H, 230Y, 233G, 245A, 246G, 249Y, 250F, 256L, 364A, 367S, 368N, 371S, 372G, 375I, 389L, 393S, 397P, 400G, 404I, 452Q, 455G, 456W, 459S, 463Y, 464S, 467A, 480T, 481V, 484M, 485S, 488G, 489S, 492S
CDD
cd06174 (MFS)

456W

putative substrate translocation pore
134Q, 137I, 138N, 139N, 141Y, 142V, 160T, 163Y, 164T, 167T, 171Q, 172I, 174M, 175M, 221E, 222S, 225Y, 226P, 229H, 230Y, 233G, 245A, 246G, 249Y, 250F, 256L, 364A, 367S, 368N, 371S, 372G, 375I, 389L, 393S, 397P, 400G, 404I, 452Q, 455G, 456W, 459S, 463Y, 464S, 467A, 480T, 481V, 484M, 485S, 488G, 489S, 492S
CDD
cd06174 (MFS)

459S

putative substrate translocation pore
134Q, 137I, 138N, 139N, 141Y, 142V, 160T, 163Y, 164T, 167T, 171Q, 172I, 174M, 175M, 221E, 222S, 225Y, 226P, 229H, 230Y, 233G, 245A, 246G, 249Y, 250F, 256L, 364A, 367S, 368N, 371S, 372G, 375I, 389L, 393S, 397P, 400G, 404I, 452Q, 455G, 456W, 459S, 463Y, 464S, 467A, 480T, 481V, 484M, 485S, 488G, 489S, 492S
CDD
cd06174 (MFS)

463Y

putative substrate translocation pore
134Q, 137I, 138N, 139N, 141Y, 142V, 160T, 163Y, 164T, 167T, 171Q, 172I, 174M, 175M, 221E, 222S, 225Y, 226P, 229H, 230Y, 233G, 245A, 246G, 249Y, 250F, 256L, 364A, 367S, 368N, 371S, 372G, 375I, 389L, 393S, 397P, 400G, 404I, 452Q, 455G, 456W, 459S, 463Y, 464S, 467A, 480T, 481V, 484M, 485S, 488G, 489S, 492S
CDD
cd06174 (MFS)

464S

putative substrate translocation pore
134Q, 137I, 138N, 139N, 141Y, 142V, 160T, 163Y, 164T, 167T, 171Q, 172I, 174M, 175M, 221E, 222S, 225Y, 226P, 229H, 230Y, 233G, 245A, 246G, 249Y, 250F, 256L, 364A, 367S, 368N, 371S, 372G, 375I, 389L, 393S, 397P, 400G, 404I, 452Q, 455G, 456W, 459S, 463Y, 464S, 467A, 480T, 481V, 484M, 485S, 488G, 489S, 492S
CDD
cd06174 (MFS)

467A

putative substrate translocation pore
134Q, 137I, 138N, 139N, 141Y, 142V, 160T, 163Y, 164T, 167T, 171Q, 172I, 174M, 175M, 221E, 222S, 225Y, 226P, 229H, 230Y, 233G, 245A, 246G, 249Y, 250F, 256L, 364A, 367S, 368N, 371S, 372G, 375I, 389L, 393S, 397P, 400G, 404I, 452Q, 455G, 456W, 459S, 463Y, 464S, 467A, 480T, 481V, 484M, 485S, 488G, 489S, 492S
CDD
cd06174 (MFS)

480T

putative substrate translocation pore
134Q, 137I, 138N, 139N, 141Y, 142V, 160T, 163Y, 164T, 167T, 171Q, 172I, 174M, 175M, 221E, 222S, 225Y, 226P, 229H, 230Y, 233G, 245A, 246G, 249Y, 250F, 256L, 364A, 367S, 368N, 371S, 372G, 375I, 389L, 393S, 397P, 400G, 404I, 452Q, 455G, 456W, 459S, 463Y, 464S, 467A, 480T, 481V, 484M, 485S, 488G, 489S, 492S
CDD
cd06174 (MFS)

481V

putative substrate translocation pore
134Q, 137I, 138N, 139N, 141Y, 142V, 160T, 163Y, 164T, 167T, 171Q, 172I, 174M, 175M, 221E, 222S, 225Y, 226P, 229H, 230Y, 233G, 245A, 246G, 249Y, 250F, 256L, 364A, 367S, 368N, 371S, 372G, 375I, 389L, 393S, 397P, 400G, 404I, 452Q, 455G, 456W, 459S, 463Y, 464S, 467A, 480T, 481V, 484M, 485S, 488G, 489S, 492S
CDD
cd06174 (MFS)

484M

putative substrate translocation pore
134Q, 137I, 138N, 139N, 141Y, 142V, 160T, 163Y, 164T, 167T, 171Q, 172I, 174M, 175M, 221E, 222S, 225Y, 226P, 229H, 230Y, 233G, 245A, 246G, 249Y, 250F, 256L, 364A, 367S, 368N, 371S, 372G, 375I, 389L, 393S, 397P, 400G, 404I, 452Q, 455G, 456W, 459S, 463Y, 464S, 467A, 480T, 481V, 484M, 485S, 488G, 489S, 492S
CDD
cd06174 (MFS)

485S

putative substrate translocation pore
134Q, 137I, 138N, 139N, 141Y, 142V, 160T, 163Y, 164T, 167T, 171Q, 172I, 174M, 175M, 221E, 222S, 225Y, 226P, 229H, 230Y, 233G, 245A, 246G, 249Y, 250F, 256L, 364A, 367S, 368N, 371S, 372G, 375I, 389L, 393S, 397P, 400G, 404I, 452Q, 455G, 456W, 459S, 463Y, 464S, 467A, 480T, 481V, 484M, 485S, 488G, 489S, 492S
CDD
cd06174 (MFS)

488G

putative substrate translocation pore
134Q, 137I, 138N, 139N, 141Y, 142V, 160T, 163Y, 164T, 167T, 171Q, 172I, 174M, 175M, 221E, 222S, 225Y, 226P, 229H, 230Y, 233G, 245A, 246G, 249Y, 250F, 256L, 364A, 367S, 368N, 371S, 372G, 375I, 389L, 393S, 397P, 400G, 404I, 452Q, 455G, 456W, 459S, 463Y, 464S, 467A, 480T, 481V, 484M, 485S, 488G, 489S, 492S
CDD
cd06174 (MFS)

489S

putative substrate translocation pore
134Q, 137I, 138N, 139N, 141Y, 142V, 160T, 163Y, 164T, 167T, 171Q, 172I, 174M, 175M, 221E, 222S, 225Y, 226P, 229H, 230Y, 233G, 245A, 246G, 249Y, 250F, 256L, 364A, 367S, 368N, 371S, 372G, 375I, 389L, 393S, 397P, 400G, 404I, 452Q, 455G, 456W, 459S, 463Y, 464S, 467A, 480T, 481V, 484M, 485S, 488G, 489S, 492S
CDD
cd06174 (MFS)

492S

putative substrate translocation pore
134Q, 137I, 138N, 139N, 141Y, 142V, 160T, 163Y, 164T, 167T, 171Q, 172I, 174M, 175M, 221E, 222S, 225Y, 226P, 229H, 230Y, 233G, 245A, 246G, 249Y, 250F, 256L, 364A, 367S, 368N, 371S, 372G, 375I, 389L, 393S, 397P, 400G, 404I, 452Q, 455G, 456W, 459S, 463Y, 464S, 467A, 480T, 481V, 484M, 485S, 488G, 489S, 492S
CDD
cd06174 (MFS)

Protein sequence

>MIA_00423_1
MKIISIIRQFIPHYRDINEGLFINKEHSTIETISQPDGSETVVATKETWKVNEQEQIESPNEIQYEIRDEANRKWWSMFN
EYEYKSREESRSNNKWYHWFNESDSPKERRLIMKLDLILCLFSFTMYWVKYLDQSNINNAYVSGMKEDLKMKGNDLINTT
SLYTVGTILFQIPMMFLIHRYPTHIILPVMDLGWGFFTLAIYRSNTLGELKGYRFFVGVFESAFYPTIHYLLGSWYKPSE
YARRAGVFYFGKMLGLCTAGLIMSSCVRLDGVHGIAGWRWMFIIDAIITMPIAVIGFFVIPGTPHKCYSIILTDEDIFVA
RKRLRDANISIESEGPKFFSVDLWKKMFSNWKWYMFVLLNILVANCSNTSSGSFILWLKSLNKYSISRLNELSSVTPALG
IVWIFLVTSFSDQFRSRWGAIFISQFFNFFCNILLAVWNIPYALKWFAFCLQCFGWAASSVLYSWAADAMRHDPQERAIT
VVTMSLIGSASSAGLNVLVWKTSEAPRFFKGYVFTCAVAVSMVLVATIILPLYKKDERKHAKENGILLYNSAKGEVPPTP
PS

GO term prediction

Biological Process

GO:0055085 transmembrane transport

Molecular Function

None predicted.

Cellular Component

GO:0016021 integral component of membrane

Filter view on

Entry type

Status

Per-residue features