MCA_02572_1

Protein

Length

599 amino acids

Gene name: SEO1A

Description: Probable transporter SEO1

Browser: contigB:1687792-1689667+

RNA-seq: read pairs 56, FPKM 1.2, percentile rank 9.7% (100% = highest expression)

Protein function

Annotation:		SEO1A	Probable transporter SEO1
EGGNOG:	0PFST	FG03636.1	MFS transporter (Seo1)
SGD closest match:	S000000062	SEO1	Probable transporter SEO1
CGD closest match:	CAL0000175721	CAALFM_CR06790CA	Uncharacterized protein

Protein alignments

	%id	Aln length	E-value
MIA_00277_1	66.79%	551	0.0	MIA_00277_1
UniRef50_F2QQK0	59.67%	543	0.0	Biotin symporter n=11 Tax=Saccharomycetales TaxID=4892 RepID=F2QQK0_KOMPC
A0A0J9XCA2_GEOCN	58.75%	543	0.0	Similar to Saccharomyces cerevisiae YAL067C SEO1 Putative permease OS=Geotrichum candidum GN=BN980_GECA09s00208g PE=4 SV=1
A0A060SWU6_BLAAD	61.87%	493	0.0	ARAD1A08228p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A08228g PE=4 SV=1
A0A1E3PMS6_9ASCO	58.10%	494	0.0	MFS general substrate transporter OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_46126 PE=4 SV=1
Q6C1T2_YARLI	52.39%	523	0.0	YALI0F13607p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F13607g PE=4 SV=1
SEO1_YEAST	53.02%	496	0.0	Probable transporter SEO1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SEO1 PE=1 SV=1
Q59MT5_CANAL	49.36%	543	0.0	Uncharacterized protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CAALFM_CR06790CA PE=4 SV=1
A0A161HL86_9ASCO	28.21%	521	8e-68	Putative permease SEO1 OS=Sugiyamaella lignohabitans GN=SEO1 PE=4 SV=1
A0A1E4TD78_9ASCO	24.22%	483	2e-29	Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_142936 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9706
Predicted cleavage: 25

Protein family membership

Major facilitator superfamily (IPR011701)

Domains and repeats

Domain
114 - 551
Major facilitator superfamily domain (IPR020846)

1 100 200 300 400 500 599

Detailed signature matches

IPR011701

Major facilitator superfamily
1. PF07690 (MFS_1)
  
  136 - 497
  
  Pfam
  PF07690 (MFS_1)
IPR020846

Major facilitator superfamily domain
1. SSF103473 (MFS gene...)
  
  114 - 551
  
  SUPERFAMILY
  SSF103473 (MFS general substrate transporter)
2. cd06174 (MFS)
  
  132 - 542
  
  CDD
  cd06174 (MFS)

no IPR

Unintegrated signatures

CYTOPLASMIC_D... (C...)

547 - 599

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

425 - 430

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

31 - 122

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

480 - 490

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

314 - 365

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

248 - 258

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

191 - 196

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)
G3DSA:1.20.12...

350 - 560

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)

121 - 322

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)
NON_CYTOPLASM... (N...)

452 - 456

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

216 - 226

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

280 - 290

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

1 - 11

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

514 - 524

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

142 - 172

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

391 - 401

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)
TMhelix

168 - 190

TMHMM
TMhelix (TMhelix)

524 - 546

TMHMM
TMhelix (TMhelix)

431 - 453

TMHMM
TMhelix (TMhelix)

257 - 279

TMHMM
TMhelix (TMhelix)

123 - 141

TMHMM
TMhelix (TMhelix)

457 - 479

TMHMM
TMhelix (TMhelix)

294 - 316

TMHMM
TMhelix (TMhelix)

405 - 424

TMHMM
TMhelix (TMhelix)

223 - 245

TMHMM
TMhelix (TMhelix)

368 - 390

TMHMM
TMhelix (TMhelix)

491 - 513

TMHMM
TMhelix (TMhelix)

197 - 219

TMHMM
TMhelix (TMhelix)
TRANSMEMBRANE (Tran...)

259 - 279

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

366 - 390

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

227 - 247

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

402 - 424

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

457 - 479

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

525 - 546

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

123 - 141

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

431 - 451

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

291 - 313

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

12 - 30

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

197 - 215

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

173 - 190

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

491 - 513

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

Residue annotation

putative substrate...

146Q

putative substrate translocation pore
146Q, 149L, 150N, 151N, 153Y, 154V, 172Q, 175Y, 176T, 179S, 183Q, 184I, 186C, 187M, 233E, 234S, 237Y, 238P, 241H, 242Y, 245G, 257G, 258G, 261Y, 262F, 268I, 374V, 377Y, 378N, 381N, 382G, 385G, 402V, 406S, 410P, 413G, 417I, 465Q, 468G, 469W, 472S, 476Y, 477S, 480S, 493T, 494V, 497M, 498N, 501G, 502Q, 505Q
CDD
cd06174 (MFS)

149L

putative substrate translocation pore
146Q, 149L, 150N, 151N, 153Y, 154V, 172Q, 175Y, 176T, 179S, 183Q, 184I, 186C, 187M, 233E, 234S, 237Y, 238P, 241H, 242Y, 245G, 257G, 258G, 261Y, 262F, 268I, 374V, 377Y, 378N, 381N, 382G, 385G, 402V, 406S, 410P, 413G, 417I, 465Q, 468G, 469W, 472S, 476Y, 477S, 480S, 493T, 494V, 497M, 498N, 501G, 502Q, 505Q
CDD
cd06174 (MFS)

150N

putative substrate translocation pore
146Q, 149L, 150N, 151N, 153Y, 154V, 172Q, 175Y, 176T, 179S, 183Q, 184I, 186C, 187M, 233E, 234S, 237Y, 238P, 241H, 242Y, 245G, 257G, 258G, 261Y, 262F, 268I, 374V, 377Y, 378N, 381N, 382G, 385G, 402V, 406S, 410P, 413G, 417I, 465Q, 468G, 469W, 472S, 476Y, 477S, 480S, 493T, 494V, 497M, 498N, 501G, 502Q, 505Q
CDD
cd06174 (MFS)

151N

putative substrate translocation pore
146Q, 149L, 150N, 151N, 153Y, 154V, 172Q, 175Y, 176T, 179S, 183Q, 184I, 186C, 187M, 233E, 234S, 237Y, 238P, 241H, 242Y, 245G, 257G, 258G, 261Y, 262F, 268I, 374V, 377Y, 378N, 381N, 382G, 385G, 402V, 406S, 410P, 413G, 417I, 465Q, 468G, 469W, 472S, 476Y, 477S, 480S, 493T, 494V, 497M, 498N, 501G, 502Q, 505Q
CDD
cd06174 (MFS)

153Y

putative substrate translocation pore
146Q, 149L, 150N, 151N, 153Y, 154V, 172Q, 175Y, 176T, 179S, 183Q, 184I, 186C, 187M, 233E, 234S, 237Y, 238P, 241H, 242Y, 245G, 257G, 258G, 261Y, 262F, 268I, 374V, 377Y, 378N, 381N, 382G, 385G, 402V, 406S, 410P, 413G, 417I, 465Q, 468G, 469W, 472S, 476Y, 477S, 480S, 493T, 494V, 497M, 498N, 501G, 502Q, 505Q
CDD
cd06174 (MFS)

154V

putative substrate translocation pore
146Q, 149L, 150N, 151N, 153Y, 154V, 172Q, 175Y, 176T, 179S, 183Q, 184I, 186C, 187M, 233E, 234S, 237Y, 238P, 241H, 242Y, 245G, 257G, 258G, 261Y, 262F, 268I, 374V, 377Y, 378N, 381N, 382G, 385G, 402V, 406S, 410P, 413G, 417I, 465Q, 468G, 469W, 472S, 476Y, 477S, 480S, 493T, 494V, 497M, 498N, 501G, 502Q, 505Q
CDD
cd06174 (MFS)

172Q

putative substrate translocation pore
146Q, 149L, 150N, 151N, 153Y, 154V, 172Q, 175Y, 176T, 179S, 183Q, 184I, 186C, 187M, 233E, 234S, 237Y, 238P, 241H, 242Y, 245G, 257G, 258G, 261Y, 262F, 268I, 374V, 377Y, 378N, 381N, 382G, 385G, 402V, 406S, 410P, 413G, 417I, 465Q, 468G, 469W, 472S, 476Y, 477S, 480S, 493T, 494V, 497M, 498N, 501G, 502Q, 505Q
CDD
cd06174 (MFS)

175Y

putative substrate translocation pore
146Q, 149L, 150N, 151N, 153Y, 154V, 172Q, 175Y, 176T, 179S, 183Q, 184I, 186C, 187M, 233E, 234S, 237Y, 238P, 241H, 242Y, 245G, 257G, 258G, 261Y, 262F, 268I, 374V, 377Y, 378N, 381N, 382G, 385G, 402V, 406S, 410P, 413G, 417I, 465Q, 468G, 469W, 472S, 476Y, 477S, 480S, 493T, 494V, 497M, 498N, 501G, 502Q, 505Q
CDD
cd06174 (MFS)

176T

putative substrate translocation pore
146Q, 149L, 150N, 151N, 153Y, 154V, 172Q, 175Y, 176T, 179S, 183Q, 184I, 186C, 187M, 233E, 234S, 237Y, 238P, 241H, 242Y, 245G, 257G, 258G, 261Y, 262F, 268I, 374V, 377Y, 378N, 381N, 382G, 385G, 402V, 406S, 410P, 413G, 417I, 465Q, 468G, 469W, 472S, 476Y, 477S, 480S, 493T, 494V, 497M, 498N, 501G, 502Q, 505Q
CDD
cd06174 (MFS)

179S

putative substrate translocation pore
146Q, 149L, 150N, 151N, 153Y, 154V, 172Q, 175Y, 176T, 179S, 183Q, 184I, 186C, 187M, 233E, 234S, 237Y, 238P, 241H, 242Y, 245G, 257G, 258G, 261Y, 262F, 268I, 374V, 377Y, 378N, 381N, 382G, 385G, 402V, 406S, 410P, 413G, 417I, 465Q, 468G, 469W, 472S, 476Y, 477S, 480S, 493T, 494V, 497M, 498N, 501G, 502Q, 505Q
CDD
cd06174 (MFS)

183Q

putative substrate translocation pore
146Q, 149L, 150N, 151N, 153Y, 154V, 172Q, 175Y, 176T, 179S, 183Q, 184I, 186C, 187M, 233E, 234S, 237Y, 238P, 241H, 242Y, 245G, 257G, 258G, 261Y, 262F, 268I, 374V, 377Y, 378N, 381N, 382G, 385G, 402V, 406S, 410P, 413G, 417I, 465Q, 468G, 469W, 472S, 476Y, 477S, 480S, 493T, 494V, 497M, 498N, 501G, 502Q, 505Q
CDD
cd06174 (MFS)

184I

putative substrate translocation pore
146Q, 149L, 150N, 151N, 153Y, 154V, 172Q, 175Y, 176T, 179S, 183Q, 184I, 186C, 187M, 233E, 234S, 237Y, 238P, 241H, 242Y, 245G, 257G, 258G, 261Y, 262F, 268I, 374V, 377Y, 378N, 381N, 382G, 385G, 402V, 406S, 410P, 413G, 417I, 465Q, 468G, 469W, 472S, 476Y, 477S, 480S, 493T, 494V, 497M, 498N, 501G, 502Q, 505Q
CDD
cd06174 (MFS)

186C

putative substrate translocation pore
146Q, 149L, 150N, 151N, 153Y, 154V, 172Q, 175Y, 176T, 179S, 183Q, 184I, 186C, 187M, 233E, 234S, 237Y, 238P, 241H, 242Y, 245G, 257G, 258G, 261Y, 262F, 268I, 374V, 377Y, 378N, 381N, 382G, 385G, 402V, 406S, 410P, 413G, 417I, 465Q, 468G, 469W, 472S, 476Y, 477S, 480S, 493T, 494V, 497M, 498N, 501G, 502Q, 505Q
CDD
cd06174 (MFS)

187M

putative substrate translocation pore
146Q, 149L, 150N, 151N, 153Y, 154V, 172Q, 175Y, 176T, 179S, 183Q, 184I, 186C, 187M, 233E, 234S, 237Y, 238P, 241H, 242Y, 245G, 257G, 258G, 261Y, 262F, 268I, 374V, 377Y, 378N, 381N, 382G, 385G, 402V, 406S, 410P, 413G, 417I, 465Q, 468G, 469W, 472S, 476Y, 477S, 480S, 493T, 494V, 497M, 498N, 501G, 502Q, 505Q
CDD
cd06174 (MFS)

233E

putative substrate translocation pore
146Q, 149L, 150N, 151N, 153Y, 154V, 172Q, 175Y, 176T, 179S, 183Q, 184I, 186C, 187M, 233E, 234S, 237Y, 238P, 241H, 242Y, 245G, 257G, 258G, 261Y, 262F, 268I, 374V, 377Y, 378N, 381N, 382G, 385G, 402V, 406S, 410P, 413G, 417I, 465Q, 468G, 469W, 472S, 476Y, 477S, 480S, 493T, 494V, 497M, 498N, 501G, 502Q, 505Q
CDD
cd06174 (MFS)

234S

putative substrate translocation pore
146Q, 149L, 150N, 151N, 153Y, 154V, 172Q, 175Y, 176T, 179S, 183Q, 184I, 186C, 187M, 233E, 234S, 237Y, 238P, 241H, 242Y, 245G, 257G, 258G, 261Y, 262F, 268I, 374V, 377Y, 378N, 381N, 382G, 385G, 402V, 406S, 410P, 413G, 417I, 465Q, 468G, 469W, 472S, 476Y, 477S, 480S, 493T, 494V, 497M, 498N, 501G, 502Q, 505Q
CDD
cd06174 (MFS)

237Y

putative substrate translocation pore
146Q, 149L, 150N, 151N, 153Y, 154V, 172Q, 175Y, 176T, 179S, 183Q, 184I, 186C, 187M, 233E, 234S, 237Y, 238P, 241H, 242Y, 245G, 257G, 258G, 261Y, 262F, 268I, 374V, 377Y, 378N, 381N, 382G, 385G, 402V, 406S, 410P, 413G, 417I, 465Q, 468G, 469W, 472S, 476Y, 477S, 480S, 493T, 494V, 497M, 498N, 501G, 502Q, 505Q
CDD
cd06174 (MFS)

238P

putative substrate translocation pore
146Q, 149L, 150N, 151N, 153Y, 154V, 172Q, 175Y, 176T, 179S, 183Q, 184I, 186C, 187M, 233E, 234S, 237Y, 238P, 241H, 242Y, 245G, 257G, 258G, 261Y, 262F, 268I, 374V, 377Y, 378N, 381N, 382G, 385G, 402V, 406S, 410P, 413G, 417I, 465Q, 468G, 469W, 472S, 476Y, 477S, 480S, 493T, 494V, 497M, 498N, 501G, 502Q, 505Q
CDD
cd06174 (MFS)

241H

putative substrate translocation pore
146Q, 149L, 150N, 151N, 153Y, 154V, 172Q, 175Y, 176T, 179S, 183Q, 184I, 186C, 187M, 233E, 234S, 237Y, 238P, 241H, 242Y, 245G, 257G, 258G, 261Y, 262F, 268I, 374V, 377Y, 378N, 381N, 382G, 385G, 402V, 406S, 410P, 413G, 417I, 465Q, 468G, 469W, 472S, 476Y, 477S, 480S, 493T, 494V, 497M, 498N, 501G, 502Q, 505Q
CDD
cd06174 (MFS)

242Y

putative substrate translocation pore
146Q, 149L, 150N, 151N, 153Y, 154V, 172Q, 175Y, 176T, 179S, 183Q, 184I, 186C, 187M, 233E, 234S, 237Y, 238P, 241H, 242Y, 245G, 257G, 258G, 261Y, 262F, 268I, 374V, 377Y, 378N, 381N, 382G, 385G, 402V, 406S, 410P, 413G, 417I, 465Q, 468G, 469W, 472S, 476Y, 477S, 480S, 493T, 494V, 497M, 498N, 501G, 502Q, 505Q
CDD
cd06174 (MFS)

245G

putative substrate translocation pore
146Q, 149L, 150N, 151N, 153Y, 154V, 172Q, 175Y, 176T, 179S, 183Q, 184I, 186C, 187M, 233E, 234S, 237Y, 238P, 241H, 242Y, 245G, 257G, 258G, 261Y, 262F, 268I, 374V, 377Y, 378N, 381N, 382G, 385G, 402V, 406S, 410P, 413G, 417I, 465Q, 468G, 469W, 472S, 476Y, 477S, 480S, 493T, 494V, 497M, 498N, 501G, 502Q, 505Q
CDD
cd06174 (MFS)

257G

putative substrate translocation pore
146Q, 149L, 150N, 151N, 153Y, 154V, 172Q, 175Y, 176T, 179S, 183Q, 184I, 186C, 187M, 233E, 234S, 237Y, 238P, 241H, 242Y, 245G, 257G, 258G, 261Y, 262F, 268I, 374V, 377Y, 378N, 381N, 382G, 385G, 402V, 406S, 410P, 413G, 417I, 465Q, 468G, 469W, 472S, 476Y, 477S, 480S, 493T, 494V, 497M, 498N, 501G, 502Q, 505Q
CDD
cd06174 (MFS)

258G

putative substrate translocation pore
146Q, 149L, 150N, 151N, 153Y, 154V, 172Q, 175Y, 176T, 179S, 183Q, 184I, 186C, 187M, 233E, 234S, 237Y, 238P, 241H, 242Y, 245G, 257G, 258G, 261Y, 262F, 268I, 374V, 377Y, 378N, 381N, 382G, 385G, 402V, 406S, 410P, 413G, 417I, 465Q, 468G, 469W, 472S, 476Y, 477S, 480S, 493T, 494V, 497M, 498N, 501G, 502Q, 505Q
CDD
cd06174 (MFS)

261Y

putative substrate translocation pore
146Q, 149L, 150N, 151N, 153Y, 154V, 172Q, 175Y, 176T, 179S, 183Q, 184I, 186C, 187M, 233E, 234S, 237Y, 238P, 241H, 242Y, 245G, 257G, 258G, 261Y, 262F, 268I, 374V, 377Y, 378N, 381N, 382G, 385G, 402V, 406S, 410P, 413G, 417I, 465Q, 468G, 469W, 472S, 476Y, 477S, 480S, 493T, 494V, 497M, 498N, 501G, 502Q, 505Q
CDD
cd06174 (MFS)

262F

putative substrate translocation pore
146Q, 149L, 150N, 151N, 153Y, 154V, 172Q, 175Y, 176T, 179S, 183Q, 184I, 186C, 187M, 233E, 234S, 237Y, 238P, 241H, 242Y, 245G, 257G, 258G, 261Y, 262F, 268I, 374V, 377Y, 378N, 381N, 382G, 385G, 402V, 406S, 410P, 413G, 417I, 465Q, 468G, 469W, 472S, 476Y, 477S, 480S, 493T, 494V, 497M, 498N, 501G, 502Q, 505Q
CDD
cd06174 (MFS)

268I

putative substrate translocation pore
146Q, 149L, 150N, 151N, 153Y, 154V, 172Q, 175Y, 176T, 179S, 183Q, 184I, 186C, 187M, 233E, 234S, 237Y, 238P, 241H, 242Y, 245G, 257G, 258G, 261Y, 262F, 268I, 374V, 377Y, 378N, 381N, 382G, 385G, 402V, 406S, 410P, 413G, 417I, 465Q, 468G, 469W, 472S, 476Y, 477S, 480S, 493T, 494V, 497M, 498N, 501G, 502Q, 505Q
CDD
cd06174 (MFS)

374V

putative substrate translocation pore
146Q, 149L, 150N, 151N, 153Y, 154V, 172Q, 175Y, 176T, 179S, 183Q, 184I, 186C, 187M, 233E, 234S, 237Y, 238P, 241H, 242Y, 245G, 257G, 258G, 261Y, 262F, 268I, 374V, 377Y, 378N, 381N, 382G, 385G, 402V, 406S, 410P, 413G, 417I, 465Q, 468G, 469W, 472S, 476Y, 477S, 480S, 493T, 494V, 497M, 498N, 501G, 502Q, 505Q
CDD
cd06174 (MFS)

377Y

putative substrate translocation pore
146Q, 149L, 150N, 151N, 153Y, 154V, 172Q, 175Y, 176T, 179S, 183Q, 184I, 186C, 187M, 233E, 234S, 237Y, 238P, 241H, 242Y, 245G, 257G, 258G, 261Y, 262F, 268I, 374V, 377Y, 378N, 381N, 382G, 385G, 402V, 406S, 410P, 413G, 417I, 465Q, 468G, 469W, 472S, 476Y, 477S, 480S, 493T, 494V, 497M, 498N, 501G, 502Q, 505Q
CDD
cd06174 (MFS)

378N

putative substrate translocation pore
146Q, 149L, 150N, 151N, 153Y, 154V, 172Q, 175Y, 176T, 179S, 183Q, 184I, 186C, 187M, 233E, 234S, 237Y, 238P, 241H, 242Y, 245G, 257G, 258G, 261Y, 262F, 268I, 374V, 377Y, 378N, 381N, 382G, 385G, 402V, 406S, 410P, 413G, 417I, 465Q, 468G, 469W, 472S, 476Y, 477S, 480S, 493T, 494V, 497M, 498N, 501G, 502Q, 505Q
CDD
cd06174 (MFS)

381N

putative substrate translocation pore
146Q, 149L, 150N, 151N, 153Y, 154V, 172Q, 175Y, 176T, 179S, 183Q, 184I, 186C, 187M, 233E, 234S, 237Y, 238P, 241H, 242Y, 245G, 257G, 258G, 261Y, 262F, 268I, 374V, 377Y, 378N, 381N, 382G, 385G, 402V, 406S, 410P, 413G, 417I, 465Q, 468G, 469W, 472S, 476Y, 477S, 480S, 493T, 494V, 497M, 498N, 501G, 502Q, 505Q
CDD
cd06174 (MFS)

382G

putative substrate translocation pore
146Q, 149L, 150N, 151N, 153Y, 154V, 172Q, 175Y, 176T, 179S, 183Q, 184I, 186C, 187M, 233E, 234S, 237Y, 238P, 241H, 242Y, 245G, 257G, 258G, 261Y, 262F, 268I, 374V, 377Y, 378N, 381N, 382G, 385G, 402V, 406S, 410P, 413G, 417I, 465Q, 468G, 469W, 472S, 476Y, 477S, 480S, 493T, 494V, 497M, 498N, 501G, 502Q, 505Q
CDD
cd06174 (MFS)

385G

putative substrate translocation pore
146Q, 149L, 150N, 151N, 153Y, 154V, 172Q, 175Y, 176T, 179S, 183Q, 184I, 186C, 187M, 233E, 234S, 237Y, 238P, 241H, 242Y, 245G, 257G, 258G, 261Y, 262F, 268I, 374V, 377Y, 378N, 381N, 382G, 385G, 402V, 406S, 410P, 413G, 417I, 465Q, 468G, 469W, 472S, 476Y, 477S, 480S, 493T, 494V, 497M, 498N, 501G, 502Q, 505Q
CDD
cd06174 (MFS)

402V

putative substrate translocation pore
146Q, 149L, 150N, 151N, 153Y, 154V, 172Q, 175Y, 176T, 179S, 183Q, 184I, 186C, 187M, 233E, 234S, 237Y, 238P, 241H, 242Y, 245G, 257G, 258G, 261Y, 262F, 268I, 374V, 377Y, 378N, 381N, 382G, 385G, 402V, 406S, 410P, 413G, 417I, 465Q, 468G, 469W, 472S, 476Y, 477S, 480S, 493T, 494V, 497M, 498N, 501G, 502Q, 505Q
CDD
cd06174 (MFS)

406S

putative substrate translocation pore
146Q, 149L, 150N, 151N, 153Y, 154V, 172Q, 175Y, 176T, 179S, 183Q, 184I, 186C, 187M, 233E, 234S, 237Y, 238P, 241H, 242Y, 245G, 257G, 258G, 261Y, 262F, 268I, 374V, 377Y, 378N, 381N, 382G, 385G, 402V, 406S, 410P, 413G, 417I, 465Q, 468G, 469W, 472S, 476Y, 477S, 480S, 493T, 494V, 497M, 498N, 501G, 502Q, 505Q
CDD
cd06174 (MFS)

410P

putative substrate translocation pore
146Q, 149L, 150N, 151N, 153Y, 154V, 172Q, 175Y, 176T, 179S, 183Q, 184I, 186C, 187M, 233E, 234S, 237Y, 238P, 241H, 242Y, 245G, 257G, 258G, 261Y, 262F, 268I, 374V, 377Y, 378N, 381N, 382G, 385G, 402V, 406S, 410P, 413G, 417I, 465Q, 468G, 469W, 472S, 476Y, 477S, 480S, 493T, 494V, 497M, 498N, 501G, 502Q, 505Q
CDD
cd06174 (MFS)

413G

putative substrate translocation pore
146Q, 149L, 150N, 151N, 153Y, 154V, 172Q, 175Y, 176T, 179S, 183Q, 184I, 186C, 187M, 233E, 234S, 237Y, 238P, 241H, 242Y, 245G, 257G, 258G, 261Y, 262F, 268I, 374V, 377Y, 378N, 381N, 382G, 385G, 402V, 406S, 410P, 413G, 417I, 465Q, 468G, 469W, 472S, 476Y, 477S, 480S, 493T, 494V, 497M, 498N, 501G, 502Q, 505Q
CDD
cd06174 (MFS)

417I

putative substrate translocation pore
146Q, 149L, 150N, 151N, 153Y, 154V, 172Q, 175Y, 176T, 179S, 183Q, 184I, 186C, 187M, 233E, 234S, 237Y, 238P, 241H, 242Y, 245G, 257G, 258G, 261Y, 262F, 268I, 374V, 377Y, 378N, 381N, 382G, 385G, 402V, 406S, 410P, 413G, 417I, 465Q, 468G, 469W, 472S, 476Y, 477S, 480S, 493T, 494V, 497M, 498N, 501G, 502Q, 505Q
CDD
cd06174 (MFS)

465Q

putative substrate translocation pore
146Q, 149L, 150N, 151N, 153Y, 154V, 172Q, 175Y, 176T, 179S, 183Q, 184I, 186C, 187M, 233E, 234S, 237Y, 238P, 241H, 242Y, 245G, 257G, 258G, 261Y, 262F, 268I, 374V, 377Y, 378N, 381N, 382G, 385G, 402V, 406S, 410P, 413G, 417I, 465Q, 468G, 469W, 472S, 476Y, 477S, 480S, 493T, 494V, 497M, 498N, 501G, 502Q, 505Q
CDD
cd06174 (MFS)

468G

putative substrate translocation pore
146Q, 149L, 150N, 151N, 153Y, 154V, 172Q, 175Y, 176T, 179S, 183Q, 184I, 186C, 187M, 233E, 234S, 237Y, 238P, 241H, 242Y, 245G, 257G, 258G, 261Y, 262F, 268I, 374V, 377Y, 378N, 381N, 382G, 385G, 402V, 406S, 410P, 413G, 417I, 465Q, 468G, 469W, 472S, 476Y, 477S, 480S, 493T, 494V, 497M, 498N, 501G, 502Q, 505Q
CDD
cd06174 (MFS)

469W

putative substrate translocation pore
146Q, 149L, 150N, 151N, 153Y, 154V, 172Q, 175Y, 176T, 179S, 183Q, 184I, 186C, 187M, 233E, 234S, 237Y, 238P, 241H, 242Y, 245G, 257G, 258G, 261Y, 262F, 268I, 374V, 377Y, 378N, 381N, 382G, 385G, 402V, 406S, 410P, 413G, 417I, 465Q, 468G, 469W, 472S, 476Y, 477S, 480S, 493T, 494V, 497M, 498N, 501G, 502Q, 505Q
CDD
cd06174 (MFS)

472S

putative substrate translocation pore
146Q, 149L, 150N, 151N, 153Y, 154V, 172Q, 175Y, 176T, 179S, 183Q, 184I, 186C, 187M, 233E, 234S, 237Y, 238P, 241H, 242Y, 245G, 257G, 258G, 261Y, 262F, 268I, 374V, 377Y, 378N, 381N, 382G, 385G, 402V, 406S, 410P, 413G, 417I, 465Q, 468G, 469W, 472S, 476Y, 477S, 480S, 493T, 494V, 497M, 498N, 501G, 502Q, 505Q
CDD
cd06174 (MFS)

476Y

putative substrate translocation pore
146Q, 149L, 150N, 151N, 153Y, 154V, 172Q, 175Y, 176T, 179S, 183Q, 184I, 186C, 187M, 233E, 234S, 237Y, 238P, 241H, 242Y, 245G, 257G, 258G, 261Y, 262F, 268I, 374V, 377Y, 378N, 381N, 382G, 385G, 402V, 406S, 410P, 413G, 417I, 465Q, 468G, 469W, 472S, 476Y, 477S, 480S, 493T, 494V, 497M, 498N, 501G, 502Q, 505Q
CDD
cd06174 (MFS)

477S

putative substrate translocation pore
146Q, 149L, 150N, 151N, 153Y, 154V, 172Q, 175Y, 176T, 179S, 183Q, 184I, 186C, 187M, 233E, 234S, 237Y, 238P, 241H, 242Y, 245G, 257G, 258G, 261Y, 262F, 268I, 374V, 377Y, 378N, 381N, 382G, 385G, 402V, 406S, 410P, 413G, 417I, 465Q, 468G, 469W, 472S, 476Y, 477S, 480S, 493T, 494V, 497M, 498N, 501G, 502Q, 505Q
CDD
cd06174 (MFS)

480S

putative substrate translocation pore
146Q, 149L, 150N, 151N, 153Y, 154V, 172Q, 175Y, 176T, 179S, 183Q, 184I, 186C, 187M, 233E, 234S, 237Y, 238P, 241H, 242Y, 245G, 257G, 258G, 261Y, 262F, 268I, 374V, 377Y, 378N, 381N, 382G, 385G, 402V, 406S, 410P, 413G, 417I, 465Q, 468G, 469W, 472S, 476Y, 477S, 480S, 493T, 494V, 497M, 498N, 501G, 502Q, 505Q
CDD
cd06174 (MFS)

493T

putative substrate translocation pore
146Q, 149L, 150N, 151N, 153Y, 154V, 172Q, 175Y, 176T, 179S, 183Q, 184I, 186C, 187M, 233E, 234S, 237Y, 238P, 241H, 242Y, 245G, 257G, 258G, 261Y, 262F, 268I, 374V, 377Y, 378N, 381N, 382G, 385G, 402V, 406S, 410P, 413G, 417I, 465Q, 468G, 469W, 472S, 476Y, 477S, 480S, 493T, 494V, 497M, 498N, 501G, 502Q, 505Q
CDD
cd06174 (MFS)

494V

putative substrate translocation pore
146Q, 149L, 150N, 151N, 153Y, 154V, 172Q, 175Y, 176T, 179S, 183Q, 184I, 186C, 187M, 233E, 234S, 237Y, 238P, 241H, 242Y, 245G, 257G, 258G, 261Y, 262F, 268I, 374V, 377Y, 378N, 381N, 382G, 385G, 402V, 406S, 410P, 413G, 417I, 465Q, 468G, 469W, 472S, 476Y, 477S, 480S, 493T, 494V, 497M, 498N, 501G, 502Q, 505Q
CDD
cd06174 (MFS)

497M

putative substrate translocation pore
146Q, 149L, 150N, 151N, 153Y, 154V, 172Q, 175Y, 176T, 179S, 183Q, 184I, 186C, 187M, 233E, 234S, 237Y, 238P, 241H, 242Y, 245G, 257G, 258G, 261Y, 262F, 268I, 374V, 377Y, 378N, 381N, 382G, 385G, 402V, 406S, 410P, 413G, 417I, 465Q, 468G, 469W, 472S, 476Y, 477S, 480S, 493T, 494V, 497M, 498N, 501G, 502Q, 505Q
CDD
cd06174 (MFS)

498N

putative substrate translocation pore
146Q, 149L, 150N, 151N, 153Y, 154V, 172Q, 175Y, 176T, 179S, 183Q, 184I, 186C, 187M, 233E, 234S, 237Y, 238P, 241H, 242Y, 245G, 257G, 258G, 261Y, 262F, 268I, 374V, 377Y, 378N, 381N, 382G, 385G, 402V, 406S, 410P, 413G, 417I, 465Q, 468G, 469W, 472S, 476Y, 477S, 480S, 493T, 494V, 497M, 498N, 501G, 502Q, 505Q
CDD
cd06174 (MFS)

501G

putative substrate translocation pore
146Q, 149L, 150N, 151N, 153Y, 154V, 172Q, 175Y, 176T, 179S, 183Q, 184I, 186C, 187M, 233E, 234S, 237Y, 238P, 241H, 242Y, 245G, 257G, 258G, 261Y, 262F, 268I, 374V, 377Y, 378N, 381N, 382G, 385G, 402V, 406S, 410P, 413G, 417I, 465Q, 468G, 469W, 472S, 476Y, 477S, 480S, 493T, 494V, 497M, 498N, 501G, 502Q, 505Q
CDD
cd06174 (MFS)

502Q

putative substrate translocation pore
146Q, 149L, 150N, 151N, 153Y, 154V, 172Q, 175Y, 176T, 179S, 183Q, 184I, 186C, 187M, 233E, 234S, 237Y, 238P, 241H, 242Y, 245G, 257G, 258G, 261Y, 262F, 268I, 374V, 377Y, 378N, 381N, 382G, 385G, 402V, 406S, 410P, 413G, 417I, 465Q, 468G, 469W, 472S, 476Y, 477S, 480S, 493T, 494V, 497M, 498N, 501G, 502Q, 505Q
CDD
cd06174 (MFS)

505Q

putative substrate translocation pore
146Q, 149L, 150N, 151N, 153Y, 154V, 172Q, 175Y, 176T, 179S, 183Q, 184I, 186C, 187M, 233E, 234S, 237Y, 238P, 241H, 242Y, 245G, 257G, 258G, 261Y, 262F, 268I, 374V, 377Y, 378N, 381N, 382G, 385G, 402V, 406S, 410P, 413G, 417I, 465Q, 468G, 469W, 472S, 476Y, 477S, 480S, 493T, 494V, 497M, 498N, 501G, 502Q, 505Q
CDD
cd06174 (MFS)

Protein sequence

>MCA_02572_1
MSSAILQKTKIAYNRFIAFWHRLFLAFLALKFIPKLREIDEELCAKRLAEKQKLRLAAKGKSDIPEKEITPLKEPQWEIR
DEANRKWWSVFNEYEYKYNTDKQSDHKWYHWFEETDTVEEKRLIAKLDILLCFYAFVMYWVKYLDQSNLNNAYVSGMKEH
LGMKGNDLVNTQAVYTVGSVIFQIPCMYLIHRYPAHLILPVMDIGWGLFTLAIYRANSVGELQAYRFFVGVFESAFYPTI
HYLFGSWYKPSEYSRRGGIYYFGQMLGILTAGLLQSSTYENLNGRNGILGYQWQFIIDAVITLPVGIIGFFSLPGVPKKC
YSLFLTDEDIYVARERLRKADIKLENEGPNFFSLALWKKILSSWKWYVFTFYNVFAYNASNGTSGAYLLWLKSLGKYSIP
KVNQYSAITPALGIVWIFLTGVVADNFRTRFGAVIFSQTFNMLGNILLAVWNIPEGAIWFAFCLQYFGWAISPAMYSWAS
DATRHNPQERAITVVSMNMVGQAMQAWTSVLVWKTVEAPRYLKGFSFTAANAFGLMVWSALILPLYKKDERRHAAENKIL
IYNSANGEVPPAIPAEDPKDIAKVEDTWESTQEIKSNRS

GO term prediction

Biological Process

GO:0055085 transmembrane transport

Molecular Function

None predicted.

Cellular Component

GO:0016021 integral component of membrane

Filter view on

Entry type

Status

Per-residue features