Protein

MIA_00408_1

Length
1,102 amino acids

Browser: contig01:1168678-1171987-

Protein function

EGGNOG:0PH3NAMS1alpha-mannosidase
SGD closest match:S000003124AMS1Alpha-mannosidase
CGD closest match:CAL0000179816AMS1Alpha-mannosidase

Protein alignments

%idAln lengthE-value
MCA_01153_173.85%11280.0MCA_01153_1
A0A0J9XFS7_GEOCN63.80%11160.0Alpha-mannosidase OS=Geotrichum candidum GN=BN980_GECA12s01522g PE=3 SV=1
A0A167C741_9ASCO59.14%11330.0Alpha-mannosidase OS=Sugiyamaella lignohabitans GN=AMS1 PE=3 SV=1
UniRef50_A0A167C74159.14%11330.0Alpha-mannosidase n=7 Tax=saccharomyceta TaxID=716545 RepID=A0A167C741_9ASCO
A0A1E3PRI3_9ASCO57.55%11330.0Alpha-mannosidase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_19326 PE=3 SV=1
A0A060T462_BLAAD56.51%11130.0Alpha-mannosidase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C41866g PE=3 SV=1
Q6C883_YARLI53.69%11250.0Alpha-mannosidase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D21890g PE=3 SV=1
A0A1E4TDL9_9ASCO54.36%10670.0Alpha-mannosidase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_96681 PE=3 SV=1
Q5AF38_CANAL44.49%11620.0Alpha-mannosidase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=AMS1 PE=3 SV=1
MAN1_YEAST45.61%11270.0Alpha-mannosidase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=AMS1 PE=1 SV=2

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.5361

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 200 400 600 800 1000 1102

Detailed signature matches

  1. Domain IPR011330
    Glycoside hydrolase/deacetylase, beta/alpha-barrel
    1. SSF88713 (Glycoside...)
  2. Domain IPR027291
    Glycoside hydrolase 38/57, N-terminal domain
    1. G3DSA:3.20.11...
  3. Domain IPR000602
    Glycoside hydrolase family 38, N-terminal domain
    1. PF01074 (Glyco_hydr...)
  4. Domain IPR028995
    Glycoside hydrolase families 57/38, central domain
    1. SSF88688 (Families ...)
  5. Domain IPR015341
    Glycoside hydrolase family 38, central domain
    1. SM00872 (Alpha_mann...)
    2. PF09261 (Alpha-mann...)
    3. G3DSA:1.20.12...
  6. Domain IPR011013
    Galactose mutarotase-like domain
    1. SSF74650 (Galactose...)
  7. Domain IPR011682
    Glycosyl hydrolase family 38, C-terminal
    1. PF07748 (Glyco_hydr...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:2.60.40...
  2. cd10812 (GH38N_AMII...)

Residue annotation

  1. active site cd10812
  2. catalytic site cd1...

Protein sequence

>MIA_00408_1
MGKYPLRNTAPVFKKVQSIYENRLRLFTSDGEYKTLNLPNFYDRKTVSGSPHLTLEVYSVPNSARPLFKDVVPTAKWRPT
ERGESFGPSWSTHWFRIEITVPSEWADEEQVIFKWDAGNEGCIYHEDGTIVVGLSGAERKEWIVPSEWQKDGKKHLFYIE
MACNGMFGNGTPDDIHPPDNNRWFTLSTVELLVPNLEARALYIDFWIIGDAARELPDDSWQKHKAREVANLIMDTFSPAR
PDETIAECRKISKEYVGKLVDSSKVYKSPLAAEVTAIGNCHIDTAWLWPYAETRRKVARSWSSQLDLLERYPEYVFAASQ
AQQMEWLLQDHPELFKRVQDAVKEGRFIPVGGSWVENDTNMPTGEAIVRQFLLGQRFFEEHFGHRSRTFWLPDTFGYSAQ
IPQLCRGAEMDRFLTQKLSWNNINKFPNTTFNWVALDGSQVICHMPPDDTYTAAAHFGDVARSLKQNKNMDVDHHGMLLY
GHGDGGGGPTAEMLEKLRRCRGVSDTVGMLPRVNSGTTVDEFYDSIAESTKNGKELVTWIGELYFEFHRGTYTSQSDTKK
HNRRSEIILHDLEFYATLASLSNKSYSYPKKDIDELWKDVCLNQFHDVLPGSSIEMVYDDVKIIYADVYKRAHKLTNEAL
EALGLSDVPKSSNAEFVAVNTMPWPRFEVIEVPAPVESAAVQSNDDTHLVLVSSDVGSEVATPVSQADFEAFSTSEATAQ
EIAPNVFLLENGLLRATIDGGHLTSLYDIKHNRELIVKGDAGNKLVILEDQPLYWQAWDTELYSLDTRHELEKGTGTITK
SGPLRAEIEVSQKISEKSSIVTRISLDAVGAPPDADIVDGSLLRFDCSVEWHEECKFLKVEFPVDIVNDTASYETQFGIV
KRPTHFNTSWDVAKFEVCAHKWGDFSEYSHGITLLNDCKYGYSIHGQVIRLSLLRAPKAPDAHADMGHHTFTYALLPHEG
GVSHHIVRAGYNLNHPLKGLYRDTSTVTPSAVLGAVQVKGEPGLVLSTIKRFEDDAEVAYGGLPVRSKKPSAIVRIYEAL
GGRARGKLVLDGKLLPAVTKAFKTNLLEDDEEELEVTVNSSGDSEISLELGSFQVGSFRVEF

GO term prediction

Biological Process

GO:0005975 carbohydrate metabolic process
GO:0006013 mannose metabolic process

Molecular Function

GO:0003824 catalytic activity
GO:0004559 alpha-mannosidase activity
GO:0030246 carbohydrate binding

Cellular Component

None predicted.