Protein

MCA_01153_1

Length
1,117 amino acids

Gene name: AMS1

Description: Alpha-mannosidase

Browser: contigA:3656444-3659798-

RNA-seq: read pairs 3899, FPKM 43.1, percentile rank 62.1% (100% = highest expression)

Protein function

Annotation:AMS1Alpha-mannosidase
KEGG:K01191E3.2.1.24 alpha-mannosidase [EC:3.2.1.24]
EGGNOG:0PH3NAMS1alpha-mannosidase
SGD closest match:S000003124AMS1Alpha-mannosidase
CGD closest match:CAL0000179816AMS1Alpha-mannosidase

Protein alignments

%idAln lengthE-value
MIA_00408_173.85%11280.0MIA_00408_1
A0A0J9XFS7_GEOCN61.83%11240.0Alpha-mannosidase OS=Geotrichum candidum GN=BN980_GECA12s01522g PE=3 SV=1
A0A167C741_9ASCO57.17%11300.0Alpha-mannosidase OS=Sugiyamaella lignohabitans GN=AMS1 PE=3 SV=1
UniRef50_A0A167C74157.17%11300.0Alpha-mannosidase n=7 Tax=saccharomyceta TaxID=716545 RepID=A0A167C741_9ASCO
A0A1E3PRI3_9ASCO58.36%11430.0Alpha-mannosidase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_19326 PE=3 SV=1
A0A060T462_BLAAD56.31%10620.0Alpha-mannosidase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C41866g PE=3 SV=1
Q6C883_YARLI52.58%11260.0Alpha-mannosidase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D21890g PE=3 SV=1
A0A1E4TDL9_9ASCO52.53%10680.0Alpha-mannosidase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_96681 PE=3 SV=1
MAN1_YEAST46.09%11370.0Alpha-mannosidase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=AMS1 PE=1 SV=2
Q5AF38_CANAL44.60%11390.0Alpha-mannosidase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=AMS1 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.6110

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 200 400 600 800 1000 1117

Detailed signature matches

  1. Domain IPR011330
    Glycoside hydrolase/deacetylase, beta/alpha-barrel
    1. SSF88713 (Glycoside...)
  2. Domain IPR027291
    Glycoside hydrolase 38/57, N-terminal domain
    1. G3DSA:3.20.11...
  3. Domain IPR000602
    Glycoside hydrolase family 38, N-terminal domain
    1. PF01074 (Glyco_hydr...)
  4. Domain IPR028995
    Glycoside hydrolase families 57/38, central domain
    1. SSF88688 (Families ...)
  5. Domain IPR015341
    Glycoside hydrolase family 38, central domain
    1. SM00872 (Alpha_mann...)
    2. G3DSA:1.20.12...
    3. PF09261 (Alpha-mann...)
  6. Domain IPR011013
    Galactose mutarotase-like domain
    1. SSF74650 (Galactose...)
  7. Domain IPR011682
    Glycosyl hydrolase family 38, C-terminal
    1. PF07748 (Glyco_hydr...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. cd10812 (GH38N_AMII...)

Residue annotation

  1. active site cd10812
  2. catalytic site cd1...

Protein sequence

>MCA_01153_1
MGKYSLRNTKPVFKKVQSIYESRLRQFTSDGQYVEFNIPSFYDKKKESSKEHISLEVYSVPDTERPLFKDVVPVAKWRPT
ERGESFGPSWTTHWFRINITVPKEWADEEQVIFKWDAGNEGMIYHEDGTIVVGLSGAERKEWILPKEWNDGKSHLFYIEM
SCNGMFGNGTPEDIFPPDNKRFFELKTVELIVPNLEARALHIDFWIISDAARELPDDSWQKHKAREVATVIMDTFDAQNP
DETIAKCRAIAQEFVGKLVNSSKVYDSPQHSEVIAIGNCHIDTAWLWPYAETRRKIARSWASQLDLLERYPEYVFAASQA
QQFQWLLEDHPKLFKRIQDAVKEGRFIPVGGSWVENDTNMPTGEAIVRQFLLGQRFFEEHFGMRSRTFWLPDTFGYSAQI
PQLCRGAEMDRFLTQKLSWNNINRFPNTTFNWVALDGSQVICHMPPDDTYTALANFGDVMRSLKQHKNMDVNHSGMLLYG
HGDGGGGPTAEMLEKLRRCRGMSDTVGMLPRVHSGPSVDEFYDDIEKSTNNGEDLVTWVGELYFEFHRGTYTSQSDTKKH
NRRSEIILHDLEFYSTLASLVNSDYKYPKKDIDDLWKDVCLNQFHDVLPGSSIEMVYDDVKIIYHDIYKRAQELTKSAFK
ALGLDDTPEIYNGTQELVAINTMPWGRTEVVEADASIVPLNASHHQQLITSEEGSKALVIMHSDDTGLASPVTTESNVGS
VSVKKVADNVYEMENEVLRVKVDGGHVTSLYDIKHDRELIPEGQAGNRFVLFNDEPLYWQAWDTELYSLDTFKEVGKGEV
KISKAGPLRAELEVCHKISEESSIVSKISLDVFTGDRLGSNAGTTLVSQLKFECEVEWHENCKFLKVEFPVDIVCDTASY
ETQFGLVKRPTHFNTSWDVAKFEVCGHKWADLSEYSHGVALLNDCKYGYSIHGQVMRLSLLRSPKAPDAHADMGHHSFVY
SVIPHEGGVNHEIVQAGYNLNHPLKTLYKDEETFGAAVVGKGKEVVSAIRAKGDAGLVLSTIKRFEDDAEVHYGGLPVRS
KKASVIVRIYESLGGKARGHILVDERALNGKTVGKVFKTNLLEDDIEEIEIKKENKEVQIPVQLGAFEVGTIRIEFN

GO term prediction

Biological Process

GO:0005975 carbohydrate metabolic process
GO:0006013 mannose metabolic process

Molecular Function

GO:0003824 catalytic activity
GO:0004559 alpha-mannosidase activity
GO:0030246 carbohydrate binding

Cellular Component

None predicted.