Protein

MIA_00406_1

Length
484 amino acids

Browser: contig01:1164769-1166415-

Protein function

EGGNOG:0PFRALAG1Longevity-assurance protein
SGD closest match:S000000995LAG1Sphingosine N-acyltransferase LAG1
CGD closest match:CAL0000190688LAC1Lac1p

Protein alignments

%idAln lengthE-value
MCA_01151_157.632%3211.07e-127MCA_01151_1
A0A0J9XAI5_GEOCN46.053%3801.38e-115Similar to Saccharomyces cerevisiae YKL008C LAC1 Ceramide synthase component OS=Geotrichum candidum GN=BN980_GECA07s02111g PE=4 SV=1
UniRef50_A0A0J9XAI546.053%3802.83e-112Similar to Saccharomyces cerevisiae YKL008C LAC1 Ceramide synthase component n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XAI5_GEOCN
A0A060T784_BLAAD48.634%3661.07e-113ARAD1B21472p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B21472g PE=4 SV=1
A0A167CI24_9ASCO48.169%3551.28e-112Sphingosine N-acyltransferase LAG1 OS=Sugiyamaella lignohabitans GN=LAG1 PE=4 SV=1
A0A1E3PPQ1_9ASCO48.624%3279.27e-99Longevity assurance proteins LAG1/LAC1 (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_5022 PE=4 SV=1
F2Z5Z1_YARLI46.647%3439.95e-98YALI0D04026p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D04026g PE=4 SV=1
A0A1D8PKA5_CANAL41.944%3601.75e-86Lac1p OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=LAC1 PE=4 SV=1
A0A1E4TBF5_9ASCO38.017%3631.99e-78Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_133693 PE=4 SV=1
LAG1_YEAST31.003%3293.90e-35Sphingosine N-acyltransferase LAG1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=LAG1 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0535

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 400 450 484

Detailed signature matches

  1. Family IPR016439
    Ceramide synthase component Lag1/Lac1
    1. PIRSF005225 (LAG1_LAC1)
  2. Domain IPR013599
    TRAM1-like protein
    1. PF08390 (TRAM1)
  3. Domain IPR006634
    TRAM/LAG1/CLN8 homology domain
    1. PS50922 (TLC)
    2. PF03798 (TRAM_LAG1_...)
    3. SM00724 (lag1_27)
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. Coil
  3. NON_CYTOPLASM... (N...)
  4. TMhelix
  5. TRANSMEMBRANE (Tran...)
  6. mobidb-lite (disord...)

Protein sequence

>MIA_00406_1
MATLLHNGPGSPIVPSTSHQIDHDIAIAGTDQESPASSALSSSVPSSSSSSASSPPASPRSANGDSPLATPLQSLPTDSS
TALPLPQKPTEDVFAEPFAPSLISKRSTLTTDSQTPNYNNDNTQKPTTPQAPPLRNARGPASRGGISEYIHKRQLKVSLF
LIAFVILSHLFVPSFRSFTSKCLLLSYVNTRPDGSVYASIGPNDVYLVSFWIVVLTFSRALFVDNWLLRMARHVFGIKSN
KITTRFAEQSYALMTYGTFFGWGAILISHSPYLTSVQELWRGWPHHEMSLAMKAYYLVQLASWLQQIYVINIEERRKDHY
QMFTHHIVTCALIIGSYYYYFTRVGHVILVLMDAVDITLSLAKVLRYTGFQRACDATFVVFLISWLLLRHGLYNYILYSA
YTDVPRLLPPKCYYDEITGEQIRCFTKSAYYTFVGLLAILQGITIIWLYMIIRVLIRMLLGDSAADSRSDEDTDAELEES
KKEK

GO term prediction

Biological Process

None predicted.

Molecular Function

None predicted.

Cellular Component

GO:0005783 endoplasmic reticulum
GO:0016021 integral component of membrane