Protein

MIA_00400_1

Length
1,944 amino acids


Browser: contig01:1143707-1149632+

Protein function

EGGNOG:0PHZCSEPARINK02365 separase EC 3.4.22.49
SGD closest match:S000003330ESP1Separin
CGD closest match:CAL0000192671ESP1Separase

Protein alignments

%idAln lengthE-value
MCA_00428_142.595%19040.0MCA_00428_1
A0A0J9XJN5_GEOCN44.444%15030.0Similar to Saccharomyces cerevisiae YGR098C ESP1 Separase, a caspase-like cysteine protease OS=Geotrichum candidum GN=BN980_GECA19s01924g PE=4 SV=1
UniRef50_A0A0J9XJN544.444%15030.0Similar to Saccharomyces cerevisiae YGR098C ESP1 Separase, a caspase-like cysteine protease n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XJN5_GEOCN
A0A167C907_9ASCO32.866%14970.0Esp1p OS=Sugiyamaella lignohabitans GN=ESP1 PE=4 SV=1
A0A1E3PS02_9ASCO27.468%19043.72e-178Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_39597 PE=4 SV=1
A0A060T006_BLAAD37.366%7445.19e-151ARAD1C08888p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C08888g PE=4 SV=1
Q6CCJ0_YARLI36.040%7024.82e-118YALI0C08960p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C08960g PE=4 SV=1
ESP1_YEAST37.931%5226.16e-93Separin OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ESP1 PE=1 SV=2
A0A1E4TM90_9ASCO30.087%6884.34e-68Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_93747 PE=4 SV=1
A0A1D8PCM0_CANAL33.942%2745.66e-41Separase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ESP1 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.3733

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 200 400 600 800 1000 1200 1400 1600 1800 1944

Detailed signature matches

    1. SSF48452 (TPR-like)
    1. PS51700 (SEPARIN)
Unintegrated signatures no IPR
Unintegrated signatures
  1. PF03568 (Peptidase_C50)

Protein sequence

>MIA_00400_1
MNEVSLPDISNLSFDRLLRIKSILQPSKNTRIHDTSVANRKNNVQQALISTDRKLIRSKTASERHKLALHIINSADNVIE
SWNEKKTSIRKLSTSSLPSPSPSPPPLDSTKIAAYEAISLAFKTLYENRSANSAKQLDLEKRHLSIILKLLDVPMIDESI
LELHVLVDNINLRIHGSLLPFASIFTISPNPNYLNQSTANLIVYTQIAILKSIIKVPPASQPVSNKTIIDSLNSPNGILF
WVSQIPLNAATQKLVIFAKLFLALSNNCDSLTCFSYRIASLQLFPQIQEVYVNMLLASYSTLRKKENMSYDNIIQDYGTD
LIRLVKKKYMQLKTFSTFVTWFDRLSKKSSSNIWNEANNLIKNVNVDPVLSLVEELKLDPTVEKMNALSSIENIQEYFGA
PEFFNTFLHVSKTFLDASQYLNFIGIIDFYLFFLHTKHPNLTKSFSKVSSSFFHHVKVIIEKDVSDSTFIVLLSIYEKIA
NGLEIIEDNTHLMYISNSLLPIGARLRHKNNDIYLEYWNKSVSIELDLFEKTSHPSLSFPGKLERLIITLIDFAKLNEAF
RILCLSFPLIASLEKIQDSASTLPLYLQWQSPSSNRLLNIFASVLLEDSTCKDIEIKNVGAEIEGSILEQLLICLEKYTG
STKKETAIQIMKRLEVLYFNNPLRLLRSYNFFFKSVNEIYNIQVMEELLENLVIKSTLTNNNRRTSNGANLLVDSSKLKS
DIELAHHRFFIISCASFSLAISSATVSTKKYQFFNCSVNYAIEMFKSKTQSDNTEKVISHIQSMCAFLDLQGANEKRADL
LKAMRDSFLLKGESNEVLVNRMHCRLDLINSLIALGYTGSAVKEISSLESEYQDHQFIVPIDRAWVKLRHAQSLVSVGDT
VTARTVFKSLFEMIQNDELLKMPLLKGRPATEERHHFQQRSLLFAEICITLGLLHSAEGNVDYGISQAQKSISFLQGFLK
KFQSSSGNRSSRETTWQLTSILINAQIQMAMSYERLGIIREACYYVDEAIKTAQASDCGLRLAVILAFEAEVRVKMGNHT
KSTECLEKCQSIIEKLNLQDLNVLYYAHSAILSLQRQRLFNEENQYYVLSDKIFSDLEQKSHKFSVSEMAKKISRLSLTN
MEAVTPKSTTITMSTRRSLVGRRLSGPLYSEKSTPTPTFRKSLPSTSPMNFLPMMDTPKKDRIIKEESQEGPSEIFGVEI
IWNSIVRSQVYSLGLQNSVDGAMSLLEDQYRSVSIRDDLLLEIAQARNLFLLAKNILSKDPVYSFVFDSVICVPSIKPNH
AFRDNYMNDSTLPKSAINHLEKALKMILDNIPKIMILCNATEVSSVASLLNAVQMSLAAILEIIYEKIDIGKVATSYANL
VLQDASRRLTLESDRSVVKLRSSDYNWPTEAPERVDTPKTIISMYNDFEHDILNSLPEKWAAVSISVSAETGSLSLCRYE
KNKIPLQLCLPLNRHSSRDANEESFSFDLGMQRLREIIEKSNASASSQRTSQIKTSEERHLWWKERYSLDQKLEELLGDV
EYFWLGGFKGMFSRERVVSHLLENLATQFVKLLRVYLPSRNWVSGGVRPRSGLGKSRSREEFQRFSGSLQENNNGSTGST
CKGSAGLEEVEIELDPRVLELFVGLGDPDNIKDPGLIEDLTYFVLDILQFHGERNAFDEIEIDQLMVHLETALHHYHAQV
ASMDEQLREGDVEHTVLVLDRNTQAFPWESIPCLREQSVSRVPSLSILSQLLKEHYQPEIDPVWPVVQVSLEKSSSDSGC
YYILNPSRDLPKTQERFESKLTNLRGWSGLVSEEPTESKLVEMLETGNLVIYIGHGSGLQYIRAAKIKSLKRCCATLLLG
CSSGALEEAGDYDPWGTPMTYMIAGCPMLLANMWDVTDKDIDLFSTCMLERWGVLPPPNPGMGASAISEAVRDSRDDCNL
RFLNGAAPVIYGIPLKIKKTVEKK

GO term prediction

Biological Process

GO:0006508 proteolysis

Molecular Function

GO:0005515 protein binding
GO:0008233 peptidase activity

Cellular Component

None predicted.