Protein

MIA_00399_1

Length
539 amino acids

Browser: contig01:1141373-1143338-

Protein function

EGGNOG:0PFCPNOG2Nucleolar GTP-binding protein
SGD closest match:S000005336NOG2Nucleolar GTP-binding protein 2
CGD closest match:CAL0000182741NOG2Nucleolar GTP-binding protein 2

Protein alignments

%idAln lengthE-value
MCA_00427_184.13%4600.0MCA_00427_1
A0A0J9XIQ9_GEOCN77.88%4430.0Nucleolar GTP-binding protein 2 OS=Geotrichum candidum GN=BN980_GECA19s01946g PE=3 SV=1
A0A1E3PS89_9ASCO75.62%4430.0Nucleolar GTP-binding protein 2 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_68480 PE=3 SV=1
NOG2_YARLI76.24%4420.0Nucleolar GTP-binding protein 2 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=NOG2 PE=3 SV=1
UniRef50_Q75DA474.33%4480.0Nucleolar GTP-binding protein 2 n=53 Tax=Eukaryota TaxID=2759 RepID=NOG2_ASHGO
A0A1D8PQ82_CANAL71.30%4600.0Nucleolar GTP-binding protein 2 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=NOG2 PE=3 SV=1
A0A060T5X0_BLAAD72.40%4420.0Nucleolar GTP-binding protein 2 OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C08844g PE=3 SV=1
NOG2_YEAST70.63%4460.0Nucleolar GTP-binding protein 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NOG2 PE=1 SV=1
A0A1E4TL71_9ASCO65.16%4420.0Nucleolar GTP-binding protein 2 OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_87541 PE=3 SV=1
A0A167F3F6_9ASCO62.45%2611e-113Nucleolar GTP-binding protein 2 OS=Sugiyamaella lignohabitans GN=NOG2 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0318

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 50 100 150 200 250 300 350 400 450 500 539

Detailed signature matches

  1. Domain IPR012971
    Nucleolar GTP-binding protein 2, N-terminal domain
    1. PF08153 (NGP1NT)
  2. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
  3. Domain IPR030378
    Circularly permuted (CP)-type guanine nucleotide-binding (G) domain
    1. PS51721 (G_CP)
  4. Domain IPR006073
    GTP binding domain
    1. PF01926 (MMR_HSR1)
    2. PR00326 (GTP1OBG)
  5. Domain IPR023179
    GTP-binding protein, orthogonal bundle domain
    1. G3DSA:1.10.15...
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:1.20.12...
  3. cd01858 (NGP_1)
  4. mobidb-lite (disord...)

Residue annotation

  1. G4 box cd01858
  2. GTP/Mg2+ binding s...
  3. G5 box cd01858
  4. G1 box cd01858
  5. Switch I region cd...
  6. G2 box cd01858
  7. G3 box cd01858
  8. Switch II region c...

Protein sequence

>MIA_00399_1
MGAHKREKKASKPAASSSGSSEPKRPGNLKVKGENFFRDAKKVKRLNMYKEGRAKHNARGDVVREATFQSTEIPNARIAP
DRRWFNSTRVISQDALINFREAMKDKKDDPYQVILRKNKLPMSLLEEKTHVPTVKIVETESYEHTFGPKSQRKKPNLTVS
SLEELATHADDSLKRYEDKLEEDAENAAHLEEGWSNQAKEAIFHKGTSKRIWNELYKVIDSSDVIIHVLDARDPIGTRCI
SVQDYLKKEAPHKHLIYVLNKCDLVPNWVTAAWIKHLSKSYPTIAFHASITNSFGKGSLISLLRQFSSLHADRKQISVGF
IGYPNVGKSSIINTLRKKKVCNVAPIPGETKIWQYITLMKRIFLIDCPGIVPPSSKDTETDILFKGVVRVEHVSNPEQFI
PAMLSRCKQHHLENTYEIRGWQDSTQFLEMIARKSGRLLKGGEPDESGVAKMVLNDFNRGKIPWFVPPPMDEDKEAKEGE
KAGSSSLNDREGKLGEKRKRKSEDADKPAKKTKADEKDEDDEEEAEDSNDDNDNDSNDE

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0005525 GTP binding

Cellular Component

None predicted.