Protein

MCA_00427_1

Length
549 amino acids

Gene name: NOG2

Description: Nucleolar GTP-binding protein 2

Browser: contigA:1345733-1347768-

RNA-seq: read pairs 2665, FPKM 59.9, percentile rank 69.2% (100% = highest expression)

Protein function

Annotation:NOG2Nucleolar GTP-binding protein 2
KEGG:K14537NUG2 nuclear GTP-binding protein
EGGNOG:0PFCPNOG2Nucleolar GTP-binding protein
SGD closest match:S000005336NOG2Nucleolar GTP-binding protein 2
CGD closest match:CAL0000182741NOG2Nucleolar GTP-binding protein 2

Protein alignments

%idAln lengthE-value
MIA_00399_177.92%5300.0MIA_00399_1
A0A0J9XIQ9_GEOCN72.48%4870.0Nucleolar GTP-binding protein 2 OS=Geotrichum candidum GN=BN980_GECA19s01946g PE=3 SV=1
UniRef50_A0A1E3NZR167.81%4970.0Nucleolar GTP-binding protein 2 n=4 Tax=Opisthokonta TaxID=33154 RepID=A0A1E3NZR1_WICAO
A0A1E3PS89_9ASCO72.14%4630.0Nucleolar GTP-binding protein 2 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_68480 PE=3 SV=1
A0A1D8PQ82_CANAL66.47%5100.0Nucleolar GTP-binding protein 2 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=NOG2 PE=3 SV=1
NOG2_YARLI65.46%5270.0Nucleolar GTP-binding protein 2 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=NOG2 PE=3 SV=1
A0A060T5X0_BLAAD68.10%4890.0Nucleolar GTP-binding protein 2 OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C08844g PE=3 SV=1
NOG2_YEAST66.40%4910.0Nucleolar GTP-binding protein 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NOG2 PE=1 SV=1
A0A1E4TL71_9ASCO60.93%4940.0Nucleolar GTP-binding protein 2 OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_87541 PE=3 SV=1
A0A167F3F6_9ASCO53.09%3072e-101Nucleolar GTP-binding protein 2 OS=Sugiyamaella lignohabitans GN=NOG2 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0823

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 50 100 150 200 250 300 350 400 450 500 549

Detailed signature matches

  1. Domain IPR012971
    Nucleolar GTP-binding protein 2, N-terminal domain
    1. PF08153 (NGP1NT)
  2. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
  3. Domain IPR030378
    Circularly permuted (CP)-type guanine nucleotide-binding (G) domain
    1. PS51721 (G_CP)
  4. Domain IPR006073
    GTP binding domain
    1. PF01926 (MMR_HSR1)
    2. PR00326 (GTP1OBG)
  5. Domain IPR023179
    GTP-binding protein, orthogonal bundle domain
    1. G3DSA:1.10.15...
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:1.20.12...
  3. cd01858 (NGP_1)
  4. mobidb-lite (disord...)

Residue annotation

  1. G4 box cd01858
  2. GTP/Mg2+ binding s...
  3. G5 box cd01858
  4. G1 box cd01858
  5. Switch I region cd...
  6. G2 box cd01858
  7. G3 box cd01858
  8. Switch II region c...

Protein sequence

>MCA_00427_1
MGVHKREKKKATTSTKSGLAPTTDPNRPGNLKLKGENFFRDAAKVKRLNMYKEGRATRNARGDIVKAATFQSTEVPTARV
QPDRRWFNSTRVISQDALIAFREAMKEKKDDPYQFILKKNKLPMSLLEENDANLIEDDEEDGEGKKRRRKHPTVKILETE
SFEHTFGPKAQRKKARLAVSSLEELAQETEDSLKKYEDKVGEDVDEGLEEGWSNLAKEAIFHKGQSKRIWNELYKVIDSS
DVLIHVLDARDPLGTQCLSVQEYLKKEAPHKHLVYVLNKCDLVPNWVTAAWIKHLSKSYPTIAFHASITNSFGKGSLISL
LRQFSSLHSDRKQISVGFIGYPNVGKSSIINTLRKKKVCTVAPIPGETKIWQYITLMKRIFLIDCPGIVPPSSKDTETDI
LFRGVVRVEHVSNPEQFIPAMLERCKRHHLENTYEVKGWEDATQFLEMIARKSGRLLKGGEPDESGVAKMVLNDFNRGKI
PWFVPPPEDANRKNATEEEEVDDDESTKKAPGSLKDRTGKLGEMRKKRPTKEEIEEEDDIISNDEDESD

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0005525 GTP binding

Cellular Component

None predicted.