Protein
MIA_00334_1
Length
566 amino acids
Browser: contig01:961537-963238-
Protein function
| EGGNOG: | 0PKSX | ALG10 | Adds the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(2)Man(9)GlcNAc(2)-PP-Dol |
|---|---|---|---|
| SGD closest match: | S000003459 | DIE2 | Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase |
| CGD closest match: | CAL0000181033 | DIE2 | Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MCA_01091_1 | 37.412% | 425 | 6.46e-73 | MCA_01091_1 |
| A0A0J9XBG7_GEOCN | 34.596% | 581 | 2.48e-70 | Similar to Saccharomyces cerevisiae YGR227W DIE2 Dolichyl-phosphoglucose-dependent alpha-1,2 glucosyltransferase of the ER OS=Geotrichum candidum GN=BN980_GECA08s00813g PE=4 SV=1 |
| UniRef50_A0A0J9XBG7 | 34.596% | 581 | 5.08e-67 | Similar to Saccharomyces cerevisiae YGR227W DIE2 Dolichyl-phosphoglucose-dependent alpha-1,2 glucosyltransferase of the ER n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XBG7_GEOCN |
| A0A1E3PMG0_9ASCO | 32.252% | 555 | 7.43e-69 | Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_57500 PE=4 SV=1 |
| A0A060THT2_BLAAD | 31.634% | 569 | 1.30e-51 | ARAD1D40436p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D40436g PE=4 SV=1 |
| A0A1E4TBP8_9ASCO | 29.358% | 545 | 4.22e-49 | Glycosyltransferase family 59 protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_3817 PE=4 SV=1 |
| ALG10_YEAST | 27.539% | 581 | 5.35e-41 | Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=DIE2 PE=1 SV=2 |
| ALG10_CANAL | 30.063% | 479 | 8.67e-36 | Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=DIE2 PE=3 SV=1 |
| ALG10_YARLI | 30.479% | 397 | 6.87e-33 | Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=ALG10 PE=3 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0351
Protein family membership
- Alpha-2-glucosyltransferase Alg10 (IPR016900)
Domains and repeats
None predicted.
Detailed signature matches
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PIRSF028810 (Alg10)
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PF04922 (DIE2_ALG10)
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no IPR
Unintegrated signatures
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CYTOPLASMIC_D... (C...)
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NON_CYTOPLASM... (N...)
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SIGNAL_PEPTIDE (Sig...)
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SIGNAL_PEPTID... (S...)
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SIGNAL_PEPTID... (S...)
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SIGNAL_PEPTID... (S...)
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TRANSMEMBRANE (Tran...)
Protein sequence
>MIA_00334_1 MPLFAAPLIYGTTLAVSIPIFAAVCQNLPVPYLDEVFHAPLTQRYIATLDLTQWDPMITTPPGLYWLATLYSYGLARPVI GVFRRFDSAAVAASGGFGRMAAAIAALDFGDLWVLRSLNLVGALVILPVVLNLLYASQTALQGAGKKQGTQRKQQEQPPV ETSYASIIMFPLVYFFAFLYYTDVWSAILVLAALAVGQSALAKDPQKQTFSGSVVASQVRWIFASAILALLSLTFRQTNI VWAGYVALTLLEIQANKTALNQPQSSQPPTFVARLGGIVSTALDWRSPVSRAITLGYGAVAAAFIAFLVWNNGAITLGDQ AHHQISANIGQIFYLALHAAFFFGPPLAIYAAVTVARTGQLPVRPKSAAIVAVGFVVSSILVAGALHTVAFSAPLHPHPF TLADNRHYTFYLWRRVLSPCRASFGAALVRAPVFTAGFAILIAPLALAFTSSNKKATTVFSILAFIAAIAATLIPSPLLE PRYYIVPLVLWRVCHFAPTFDSLFQVKESEEDQGHVPEKQTLLDRIVFQDIEFLYYGYINVITLIVFLCYPFTWASEPGM LQRFMW
GO term prediction
Biological Process
GO:0006488 dolichol-linked oligosaccharide biosynthetic process
Molecular Function
GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity
Cellular Component
GO:0005789 endoplasmic reticulum membrane