Protein
MCA_01091_1
Length
663 amino acids
Gene name: ALG10
Description: Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase
Browser: contigA:3479199-3481191+
RNA-seq: read pairs 1816, FPKM 33.8, percentile rank 55.9% (100% = highest expression)
Protein function
| Annotation: | ALG10 | Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase | |
|---|---|---|---|
| KEGG: | K03850 | ALG10 | alpha-1,2-glucosyltransferase [EC:2.4.1.256] |
| EGGNOG: | 0PKSX | ALG10 | Adds the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(2)Man(9)GlcNAc(2)-PP-Dol |
| SGD closest match: | S000003459 | DIE2 | Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase |
| CGD closest match: | CAL0000181033 | DIE2 | Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_00334_1 | 37.38% | 428 | 4e-65 | MIA_00334_1 |
| A0A1E3PMG0_9ASCO | 31.58% | 608 | 2e-58 | Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_57500 PE=4 SV=1 |
| UniRef50_A0A1E3PMG0 | 31.58% | 608 | 5e-55 | Uncharacterized protein n=1 Tax=Nadsonia fulvescens var. elongata DSM 6958 TaxID=857566 RepID=A0A1E3PMG0_9ASCO |
| ALG10_YARLI | 27.42% | 620 | 1e-47 | Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=ALG10 PE=3 SV=1 |
| A0A0J9XBG7_GEOCN | 27.71% | 646 | 6e-47 | Similar to Saccharomyces cerevisiae YGR227W DIE2 Dolichyl-phosphoglucose-dependent alpha-1,2 glucosyltransferase of the ER OS=Geotrichum candidum GN=BN980_GECA08s00813g PE=4 SV=1 |
| A0A1E4TBP8_9ASCO | 26.43% | 628 | 2e-45 | Glycosyltransferase family 59 protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_3817 PE=4 SV=1 |
| ALG10_CANAL | 23.83% | 596 | 2e-26 | Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=DIE2 PE=3 SV=1 |
| A0A060THT2_BLAAD | 28.22% | 326 | 2e-24 | ARAD1D40436p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D40436g PE=4 SV=1 |
| ALG10_YEAST | 28.22% | 443 | 2e-23 | Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=DIE2 PE=1 SV=2 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.7998
Predicted cleavage: 15
Protein family membership
- Alpha-2-glucosyltransferase Alg10 (IPR016900)
Domains and repeats
None predicted.
Detailed signature matches
-
-
PF04922 (DIE2_ALG10)
-
no IPR
Unintegrated signatures
-
CYTOPLASMIC_D... (C...)
-
NON_CYTOPLASM... (N...)
-
-
TRANSMEMBRANE (Tran...)
-
mobidb-lite (disord...)
Protein sequence
>MCA_01091_1 MAKSSKHRNSPPRGKGTKSTSSHSKRNWKLAKYVPSTNKFIYILTVLSSMLGAFFVSDAVRRPYLDEVFHIPLASHYCNT FDFTKWDPKVTTPPGLYWFATAYAQLLIKPVVIITQILKNNLGASFPIIGDNIIVSYLSKIDPCSLDVLRSFNTMGLLIA FPLALTLLHKSQRSLNKHYGFDNANNTINTHYASLISFPLMYFFSFLFYTDVWSAIWVVFSLALGKYALTKTIHQVTHTT PTSVKVTHQSEWTDSAATLLILSSVCSIISLTFRQTNIVWTGYIVVSLVEDAGLLLQSIENRNKEEKSKKKGVSILRQDI FSFFSVMTYNMVSHGLPIILSFGPAFGLFAVFLTINEGITLGDKSNHEIAINFGQLLYLIFHLALFEGPVYVFVKIFNFL VSFVRGNQNEKVRSKLSFSLGRFLIKLFLLTISFISMTTLLHSNYGYSEDAHPFTLSDNRHYTFYIWRRIIQPCKDTSLV FNSSNTGFISKNRSVIELFETLDKNVPQIASFIRNNLELGMVYSAICAPFYMLGAWLLFPRGSNSASGITAYTNATYRTV SRIMFIVCICASLVPSPLLEPRYYMIPIIIWRTCHSPVFTKTETSVSSVSSAASSKIFSWRKQWPVLLEFFWYGFINFLT VSLFLFRTFKWPSEPTNKQRFMW
GO term prediction
Biological Process
GO:0006488 dolichol-linked oligosaccharide biosynthetic process
Molecular Function
GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity
Cellular Component
GO:0005789 endoplasmic reticulum membrane