Protein

MIA_00281_1

Length
159 amino acids

Browser: contig01:802742-803317-

Protein function

EGGNOG:0PMVKFIS1Has a role in mitochondrial fission. Has a role in outer membrane fission but not matrix separation (By similarity)
SGD closest match:S000001327FIS1Mitochondrial fission 1 protein
CGD closest match:CAL0000185855FIS1Mitochondrial fission 1 protein

Protein alignments

%idAln lengthE-value
MCA_05403_187.023%1315.80e-79MCA_05403_1
A0A0J9X7R9_GEOCN66.929%1275.36e-63Mitochondrial fission 1 protein OS=Geotrichum candidum GN=BN980_GECA04s07017g PE=3 SV=1
A0A060TDS1_BLAAD64.286%1265.92e-57Mitochondrial fission 1 protein OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D02398g PE=3 SV=1
FIS1_YARLI59.542%1314.90e-54Mitochondrial fission 1 protein OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=FIS1 PE=3 SV=2
A0A1E3PIT6_9ASCO58.779%1313.07e-52Mitochondrial fission 1 protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_47023 PE=3 SV=1
UniRef50_Q4X0I856.667%1204.48e-44Mitochondrial fission 1 protein n=96 Tax=Pezizomycotina TaxID=147538 RepID=FIS1_ASPFU
FIS1_YEAST47.727%1324.53e-39Mitochondrial fission 1 protein OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=FIS1 PE=1 SV=1
FIS1_CANAL45.736%1291.53e-35Mitochondrial fission 1 protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=FIS1 PE=3 SV=2

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0200

Protein family membership

Domains and repeats

  1. Domain
  2. Repeat
1 20 40 60 80 100 120 140 159

Detailed signature matches

  1. Family IPR016543
    Mitochondria fission 1 protein
    1. PIRSF008835 (TPR_re...)
  2. Domain IPR011990
    Tetratricopeptide-like helical domain
    1. G3DSA:1.25.40.10
    2. SSF48452 (TPR-like)
  3. Domain IPR033745
    Mitochondria fission protein Fis1, cytosolic domain
    1. cd12212 (Fis1)
  4. Repeat IPR028058
    Fis1, N-terminal tetratricopeptide repeat
    1. PF14852 (Fis1_TPR_N)
  5. Repeat IPR028061
    Fis1, C-terminal tetratricopeptide repeat
    1. PF14853 (Fis1_TPR_C)
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. NON_CYTOPLASM... (N...)
  3. TMhelix
  4. TRANSMEMBRANE (Tran...)

Residue annotation

  1. heterodimer interf...

Protein sequence

>MIA_00281_1
MTEKFVLPGIQEINTPTSPISVEELEILRHQYYSEGQFVSLQTRFNYAWGLVRSQAVSDQQFGVKLLTDLFKDSPERRRE
VLYYLSIGNYKLQEYSKARKYADILLEIEPDNRQAAQLRQVIEDRLAKEGLIGVAITSGVIAAAAAAITFFAKYHNPRR

GO term prediction

Biological Process

GO:0000266 mitochondrial fission

Molecular Function

GO:0005515 protein binding

Cellular Component

None predicted.