Protein
MIA_00274_1
Length
269 amino acids
Browser: contig01:777606-778611+
Protein function
| EGGNOG: | 0PN2F | Component of the RPD3 histone deacetylase complex RPD3C(L) responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events | |
|---|---|---|---|
| SGD closest match: | S000000890 | DOT6 | Transcriptional regulatory protein DOT6 |
| CGD closest match: | CAL0000186480 | DOT6 | Dot6p |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| A0A0J9XGA6_GEOCN | 53.91% | 128 | 3e-29 | Uncharacterized protein OS=Geotrichum candidum GN=BN980_GECA14s03343g PE=4 SV=1 |
| UniRef50_A0A0J9XGA6 | 53.91% | 128 | 7e-26 | Uncharacterized protein n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XGA6_GEOCN |
| A0A161HKC7_9ASCO | 92.68% | 41 | 9e-21 | Tod6p OS=Sugiyamaella lignohabitans GN=TOD6 PE=4 SV=1 |
| MCA_02664_1 | 87.50% | 40 | 4e-19 | MCA_02664_1 |
| A0A060SW49_BLAAD | 85.37% | 41 | 4e-19 | ARAD1A02178p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A02178g PE=4 SV=1 |
| Q6CD94_YARLI | 82.93% | 41 | 2e-18 | YALI0C02629p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C02629g PE=4 SV=1 |
| A0A1E3PGY0_9ASCO | 82.93% | 41 | 4e-18 | Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83601 PE=4 SV=1 |
| DOT6_YEAST | 75.61% | 41 | 9e-17 | Transcriptional regulatory protein DOT6 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=DOT6 PE=1 SV=1 |
| A0A1E4TJ43_9ASCO | 78.05% | 41 | 5e-17 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_318 PE=4 SV=1 |
| A0A1D8PS02_CANAL | 70.73% | 41 | 3e-14 | Dot6p OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=DOT6 PE=4 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.3580
Protein family membership
None predicted.
Domains and repeats
-
Domain
1
50
100
150
200
269
Detailed signature matches
no IPR
Unintegrated signatures
-
-
cd00167 (SANT)
-
mobidb-lite (disord...)
Residue annotation
-
DNA binding site c...
Protein sequence
>MIA_00274_1 MLRHLKEEKKLGWKEIAAYFPNRTTNACQFRWRRLVSGTLRSSSSTASLAQASSAPQAQVGHHGMDHSHYANGSYPDRPW SREEDELIAKRTDLRPDELALLLNGRSEHEILARRAHLAARSQRHRHSSSSTTLQSSASALPPLREGLSSHGLPPLSALA PGASRHSSRHSSSAMKRAKSEASFDGSRLPPPLAQQPVAGNGQCYPQYTQYAVPPQQYQQPQQSGATGGLSQDQIPANVA SSGRYYDPTRGTYLPQPPSSSAQQGTYYS
GO term prediction
Biological Process
None predicted.
Molecular Function
GO:0003677 DNA binding
Cellular Component
None predicted.