Protein
MCA_02664_1
Length
591 amino acids
Gene name: TOD6
Description: subunit of the RPD3L histone deacetylase complex; Myb-like HTH transcription factor
Browser: contigB:1986907-1989009-
RNA-seq: read pairs 684, FPKM 14.3, percentile rank 32.9% (100% = highest expression)
Protein function
| Annotation: | TOD6 | subunit of the RPD3L histone deacetylase complex; Myb-like HTH transcription factor | |
|---|---|---|---|
| EGGNOG: | 0PN2F | Component of the RPD3 histone deacetylase complex RPD3C(L) responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events | |
| SGD closest match: | S000000150 | TOD6 | Transcriptional regulatory protein TOD6 |
| CGD closest match: | CAL0000186480 | DOT6 | Dot6p |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| A0A161HKC7_9ASCO | 75.41% | 61 | 2e-24 | Tod6p OS=Sugiyamaella lignohabitans GN=TOD6 PE=4 SV=1 |
| UniRef50_A0A161HKC7 | 75.41% | 61 | 4e-21 | Tod6p n=1 Tax=Sugiyamaella lignohabitans TaxID=796027 RepID=A0A161HKC7_9ASCO |
| A0A0J9XGA6_GEOCN | 71.21% | 66 | 3e-23 | Uncharacterized protein OS=Geotrichum candidum GN=BN980_GECA14s03343g PE=4 SV=1 |
| A0A060SW49_BLAAD | 80.39% | 51 | 5e-23 | ARAD1A02178p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A02178g PE=4 SV=1 |
| Q6CD94_YARLI | 74.51% | 51 | 6e-21 | YALI0C02629p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C02629g PE=4 SV=1 |
| A0A1E3PGY0_9ASCO | 72.41% | 58 | 3e-20 | Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83601 PE=4 SV=1 |
| TOD6_YEAST | 69.39% | 49 | 3e-18 | Transcriptional regulatory protein TOD6 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TOD6 PE=1 SV=1 |
| A0A1E4TJ43_9ASCO | 70.83% | 48 | 1e-17 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_318 PE=4 SV=1 |
| A0A1D8PS02_CANAL | 68.09% | 47 | 1e-15 | Dot6p OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=DOT6 PE=4 SV=1 |
| MIA_00274_1 | 88.57% | 35 | 5e-16 | MIA_00274_1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.2613
Predicted cleavage: 103
Protein family membership
None predicted.
Domains and repeats
-
Domain
1
100
200
300
400
500
591
Detailed signature matches
no IPR
Unintegrated signatures
-
-
PF13921 (Myb_DNA-bi...)
-
cd00167 (SANT)
-
mobidb-lite (disord...)
Residue annotation
-
DNA binding site c...
Protein sequence
>MCA_02664_1 MLPSSSSSSSQSSSQSSSNRHNHHHHHLKPSQSLPHLSSTAAQQQQQQYYYYNNNQNQQMYHQTQRIPSISSMSSQYPDY YQQSSSSSISHKRHLSSSSQSSSSSSKHHHQSYQSSDNNNNKYYSTAYPPSSSSPSPMIVEYDQTLLQQQHHHSKSPALT AITGASSPSSSDRRKTPASWDPEDDARLRYLKEQRRLGWKEIAAYFPNRTTNACQFRWRRLVSGTLKSTPSTSSLPNSPS MQPHQLMSSSSHQAHLINHDYRTSSSNKLPPSSPQQYSSPPPASYPTPPHSAASTSPASTSSSSSQHSYSNWTKEEDSII LKHCDLSPEKLATLLHGRREHDIWNRKNDLLKHYSISSTSSSSSSSSIYSSSSTSSSSSTSSANPPYHDNSRYINHYSSS PSSSKSLSHRKSVSALPPLKEYPSSSNILPSISSMAAASSATLSPSSHHHRSAHHQSSTSSLSTVRNNSSSATLTPQKHS SLLSNNILPPIKFPKRSKSSSFEGLKLPPPATIATTMDSRQRSSSSRSAHHNSGYPIDSVMSPSSSSYHSSSSNLSTPSN TSNNNNNNNNNNSGMLYHRSSSSTLGYSSRR
GO term prediction
Biological Process
None predicted.
Molecular Function
GO:0003677 DNA binding
Cellular Component
None predicted.