Protein
MIA_00257_1
Length
1,336 amino acids
Browser: contig01:722222-726351+
Protein function
| EGGNOG: | 0PGJE | SSN2 | Component of the SRB8-11 complex. The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II- dependent transcription. The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex |
|---|---|---|---|
| SGD closest match: | S000002851 | SSN2 | Mediator of RNA polymerase II transcription subunit 13 |
| CGD closest match: | CAL0000184111 | SSN2 | Mediator of RNA polymerase II transcription subunit 13 |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MCA_01626_1 | 37.925% | 1234 | 0.0 | MCA_01626_1 |
| A0A060T1Q2_BLAAD | 26.312% | 1448 | 2.36e-109 | ARAD1A01980p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A01980g PE=4 SV=1 |
| UniRef50_A0A060T1Q2 | 26.312% | 1448 | 5.83e-106 | ARAD1A01980p n=1 Tax=Blastobotrys adeninivorans TaxID=409370 RepID=A0A060T1Q2_BLAAD |
| A0A161HGX7_9ASCO | 26.244% | 1387 | 7.66e-100 | Uncharacterized protein OS=Sugiyamaella lignohabitans GN=AWJ20_2690 PE=4 SV=1 |
| SSN2_YARLI | 26.762% | 908 | 2.39e-65 | Mediator of RNA polymerase II transcription subunit 13 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=SSN2 PE=3 SV=3 |
| A0A1E4TKI1_9ASCO | 29.425% | 435 | 5.95e-41 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_42867 PE=4 SV=1 |
| SSN2_CANAL | 23.878% | 624 | 3.10e-21 | Mediator of RNA polymerase II transcription subunit 13 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=SSN2 PE=3 SV=1 |
| SSN2_YEAST | 22.468% | 543 | 9.91e-20 | Mediator of RNA polymerase II transcription subunit 13 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SSN2 PE=1 SV=2 |
| A0A1E3PI44_9ASCO | 30.769% | 130 | 1.91e-11 | Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83169 PE=4 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0786
Protein family membership
- Mediator complex, subunit Med13 (IPR009401)
Domains and repeats
None predicted.
Detailed signature matches
-
-
PF06333 (Med13_C)
-
no IPR
Unintegrated signatures
-
CYTOPLASMIC_D... (C...)
-
NON_CYTOPLASM... (N...)
-
TRANSMEMBRANE (Tran...)
-
mobidb-lite (disord...)
Protein sequence
>MIA_00257_1 MSINLDNAHSNIFKAGNFTQIPYRVFIPPSPSPTTNNKELLYQAEWFIRKSIPTPLVAIIGHELWFFSLQPSFPKTISAE SLGLTETSTGIFIPSMMLQDHHAPPAPYVPFITAVKSLIFHSLCQFDILIPLGPVLINLTNGNLLNIEPSLLPFGDLILK IYHQKSGLFKLSHAIETCNSSSKPLQIPSKIILSPIGIPASFISMISPPKSVKGFVNLLMCSYGIKIEDTRLASMDWASF NISPPTTNPIIISWPMDFCFCQPPFKQKIDNDLLWFRSNDIISQVESHMNDLQAIASLDHDYNKLNENDRTNDNDTNDNK RQANGFGLVSKDFTDSLSINLSENASHIFNNHLISQQPLRMTGMGPLMIYPTPPDPTLRSRPDINEQDHAINDSTPGKSS KNWDDLEEDLFGDAQEITEDDFNYFDDQKEEVTLNPIPEEPNIELASSAQSRDKIEDIKSQSSASTNSSTFQWPMPFASR QEIEVKPSQPLEDVSILSNVFNTDRRSHIFSPLKFHSSISDKLDSKYSRGGRYFVEPGTLDEVEEDSENEENGEDASKPL GCNNNILKAGPSFEVKVASKTRTDVQDLKRKHDEANLSETDDDIVSKKLATGWFNLLSQSRIVGKLNPIFFLPGVDIKAS DSQIFDSTIEVLLHQVVWDDGMFSNIISSALVPQYIKDTPLLDSLKAIFPQIEQLYLSQILSLAEGRDAQSNAAAITSLP SSGMNSPVSLNRQDSLPPSNLLHGNDMTPLPNPQTRPQSRTSLFPDSMETPANNYDVFTDSPKLINASSKNPLSGSFPQA EQPIVQPAPPRLRPELKVLFSIEAPHYTIMRMNQTLKAKSPILRFWKVFGLEPKNGKKAISVIMLSPGGKNSCKESSYFL QSLKSAYDSSGLGVLTLLKSKSTFEGIIPVSYQGQNLDHALETMRQTIISLSRELKSDAPKPQNLVVIIADPFLSILSLM AFSQAFVQFKREYLADEENGLDRFNVILKIIPVDIFASCDSLNVPSQYKMVRLALDLYERCPVVGENALGTSHRLISESL QTQRRCPAFTLSRLPPNKINFKFSRKPSPMILEEDSFLHIAYSVSENRKWLVSSWSDQYGEISKVEAFCLVKAEGQIRMP EEVCPEIWQKTLALISHIPVHWKITIAKLGWIDEDEINMWKGFASSSGKMISSLYILSVNTKPSFMITGNDSKSQDESSQ FSMPMAGTPQGVGNATEKDAGEEAVIVDSQNEIYGVLLKHETGSISPFLTSFRAPTQLMTGYLMKTESNGHDIGVFEATL VHSGTSPGETMRAILVQYRHLASLGATTGVETRVGSISPWHVYAVDKALRVLLHIF
GO term prediction
Biological Process
GO:0006357 regulation of transcription from RNA polymerase II promoter
Molecular Function
GO:0001104 RNA polymerase II transcription cofactor activity
Cellular Component
GO:0016592 mediator complex